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Pseudoxanthoma Elasticum:     more detail

Gale Encyclopedia of Medicine: Pseudoxanthoma elasticum by Barbara J. Pettersen, 2002-01-01 Pseudoxanthoma elasticum: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Barbara, MS, CGC Pettersen, 2005 Novel mutations in the ABCC6 Gene of German Patients with pseudoxanthoma elasticum.: An article from: Human Biology by Veronika Schulz, Doris Hendig, et all 2005-06-01 Pseudoxanthoma Elasticum: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Barbara Pettersen, 2006 Pseudoxanthoma Elasticum - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker, 2007-07-18 Pseudoxanthoma elasticum (Clinics in dermatology) by Kenneth H Neldner, 1988 Vascular studies in pseudoxanthoma elasticum and angioid streaks,: With a series of color photographs of the eyeground lesions (Acta medica Scandinavica. Supplementum) by Uno Carlborg, 1959

lists with details

1. NORD - National Organization For Rare Disorders, Inc.
   Offers a general discussion and resources for PXE.  
   http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Pseudoxanthom

2. PiXiE Supporting Sufferers Of Pseudoxanthoma Elasticum
   Organisation supports sufferers of pseudoxanthoma elasticum (PXE). Includes information about the condition and its causes, guidance on managing it, and contact details.  
   http://www.pxe.org.uk/
   
   Extractions: pxeeurope@aol.com Click The PXE Files Magazine To view the magazine you must have Adobe Acrobat Reader installed. If you have, just click on image. Elspeth Lax founded PiXiE in 1984 to support PXE sufferers and their families. Since then, she has become actively involved in promoting research into the disease and raising awareness among the medical community. Elspeth and her father with former President George Bush I was diagnosed as having PXE when I was 23 at my local hospital. However, when I was 26 I went for a second opinion and was told I would be blind by the time I was 40, my stomach would split open if I got pregnant and I had to leave the police force as it would be too dangerous a career in which to remain in case of head injury, in which case I could lose my vision straight away. Having felt suicidal, I wasn't going to let others with PXE suffer the same way I had.

3. Pseudoxanthoma Elasticum (PXE) / The Family Village Library
   pseudoxanthoma elasticum (PXE)  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. PXE Links
   Angioid Streaks and pseudoxanthoma elasticumhttp//www.vrmny. com/angioid_streaks_and_pxe.htm This site provides information written by physicians about  
   http://www.pxe.org/links.html
   
   Extractions: Online Mendelian Inheritance in Man (PXE entry): http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?264800 Online Mendelian Inheritance in Man (OMIM) is a database of human genes and genetic disorders written and maintained by medical professionals at Johns Hopkins and elsewhere, and developed for the Internet by the National Center for Biotechnology Information (NCBI). The information on this site is geared toward medical professionals.

5. PXE International
   The comprehensive source for pseudoxanthoma elasticum research and world wide activities.  
   http://pxe.org

6. Angioid Streaks And Pseudoxanthoma Elasticum
   Information regarding angioid streaks and pseudoxanthoma elasticum  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. NAPE, Inc.
   committed to the support for people who have pseudoxanthoma elasticum (PXE). pseudoxanthoma elasticum, is an inherited disorder that affects the skin,  
   http://www.pxenape.org/
   
   Extractions: Nape is an organization committed to the support for people who have Pseudoxanthoma Elasticum (PXE). Pseudoxanthoma Elasticum, is an inherited disorder that affects the skin, the retina of the eyes and the cardiovascular system. NAPE is headquartered in St. Louis, Missouri. Everyone with PXE and those with an interest in PXE are encouraged to join this organization. Click here for more information. Basic PXE Information PXE was first described about 100 years ago. Initially it was believed to involve only the skin. The skin changes were thought to be cholesterol deposits called xanthomas that can occur in the skin of individuals with high blood cholesterol levels...

8. PXE International
   One Paycheck at a Time, Inc. to donate 10% of its 2005 net income to PXE International in the hopes of finding a cure.  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. EMedicine - Pseudoxanthoma Elasticum : Article By L Frank Glass, MD
   pseudoxanthoma elasticum pseudoxanthoma elasticum (PXE) is an inherited connective tissue disorder characterized by progressive calcification and  
   http://www.emedicine.com/DERM/topic359.htm
   
   Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Diseases Of The Dermis Last Updated: July 24, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: PXE, connective tissue disorder, calcification and fragmentation of elastic fibers AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: L Frank Glass, MD , Chief of Dermatopathology, Associate Professor, Departments of Internal Medicine and Pathology, University of South Florida College of Medicine Coauthor(s): Daniel F Smith, MD , Staff Physician, Department of Internal Medicine, Division of Dermatology and Cutaneous Surgery, University of South Florida School of Medicine; Anu Gupta, MD , Staff Physician, Department of Internal Medicine, Division of Dermatology and Cutaneous Surgery, University of South Florida School of Medicine L Frank Glass, MD, is a member of the following medical societies:

10. Pseudoxanthoma Elasticum | Vhi Healthcare
    A definition of pseudoxanthoma elasticum followed by a description, causes and symptoms, diagnosis, treatment options, prognosis and prevention.  
    http://www2.vhi.ie/topic/topic100587360
    
    Extractions: document.write(""); About Us Contact Us Downloads Site Map ... Members Healthy Living: Health A-Z Irish Health News Alternative Travel Health ... Quit Smoking Life Stages: Baby Children Student Women ... Senior Contact Us Ask The Experts Ask The Nurse Enquiry Phone ... Address Pseudoxanthoma elasticum Barbara J. Pettersen Below: The course of PXE varies greatly between individuals. Typically it is first noticed during adolescence as yellow-orange bumps on the side of the neck. Similar bumps may appear at other places where the skin bends a lot, like the backs of the knees and the insides of the elbows. The skin in these areas tends to get thick, leathery, inelastic, and acquire extra folds. These skin problems have no serious consequences, and for some people, the disease progresses no further. Bruch's membrane, a layer of elastic fibers in front of the retina, becomes calcified in some people with PXE. Calcification causes cracks in Bruch's membrane, which can be seen through an ophthalmoscope as red, brown, or gray streaks called angioid streaks. The cracks can eventually (e.g., in 10-20 years) cause bleeding, and the usual resultant scarring leads to central vision deterioration. However, peripheral vision is unaffected.

11. EMedicine - Pseudoxanthoma Elasticum Article By L Frank Glass, MD
    pseudoxanthoma elasticum pseudoxanthoma elasticum (PXE) is an inherited connective tissue disorder characterized by progressive calcification and  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. EMedicine - Pseudoxanthoma Elasticum : Article By Diego Calonje, MD
    pseudoxanthoma elasticum pseudoxanthoma elasticum (PXE) is an inherited systemic disease characterized by changes in the elastic tissue of the skin.  
    http://www.emedicine.com/oph/topic475.htm
    
    Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Ophthalmology Connective Tissue Disorders Last Updated: June 7, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Diego Calonje, MD , Consulting Staff, Department of Ophthalmology, Private Practice Coauthor(s): Sherif M El-Harazi, MD, MPH , Consulting Staff, Department of Ophthalmology, Sherif El-Harazi, MD Editor(s): Vytautas A Pakainis, MD , Chief of Ophthalmology, Dorn Veterans Administration Medical Center, Professor of Ophthalmology, Ophthalmology, University of South Carolina School of Medicine; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, eMedicine; Steve Charles, MD , Director of Charles Retina Institute; Clinical Professor, Department of Ophthalmology, University of Tennessee College of Medicine; Lance L Brown, OD, MD

13. Pseudoxanthoma Elasticum
    pseudoxanthoma elasticum a rare cause of gastrointestinal bleeding. Spinzi G, Strocchi E, Imperiali G, Sangiovanni A, Terruzzi V, Minoli G.  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Pseudoxanthoma Elasticum - Genetics Home Reference
    Where can I find additional information about pseudoxanthoma elasticum? What other names do people use for pseudoxanthoma elasticum?  
    http://ghr.nlm.nih.gov/condition=pseudoxanthomaelasticum
    
    Extractions: Home What's New Browse Handbook ... Search Pseudoxanthoma elasticum On this page: Pseudoxanthoma elasticum is a progressive disorder that affects connective tissue, the material that supports and holds together different structures of the body. This condition is characterized by accumulated deposits of calcium (calcification) and other minerals in elastic fibers, a component of connective tissue. Calcification can affect elastic fibers in the skin, eyes, and blood vessels, and less frequently in other areas such as the digestive tract. As a result, people with pseudoxanthoma elasticum may have yellowish bumps (papules) on their necks, underarms, and elsewhere on the skin. They may also have changes in the eye called angioid streaks that can lead to vision loss if bleeding occurs. People with pseudoxanthoma elasticum are also at increased risk for problems involving blood vessels, such as decreased blood flow to the arms and legs, which may cause cramping or pain with exercise (claudication). Bleeding in the digestive tract is another risk. Most affected individuals live a normal lifespan.

15. Pseudoxanthoma Elasticum
    pseudoxanthoma elasticum (PXE) An excellent resource for information on PXE or the ocular side effect of Angioid Streaks.  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Pseudoxanthoma Elasticum - Glossary Entry - Genetics Home Reference
    pseudoxanthoma elasticum. Synonym(s). elastorrhexis, systemic, of Touraine; elastosis dystrophica syndrome. Definition(s). A chronic degenerative disease of  
    http://ghr.nlm.nih.gov/ghr/glossary/pseudoxanthomaelasticum

17. PiXiE Supporting Sufferers Of Pseudoxanthoma Elasticum
    Organisation supports sufferers of pseudoxanthoma elasticum (PXE). Includes information about the condition and its causes, guidance on managing it  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Pseudoxanthoma Elasticum - Arthritis And Arthritic Conditions, Medications, And
    Explains arthritis conditions includes symptoms, causes, medications, and treatment. Written and reviewed by a Rheumatologist.  
    http://www.medicinenet.com/pseudoxanthoma_elasticum/article.htm
    
    Extractions: The connective tissues are the structural portions of the body that essentially hold the body cells together. These tissues form a framework or matrix for the body. The connective tissues are composed of 2 major structural molecules, collagen and elastin. There are many different collagen protein types which vary in abundance depending on body area. Elastin is another protein which has the capability of stretching and returning to original length like a spring. Pseudoxanthoma elasticum (PXE) is a rare disorder of degeneration of the elastic fibers with tiny areas of calcification in the skin, back of the eyes (retinae), and blood vessels. Interestingly, while elastin is the major component of ligaments (tissues which attach bone to bone), the ligaments are not apparently affected by PXE. How is pseudoxanthoma elasticum inherited?

19. NAPE, Inc.
    Nape is an organization committed to the support for people who have pseudoxanthoma elasticum (PXE). pseudoxanthoma elasticum, is an inherited  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. Elastic Tissue Abnormalities Resembling Pseudoxanthoma Elasticum
    Elastic tissue abnormalities resembling pseudoxanthoma elasticum in thalassemia and the sickling syndromes Athanasios Aessopos  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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