NORD - National Organization For Rare Disorders, Inc. Continuous Muscle Fiber Activity Syndrome; Isaacs Syndrome; IsaacsMerten Syndrome;quantal squander. Disorder Subdivisions. General Discussion http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Neuromyotonia
Extractions: A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491) Synonyms and Source Vocabularies:
Penn State Faculty Research Expertise Database (FRED) Pseudomyotonia Syndrome of Isaacs, quantal squander. Syndrome of Continuous MuscleActivity, Continuous Myokymia. Continuous Myokymias, Gamstorp Wohlfart http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D020386
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References 1 - 1040 Isaacs, H., quantal squander, SAJ Lab. Clin. Med., 10 9395, 1964. 178. Itil,TM, Rizzo, AE, and Shapiro, DM, Study of behavior and EEG correlation during http://www.remarkablemedicine.com/Clinical/0001-1040.html
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