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Neuroleptic Malignant Syndrome:     more detail

Neuroleptic Malignant Syndrome and Related Conditions by Stephan C. Mann, Stanley N. Caroff, et all 2003-04 Neuroleptic Malignant Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications, 2004-12-06 Neuroleptic Malignant Syndrome: A Clinical Approach by Gerard Addonizio, Virginia L. Susman, 1991-02 Treatment of Schizophrenia: Schizophrenia, Recovery Model, Chlorpromazine, Neuroleptic Malignant Syndrome, Tardive Dyskinesia, World Health Organization Extrapyramidal and Movement Disorders: Neuroleptic Malignant Syndrome, Essential Tremor, Restless Legs Syndrome, Dystonia Neuroleptic malignant syndrome in a patient with Parkinson's disease: a case study.: An article from: Journal of Neuroscience Nursing by Constance Ward, 2005-06-01 Neuroleptic malignant syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Rosalyn, MD Carson-DeWitt, 2005 Atypical neuroleptic malignant syndrome presenting as fever of unknown origin in the elderly.(Case Report): An article from: Southern Medical Journal by Ryan C.W. Hall, Brian Appleby, et all 2005-01-01 Hyperthermic and Hypermetabolic Disorders: Exertional Heat-Stroke, Malignant Hyperthermia and Related Syndromes Drug Induced Movement Disorders Medication-induced movement disorders: An entry from Thomson Gale's <i>Gale Encyclopedia of Mental Disorders</i> by Ajna, Pharm.D. Hamidovic, 2003

lists with details

81. Neuroleptic Malignant Syndrome And Mivacurium: A Safe Alternative To Succinylcho
    neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) may have acommon pathogenic mechanism; therefore, it has been suggested that known  
    http://www.cja-jca.org/cgi/content/abstract/41/9/845
    
    Extractions: HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by Kelly, D. Articles by Brull, S. J. D Kelly and SJ Brull Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510. Neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) may have a common pathogenic mechanism; therefore, it has been suggested that known triggering agents for MH (such as succinylcholine) should be avoided in patients with NMS. Electroconvulsive therapy (ECT) continues to play a major therapeutic role in contemporary psychiatry, and succinylcholine has been the muscle relaxant of choice in attenuating violent muscle contractions induced by ECT. Mivacurium is a non-depolarizing muscle

82. Item Detail - Article: Treatment Of Neuroleptic Malignant Syndrome - Malignant H
    MHAUS is the only association in the United States dedicated to the control ofmalignant hyperthermia (MH), a lifethreatening genetic disorder.  
    http://www.mhaus.org/index.cfm/fuseaction/eShop.ItemGroupDetail/ItemGroupPK/F01E

83. Item Detail - Brochure: Neuroleptic Malignant Syndrome Information Service - Mal
    MHAUS is the only association in the United States dedicated to the control ofmalignant hyperthermia (MH), a lifethreatening genetic disorder.  
    http://www.mhaus.org/index.cfm/fuseaction/eShop.ItemGroupDetail/ItemGroupPK/EFD0

84. U.S. Pharmacist
    AGE/INCIDENCE ASSOCIATION NOT FOUND IN neuroleptic malignant syndrome As diagnostic criteria for neuroleptic malignant syndrome typically encompass a  
    http://www.uspharmacist.com/index.asp?show=article&page=8_1405.htm

85. Obstetrics & Gynecology -- Sign In Page
    BACKGROUND neuroleptic malignant syndrome can be a serious neurologic neuroleptic malignant syndrome is a potentially lethal complication of treatment  
    http://www.greenjournal.org/cgi/content/full/98/5/906
    
    Extractions: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Russell, C. S. Articles by Calhoun, B. To view this item, select one of the options below: Sign In User Name Sign in without cookies.

86. Neuroleptic Malignant Syndrome Articles, Support Groups, And Resources
    neuroleptic malignant syndrome articles, support groups, and resources for patientsfrom Med Help International (www.medhelp.org)  
    http://www.medhelp.org/HealthTopics/Neuroleptic_Malignant_Syndrome.html

87. NEUROLEPTIC MALIGNANT SYNDROME
    neuroleptic malignant syndrome This describes the combination of catatonicrigidity, stupor, unstable blood pressure, fever, profuse sweating, sweating,  
    http://www.medhelp.org/glossary2/new/GLS_3312.HTM

88. Early Recognition Of Neuroleptic Malignant Syndrome During Traumatic Bain Injury
    Kadyan, V., Colachis, S., DePalma, L., Samderson, J., Mysiw, W. Early recognitionof neuroleptic malignant syndrome during traumatic bain injury  
    http://www.tbindc.org/registry/searchresults.php?searchparam=publication/id/635

89. Neuroleptic Malignant Syndrome Induced By Haloperidol Following Traumatic Brain
    Wilkinson, W., Meythaler, J., GuinRenfroe, S. neuroleptic malignant syndromeinduced by haloperidol following traumatic brain injury.  
    http://www.tbindc.org/registry/searchresults.php?searchparam=publication/id/922

90. Neuroleptic-induced Extrapyramidal Symptoms With Fever: Heterogeneity Of The 'ne
    Neurolepticinduced extrapyramidal symptoms with fever heterogeneity ofthe neuroleptic malignant syndrome . Levinson DF, Simpson GM  
    http://www.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/86322351

91. Facilitating Prompt Diagnosis And Treatment Of The Neuroleptic Malignant Syndrom
    Facilitating prompt diagnosis and treatment of the neuroleptic malignant syndrome.Nierenberg D, Disch M, Manheimer E, et al.  
    http://www.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/92036048

92. Directory Of Open Access Journals
    Title, Olanzapineassociated neuroleptic malignant syndrome Is there an Key words, neuroleptic malignant syndrome; serotonin syndrome; olanzapine  
    http://www.doaj.org/abstract?id=82890&toc=y

93. Arquivos De Neuro-Psiquiatria -
    Translate this page neuroleptic malignant syndrome case report of a recurrence related to olanzapine.ABSTRACT - The neuroleptic malignant syndrome (NMS) consists in an  
    http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1998000500022

94. Sao Paulo Medical Journal -
    CONTEXT A case of neuroleptic malignant syndrome and acute respiratory neuroleptic malignant syndrome is a disease that is difficult to diagnose.  
    http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802003000300007

95. Antidepressants Facts: Serotonin Syndrome SSRI's, SSNRI's
    from the neuroleptic malignant syndrome because the symptoms are so similar.The neuroleptic malignant syndrome is a serious condition brought on by the  
    http://www.antidepressantsfacts.com/serotonin-syndrome-ADF.htm
    
    Extractions: T he Serotonin Syndrome is a hyperserotonergic state which is a very dangerous and a potentially fatal side effect of serotonergic enhancing drugs which can have multiple psychiatric and non-psychiatric symptoms. This is a toxic condition which requires heightened clinical awareness in order to prevent, recognize, and treat the condition promptly. Promptness is vital because, as we just mentioned, the serotonin syndrome can be fatal and death from this side effect can come very rapidly. This syndrome is a toxic hyperserotonergic state whose rate of incidence is unknown, but is on the rise. This disorder, brought on by excessive levels of serotonin, is difficult to distinguish from the neuroleptic malignant syndrome because the symptoms are so similar. The neuroleptic malignant syndrome is a serious condition brought on by the use of the neuroleptic drugs.

96. Neuroleptic Malignant Syndrome (Treatment Guide)
    neuroleptic malignant syndrome DEFINITION A lifethreatening idiosyncratic reactioncharacterized by muscle rigidity and hyperthermia, related to acute  
    http://www.intox.org/databank/documents/treat/treate/trt37_e.htm
    
    Extractions: NEUROLEPTIC MALIGNANT SYNDROME DEFINITION A life-threatening idiosyncratic reaction characterized by muscle rigidity and hyperthermia, related to acute dopamine depletion, either from the use of neuroleptic drugs or of dopamine antagonists, or the withdrawal of dopamine agonists. TOXIC CAUSES Exposure to therapeutic doses of potent neuroleptic drugs (eg, haloperidol, fluphenazine) or the sudden cessation of dopamine agonists such as amantidine. Reported risk factors include dehydration and the concurrent use of lithium and tricyclic antidepressants. CLINICAL FEATURES Extreme hyperpyrexia, lead-pipe muscular rigidity, autonomic dysfunction (tachycardia, elevated or fluctuating blood pressure), sweating, tachypnoea, respiratory failure, altered mental status (confusion, delirium, stupor and coma), extrapyramidal signs (e.g. cogwheel hypertonia). Acute myoglobinuric renal failure may occur. The condition is fatal in up to 12 % of cases DIFFERENTIAL DIAGNOSIS Anticholinergic poisoning Catatonia CNS infections CNS mass lesions Ethanol or sedative-hypnotic drug withdrawal Extrapyramidal symptoms with fever Heat-stroke (environmental or exertional) Malignant hyperthermia Metal fume fever Psychiatric disorders Septicaemia Strychnine poisoning Thyroid storm Tetanus Tetany RELEVANT INVESTIGATIONS Laboratory tests are generally non-specific, but may be used to exclude alternative diagnoses. Arterial blood gases - metabolic acidosis is usually present. Creatinine phosphokinase activity - commonly elevated; marked elevations may indicate a serious risk of acute renal failure. CT scan of the head may be obtained to rule out CNS lesions. Electrolytes - hyperkalaemia, hyper- or hyponatraemia, hypocalcaemia. Liver function tests are not characteristic, but may be elevated. Lumbar puncture to rule out CNS infection. Renal function - urea, creatinine. Standard fever work-up to rule out infections. Urinalysis - urinary myoglobin or myoglobin casts may be present White blood cell count - leukocytosis may be present, (between 12,000 and 30,000 /mm

97. Indian Journal Of Psychiatry
    neuroleptic malignant syndrome (NMS) is an uncommon but potentially serious neuroleptic malignant syndrome (NMS) (Delay Deniker, 1968) is a rare,  
    http://www.ijponline.org/JanMar2003/article7.html
    
    Extractions: Risk Factors in Neuroleptic Malignant Syndrome VINAY GUPTA, RAKESH MAGON, B.P. MISHRA, G.B.S. SIDHU, RANJIV MAHAJAN ABSTRACT Neuroleptic malignant syndrome (NMS) is an uncommon but potentially serious idiosyncratic response to neuroleptic antipsychotics. It usually affects young males, but the risk has been seen to increase with certain factors including the administration practices of antipsychotic neuroleptics in these individuals. Even though no predictors for NMS are yet known, this article highlights the findings on certain risk factors as seen from a series of fifteen patients who developed NMS. Cautious use of neuroleptics in those at risk, early recognition and institution of immediate management is important. Top

98. CUADERNOS DE NEUROLOGIA
    Translate this page Caroff S, Mann S, Campbell E. neuroleptic malignant syndrome. Adverse Drug ReactBull. Buckley PF, Hutchinson M. neuroleptic malignant syndrome.  
    http://escuela.med.puc.cl/publ/Cuadernos/2003/Neuroleptico.html
    
    Extractions: Factores de riesgo Tratamiento El paciente debe ingresar a una unidad de cuidados intensivos y se debe suspender inmediatamente los NL. De ser necesario reiniciar los NL, se deben esperar al menos dos semanas de resuelto el SNM, para intentar evitar una recurrencia del cuadro. Idealmente se debe utilizar un NL de menor potencia, de todas formas el riesgo de recurrencia es de un 15%. Referencias: Delay J, Deniker P. Sur quelque erreurs de prescription des medicament psychiatrique. Bull Mem Soc Med Hop Paris. 1965; 116: 487. Caroff S, Mann S, Campbell E. Neuroleptic malignant syndrome. Adverse Drug React Bull. 2001; 209: 799-802. Caroff S, Rosenberg H, Mann S, Campbell E, Sullivan K. Neuroleptic malignant syndrome in the perioperative setting. Am J Anesthesiol. 2001; 28: 387-93. Rodintzky R. Drug-induced disorders in children. Sem in Pediatr Neurol. 2003; 10: 80-7 Carbone J. The neuroleptic malignant syndrome and serotonin syndrome. Emerg Med Clin North Am. 2000; 18: 317-25. Henderson V, Wooten C. Neuroleptic malignant syndrome: A pathogenetic role for dopamine receptor blockade? Neurology. 1981; 31: 132-7.

99. Current Psychiatry Online
    Probable or definite neuroleptic malignant syndrome cases associated with Source neuroleptic malignant syndrome Information Service hotline  
    http://www.currentpsychiatry.com/article_pages.asp?AID=704&UID=187

100. The American Journal Of The Medical Sciences - UserLogin
     Acute Hypernatremia and neuroleptic malignant syndrome in Parkinson Disease neuroleptic malignant syndrome is a clinical syndrome characterized by fever  
     http://www.amjmedsci.com/pt/re/ajms/fulltext.00000441-199907000-00011.htm

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