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Stiff-person Syndrome:     more detail

The Official Patient's Sourcebook on Stiff-Person Syndrome: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-10-10 Stiff Person Syndrome Stiff person syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Bruno Azevedo, Iuri, MD, PhD Louro, 2005 Rare disease may offer clues to MS. (Moersch-Woltman syndrome): An article from: Inside MS by Phyllis Shaw, 1989-06-22

lists with details

1. Stiff-Person Syndrome
   An article about stiffperson syndrome, a rare progressive neurological disorder.  
   http://healthlink.mcw.edu/article/921988627.html
   
   Extractions: Subscribe now >> Stiff-person syndrome is a rare progressive neurological disorder characterized by constant painful contractions and spasms of voluntary muscles, particularly the muscles of the back and upper legs. Symptoms may occur gradually, spreading from the back and legs to involve the arms and neck. Symptoms may worsen when the affected individual is anxious or exposed to sudden motion or noise. Affected muscles may become twisted and contracted, resulting in bone fractures in the most severe cases. Individuals with stiff-person syndrome may have difficulty making sudden movements and may have a stiff-legged, unsteady gait. Sleep usually suppresses frequency of contractions. Stiffness may increase and patients may develop a hunched posture (kyphosis) or a swayback (lordosis). Researchers theorize that stiff-person syndrome may be an autoimmune disorder. Other autoimmune disorders such as diabetes, pernicious anemia (a chronic, progressive blood disorder), and thyroiditis (inflammation of the thyroid gland) may occur more frequently in patients with stiff-person syndrome.

2. NINDS Forwarding Page
   Information sheet compiled by National Institute of Neurological Disorders and Stroke.  
   http://www.ninds.nih.gov/health_and_medical/disorders/stiffperson_doc.htm
   
   Extractions: NINDS has redesigned its website and the URL for the page you were seeking has changed. The new URL for this page is /disorders/stiffperson/stiffperson.htm . Please update your bookmark to this page. You will be automatically taken to this page in 5 seconds, or you can click the link to go there now.

3. Stiff-Person Syndrome Information Page National Institute Of
   Stiffperson (stiff-man syndrome) information sheet compiled by NINDS.  
   http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Stiff-Person Syndrome
   An article about stiffperson syndrome, a rare progressive neurological disorder.  
   http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Stiff-Person Syndrome Information Page: National Institute Of Neurological Disor
   Stiffperson (stiff-man syndrome) information sheet compiled by NINDS.  
   http://www.ninds.nih.gov/disorders/stiffperson/stiffperson.htm
   
   Extractions: The drug diazepam, which relaxes the muscles, provides improvement in most cases. Baclofen, phenytoin, clonidine, or tizanidine may provide additional benefit. In some patients, immunomodulatory treatments such as intravenous immunoglobulin may be beneficial. Physical and rehabilitation therapy may also be needed. What is the prognosis?

6. The Stiff-Person Syndrome An Autoimmune Disorder Affecting
   The stiffperson syndrome An Autoimmune Disorder Affecting Neurotransmission of -Aminobutyric Acid Lucien M. Levy, MD, PhD, Moderator  
   http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. Stiff-Person Syndrome Press Releases: National Institute Of Neurological Disorde
   Stiffperson (stiff-man syndrome) information sheet compiled by NINDS.  
   http://www.ninds.nih.gov/disorders/stiffperson/press_stiffperson.htm

8. The Stiff-Person Syndrome An Autoimmune Disorder Affecting
   The stiffperson syndrome An Autoimmune Disorder Affecting Neurotransmission of -Aminobutyric Acid Lucien M. Levy, MD, PhD, Moderator  
   http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Introduction: Stiff-Person Syndrome - WrongDiagnosis.com
   Introduction to stiffperson syndrome as a medical condition including symptoms,diagnosis, misdiagnosis, treatment, prevention, and prognosis.  
   http://www.wrongdiagnosis.com/s/stiff_person_syndrome/intro.htm
   
   Extractions: Stiff-Person Syndrome: Stiff-person syndrome is a rare progressive neurological disorder characterized by constant painful contractions and spasms of voluntary muscles, particularly the muscles of the back and upper legs. Researching symptoms of Stiff-Person Syndrome: Further information about the symptoms of Stiff-Person Syndrome is available including a list of symptoms of Stiff-Person Syndrome , or alternatively return to research other symptoms in the symptom center Treatments for Stiff-Person Syndrome: Various information is available about treatments available for Stiff-Person Syndrome current research about Stiff-Person Syndrome treatments , or research treatments for other diseases.

10. Humoral And Cellular Autoimmune Responses In Stiff Person Syndrome
    Humoral and Cellular Autoimmune Responses in Stiff Person Syndrome TOBIAS LOHMANNa , MARCO LONDEIb , MOHAMMED HAWAc and R. DAVID G. LESLIEc  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Article: NINDS Stiff-Person Syndrome Information Page: NINDS - WrongDiagnosis.co
    Medical article NINDS stiffperson syndrome Information Page NINDS including allsymptom, diagnosis, misdiagnosis, treatment and prevention information.  
    http://www.wrongdiagnosis.com/artic/ninds_stiff_person_syndrome_information_page

12. Immunotherapy Treatment Shows Dramatic Results For Rare
    Immunotherapy Treatment Shows Dramatic Results For Rare Neurological Disorder Stiff Person Syndrome  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Stiff Person Syndrome
    stiffperson syndrome is an extremely rare progressive neurological disorder characterized by persistent stiffness (rigidity) and spasms of certain  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Stiff-person Syndrome Research
    Researchers at RuprechtKarls-University in Heidelberg, Germany, investigatedwhether the excitability of neurons in the motor cortex is enhanced in  
    http://rarediseases.about.com/b/a/119474.htm
    
    Extractions: zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a70' About Rare / Orphan Diseases Rare Diseases Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/7.htm','');w(xb+xb); Sign Up Now for the Rare / Orphan Diseases newsletter! Researchers at Ruprecht-Karls-University in Heidelberg, Germany, investigated whether the excitability of neurons in the motor cortex is enhanced in stiff-person syndrome , and if this is related to autoimmunity against glutamic acid decarboxylase (GAD). They compared 21 individuals with stiff-person syndrome with 14 age-matched controls using testing of motor neuron excitability. They also examined the levels of anti-GAD antibodies in the blood and cerebrospinal fluid. The findings suggested that motor neuron hyperexcitability in stiff-person syndrome is related to anti-GAD autoimmunity. The research was published in the April 2004 issue of Neurology Email to a Friend Display Latest Headlines Read Archives powered by Movable Type Advertisement Most Popular Muscular Dystrophy ALD and Lorenzo's Oil Progeria Syndromes Leprosy (Hansen's Disease) ... The Elephant Man What's Hot Charcot-Marie-Tooth Disease Peyronie's Disease Twin-to-Twin Transfusion Synd Autoimmune Kidney Disease ... Cri-du-Chat Syndrome adunitCM(150,100,'x55')

15. Arch Neurol Abstract Stiff-Person Syndrome Following West Nile
    Neuropathology Collection Email Alerts stiff-person syndrome Following West Nile Fever Sharon Hassin-Baer, MD ; Eilon D. Kirson, MD, PhD  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Stiff-Person Syndrome
    stiffperson syndrome stiff-person syndrome is a rare progressive neurological Individuals with stiff-person syndrome may have difficulty making  
    http://www.health-nexus.com/stiff-person_syndrome1.htm
    
    Extractions: The #1 Health information site Health-Nexus.Net Health-Nexus.Org Home ... Up Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Stiff-Person Syndrome Stiff Person Syndrome Sites Web sites devoted to health, nutrition, and fitness. ... Most of the links below are direct links to pages on stiff person syndrome (SPS, a.k.a. ...

17. Clinical Study 02-N-0122, Natural History And Immunopathogenesis Of
    MR Spectroscopy GAD Recruitment Keyword(s) Stiff Person Syndrome SPS Condition(s) stiffperson syndrome Investigational Drug(s)  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Stiff Person Syndrome And Anesthesia Case Report Bouw Et Al. 97
    Stiff Person Syndrome and Anesthesia Case Report Jans Bouw, MD* , Karin Leendertse, MD* , Marina A. J. Tijssen, MD PhD , and  
    http://tmsyn.an.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Clinical Trial: Cause, Development, And Progression Of Stiff-Person Syndrome
    stiffperson syndrome (SPS) is a progressive neurological disorder characterized by The stiff-person syndrome an autoimmune disorder affecting  
    http://www.clinicaltrials.gov/ct/show/NCT00030940
    
    Extractions: Verified by National Institutes of Health Clinical Center (CC) February 3, 2005 Sponsored by: National Institute of Neurological Disorders and Stroke (NINDS) Information provided by: National Institutes of Health Clinical Center (CC) ClinicalTrials.gov Identifier: Purpose This study will explore the role of various immune factors involved in producing the disease symptoms in stiff-person syndrome (SPS) and follow disease progression in patients. SPS is a progressive disease in which unexpected noises, touches or stressful events set off muscle spasms and stiffness. It is thought to be an autoimmune disease in which the body produces antibodies that attack certain healthy tissues. A better understanding of the disease may help researchers design new therapies. Patients of any age with SPS may be eligible for this study, except those who: - Lack of serum anti-GAD antibodies - Have very advanced disease that precludes traveling - Have severe cardiovascular, renal, or other end-organ-disease states

20. Neurology -- Sign In Page
    GAD antibodies in stiffperson syndrome Fujii M, Li M, Lutfi B, Kyhos J,McElroy B. High dose intravenous immune globulin for stiff-person syndrome.  
    http://www.neurology.org/cgi/content/full/63/11/1999
    
    Extractions: Submit a response ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Chang, T. Articles by Lang, B. Related Collections Stiff person syndrome

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