Olivopontocerebellar Atrophy - Wikipedia, The Free Encyclopedia olivopontocerebellar atrophy of neonatal onset and Two brothers presented with olivopontocerebellar atrophy of neonatal onset.The clinical features (failure to thrive, hypotonia, liver disease, effusions, http://en.wikipedia.org/wiki/Olivopontocerebellar_atrophy
Extractions: You did it! Over US$240,000 was donated in the 21 day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Olivopontocerebellar atrophy Olivopontocerebellar atrophy (OPCA) are a group of diseases characterized by neuronal degeneration in the cerebellum , pontine nuclei, and inferior olive. They are also referred to as spinocerebellar atrophies or ataxias SCA ). Some also involve brain stem motor nuclei and/or cerebral cortex. All produce gait ataxia, and some also result in tremors, proprioceptive abnormalities, dysarthria , brain stem motor impairment, or dementia. Most are autosomal dominant in inderitance pattern. The primary cause of these hereditary ataxias also appears to be an unstable expansion of the polyglutamine trinucleotide repeat CAG, similar to Huntington's disease edit Olivopontocerebellar atrophy is group of disorders which overlap certain other groups, such as Spinocerebellar ataxia (SCA). Some but not all types of SCA are in the Olivopontocerebellar atrophy group. Some but not all Olivopontocerebellar atrophy conditions, are types of SCA. This situation causes some controversy and confusion about what terms and system of categorization should be used. The subcategories of Olivopontocerebellar atrophy are:
Extractions: Vol Page [Advanced] This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Harding, B. N. Articles by Erdohazi, M. Journal of Neurology, Neurosurgery, and Psychiatry, 1988, Vol 51, 385-390 BN Harding, DB Dunger, DB Grant and M Erdohazi
Extractions: Vol Page [Advanced] This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Rodriguez, M. E. Articles by Obeso, J. A. Journal of Neurology, Neurosurgery, and Psychiatry, 1994, Vol 57, 316-319 ME Rodriguez, J Artieda, JL Zubieta and JA Obeso Clinica Universitaria, University of Navarra, Pamplona, Spain. The presence of reflex myoclonus in response to touching and pin- pricking the wrist or stretching the fingers and to photic stimulation was assessed in 24 patients with a presumed diagnosis of olivopontocerebellar atrophy (OPCA) and in 30 age matched control subjects. Reflex myoclonus to
Extractions: HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Full Text Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager Search for citing articles in: American College of Veterinary Pathologists and L. Poncelet Two otherwise healthy adult cats were presented with progressive cerebellar signs of different severity. Owners requested euthanasia. Necropsy disclosed whole cerebellum and pontine atrophy, with a severity paralleling the neurologic dysfunction. We used cell The severity of the cerebellar cortex atrophy followed a general gradient from the midvermis toward the hemispheres and a local gradient from the depth of the folia toward their tip. Along
Extractions: It is possible that the main title of the report Olivopontocerebellar Atrophy, Hereditary is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Hereditary olivopontocerebellar atrophy (OPCA) is a rare group of disorders characterized by progressive balance problems (disequilibrium), progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia), and difficulty speaking or slurred speech (dysarthria). There are at least five distinct forms of hereditary OPCA. All forms of hereditary OPCA, except one, are inherited as autosomal dominant traits. WE MOVE (Worldwide Education and Awareness for Movement Disorders)
Resource Library Find Information On Olivopontocerebellar Atrophy Find information on olivopontocerebellar atrophy at MerckSource. Learn more aboutolivopontocerebellar atrophy, olivopontocerebellar atrophy is a http://www.mercksource.com/pp/us/cns/cns_hl_adam.jspzQzpgzEzzSzppdocszSzuszSzcns
Multiple System Atrophy Following Chronic Carbon Disulfide Exposure This report describes a case of olivopontocerebellar atrophy, Magnetic resonanceimage showing olivopontocerebellar atrophy in a patient who had been http://ehp.niehs.nih.gov/members/1998/106p611-613frumkin/frumkin-full.html
Extractions: Key words : carbon disulfide, cellulose, environmental diseases, movement disorders, multiple system atrophy, occupational diseases, olivopontocerebellar atrophy, rayon, textiles. Environ Health Perspect 106:611-613 (1998). [Online 18 August 1998]. http://ehpnet1.niehs.nih.gov/docs/1998/106p611-613frumkin/ abstract.html Address correspondence to H. Frumkin, Department of Environmental and Occupational Health, Rollins School of Public Health of Emory University, 1518 Clifton Road, Atlanta, GA 30322 USA. This work was supported in part by NIEHS Environmental/Occupational Medicine Academic Award 5 KO7 ESO0257.
Environ Health Perspect 108-3, 2000: Correspondence However, Frumkin pointed out that olivopontocerebellar atrophy is part of aspectrum of diseases termed multisystem atrophy, which also includes http://ehp.niehs.nih.gov/docs/2000/108-3/correspondence.html
Extractions: Environmental Health Perspectives Volume 108, Number 3, March 2000 Correspondence The September 1998 issue of EHP contained two articles about the neurotoxicity of carbon disulfide. The "NIEHS News" article ( ) reported on a collaborative study that involved scientists from the NIEHS (Research Triangle Park, NC), the U.S. Environmental Protection Agency (Research Triangle Park, NC), the University of North Carolina (Chapel Hill, NC), Duke University (Durham, NC), and Vanderbilt University (Nashville, TN). In this study, the neurotoxicity of carbon disulfide was detailed from the earliest molecular alterations to neurobehavioral findings to electrophysiologic and morphologic changes, and the utility of intramolecular cross-linking in hemoglobin as a biomarker was defined. I was pleased to read this report, and even more pleased to have participated in this study, but I was distressed to see the cover story in the same issue. "Multiple System Atrophy Following Chronic Carbon Disulfide Exposure" ( ), in the "Grand Rounds in Environmental Medicine," is a case report of an individual who developed a degenerative nervous system disease, olivopontocerebellar atrophy, and who had been chronically exposed to carbon disulfide while working for 34 years in a viscose rayon plant in the United States. Frumkin (
Extractions: Vol. 47 No. 2, February 1990 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Bebin EM Perry TL Contact me when this article is cited E. M. Bebin, J. Bebin, R. D. Currier, E. E. Smith and T. L. Perry Department of Pathology, University of Mississippi Medical Center, Jackson. We present a correlation of the morphometric cell density analysis with previous biochemical findings for the inferior olivary nucleus and Purkinje cell layer of the cerebellum from 10 patients (three kindreds) with dominant olivopontocerebellar atrophy. We have analyzed brain amino
Extractions: Vol. 47 No. 9, September 1990 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Berent S Koeppe RA Articles that cite this article Contact me when this article is cited S. Berent, B. Giordani, S. Gilman, L. Junck, S. Lehtinen, D. S. Markel, M. Boivin, K. J. Kluin, R. Parks and R. A. Koeppe Department of Psychiatry, University of Michigan, Ann Arbor. We used standardized neuropsychological measures of intellectual, cognitive, psychomotor, and emotional functioning to compare 39 patients with olivopontocerebellar atrophy and 25 normal controls of similar age. The patients reflected greater depression, anxiety, and subjective
Author Information Key Words Multiple system atrophy, olivopontocerebellar atrophy, Orthostatichypotension, Olivopontocerebellar pathology in multiple system atrophy. http://www.ptjournal.org/May99/May99_abs/v79n5p488.cfm
Extractions: M ultiple system atrophy (MSA) is a neurological disorder that has frequently been misdiagnosed as idiopathic Parkinson disease. A proliferation of articles in recent literature has noted that MSA is a disease that primarily affects the functioning of the autonomic, basal ganglia, and cerebellar systems. The recognition of MSA as a unique entity has emerged gradually during the last century. Quinn, in describing several cases occurring in the late 1800s and early 1900s, may have provided the first descriptions of MSA. In 1925, Bradbury and Eggleston wrote the first clear case report of 3 patients with postural hypotension. Today, we know that postural hypotension is a characteristic sign of MSA. In 1960, Shy and Drager
Other Ataxias MSA with Cerebellar Ataxia Sporadic olivopontocerebellar atrophy (OPCA).NINDS Pamphlet - olivopontocerebellar atrophy (OPCA). January 1997 http://internaf.org/ataxia/othatax.html
Extractions: MSA with Cerebellar Ataxia - "Sporadic Olivopontocerebellar Atrophy" (OPCA): NINDS Pamphlet - Olivopontocerebellar Atrophy (OPCA) January 1997 Movement Disorders: Cerebellar presentation of multiple system atrophy. March 1996 Movement Disorders: Olivopontocerebellar pathology in multiple system atrophy.
Association For Patient-Oriented Research Multiple System Atrophy and olivopontocerebellar atrophy mentioned. Evolution ofsporadic olivopontocerebellar atrophy into multiple system atrophy. http://www.mc.vanderbilt.edu/gcrc/aas/patient resources/SD-MSA news february 200
Extractions: 5. Curing Parkinson's Disease in Our Lifetime 1. Iron Metabolism and MSA Iron Problems May Lead to Parkinson's: Mouse study shows direct link January 30, 2001 article. Multiple System Atrophy and Olivopontocerebellar atrophy mentioned. Mouse With Iron Disorder Offers Clues To Parkinson's, Similar Diseases January 31, 2001 article. MSA and OPCA mentioned 2. Oxidative Stress and MSA Oxidative Damage Linked Directly to Neurodegeneration
Ol : On Medical Dictionary Online olivopontocerebellar atrophy, Inherited olivopontocerebellar atrophy, Nonfamilial Olivopontocerebellar Degeneration Olivopontocerebellar Degenerations http://www.online-medical-dictionary.org/ol.asp?q=~Ol
The Spinocerebeller Ataxias Spinocerebellar atrophy I; olivopontocerebellar atrophy I (OPCA 1); Spinocerebellar atrophy II; olivopontocerebellar atrophy I, Holguin type; OPCA 2; http://www.compgene.com/sca.htm
Extractions: The spinocerebellar ataxias are a group of autosomal dominantly inherited ataxias with heterogeneous presentation. Characteristic CAG repeat expansions in the coding sequences at several loci have been detected for certain of these disorders. Hence, a direct DNA test can provide an unequivocal diagnostic result for what are often complex clinical presentations. The loci reponsible for this group of disorders continues to grow and are the subject of research strategies evaluating trinucleotide (especially CAG trinucleotide) repeat expansions. A recent comprehensive clinical and molecular genetic reference is provided by Koshy and Zoghbi (1997), Brain Pathology 7:927-942. Although this is a recent review, it is out of date as the locus for SCA7 has been recently described (David et al. (1997) Nature Genetics 17:65-70; Koob et al. (1998) Nature Genetics 18:72-75.) The Table below provides a cross-reference of SCA genetic loci and a variety of alternative clinical names. In addition, by clicking on the highlighted OMIM reference number, you will be linked to the appropriate OMIM page. These pages provide current reviews of the genetics and clinical features of these disorders.
Search By Disease olivopontocerebellar atrophy III (OPCA3). 33, olivopontocerebellar atrophy,Holguin type. 34, olivopontocerebellar atrophy, neonatal (OPCA neonatal) http://www.eddnal.com/directory/disease.php?letter=O&page=3
Extractions: Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Request Permissions PubMed PubMed Citation Articles by Ozawa, T. Articles by Revesz, T. Received June 7, 2004
By A Everybody agrees that olivopontocerebellar atrophy is superinenarrable, as St.Augustine described the supremely indescribable. http://www.aepwall.com/OPCA page.htm
Extractions: see second article below, on this page To learn more about OPCA go to www.alyshia.com/opca/ On The Living Church cover, at right, the Rev. Canon Nelson Pinder speaks in favor of a new school tax in Orlando, Florida. Canon Pinder is a retired priest of the Episcopal Diocese of Central Florida who, despite retirement, is active in the Central Florida church and community and in the Episcopal Church at the national level. Photo by Frank Rivera of the Orlando Sentinel , which is one of the nation's better newspapers. (Full disclosure: I've written more than a hundred op-ed columns for the Orlando Sentinel and read it daily via the Internet.) To get to HOME PAGE click here Is this disease a woozydoozy, or what? By A. E. P. (Ed) Wall E verybody agrees that olivopontocerebellar atrophy is superinenarrable, as St. Augustine described the supremely indescribable. The relative handful of people who have the disease abbreviate it OPCA, but thatÂ’s not a lot of help. OPCA could (and does) also stand for Ohio Pest Control Assn. or Oregon Police Canine Assn., rather than a murderous ailment listed in the exclusive ranks of the National Organization for Rare Disorders.
Extractions: Smiley-Oyen, Ann L and Worringham, Charles J and Cross, Carol L (2003) Motor learning processes in a movement-scaling task in olivopontocerebellar atrophy and Parkinson's disease. Experimental Brain Research Full text available as: PDF - Requires Adobe Acrobat Reader or other PDF viewer. EPrint Type: Journal (Paginated) Status: Published Refereed: Yes Keywords: Motor learning; Parkinson's disease, OPCA, cerebellar disease; scaling; schema; skill; retention Subjects: .QUT Faculties and Divisions Faculty of Health ID Code: Deposited By: Worringham, Charles Deposited On: 09 March 2005 Alternative Locations: Additional Information: Subscribers can also access the publisher version of this paper via SpringerLink. Use the hypertext link above. QUT Division of Technolgy, Information and Learning Support Library ITS ... Office of Research Cricos No. 00213J Accessibility Privacy Last updated 28.10.03 QUT ePrints Administrator
