Geometry.Net - Health_Conditions: Pemphigus

The IPF Has MOVED!
Includes information about the condition, the organisation, plus support groups.
http://www.pemphigus.org/
Pemphigus Research
Information on this autoimmune blistering disease by the department of dermatology of the John Hopkins university.
http://www.hopkinsmedicine.org/pemphigus/
PEMPHIGUS VULGARIS :
An article explaining the seriousness of the condition.
http://www.chronicillnet.org/online/lehne.html

Extractions: OLNews@aol.com Return to the OnLine News Index If you haven't heard of it before, don't feel bad most people haven't. But if you or someone you love has it, the symptoms are unforgettable. "It" is Pemphigus Vulgaris. Its abrasive name draws a fitting mental picture of what it does to its victims . Pemphigus, or commonly referred to as "PV", is an auto-immune blistering disorder of the skin and mucous membranes where those afflicted suffer from burn-like lesions all over their bodies. The sores may never heal in some cases or may not heal for extended periods of time. Some patients can coexist with the disease for years, while others will die a slow and complicated death. Janet Lehne has it. "Sometimes I feel like I'm a walking open sore, and believe it or not, I actually have a mild case." When she first realized something was wrong in 1983, she thought she was dying from AIDS. The common lesions now known to be associated with AIDS and HIV are very similar to a PV outbreak. "My doctors, in the early eighties, were convinced that I was symptomatic and suffering from an aggressive case of AIDS. It scared the hell out of me. I thought I was a dead person." But then she was told she had one of those unusually rare skin conditions that no one really knew much about. "What is PV?" would be one of the obscure, extra-credit questions for medical students of dermatology. She says her scalp literally tears. Her gums bleed and blister before disintegrating. Janet says PV is usually recognized by its slow-progression of infections in the mouth.
Pemphigus
Background information, traditional treatments and natural medicine, plus the author s personal account.
http://www.uoregon.edu/~sshapiro/Pemphigus/TableOfContents.html

Extractions: Pemphigus Update April, 2003 : It has now been over four years since I last took Prednisone or any other medical treatment for pemphigus. I have been choosing my foods according to my blood type for about 5 and 1/2 years. When I was first diagnosed in 1995, I set a goal to be Pemphigus free by 2003 (seven years). In February, 2003, pemphigus was officially removed from my medical chart by my primary care physician. OK, it officially took eight years, but I was diagnosed in December, so I think that's close enough? What I have found that works for me should produce repeatable results, meaning that others who try it should experience the same results. It doesn't cost anything, there are no products, potions or lotions to purchase. It's all completely free. The choice is yours.
PPS: Articles About Pemphigus And Pemphigoid From The Pemphigus & Pemphigoid Soc
Find information about PPS, publications, an online support group, articles and a medical glossary.
http://www.1clever.org/

Extractions: Text only provides emotional support and on-going education about treatments, medications and recovery strategies, so patients may regain control of their lives as soon as possible. We work to bring greater awareness to the public and medical community about these rare autoimmune skin diseases. Because the PPS is an all-volunteer foundation, 100% of your donations go toward these goals. Donation Information How to donate Our wish list Got time? Become a Mentor Shopping partners How to join the PPS Pemphigoid Bullous pemphigoid (BP) cicatricial pemphigoid (CP) mucous membrane pemphigoid (MMP) ocular pemphigoid (OC) ... Frequently asked questions about pemphigoid pemphigoid gestationis Pemphigus Pemphigus vulgaris (PV) pemphigus foliaceus (PF) fogo selvagem (FS) ... Pemphigus in animals Medications and side effects Medications used to treat pemphigus and pemphigoid including side effects
Pemphigus Vulgaire
Fiches dinformations pratiques sur le pemphigus vulgaire, autres sites internet, types de consultations adaptÃ©es, laboratoires de diagnostic, projets de recherche en cours, associations de patients et mÃ©dicaments.
http://www.orpha.net/static/FR/pemphigus_vulgaire.html

Extractions: Le pemphigus est un groupe de maladies chroniques de la peau d'origine autoimmune caractérisées par la formation de vésicules dans la couche superficielle de la peau et des muqueuses. La maladie affecte d'abord la bouche et la peau du crâne. Les vésicules sont de consistance molle et se rompent facilement. L'oesophage, le rectum, le nez ou les paupières peuvent être également atteints. Cette affection touche préférentiellement les adultes d'origine juive ou méditerranéenne. Le pemphigus vulgaire est une maladie parfois fatale, caractérisée sur le plan immunohistologique par des dépôts d'immunoglobine IgG et l'activation du complément à la surface des kératinocytes. L'activation du complément a été impliquée dans la pathogenèse, avec présence de dépôts de C3 dans 90 % des cas. Le traitement repose sur la corticothérapie générale avec ou sans immunosuppresseurs. *Auteur : Equipe Editoriale d'Orphanet (septembre 2002)*. Mise à jour : 04/09/2005 Accès à la base de données Orphanet
International Pemphigus Foundation
International pemphigus Foundation ? 1540 River Park Drive, Suite 208 ? Sacramento, CA 95815 Phone 916922-1298 ? Fax 916-922-1258
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
About Pemphigus - International Pemphigus Foundation
The International pemphigus Foundation provides information about the autoimmune skin disorders known as pemphigus and pemphigoid while also offering advice
http://www.pemphigus.org/whatisgus.html

Extractions: What is Pemphigus? Pemphigus is a group of rare autoimmune blistering diseases of the skin and/or mucous membranes. Pemphigus is not contagious - not even blood to blood. Our immune system produces antibodies that normally attack hostile viruses and bacteria in an effort to keep us healthy. In a person with pemphigus, however, the immune system mistakenly perceives the cells in skin and/or mucous membrane as foreign, and attacks them. Antibodies that attack one's own cells are called autoantibodies. The part of the cells that are attacked in pemphigus are proteins called desmogleins. Desmogleins form the glue that attaches adjacent skin cells, keeping the skin intact. When autoantibodies attack desmogleins, the cells become separated from each other. The skin virtually becomes unglued. This causes burn-like lesions or blisters that do not heal. In some cases, these blisters can cover a significant area of the skin. There are several types of Pemphigus , and early diagnosis is important. Though there may be a genetic predisposition and some groups with a higher incidence of the disease, the disease appears to affect people across racial and cultural lines, so it's not possible to say
Pemphigus.com: Information On Types Of Pemphigus, Vulagris, Foliaceus, Paraneopl
Information on the types and treatments.
http://www.pemphigus.com

Extractions: Pemphigus describes a blistering condition of the skin caused by the attack of antibodies of certain proteins on the surface of skin cells. This attack interferes with the ability of the skin cells to bind to each other. The immune system normally functions to protect us against foreign invaders, but when it erroneously attacks a component of "self" an autoimmune disease can occur. (Other autoimmune disease include rheumatoid arthritis, lupus, multiple sclerosis and myasthenia gravis) Pemphigus vulgaris (PV) is the most common form. It is a relatively rare disease, affecting approximately 1 in 100,000 people. The lesions commonly manifest in people from 40 to 60 years of age. PV usually begins as blisters in the mouth. Inflammation or erosions may also be present in the lining of the eye and eyelids, and the membranes of the nose or genital tract. Half of the patients also develop blisters or erosions of the skin, often in the groin, underarm, face, scalp and chest areas. The lesions can cover extensive portions of the body. When the blisters or bullae rupture they leave red erosions surrounded by a crust and scaling skin.
About Pemphigus - International Pemphigus Foundation
The International pemphigus Foundation provides information about the autoimmune skin disorders known as pemphigus and pemphigoid while also offering
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Pemphigus Vulgaris Network
Website of the pemphigus Vulgaris Network, the United Kingdom support group for people living with pemphigus and Mucous Membrane Pemphigoid.
http://www.pemphigus.org.uk/

Extractions: Welcome to the website of the Pemphigus Vulgaris Network, the United Kingdom support group for people living with Pemphigus and Mucous Membrane Pemphigoid. This page includes the following sections: What is Pemphigus Vulgaris? What is the PV Network? How is PV diagnosed? How is it treated? ... Clinical Trial in the UK Pemphigus Vulgaris (PV) is one of a group of rare, relapsing auto-immune diseases causing blistering of the skin and mucous membranes (eg mouth, nose, throat and genitals). In pemphigus disorders the immune system makes a mistake, views cells in the skin and mucous membranes as foreign and an immune response is triggered. Affected individuals have high concentrations of antibodies produced by the immune system. These bind to a specific protein in the skin (desmoglein 3 and sometimes desmoglein 1), causing interference with the skins normal function. The cells no longer stick together and become separated from each other. This causes the burn-like lesions or blisters that are typical of PV. Symptoms often occur first in the mouth, but lesions can cover a significant area of skin. The disease is non-infectious. Although it is known that desmoglein antibodies cause PV, it is not known why people develop these autoantibodies in the first place. Genetic factors are believed to be important but it is likely that there are other factors which help trigger PV.
Immune Problems - Pemphigus
pemphigus pemphigus pemphiguscysts on feet pemphigus treatment pemphigus in Saluki also see Immune Problems also see Skin Problems
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
File Not Found - British Association Of Dermatologists
British Association of Dermatologists information sheet describing the symptoms and management of this inherited skin condition.
http://www.bad.org.uk/patients/skin_disorders/hailey/
Pemphigus Vulgaris FAQ
pemphigus Vulgaris is a rare autoimmunedisease of skin. This FAQ is written for patients and their families.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
PEMPHIGUS VULGARIS
pemphigus VULGARIS A Diagnostic Chameleon ?
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Pemphigus Research
The Johns Hopkins Laboratory For Translational Research in pemphigus TYPES OF pemphigus pemphigus Vulgaris pemphigus is a term used to describe blistering
http://www.hopkinsmedicine.org/pemphigus/types.html

Extractions: Pemphigus is a term used to describe blistering of the skin caused by binding of antibodies to the surface of the cells of the outer layer of the skin, the epidermis. In pemphigus vulgaris, the most common form of pemphigus, there are IgG antibodies that bind to the cell surfaces of epidermis of the skin as well as the epithelium lining mucosal surfaces such as the mouth. As a result, patients develop severe oral ulcerations, and may also have inflammation or erosions of the lining of the eye and eyelids (conjunctiva), the nasal mucosa, or the genital mucosa. Half of the patients also develop blisters or erosions of the skin, often in the head and neck area. Diagnosis is made by biopsying the skin or oral mucosa. The biopsy specimens show deposition of antibodies on the cell surfaces of the epidermis or epithelium by using specialized immunofluorescence techniques performed in our Dermatoimmunology Laboratory. Our laboratory also uses immunofluorescence techniques to detect antibodies in the blood. The titer of these antibodies may be helpful in evaluating the severity of the disease as well as disease course and response to therapy. Without treatment, the mortality of pemphigus vulgaris approaches 100%. The current mortality rate still ranges from 5 to 25 %. However, this still high mortality rate is due to the use of unjustified massive doses of prednisone ( more than 80 mg/kg/day)
Disease Category Listing (617) Pemphigus Vulgaris (PV)
CenterWatch Listing of Clinical Research Trials for pemphigus Vulgaris (PV)
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
PEMPHIGUS VULGARIS UPDATE ON ETIOPATHOGENESIS, ORAL
pemphigus VULGARIS UPDATE ON ETIOPATHOGENESIS, ORAL MANIFESTATIONS, AND MANAGEMENT Crispian Scully1 * Stephen J. Challacombe2
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Pemphigus - Definition
pemphigus is an autoimmune skin disorder characterized by blistering of the skin and mucous The definition given by de Sauvages to pemphigus maior,
http://www.uoregon.edu/~sshapiro/Pemphigus/DefinePemphigusAndAutoImmuneDisease.h

Extractions: Pemphigus and Autoimmune Disease Pictures Summarized Definition of Pemphigus Development of the Term Pemphigus Similarities to other diseases ... Home Pictures top Dermatology Department: University of Iowa Dermatology Online Atlas Full Body ... Before and After Summarized Definition of Pemphigus top Pemphigus is an autoimmune skin disorder characterized by blistering of the skin and mucous membrane. There are several types of Pemphigus, notably Pemphigus Vulgaris (PV), Pemphigus Foliaceous (PF) and Pemphigus Vegetans (Pvs). Pemphigus is Latin for "Blistering Skin." Pemphigus involves blistering of the outer (epidermal) layer of the skin and mucous membrane. It is an autoimmune disorder where the immune system produces antibodies against specific proteins in the skin and mucous membrane. These antibodies produce a reaction that leads to a separation of epidermal cells (acantholysis). The exact cause of the development of antibodies against the body's own tissues (autoantibodies) is unknown. A few cases have occurred from reactions to medications, including penicillamine and captopril. More than 95% of people with pemphigus have specific HLA antigens. Pemphigus is rare. It occurs almost exclusively in middle-aged or older people, of all races and ethnic groups. About one-half of the cases of pemphigus vulgaris begin with blisters in the mouth, followed by skin blisters. The blisters (bullae) are relatively asymptomatic, but the lesions become widespread and complications develop rapidly and may be debilitating or fatal.
Pemphigus Vulgaris Network
Website of the pemphigus Vulgaris Network, the United Kingdom support group for people living with pemphigus and Mucous Membrane Pemphigoid.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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