Institute For Vaccine Safety - IOM Thimerosal-Containing Vaccines between neurodevelopmental disorders and thimerosalcontaining vaccines. The committee recommends further analysis of neurodevelopmental disorders in http://www.vaccinesafety.edu/IOM-thimerosal-10-01-01.htm
Extractions: Institute of Medicine report on thimerosal-containing vaccines and neurodevelopmental disorders This information is adapted from the Institute of Medicine (IOM) Report on Thimerosal-Containing Vaccines and Neurodevelopmental Disorders. On October 1, 2001, the Institute of Medicine's Immunization Safety Review Committee released its report examining whether or not the use of vaccines containing the preservative thimerosal can cause neurodevelopmental disorders, specifically autism, attention deficit/hyperactivity disorder (ADHD), and speech or language delay. The Committee concluded, "The hyphothesis that thimerosal exposure through the recommended childhood immunization schedule has caused neurodevelopmental disorders is not supported by clinical or experimental evidence." However, the Committee also acknowledged that the epidemiological evidence was inadequate to either accept or reject a causal relationship.
Extractions: Neurodevelopmental disorders encompass a diverse group of individuals with a variety of specific disorders such as attention deficit disorders (ADHD), developmental language disorders (DLD), learning disabilities (LD), epilepsy, pervasive developmental disorders/autistic spectrum disorders (PDD/ASD), Tourette syndrome, and other less specific conditions such as mental retardation, cerebral palsy, and behavioral problems. The prevalence of some of these disorders is presented below: Disorder Prevalence Attention Deficit Disorder 3-5% of school age children Developmental Language Disorders 3-5% of school age children Learning Disabilities 5% of school age children Epilepsy 1% of individuals Pervasive Developmental Disorders 0.1% of individuals Tourette Syndrome 0.5 per 1000 individuals
Special Web Supplement -- Brain Disease: Neurodevelopmental Disorders Brain Disease neurodevelopmental disorders we offer links to resources on two devastating postnatal neurodevelopmental disorders reviewed by Zoghbi in http://www.sciencemag.org/sciext/braindisease/neurodevelopmental.shtml
Science -- Sign In We often think of neurodevelopmental disorders as beginning before birth, Epigenetic overlap in autismspectrum neurodevelopmental disorders MECP2 http://www.sciencemag.org/cgi/content/full/302/5646/826
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Extractions: Text Size A A A Front Page ... Disorders : Neurodevelopmental One Hit Of Crystal Meth Causes Birth Defects, Affects Fetuses At All Stages Of Development (July 27, 2005) full story 'Brown Fat' Cells Hold Clues For Possible Obesity Treatments (June 8, 2005) full story Infants With Rare Genetic Disease Saved By Cord Blood Stem Cells (May 27, 2005) full story New Theory Explains Schizophrenia As Abnormal Courtship; Disorder Survives As Marker For Bad Genes (March 25, 2005) full story Could Schizophrenia Arise From A Single Defect? (March 2, 2005) full story Alcohol's Damaging Effects On Adolescent Brain Function (February 22, 2005) full story Abnormal Brain Activity During The Observation Of Others' Actions (February 18, 2005) full story Columbia Researcher Identifies Cellular Defect That May Contribute To Autism (January 31, 2005) full story [ More news about Neurodevelopmental
CEHN: Index Of Children's Environmental Health Resources on the Network s web site that provide information on neurodevelopmental disorders? Click on the following links to neurodevelopmental disorders on the http://www.cehn.org/cehn/resourceguide/neurodeveldisorders.html
Extractions: NEURODEVELOPMENTAL DISORDERS The term neurodevelopmental disorder is fairly new in developmental medicine and related fields. It refers to a group of difficulties wherein there are gaps, delays or variations in the way a childs brain develops. It can be caused by genetic, environmental, or unspecified reasons, many of which are not yet known. We do know however that these dysfunctions often interfere with learning, behavior and adaptability across environments. Neurodevelopmental problems affect one out of every 20 children. Because of the brain disruption which is at the root of all neurodevelopmental disorder s , there are several common features across the variety of disorders in this group. Some of these include difficulties with motor development, sensory integration difficulties, speech and language delays and a range of cognitive difficulties including learning disabilities, poor organizational skills, poor self regulation and behavioral difficulties.
Neurodevelopmental Disorders neurodevelopmental disorders. The developing nervous system is particularly vulnerable very early in life to damaging effects of exposure to specific http://www.euro.who.int/childhealthenv/Risks/NeuroTop
Extractions: Programmes and projects Children's health and environment Home Children's health and environment Home News and events Case studies Children's Environment and Health Action Plan for Europe (CEHAPE) ... Contacts Neurodevelopmental disorders The developing nervous system is particularly vulnerable very early in life to damaging effects of exposure to specific contaminants such as lead, methylmercury and polychlorinated biphenyls (PCBs). A child can absorb as much as 50% of the lead present in food, while an adult takes up only 10% (United States Environmental Protection Agency (US EPA) estimates in 1986). Exposure to such substances has been associated with developmental disabilities in the form of physical, cognitive, sensory and speech impairments, including in particular learning disabilities and intellectual retardation. Prevalence rates are up to about 10% in certain populations. When incurred early in life such developmental effects are likely to be permanent. Children's intellectual potential at risk. European Ministers finalize the Budapest Conference agenda Press release and fact sheet 25.3.2004 Lead continues to affect children's brains in parts of Europe, putting their development at risk. New research being carried out by WHO and the University of Udine (Italy) focuses on the burden of disease in children caused by chemicals and other environmental factors, such as indoor and outdoor air pollution, water and injuries. Early findings are released on the occasion of the final negotiations with countries prior to the Budapest Conference
Douglas Hospital Research Centre Schizophrenia and neurodevelopmental disorders Research Theme. Overview Principal Researchers Some Research Highlights Awards Distinctions http://www.douglasrecherche.qc.ca/researchPrograms/themes/schizophrenia/index.as
Douglas Hospital Research Centre Schizophrenia and neurodevelopmental disorders Research Theme Award from the National Alliance for Research in Schizophrenia and Affective Disorders, http://www.douglasrecherche.qc.ca/researchPrograms/themes/schizophrenia/awards.a
Extractions: saveBookmark("", "", ""); Home Other Subjects Psychology Study Guides Abnormal ... Schizophrenia : Potential Causes of the Neurodevelopmental Disorders Apparent in Schizophrenia - Navigate Here - Introduction and Summary Terms Socio-cultural Causes of Schizophrenia Psychological Causes of Schizophrenia Biological Causes of Schizophrenia Treatment for Schizophrenia Potential Causes of the Neurodevelopmental Disorders Apparent in Schizophrenia Study Questions Potential Causes of the Neurodevelopmental Disorders Apparent in Schizophrenia Several observations have suggested that neurodevelopmental problems associated with schizophrenia represent antecedents rather than consequences of the disorder. The concept of an unknown brain legion is a hypothetical construct that has been supported by evidence such as the latitude effect, which indicates that individuals who live at higher latitudes show an increased risk for developing more malignant forms of schizophrenia . The prenatal environment and gestation period may also play an important role. The seasonality effect describes findings that births occurring in late winter or early spring are associated with a higher risk for developing schizophrenia, especially when temperatures were very low the previous fall. Both the latitude effect and the seasonality effect, however, may point to the mother having contacted some viral infection, or developed some autoimmune response. Support for this theory can also be drawn from the evidence that the influenza epidemic of 1957 was associated with an increased rate of schizophrenia. Also, in times of severe food shortage, such as during the
Extractions: demonstrate a connection between mercury exposure via infant vaccinations and the dramatic increase in autism and other neurodevelopmental disorders in the United States. It is clear that the results of the present study, mandate that additional research should be undertaken, no only for autism, but other childhood neurodevelopmental disorders, by evaluating childhood mercury-associated exposures, especially from thimerosal-containing childhood vaccines."
Neurodevelopmental Disorders Cognitive-behavioural Phenotypes In recent years our approach to neurodevelopmental disorders has undergone neurodevelopmental disorders from a cognitive neurosciences perspective http://www.child-neuro.org.uk/content/publish/article_386.shtml
Neurodevelopmental Effects Thimerosal containing vaccines and neurodevelopmental disorders. Stratton K, Gable A, McCormick MC, eds. Washington DC National Academy Press, 2001. http://www.altcorp.com/DentalInformation/neurodevelopment.htm
Extractions: http://www.hc-sc.gc.ca/pphb-dgspsp/publicat/ccdr-rmtc/02vol28/dr2809ea.html Background . However, there are limited data examining the effects of low-dose, intermittent mercury exposure, for example, when infants are immunized with thimerosal-containing vaccines. Currently, the only thimerosal-containing vaccine in routine use in the infant immunization schedules of some Canadian jurisdictions is hepatitis B vaccine. In a statement released in December 1999 , Canadas National Advisory Committee on Immunization recommended no change to existing infant immunization programs for three reasons: absence of exposure (in eight provinces), or very low cumulative exposure of Canadian infants to vaccine-derived thimerosal (in two provinces and both territories where thimerosal-containing hepatitis B vaccine was, at that time, used in
Extractions: The usefulness of Essential Fatty Acids and micronutrient supplementation in neurodevelopmental Disorders. Jacques Duff. MAPS; MAAAPB; AMACNEM; MASNR Presented at the Australian Society for Neuronal Regulation Seminar, Sydney 2001. Of all the fatty acids found in foods, Omega 6, Linoleic acid (LA) and Omega 3, Alpha Linolenic Acid (ALA) cannot be manufactured by the body. These are called Essential Fatty Acids (EFA) since they must be present in the diet. The liver converts ALA into the long chain Omega 3 fatty acid, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA). Omega 6 essential fatty acids undergo a similar conversion. The balance of these two EFAs in our diet and cells is essential for the maintenance of optimum cell wall (membrane) structures. These long chain EFAs are necessary for laying out optimum myelin sheath on brain neurons, and they play a major role in cell membranes of the brain and the retina, as well as lowering blood plasma triglycerides and cholesterol levels. They also play an essential role in all cells, as they are an integral part of their protective membrane . Consequently deficits in these essential nutrients can lead to cellular malnutrition and "leaky" cell membranes that may allow antigens into the cell body.