TAR Syndrome - Wikipedia, The Free Encyclopedia tar syndrome (Thrombocytopenia and Absent Radius) is a rare genetic disorderwhich is characterised by the absence of the radius bone in the forearm, http://en.wikipedia.org/wiki/TAR_syndrome
Extractions: You did it! Over US$240,000 was donated in the 21-day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise TAR Syndrome (Thrombocytopenia and Absent Radius) is a rare genetic disorder which is characterised by the absence of the radius bone in the forearm, and a dramatically reduced platelet count. Platelets are the clotting agent in blood . A lowered count leads to bruising , and at worst, life-threatening haemorrhage . For most people with TAR, platelet counts improve as they grow out of childhood. Other common links between people with TAR seem to include heart problems, kidney problems, knee joint problems and frequently lactose intolerance Treatments range from platelet transfusions through to surgery aimed at 'normalising' the appearance of the arm, which is much shorter and 'clubbed.' There is some debate pro and anti surgery. The infant mortality rate has been curbed by new technology, including platelet transfusions, which can even be performed in utero . The critical period is the first year of life. Genetic research is underway. It is now known to involve an
TAR Syndrome Because of overlapping features in patients with tar syndrome, As a result,two cases with tar syndrome which are rarely seen are discussed with http://ams.cu.edu.tr/July2000Vol9No2/tar.htm
Extractions: Two New Cases of Thrombocytopenia-Absent Radii (TAR) Syndrome* Ercan Kýrými, MD, Nejat Narlý, MD, Mehmet Satar, MD. Thrombocytopenia-absent radii syndrome is characterized by the neonatal onset thrombocytopenia and bilateral absence or hypoplasia of the radii with normal or poorly formed hands and thumbs. In this paper, two unrelated female infants affected by thrombocytopenia-absent radii syndrome are described. At birth, bilateral micromelia of upper limbs, short and radially curved forearms and hypoplastic arms were observed in infants. A severe thrombocytopenia confirmed the clinical diagnosis of thrombocytopenia-absent radii syndrome. One of them died on 19 th day at home with hemorrhagic complications because she was discharged by her family. Other patient supported with thrombocyte suspensions is now eight months old and is still being followed closely at our outpatient department. As a result, two patients with thrombocytopenia-absent radii syndrome which are seen rarely discussed with physical, laboratory and follow specifications. Ann Med Sci 2000;9:78-81 Key words: Thrombocytopenia-absent radii syndrome.
Extractions: The Board classifies its publications into different types of document. This is a Review of knowledge . This means that the report is based on science and/or tried and tested experience. Reviews of knowledge shall, among other things, support knowledge-based care and treatment, method development and other work for improvement; shall stimulate and facilitate quality assurance and effective use of resources and/or elucidate effects of distribution. The Board is responsible for contents and conclusions. The disease/injury/diagnosis HTML-version: 1.0 English index Search The aphabetical list This is an excerpt from the database of the Swedish National Board of Health and Welfare on rare diseases. The concept of "rare diseases" is defined as: "Disorders resulting in extensive disability whick affect no more than 100 individuals in one million inhabitants". The ambition underlying the database is to provide information to the public, including patients and their families, as well as to health professionals. TAR is an acronym for Thrombocytopenia and Absent Radius, and TAR syndrome is characterised by a combination of low blood platelet (thrombocyte) count, and absent radius bones in the forearms. Shaw and Oliver were the first to describe the condition in
TAR-syndromet - Små Och Mindre Kända Handikappgrupper På tar syndrome Support Group´s hemsida på Internetadress www.ivh.se/TAR finnsinformation om Hall J. Thrombocytopenia and absent radius (TAR) syndrome. http://www.sos.se/smkh/2002-29-157/2002-29-157.htm
Extractions: HTML-version: 2.0 Socialstyrelsen Detta är ett utdrag ur Socialstyrelsens kunskapsdatabas om små och mindre kända handikappgrupper. Med små och mindre kända handikappgrupper avses ovanliga sjukdomar/skador som leder till omfattande funktionshinder och som finns hos högst 100 personer per miljon invånare. Syftet med databasen är att ge aktuell information om små och mindre kända handikappgrupper och om det stöd och den service som dessa grupper behöver. För ytterligare information om aktuell diagnos hänvisas till informationsmaterial, litteratur och databaser som anges under resp diagnos. t a r Orsak till sjukdomen/skadan Symtom Praktiska tips Resurspersoner tarsupportgroup@telia.com kerstin.wennstrom@ivh.se , Internetadress www.ivh.se/TAR dammert@sallsyntadiagnoser.nu
No Fear: Caleb's Story - York Daily Record tar syndrome (thrombocytopenia absent radius) is a rare genetic disorder, affectingabout four people per one million worldwide since it was originally http://ydr.com/page/caleb/tarsyndrome/
Extractions: @import url("/var/css/extended.css"); Browse About us Announcements Awards Calendar of Events ... No Fear: Caleb's Story ABOUT TAR SYNDROME TAR Syndrome (thrombocytopenia absent radius) is a rare genetic disorder, affecting about four people per one million worldwide since it was originally described in medical literature in 1951. The syndrome varies widely in its presentation, ranging from mild to severe structural anomalies and other medical problems. Babies with TAR may have a combination of shortened limbs, heart or kidney problems, mental retardation, a decreased production of platelets and bleeding disorders. While some cases are diagnosed prenatally through specialized blood tests or imaging techniques, most cases are diagnosed at birth. Dr. Charles Peterson, director of the blood diseases program at the National Heart, Lung and Blood Institute in Bethesda, Md., said the number of TAR cases does not include babies who die from the syndrome in utero before they are diagnosed. Although progress has been made toward the prenatal identification of babies with TAR, Peterson said, doctors have been unable to isolate the recessive gene that is the cause. Its so rare, you dont get a lot of families (with TAR) you can study, he said. top Main Local Sports ...
Tar Syndrome Complete online version of The Encyclopaedia of Medical Imaging including textand images from The Encyclopaedia of Medical Imaging s eight book volumes http://www.amershamhealth.com/medcyclopaedia/medical/Volume VII/TAR SYNDROME.asp
Extractions: financial services our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Tar syndrome, thrombocytopenia and absent radius syndrome. Clinical manifestations reflect the absent radius and the thrombocytopenia. Radiologically, there is an absent radius which may be associated with other upper limb deformities.
Tar Syndrome Complete online version of The Encyclopaedia of Medical Imaging including textand images from The Encyclopaedia of Medical Imaging s eight book volumes http://www.amershamhealth.com/medcyclopaedia/medical/Volume III 1/TAR SYNDROME.a
Extractions: financial services our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Tar syndrome, an acronym for an anaemia consisting of Thrombocytopenia with Absent Radius (see aplasia (III:1), Fig. 2 ). The syndrome resembles Fanconis anaemia and is characterized by severe haemorrhage and skeletal abnormalities. Both radii are absent, the ulnae are shortened and the knees are dysplastic. However, the patients have five digits in the hands, as opposed to the absence of the thumb in persons with Fanconi's anaemia.
ULTRASOUND Messages For November, 1998: TAR Syndrome tar syndrome. From Arduini (Arduini@med.UniRoma2.It) Mon Nov 23 085131 1998.Messages sorted by date thread subject author ; Next message http://forums.obgyn.net/ultrasound/ULTRASOUND.9811/0107.html
Extractions: Mon Nov 23 08:51:31 1998 Dear colleagues, I am involved like expert by the Court for a problem of a missed diagnosis in pregnancy. At birth the neonate shows a bilateral radial aplasia, and a thrombocytopenia, configuring the clinical picture of a TAR syndrome. The mother had a low-risk pregnancy and negative US scan at 21 wks. It is possible to visualize this aplasia and there are some minimum standards in different nations in the world for an exam at this week of gestation? In Italy we have only a suggestion by Italian Society of US in Ob/Gyn. Prof. Domenico Arduini ********************************** Prof. Domenico Arduini
ULTRASOUND Messages For November, 1998: Re: TAR Syndrome Re tar syndrome. From Arduini (Arduini@med.UniRoma2.It) Tue Nov 24 102303 1998.Messages sorted by date thread subject author http://forums.obgyn.net/ultrasound/ULTRASOUND.9811/0127.html
Extractions: ********************************** Prof. Domenico Arduini ********************************** Prenatal Medicine Department University of Rome "Tor Vergata" Fax. +39 6 3630 9421 ********************************** Next message: DuBose, Terry: "Re: TAR syndrome" Previous message: James S Smeltzer MD: "Re: cyberdocs" In reply to: Joseph A Worrall: "Re: TAR syndrome" Next in thread: art fougner, md: "Re: TAR syndrome"
Thrombocytopenia-Absent Radius (TAR) Syndrome Thrombocytopenia Absent Radius Syndrome (TAR) Daughter with tar syndrome, Gtube feeds, and Central line feedings and dislocated hips Prenatal diagnosis http://www.bdid.com/tar.htm
TAR Syndrome - General Practice Notebook tar syndrome. This syndrome consists of radial aplasia or hypoplasia and The major cardiovascular manifestations of this syndrome are atrial septal http://www.gpnotebook.co.uk/cache/-670695402.htm
Extractions: The TAR (thrombocytopenia absent radius) syndrome is a rare genetic disorder that follows an autosomal recessive pattern of inheritance. It is to be distinguished from the Fanconi variants. Several types of limb deficits are associated with this syndrome. The Area Child Amputee Center has been involved in the evaluation and care of six children with this syndrome. Patients tend to have a rather typical bilateral intercalary radial hemimelia. The marked foreshortening in the upper extremities make them the clinical homologues of an upper total phocomelia. They also tend to have lower-limb anomalies, which consist primarily of a marked genu varum. The deformity is accompanied by a variety of roentgenographic manifestations. Upper- and lower-limb problems are addressed as regards clinical presentation and prosthetic/orthotic management. *Area Child Amputee Center, 235 Wealthy SE, Grand Rapids, MI 49503
Tar Syndrome - Talk Medical Humanfriendly medical definition of tar syndrome. http://www.talkmedical.com/medical-dictionary/14045/Tar-Syndrome
Extractions: Tell a friend TAR syndrome: TAR stands for Thrombocytopenia (low blood platelets) and Aplasia (absence) of the Radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the TAR child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome. Print this page About Talk Medical Help Contact Us ... Terms and Conditions
Extractions: Vol. 138 No. 4, April 1984 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager Articles in PubMed by Adeyokunnu AA Contact me when this article is cited A. A. Adeyokunnu Five patients with radial aplasia studied during a period of ten years at the University College Hospital, Ibadan, Nigeria, had the amegakaryocytic thrombocytopenia syndrome. Together, they are termed the TAR syndrome. Two of the five patients were siblings from a polygamous family; three patients had relative hypogammaglobulinemia, and one of these patients had late onset of congenital varicella. The findings in these five cases led to
Surgery Door - Support Groups The tar syndrome Support Group is a small, parentled group with limited funds . To offer support to families affected by tar syndrome. http://www.surgerydoor.co.uk/sg/detail.asp?Recno=26739613
Journal Of Pediatric Hematology Oncology - UserLogin The deaths from tar syndrome are usually sequelae of massive bleeding or This article reports yet another infant with tar syndrome in whom acute myeloid http://www.jpho-online.com/pt/re/jpho/fulltext.00043426-200202000-00015.htm
Extractions: Purpose: The pathogenesis of thrombocytopenia in patients with thrombocytopenia with absent radii (TAR) syndrome has not been clarified yet. Patients and Methods: This is the first report of a Japanese patient with TAR syndrome. We studied his megakaryopoiesis in vitro and serum levels of thrombopoietin (TPO). Results: Serum levels of TPO in the patient with TAR syndrome were comparable with those of an age-matched control. The bone marrow cells from the patient with TAR syndrome actually generated megakaryocyte colonies in the presence of TPO and the numbers were significantly greater than those from the age-matched control marrow. However, megakaryocyte colonies from the marrow cells with TAR syndrome contained a much lower number of cells per colony and the size of the individual megakaryocytes appeared to be smaller. Conclusion: These data suggest that megakaryocyte progenitors from patients with TAR syndrome may have decreased proliferative and differentiative capacity to respond to TPO, leading to thrombocytopenia.
%274000 THROMBOCYTOPENIAABSENT RADIUS SYNDROME Cow s milk intolerance is said to occur frequently in the tar syndrome (Whitfield Clefting must be rare in tar syndrome. Abnormalities in the legs are http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:274000] -e
268300 ROBERTS SYNDROME; RBS (1978) suggested that the SC phocomelia syndrome and the tar syndrome (274000)are not separate from the Roberts syndrome. Tomkins et al. http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:268300] -e
