81. American Family Physician: Gastric Cancer: Diagnosis And Treatment Options Full text of the article, gastric cancer diagnosis and treatment options from American Family Physician, a publication in the field of Health Fitness, http://www.findarticles.com/p/articles/mi_m3225/is_5_69/ai_114023736

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles American Family Physician March 1, 2004 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Related Searches Gastrointestinal cancer / Diagnosis Gastrointestinal cancer / Reports Gastrointestinal cancer / Risk factors Stomach cancer / Diagnosis ... Stomach cancer / Risk factors Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Gastric cancer: diagnosis and treatment options American Family Physician March 1, 2004 by John C. Layke Peter P. Lopez Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it.

82. Bone Marrow -Derived Stem Cells Linked To Gastric Cancers - UMass Medical School Previous studies of H. pylori inflammation and gastric cancers have focused on gastric cancers kill approximately 12000 people in the US each year. http://www.umassmed.edu/pap/news/2004/11_25_04.cfm

directory contacts index this section only Home News Bureau News Makers Publications ... news BONE MARROW-DERIVED STEM CELLS LINKED TO GASTRIC CANCERS New thinking on the source of gastric cancer November 25, 2004 WORCESTER, Mass .-In a study published in the November 26 issue of the journal Science that provides a radically different view of the origins of gastric cancers, researchers at the University of Massachusetts Medical School identified a clear and unexpected link between stomach cancer and bone marrow-derived cells. JeanMarie Houghton, MD, PhD, an assistant professor in medicine and cancer biology at UMMS, and colleagues discovered that infection with Helicobacter felis (a bacterium related to Helicobacter plyori, which has long been understood to cause chronic inflammation and cancer in the lining of the stomach) leads to a vast influx of bone marrow-derived stem cells as the body tries to repair the damage caused by the bacterial infection. Houghton and colleagues showed that this flood of bone marrow-derived stem cells (BMDCs) can actually spark stomach cancer tumors. Previous studies of H. pylori inflammation and gastric cancers have focused on damaged epithelial cells that line the stomach as the source of tumors. Houghton and colleague Timothy C. Wang, MD, formerly of UMMS and now at Columbia University Medical Center, showed that in mouse models it is the BMDCs themselves that form cancers, an unexpected development that may cause a shift in thinking about the formation and progression of such cancers.

83. Gastric Cancer gastric cancer studies focus on prolonging survival and finding molecular markers for targeted therapies. http://www2.mdanderson.org/depts/oncolog/articles/04/4-apr/4-04-1.html

From OncoLog, April 2004, Vol. 49, No. 4 Printer-friendly version Gastric Cancer Studies Focus on Prolonging Survival and Finding Molecular Markers for Targeted Therapies by Katie Prout Matias Dr. Jaffer Ajani , a professor in the Department of Gastrointestinal Medical Oncology, examines computed tomography scans, an important tool in gastric cancer clinical trials. During the last century, the incidence of gastric cancer in the western hemisphere decreased dramatically with the advent of better nutrition, refrigeration, and lower rates of Helicobacter pylori infection. What used to be the number one cause of cancer-related death among U.S. men is now uncommon, with about 21,000 cases diagnosed annually in the United States. Because patients are not typically screened for gastric cancer, most cases are diagnosed at a late stage, and many patients in whom it develops die of the disease. Localized cancer The five-year overall survival rates for patients with localized gastric cancer are daunting: 78% for patients with stage Ia cancer, 58% for stage Ib, 34% for stage II, 20% for stage IIIa, and 8% for stage IIIb. Currently, the only known curative therapy for nonmetastatic gastric cancer is a gastrectomy performed by experienced surgeons. However, even with successful surgery, the five-year survival rate is approximately 35%; with adjuvant chemoradiotherapy in selected patients, the survival rate is 40%. To improve survival rates in patients with localized gastric cancer, clinicians and researchers at The University of Texas M. D. Anderson Cancer Center have developed a strategy for treating select patients with preoperative therapy, a practice that is still investigational, cautioned Jaffer Ajani, M.D., a professor in the Department of Gastrointestinal Medical Oncology. In an ongoing clinical trial at M. D. Anderson, patients with operable gastric cancer are receiving chemotherapy followed by chemoradiotherapy followed by surgery.

84. Chemotherapy For Advanced Gastric Cancer (Cochrane Review) Abstract of a systematic review of the effects of health care prepared by the Cochrane Collaboration. http://www.cochrane.org/cochrane/revabstr/AB004064.htm

From The Cochrane Library, Issue 2, 2005 Chemotherapy for advanced gastric cancer (Cochrane Review) Wagner AD, Grothe W, Behl S, Kleber G, Grothey A, Haerting J, Fleig WE ABSTRACT What's new in this issue Search abstracts Browse alphabetical list of titles Browse by Review Group A substantive amendment to this systematic review was last made on 20 December 2004. Cochrane reviews are regularly checked and updated if necessary. Background: Gastric cancer currently ranks second in global cancer mortality. Most patients are either diagnosed at an advanced stage, or develop a relapse after apparently curative operation. Apart from supportive measures, systemic chemotherapy is the only treatment option available in this situation. Objectives: To assess the effect of chemotherapy versus best supportive care, combination versus single agent chemotherapy and different combination chemotherapy regimens in advanced gastric cancer. Search strategy: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 1, 2004), MEDLINE and EMBASE up to February 2004 and reference lists of articles. We also contacted pharmaceutical companies as well as national and international experts. Selection criteria: Randomised controlled trials on systemic intravenous chemotherapy versus best supportive care, combination versus single agent chemotherapy and different combination chemotherapies in advanced gastric cancer.

85. Wilson's Disease Gastroenterology Hematology and Oncology Stomach Cancer. http://www.fpnotebook.com/GI64.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Gastroenterology Hematology and Oncology Bowel ... Gastric Cancer Assorted Pages Carcinoid Syndrome Hepatic Adenoma Hepatocellular Carcinoma Hepatic Focal Nodular Hyperplasia ... Colorectal Cancer Screening Wilson's Disease Hepatolenticular Degeneration Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Gastroenterology Index Bowel Cirrhosis Constipation Cardiovascular Medicine Dermatology Diarrhea Esophagus Examination Gynecology Hematology and Oncology Hepatitis Inflammatory Bowel Disease Infectious Disease Laboratory General Malabsorption Neurology Neonatology Obstetrics Pancreas Pediatrics Pharmacology Prevention Procedure Psychiatry Peptic Ulcer Disease Radiology Rectum Rheumatology Spleen Stomach Surgery Symptom Evaluation Page Hematology and Oncology Index Bowel Cancer Carcinoid Cirrhosis Hemochromatosis Constipation Diarrhea Esophagus Barrett's Hepatic Adenoma Hepatic Carcinoma Primary Hepatic Focal Nodular Hyperplasia Hepatic Hemangioma Stomach Cancer Wilsons Disease Pathophysiology Autosomal Recessive disease Defect in copper excretion into bile Copper accumulates from ceruloplasmin cleavage Initially excessive copper accumulates in liver

86. BioMed Central | Full Text | Phospholipids Reduce Gastric Cancer Cell Adhesion T The human gastric cancer cell line NUGC4 was purchased from the Japanese Cancer For adhesion experiments gastric cancer cells were detached with http://www.biomedcentral.com/1471-230X/4/33

home journals A-Z subject areas advanced search ... Volume 4 Viewing options Abstract Full text PDF Associated material: Pre-publication history PubMed record Related literature: Articles citing this article on Google Scholar on ISI Web of Science Other articles by authors ... Similar articles (PubMed) Tools: E-mail to a friend Download references Post a comment Key E-mail Corresponding author Research article Phospholipids reduce gastric cancer cell adhesion to extracellular matrix in vitro Marc Jansen Karl-Heinz Treutner Britta Schmitz Jens Otto Petra Lynen Jansen S Neuss and Volker Schumpelick Department of Surgery, University Clinic, Pauwelsstr. 30, 52057 Aachen, Germany Interdisciplinary Centre of Clinical Research (IZKF) Biomat; University Clinic, Pauwelsstr. 30, 52057 Aachen, Germany Institute of Pathology, University Clinic, Pauwelsstr. 30, 52057 Aachen, Germany BMC Gastroenterology The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-230X/4/33 Received Accepted Published This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0

87. National Cancer Institute - Gastric Cancer Treatment Expertreviewed information summary about the treatment of gastric cancer. http://www.nci.nih.gov/cancertopics/pdq/treatment/gastric/patient

var bSearchBoxBool=false; Last Modified: General Information About Gastric Cancer Stages of Gastric Cancer Recurrent Gastric Cancer Treatment Option Overview Treatment Options by Stage ... About PDQ Page Options Print This Page Print Entire Document View Entire Document E-Mail This Document Quick Links Director's Corner Dictionary of Cancer Terms NCI Drug Dictionary Funding Opportunities ... NIH Calendar of Events NCI Highlights NCI Offers Support for Those in Need After Katrina NCI Announces Plan to Fight Lung Cancer National Prostate Cancer Awareness Month National Ovarian Cancer Awareness ... Past Highlights General Information About Gastric Cancer Key Points for This Section Gastric cancer is a disease in which malignant (cancer) cells form in the lining of the stomach. Age, diet, and stomach disease can affect the risk of developing gastric cancer. Possible signs of gastric cancer include indigestion and stomach discomfort or pain. Tests that examine the stomach and esophagus are used to detect (find) and diagnose gastric cancer. ... Certain factors affect prognosis (chance of recovery) and treatment options. Gastric cancer is a disease in which malignant (cancer) cells form in the lining of the stomach. The stomach is a J-shaped organ in the upper abdomen . It is part of the digestive system , which processes nutrients vitamins minerals carbohydrates , fats, proteins , and water) in foods that are eaten and helps pass waste material out of the body. Food moves from the

88. Clinical Trial: Vaccine Therapy In Treating Patients With Gastric, Prostate, Or gastric cancer ovarian epithelial cancer Prostate Cancer, Drug EGFR antisense DNA Drug keyhole limpet hemocyanin Drug sargramostim http://www.clinicaltrials.gov/ct/show/NCT00023634

Home Search Browse Resources ... About Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer This study is currently recruiting patients. Verified by National Cancer Institute (NCI) June 2005 Sponsors and Collaborators: Southwest Oncology Group National Cancer Institute (NCI) Information provided by: National Cancer Institute (NCI) ClinicalTrials.gov Identifier: Purpose RATIONALE: Vaccines made from a peptide may make the body build an immune response to kill cancer cells. PURPOSE: This phase I trial is studying two different vaccines to treat patients who have gastric, prostate, or ovarian cancer. Condition Intervention Phase adult brain tumor Gastric Cancer ovarian epithelial cancer Prostate Cancer Drug: EGFR antisense DNA Drug: keyhole limpet hemocyanin Drug: sargramostim Procedure: antisense therapy Procedure: biological response modifier therapy Procedure: non-specific immune-modulator therapy Procedure: non-tumor cell derivative vaccine Procedure: vaccine therapy Phase I MedlinePlus related topics: Brain Cancer Ovarian Cancer Prostate Cancer Stomach Cancer Study Type: Interventional Study Design: Treatment Official Title: Phase I Study of EGFRvIII Peptide Vaccine With Sargramostim (GM-CSF) Versus Keyhole Limpet Hemocyanin as Adjuvant in Patients With EGFRvIII-Expressing Cancer Further Study Details: OBJECTIVES: Determine the toxicity of EGFRvIII peptide vaccine with sargramostim (GM-CSF) or keyhole limpet hemocyanin (KLH) as adjuvant in patients with EGFRvIII-expressing cancer.

89. Disease Category Listing (340): Stomach Cancer CenterWatch Listing of Clinical Research Trials for Stomach Cancer. CisplatinPaclitaxel Containing Chemoradiation Regimens in Resected gastric cancers. http://www.centerwatch.com/patient/studies/cat340.html

Clinical Trials: Stomach Cancer California Duarte; City of Hope National Medical Center CALGB 80101: Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesophageal Adenocarcinoma Georgia Savannah; Memorial Health Research Center A Randomized Phase II Comparison Of Two Cisplatin-Paclitaxel Containing Chemoradiation Regimens in Resected Gastric Cancers.(RTOG G-0114) Kentucky Lexington; Central Baptist Hospital Clinical Research Center CALGB 80101: A Phase III Trial of Adjuvant Chemoradiation after Resection of Gastric and Gastroesophageal Adenocarcinoma Texas Houston; S. R. Burzynski Clinic Phase II Study Of Antineoplastons A10 And AS2-1 In Patients With Adenocarcinoma Of The Stomach Houston; S. R. Burzynski Clinic Phase II Study Of Antineoplastons A10 And AS2-1 In Patients With Carcinoma Of The Small Intestine Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: September 7, 2005 at 2:39:52 PM

90. NEJM -- Green Tea And The Risk Of Gastric Cancer In Japan Original Article from The New England Journal of Medicine Green Tea and the Risk of gastric cancer in Japan. http://content.nejm.org/cgi/content/short/344/9/632

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 344:632-636 March 1, 2001 Number 9 Next Green Tea and the Risk of Gastric Cancer in Japan Yoshitaka Tsubono, M.D., Yoshikazu Nishino, M.D., Shoko Komatsu, M.D., Chung-Cheng Hsieh, Sc.D., Seiki Kanemura, M.D., Ichiro Tsuji, M.D., Haruo Nakatsuka, Ph.D., Akira Fukao, M.D., Hiroshi Satoh, M.D., and Shigeru Hisamichi, M.D. Full Text PDF Editorial by Sano, T. ... PubMed Citation ABSTRACT Background studies have suggested that the consumption of green tea provides protection against gastric cancer, few prospective studies have been performed. Methods In January 1984, a total of 26,311 residents in three municipalities of Miyagi Prefecture, in northern Japan (11,902 men and 14,409 women 40 years of age or older), completed a self-administered questionnaire that included questions about the frequency of consumption of green tea. During 199,748 person-years of follow-up, through December 1992, we identified 419 cases of gastric cancer (in 296 men and 123 women). We used Cox regression

91. Gastric Breast Cancer Network Center Provides access to secondaryresearch articles on carcinogenesis-based prevention, early detection, evidence-based current treatment and future directions. http://www.gastricbreastcancer.com

92. Stomach (Gastric) Cancer UK charity offers information including prevention, diagnosis and treatment. Also provides details on fundraising. http://www.cancerhelp.org.uk/help/default.asp?page=3887

93. Stomach (gastric) Cancer This section gives answers to some of the general questions we ve been asked about stomach (gastric) cancer. If you need to find out anything specific about http://www.cancerhelp.org.uk/help/default.asp?page=277

94. InteliHealth: Gastric (stomach) Cancer InteliHealth Featuring Harvard Medical School s consumer health information. For more than 550 diseases and conditions, learn What Is It?, Symptoms, http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10051.html

chrome_imgPreload('gifChr_mid_but_home_mo_1','http://img.intelihealth.com/i/C/Chr_mid_but_home-o.gif'); chrome_imgPreload('gifChr_mid_but_comm_mo_2','http://img.intelihealth.com/i/C/Chr_mid_but_comm-o.gif'); chrome_imgPreload('gifChr_mid_but_dental_mo_3','http://img.intelihealth.com/i/C/Chr_mid_but_dental-o.gif'); chrome_imgPreload('gifChr_mid_but_drug_mo_4','http://img.intelihealth.com/i/C/Chr_mid_but_drug-o.gif'); chrome_imgPreload('gifChr_mid_but_askexpert_mo_5','http://img.intelihealth.com/i/C/Chr_mid_but_askexpert-o.gif'); chrome_imgPreload('gifChr_mid_but_medical_mo_6','http://img.intelihealth.com/i/C/Chr_mid_but_medical-o.gif'); chrome_imgPreload('gifChr_mid_but_chats_mo_7','http://img.intelihealth.com/i/C/Chr_mid_but_chats-o.gif'); chrome_imgPreload('gifchr_mid_but_news_mo_8','http://img.intelihealth.com/i/c/chr_mid_but_news-o.gif'); chrome_imgPreload('gifChr_mid_but_privacy_mo_9','http://img.intelihealth.com/i/C/Chr_mid_but_privacy-o.gif'); Advertisement Stomach Cancer What Is It? Symptoms Diagnosis Expected Duration ... Additional Info What Is It? Stomach cancer, also called gastric cancer, is the uncontrolled growth of abnormal cells in the lining of the stomach. The disease usually does not cause any symptoms until the later stages, and usually, by the time stomach cancer is diagnosed, the prognosis is poor. Most people who are diagnosed with stomach cancer are over the age of 60. The disease rarely occurs before age 50, and it is more common in men than women.

95. Sloan-Kettering - Gastric (Stomach) Cancer At Memorial SloanKettering cancer Center, our Upper Gastrointestinal Disease Management Team focuses on cancers of the esophagus, stomach, and pancreas, http://www.mskcc.org/mskcc/html/1467.cfm

if(!window.tabs) var tabs = []; var tab = tabs[tabs.length] = []; tab.id = 13; var TAB_WWWROOT = "/mskcc/"; var tabDarkColor = "#336699"; var tabMediumColor = "#99BBCC"; if(window.createHeaderImageCache) createHeaderImageCache(44,512,5626,1072,5664,638,8228); if(window.formatTabs) formatTabs(tabs); Cancer Information Types of Cancer Gastric (Stomach) Cancer Gastric (Stomach) Cancer Select a Gastric (Stomach) Cancer Topic - Overview - Risk Factors - Symptoms - Diagnosis - Treatment - Clinical Trials Memorial Sloan-Kettering is one of the few National Cancer Institute-designated cancer centers with a specific program in treating cancers of the upper gastrointestinal tract, and our investigators have made many of the major advances in the treatment of these diseases. In this section you can find information about our expertise in treating patients with cancers of the stomach, our services, and our research. Memorial Sloan-Kettering is one of the few National Cancer Institute-designated cancer centers with a specific program in treating cancers of the upper gastrointestinal tract, and our investigators have made many of the major advances in the treatment of these diseases. Overview The stomach is a J-shaped organ in the upper abdomen where digestion begins before food is passed to your intestines.

96. Stomach Cancer Information, Stomach Cancer, Gastric Carcinoma Information about how to receive an individualized report which discusses stomach cancer treatment optionsmainstream, experimental, http://www.thehealthresource.com/cancer_info/stomach_cancer.html

Stomach Cancer (Gastric Cancer) Receive an individualized report which discusses treatment options-mainstream, experimental, and alternative/complementary-and top specialists in the treatment of stomach cancer. Your report will focus on your individual condition based on the information you have at this point in time. You will also receive "models of hope" of case histories of people who have survived stomach cancer. Look at the terms below to find those which describe your situation. Definition of Stomach Cancer: Cancer of the stomach, also called gastric cancer or gastric carcinoma, is a disease in which cancer (malignant) cells are found in the tissues of the stomach. Stomach cancer can develop in any part of the stomach and may spread throughout the stomach and to other organs. It may grow along the stomach wall into the esophagus or small intestine. Grades of Stomach Cancer: Grade indicates how the cancer cells look under a microscope and how quickly they are likely to grow and spread.

97. Stomach (Gastric) Cancer Stomach cancer is a disease in which malignant (cancer) cells form in the lining of the stomach. One of the symptoms can be chronic heartburn. http://heartburn.about.com/b/a/176532.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a42' About Heartburn / Acid Reflux Heartburn / Acid Reflux Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Heartburn / Acid Reflux newsletter! See Online Courses Search Heartburn / Acid Reflux Stomach (Gastric) Cancer Heartburn Blog Main From Sharon Gillson Your Guide to Heartburn / Acid Reflux FREE Newsletter. Sign Up Now! June 10, 2005 Stomach (Gastric) Cancer Stomach cancer is a disease in which malignant (cancer) cells form in the lining of the stomach. One of the symptoms can be chronic heartburn. What is Stomach Cancer? Symptoms of Stomach Cancer Diagnosing Stomach Cancer Stages of Stomach Cancer ... Read Archives powered by Movable Type Advertisement Most Popular GERD Screening Quiz Safe Foods For Heartburn Diet Foods You Should Avoid Hiatal Hernia Screening Quiz ... Foods to Eat With Discretion What's Hot Symptoms of Ulcers Symptoms of GERD Achalasia Gastritis Screening Quiz ... Oven-Fried Chicken adunitCM(150,100,'x55') Topic Index Email to a Friend Our Story Be a Guide ... Patent Info.

98. Stages Of Stomach (Gastric) Cancer After stomach cancer has been diagnosed, tests are done to find out if cancer cells have spread within the stomach or to other parts of the body. http://heartburn.about.com/od/otherdigestivedisorder1/a/stomcanstages.htm

var zLb=0; zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a42' About Heartburn / Acid Reflux Other Digestive Diseases Stages of Stomach (Gastric) Cancer Heartburn / Acid Reflux Essentials Digestive Disorders Screening Quizzes Symptoms ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Heartburn / Acid Reflux newsletter! See Online Courses Search Heartburn / Acid Reflux Stay up to date! Compare Prices Email to a friend ... Print this page Most Popular GERD Screening Quiz Safe Foods For Heartburn Diet Foods You Should Avoid Hiatal Hernia Screening Quiz ... Foods to Eat With Discretion What's Hot Symptoms of Ulcers Symptoms of GERD Achalasia Gastritis Screening Quiz ... Oven-Fried Chicken adunitCM(150,100,'x55') Stages of Stomach (Gastric) Cancer From Sharon Gillson Your Guide to Heartburn / Acid Reflux FREE Newsletter. Sign Up Now! After gastric cancer has been diagnosed, tests are done to find out if cancer cells have spread within the stomach or to other parts of the body. The process used to find out if cancer has spread within the stomach or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment.

99. Stomach (Gastric) Cancer Stomach cancers are classified according to their tissue type. Overwhelmingly, the most common type of stomach cancers are gastric adenocarcinomas, http://www.cancersupportivecare.com/stomach.html

Fifth Dimension Table of Contents Stomach Cancer Andrew H. Ko, MD Types How it spreads What Causes It Diagnostic evaluation ... Important questions to ask your doctor Worldwide, stomach cancer (also referred to as gastric cancer) remains one of the most common forms of cancer, affecting approximately 800,000 new individuals annually. However, the rate of stomach cancer has been declining in the United States and western Europe over the past half-century, a trend which has been felt attributable in large part to changes in diet during this period of time. Interestingly, the incidence of cancers located in different portions of the stomach appear to be heading in opposite directions: while those located in the more distal (lower) portion of the stomach have been declining in incidence, there has actually been an increase in cases occurring in the proximal portion of the stomach (closer to the esophagus) and at the gastroesophageal junction (where the esophagus meets the stomach). Types Back to the Table of Contents Stomach cancers are classified according to their tissue type. Overwhelmingly, the most common type of stomach cancers are gastric adenocarcinomas , which arise from the glandular tissue lining the stomach. Occurring much more rarely are gastric lymphomas (also referred to as

100. New Research Shows Stomach (gastric) Cancer Originates From Bone Marrow Derived A new study from Columbia University Medical Center finds that stomach (gastric) cancer originates from bone marrow derived stem cells (BMDC), http://www.brightsurf.com/news/nov_04/EDU_news_112904_b.php

Brightsurf Science News Brightsurf via RSS Science News by E-Mail Search Brightsurf News ... Definitions Get Today's Science News and Events by E-mail Enter E-mail Address Search BrightSurf.com New research shows stomach (gastric) cancer originates from bone marrow derived stem cells November 29, 2004 Findings may aid diagnosis and indicate new treatment target for many cancers A new study from Columbia University Medical Center finds that stomach (gastric) cancer originates from bone marrow derived stem cells (BMDC), rather than from stomach stem cells, as previously thought. The study, "Gastric Cancer Originating from Bone Marrow-Derived Cells" is published in the current issue of Science. "This was an unexpected finding, which may lead to a re-evaluation of current assumptions about how all cancers originate," said Timothy C. Wang, M.D., chief, Division of Digestive and Liver Diseases and Dorothy L. and Daniel H. Silberberg Professor of Medicine at Columbia University College of Physicians and Surgeons and senior author of the study. "The implications of this study may lead to new methods of diagnosis and treatment of many cancers Ð particularly those that have been linked to chronic inflammation such as stomach, esophagus, lung, pancreas, liver, etc." A common assumption among cancer specialists is that most cancers originate from tissue stem cells Ð for example, the gastric stem cells contained in the lining of the stomach. However, the researchers suspected BMDC may contribute to the development or progression of cancer because they are frequently recruited to sites of tissue injury and inflammation, e.g., a typical site for cancer development.

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