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► Olivopontocerebellar Atrophy A medical encycopedia article on the topic olivopontocerebellar atrophy. http://www.umm.edu/ency/article/000758.htm
Extractions: Causes, incidence, and risk factors: This condition can be inherited but it most commonly affects people without a known family history (sporadic form). Sporadic cases tend to affect people in their 50s while familial cases usually start earlier. The cause of sporadic olivopontocerebellar atrophy is not known, but the disease is progressive.
► Olivopontocerebellar Atrophy A medical encycopedia article on the topic olivopontocerebellar atrophy. http://www.umm.edu/ency/article/000758sym.htm
Extractions: Signs and tests: A thorough medical and neurological examination as well as a good history of symptoms and family history are necessary to make the diagnosis. There are no specific tests for this condition. An MRI of the brain may show a small cerebellum or brainstem, or atrophied olives. This is helpful in making the diagnosis but lack of these findings do not necessarily rule this condition out. Other tests may be done to rule out other diagnoses. Swallowing studies can be done to evaluate a patient's ability to swallow food and liquid safely.
Dr. Koop - Olivopontocerebellar Atrophy olivopontocerebellar atrophy is a neurodegenerative illness that causes certainbrain areas (which may include the olivary nucleus, the pons, http://www.drkoop.com/ency/93/000758.html
Extractions: Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Injury Disease Nutrition Poison ... Prevention Definition: Olivopontocerebellar atrophy is a neurodegenerative illness that causes certain brain areas (which may include the olivary nucleus, the pons, and the cerebellum) to shrink. Causes, incidence, and risk factors: The cause of sporadic olivopontocerebellar atrophy is not known, but the disease is progressive. This condition can be inherited or affect people without a known family history (sporadic form). Symptoms tend to start sooner in people with the familial form. This disease is slightly more common in men than in women. * All Health Centers * Acne Addictions AIDS/HIV Alcohol Abuse Allergies Alternative Medicine Alzheimer's Arthritis Asthma Attention Deficit Disorder (ADHD) Backache Bipolar Affective Disorder Birth Control Blood Blood Pressure Bone/Joint/Tendon Bowel Brain Breast cancer Cancer Cerebral Palsy Cholesterol Cramps Crohn's Disease Cysts Dental/Oral Depression Diabetes Diet, Fitness, Looks
Extractions: n. A progressive neurologic disease marked by loss of neurons in the cerebellar cortex, the pons, and the olivary nucleus. Wikipedia Olivopontocerebellar atrophy These are a group of diseases characterized by neuronal degeneration in the cerebellum , pontine nuclei, and inferior olive. They are also referred to as spinocerebellar atrophies or ataxias (SCA). Some also involve brain stem motor nuclei and/or cerebral cortex. All produce gait ataxia, and some also result in tremors, proprioceptive abnormalities, dysarthria , brain stem motor impairment, or dementia. Most are autosomal dominant in inderitance pattern. The primary cause of these hereditary ataxias also appears to be an unstable expansion of the repeat trinucleotide CAG, similar to Huntington's disease This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see Mentioned In Olivopontocerebellar atrophy is mentioned in the following topics: Multiple system atrophy List of diseases starting with O List of neurological disorders List of biomedical topics, O
List Of Diseases Starting With O: Information From Answers.com olivopontocerebellar atrophy deafness; olivopontocerebellar atrophy type 1 olivopontocerebellar atrophy type 3; olivopontocerebellar atrophy http://www.answers.com/topic/list-of-diseases-starting-with-o
Extractions: showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Wikipedia Or search: - The Web - Images - News - Blogs - Shopping List of diseases starting with O Wikipedia List of diseases starting with O A list of diseases in the English wikipedia. A B C D ... N O P Q R S ... Z Ocula Oculo Oculoa-Oculog Oculoauriculofrontonasal syndrome Oculoauriculovertebral dysplasia Oculocerebral hypopigmentation syndrome Cross type Oculocerebral hypopigmentation syndrome type Preus Oculocerebral syndrome with hypopigmentation Oculocerebrocutaneous syndrome Oculocerebrorenal syndrome Oculocutaneous albinism immunodeficiency Oculocutaneous albinism type 1 Oculocutaneous albinism type 2 Oculocutaneous albinism type 3
Olivopontocerebellar Atrophy, Hereditary Hereditary olivopontocerebellar atrophy (OPCA) is a rare group of disorderscharacterized by progressive http://webcenter.health.webmd.netscape.com/hw/brain_nervous_system/nord495.asp
Extractions: Hereditary olivopontocerebellar atrophy (OPCA) is a rare group of disorders characterized by progressive balance problems (disequilibrium), progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia), and difficulty speaking or slurred speech (dysarthria). There are at least five distinct forms of hereditary OPCA. All forms of hereditary OPCA, except one, are inherited as autosomal dominant traits.
Extractions: Advanced Search Or click the first letter of a drug name: A B C D ... Z Injury Disease Nutrition Poison ... Central nervous system Olivopontocerebellar atrophy is a neurodegenerative illness that causes certain brain areas (which may include the olivary nucleus, the pons, and the cerebellum) to shrink. OPCA; Olivopontocerebellar degeneration The cause of sporadic olivopontocerebellar atrophy is not known, but the disease is progressive. This condition can be inherited or affect people without a known family history (sporadic form). Symptoms tend to start sooner in people with the familial form. This disease is slightly more common in men than in women. Many symptoms are associated with olivopontocerebellar atrophy but the predominant feature is progressive ataxia (clumsiness) and difficulties with balance. There may be slurring of speech and difficulty walking. Other symptoms may include:
Olivopontocerebellar Atrophy Multiple system atrophy is a degenerative disorder characterized by progressivedamage to the autonomic nervous system. http://neurology.health-cares.net/olivopontocerebellar-atrophy.php
Multiple System Atrophy olivopontocerebellar atrophy (OPCA) when cerebellar signs predominate, andShyDrager syndrome when autonomic failure is dominant. http://neurology.health-cares.net/multiple-system-atrophy.php
Olivopontocerebellar Atrophy (OPCA) olivopontocerebellar atrophy. What is olivopontocerebellar atrophy? Olivopontocerebellaratrophy (OPCA) refers to a group of ataxias characterized by http://www.clevelandclinic.org/health/health-info/docs/0300/0326.asp?index=6072
Show-documents.asp olivopontocerebellar atrophy Written Information. Care Treatment. olivopontocerebellar atrophy New Search Contact Us Disclaimer Send This Link http://www.clevelandclinic.org/health/search/do-query.asp?TopicId=991
Olivopontocerebellar Atrophy, Hereditary Hereditary olivopontocerebellar atrophy (OPCA) is a rare group of disorderscharacterized by progressive balance problems (disequilibrium), http://www.bchealthguide.org/kbase/nord/nord495.htm
Extractions: It is possible that the main title of the report Olivopontocerebellar Atrophy, Hereditary is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Hereditary olivopontocerebellar atrophy (OPCA) is a rare group of disorders characterized by progressive balance problems (disequilibrium), progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia), and difficulty speaking or slurred speech (dysarthria). There are at least five distinct forms of hereditary OPCA. All forms of hereditary OPCA, except one, are inherited as autosomal dominant traits. WE MOVE (Worldwide Education and Awareness for Movement Disorders)
Lamb olivopontocerebellar atrophy (OPCA) is a disease characterized primarily by Campbell, T. Dysphagia in familial olivopontocerebellar atrophy Effects of http://web.indstate.edu/thcme/anderson/ML.html
Extractions: Olivopontocerebellar Atrophy Mark Lamb Abstract Olivopontocerebellar Atrophy(OPCA), is characterized by neuronal degeneration of the cerebellar cortex, the inferior olive, and the pons. The symptoms associated with it are primarily cerebellar ataxia with disturbances in equilibrium and gait. However, broader symptomology is usually seen with OPCA. Current research is focusing on three primary systems thought to be responsible for the etiology of OPCA. They are excitatory amino acid disturbances, oligodendroglial microtubular tangles, and phospholipid metabolism disorders. The only treatment for OPCA is therapy focusing on improving the dysphagia associated with the disorder. Olivopontocerebellar Atrophy Olivopontocerebellar Atrophy (OPCA) is a disease characterized primarily by the degeneration of neurons in the cerebellar cortex, pons, and inferior olive. It is a genetic disease, being either autosomal dominant or autosomal recessive in nature. This disorder, which usually occurs in the middle years of life, presents symptoms of cerebellar ataxia, equilibrium disturbance, nystagmus, dysphasia, dysarthria, and possibly intellectual deficits. According to Merritt, the pathology of OPCA includes loss of Purkinje cells, reduction of the number of neurons in the molecular and granular layers of the cerebellum, degeneration of the folia and white matter of the cerebellum, atrophy of the inferior olives and of the olivo-cerebellar connections, and atrophy of the pontine nuclei, arcuate nuclei, and brachium pontis (15). In addition to this, degeneration of the spinocerebellar tracts, corticospinal tracts, and frontal and temporal lobes has been reported (15).
Opca/ds olivopontocerebellar atrophy (OPCA) was first described in 1900 by Dejerine and Cognitive Deficits in olivopontocerebellar atrophy Implications for the http://web.indstate.edu/thcme/anderson/DS.html
Extractions: OLIVOPONTOCEREBELLAR ATROPHY Debra Stenacker Olivopontocerebellar atrophy (OPCA) was first described in 1900 by Dejerine and Thomas. OPCA is a group of dominant inheritance and sporadic neurological disorders characterized by a chronic, progressive, cerebellar ataxia that begins in middle age. The cerebellum and its connections are the primary sites of the disease in chronic progressive disorders that often occur in familial or hereditary patterns. Postmortem studies indicate an atrophy of the cerebellum, pons, and inferior olives. This neuropathological neuronal cell loss permits classification of OPCA as a non-Alzheimers neurodegenerative illness. Gross postmortem inspection of the brains of patients with OPCA shows marked shrinkage of the ventral half of the pons, and disappearance of the olivary eminence on the ventral surface of the medulla. These brains also exhibit an atrophy of the cerebellum with degeneration of the middle cerebellar peduncles, and to a lesser extent, of the inferior peduncles. Thus, the cerebellum suffers mainly through atrophy of its afferent fibers. The neocerebellum and the olive undergo the primary degeneration. The purkinje cells of the cerebellar cortex are affected secondarily. Histological examination shows severe degeneration of Purkinje cells, reduction in the number of cells in the molecular and granular layers of the cerebellar cortex, severe loss of the number of cells in the pontine nuclei and olives, and demyelination of the middle cerebellar peduncle. The cerebellar nuclei are well preserved. The tegmentum of the pons, the corticospinal tracts, and the restiform body are also usually unaffected. In clinical cases involving extrapyramidal symptoms, degenerative changes in the striatum, especially the putamen, and a loss of pigmented cells in the substantia nigra may be seen. Tubular structures and crystalline inclusions may be found with the electron microscopy. More wide spread degeneration of the central nervous system has been reported in dominant autosomal cases, and may involve the spinocerebellar fibers and the posterior columns.
Re: Olivopontocerebellar Atrophy The Neurology and Neurosurgery Forum ask the doctor medical forum for patientshosted by Med Help Intl. http://www.medhelp.org/forums/neuro/archive/15044.html
Extractions: : Hello: : Can you tell me what diagnostic test currently are used to diagnose and confirm OPCA? : Thank you very much!! Dear Dave: Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. Heredofamilial cerebellar degenerations can be either autosomal dominant (various types termed spinocerebellar ataxia = SCA 1 - 7, DRPLA, Machado-Joseph disease, etc) or autosomal recessive (Friedreich's ataxia, and some other rare types). The syndrome of progressive ataxia (imbalance of gait, incoordination of hands, slurred speech), in association with some other characteristic abnormalities (peripheral neuropathy, optic atrophy, retinitis pigmentosa, dementia, corticospinal dysfunction, oculomotor dysfunction, etc) is seen with heredofamilial forms. Ataxia is associated with autonomic dysfunction and/or parkinsonian features in sporadic cases. Either sporadic or autosomal dominant forms of cerebellar degeneration can be associated with atrophy of the cerebellum, pons and inferior olives, either on MRI, or at autopsy. Hence, OPCA (olivopontocerebellar atrophy) is used as a descriptive term for these disorders.
Olivopontocerebellar Atrophy Patient medical question and doctor answer from The Neurology and NeurosurgeryForum. Health topic area and articles about neurology general Topics http://www.medhelp.org/forums/neuro/archive/15346.html
Extractions: : : Hello: : : Can you tell me what diagnostic test currently are used to diagnose and confirm OPCA? : : Thank you very much!! : Dear Dave: : Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. Heredofamilial cerebellar degenerations can be either autosomal dominant (various types termed spinocerebellar ataxia = SCA 1 - 7, DRPLA, Machado-Joseph disease, etc) or autosomal recessive (Friedreich's ataxia, and some other rare types). : The syndrome of progressive ataxia (imbalance of gait, incoordination of hands, slurred speech), in association with some other characteristic abnormalities (peripheral neuropathy, optic atrophy, retinitis pigmentosa, dementia, corticospinal dysfunction, oculomotor dysfunction, etc) is seen with heredofamilial forms. Ataxia is associated with autonomic dysfunction and/or parkinsonian features in sporadic cases. Either sporadic or autosomal dominant forms of cerebellar degeneration can be associated with atrophy of the cerebellum, pons and inferior olives, either on MRI, or at autopsy. Hence, OPCA (olivopontocerebellar atrophy) is used as a descriptive term for these disorders. : The diagnosis of sporadic cerebellar degeneration or OPCA remains clinical. Isolated cases of heredofamilial cerebellar degeneration, and some specific secondary causes of cerebellar degeneration (such as with malignancies or toxins) need to be excluded.
Olivopontocerebellar Atrophy The Essentials on olivopontocerebellar atrophy Guidelines. Overview. What Isolivopontocerebellar atrophy? Is There Any Treatment? What Is the Prognosis? http://www.icongrouponline.com/health/Olivopontocerebellar_Atrophy.html
Extractions: (Atrophy Olivopontocerebellar; Multiple systems atrophy; Olivopontocerebellar degeneration; Spinocerebellar Ataxia Type IV; Spinocerebellar Ataxia Type V; Spinocerebellar Ataxia Type VI; Spinocerebellar Ataxia Type VII; Spinocerebellar Atrophy Type I) Revised and Updated for the Internet Age P A P E R B A C K Paperback Book Paperback Book Order by phone: 800-843-2665 (within USA) 1-201-272-3651 (from outside USA) Paperback Book Shipped in 3 to 5 business days E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Pages Price $28.95(USD) ISBN Published Synopsis A comprehensive manual for anyone interested in self-directed research on Olivopontocerebellar Atrophy. Fully referenced with ample Internet listings and glossary. Related Conditions/Synonyms Atrophy Olivopontocerebellar; Multiple systems atrophy; Olivopontocerebellar degeneration; Spinocerebellar Ataxia Type IV; Spinocerebellar Ataxia Type V; Spinocerebellar Ataxia Type VI; Spinocerebellar Ataxia Type VII; Spinocerebellar Atrophy Type I Description Table of Contents Introduction Overview Organization Scope Moving Forward PART I: THE ESSENTIALS Chapter 1. The Essentials on Olivopontocerebellar Atrophy: Guidelines
