Malaria Prophylaxis-Review Any fever up to 1218months after leaving a malaria area should arouse suspicion The WHO no longer recommends this combination for malaria prophylaxis. http://www.priory.com/malaria.htm
Extractions: The development of resistance to familiar anti-malarials has created confusion both for Doctors and travellers as to what is the best and most effective anti-malarial to take and which areas of the World require special precautions. Further difficulties are created by the serious side-effects encountered on using the newer drugs. This review will endeavour to elucidate current areas of resistance and recommendations for prophylaxis and treatment. Great stress is given to the warning that no prophylaxis is foolproof and failures arise most commonly from not taking the drugs as prescribed. In particular they must be started 1 week before departure and continued for 4-6 weeks after leaving the malaria area. Any fever up to 12-18months after leaving a malaria area should arouse suspicion of malaria and be investigated accordingly. Appropriate advice must be sought prior to departure from a reputable travel advice centre. Antimalarial drugs
Roll Back Malaria Department Global Partnership hosted by the World Health Organization enabling countries to take effective, sustainable action against malaria, focusing on prompt access to effective treatment, prevention and control of malaria during pregnancy, promotion of insecticidetreated mosquito nets as a means of prevention, and anti-malaria strategies for emergency and epidemic situations. http://mosquito.who.int/
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Plasmodium (malaria) malaria has been recognized as an important parasitic disease of humans for centuries, Four species of Plasmodium infect humans and cause malaria. http://www.biosci.ohio-state.edu/~parasite/plasmodium.html
Extractions: (malaria) Malaria has been recognized as an important parasitic disease of humans for centuries, having been described by the early Egyptians in the third millennium B.C. Despite the introduction of control programs in many parts of the world over the past few decades, the impact of malaria on human populations continues to increase. Recent estimates suggest (1) that 1.5 billion persons live in areas of the world where malaria is an endemic disease, (2) that the number of infected humans exceeds 500,000,000, and (3) that 1-2 million persons die each year. Four species of Plasmodium infect humans and cause malaria. All species are vector borne diseases, being spread by anopheline mosquitoes , and the disease is distributed throughout much of the world ( view distribution ). In the human host the parasite is found primarily inside of the red blood cells (RBC). The parasite reproduces asexually inside of the RBC, and following this the RBC breaks open releasing many new parasites (merozoites). These parasites then infect more RBC's, and this ultimately leads to the destruction of massive numbers of RBC's. The characteristic "chill and fever" (paroxysm) associated with malaria occurs when the parasites are released from the RBC's, and since the release of parasites is periodic, the paroxysms are periodic. For examples, the paroxysms associated with a tertian malaria (e.g., Plasmodium vivax ) occur about ever 48 hours, and those associated with a quarten malaria (e.g.
Extractions: Assessments of the potential impact of global climate change on the incidence of malaria suggests a widespread increase of risk due to expansion of the areas suitable for malaria transmission. The predicted increase is most pronounced at the borders of endemic malaria areas and at higher altitudes within malaria areas. The changes in malaria risk must be interpreted on the basis of local environment conditions, the effects of socioeconomic development and malaria control programs or capabilities. The incidence of infection is sensitive to climate changes in areas of Southeast Asia, South America and parts of Africa. In these areas the number of years of healthy life lost may increase significantly. End of series
NetMark: Public-Private Partnership For Sustainable Malaria Prevention Managed by the Academy for Educational Development (AED), a Washington, D.C.based nonprofit organization. Goal is to make affordable, lifesaving insecticide-treated nets commercially available on a national scale in Ghana, Nigeria, Senegal and Zambia. http://www.netmarkafrica.org/
Malaria Special - Main News Page swissinfo s malaria Special was awarded the prestigious Prix Italia for Web Another prize for the malaria Special, the Prix Italia 2004 prize for Web http://www.swissinfo.org/sen/swissinfo.html?siteSect=670
Malaria Mechanism Revealed By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for http://www.eurekalert.org/pub_releases/2005-07/cshl-mmr072505.php
Extractions: Cold Spring Harbor Laboratory By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. The findings are reported in the July 29 issue of the journal Cell. Malaria causes approximately 400 million clinical cases and 2 million deaths annually, with more than 80% of deaths occurring among children. The disease is caused by mosquito-borne parasites of the genus Plasmodium (primarily Plasmodium falciparum). Following the initial stages of infection, merozoite-stage parasites ("merozoites") invade red blood cells, leading to clinical symptoms and in many cases, death. "Niraj Tolia [the first author of the study] had malaria when he was young. So when he joined my lab as a graduate student, it didn't take long for me to convince him that this was a good project," says structural biologist Leemor Joshua-Tor of Cold Spring Harbor Laboratory, who led the research. A major pathway through which malaria parasites invade red blood cells is the binding of a protein on the surface of merozoites called EBA-175 to a receptor protein on the surface of red blood cells called glycophorin A. Merozoites die if they do not invade red blood cells soon after their release (from liver cells) into the bloodstream. Thus, the binding of EBA-175 to glycophorin A is a prominent target for the development of therapies to control malaria.
Malaria - MayoClinic.com malaria is one of the oldest diseases on Earth, but still one of its leading killers. http://www.mayoclinic.com/invoke.cfm?id=DS00475
Malaria Title Page WELCOME TO THE malaria WEBSITE MATERNAL malaria CEREBRAL malaria ANTIGENS COMMUNITY HEALTH VACCINES LINKS REFERENCES http://www.brown.edu/Courses/Bio_160/Projects1999/malaria/malmain.html
MalariaNet Sponsored by USAID's Office of Health, Infectious Diseases and Nutrition. Resources available include regular bulletins and reports outlining antimalaria strategies and policy recommendations, assessments of past programs, studies and conference proceedings. http://www.ehproject.org/Library/MalariaNet.htm
Extractions: Home This Is EHP EHP News EHP Activities ... Site Map EHP Malaria Reports Library Malaria Bulletins - 2004 EHP Info Center Malaria Bulletins - 2004/2003 EHP II Malaria and Other Vector-borne Disease Reports June 17, 2004 (pdf) May 20, 2004 (pdf) Apr 13 (pdf) Feb 2 (pdf) Jan 19-Feb 2004 (pdf) Jan 1-18, 2004 (pdf) Dec 15-28 (pdf) Dec 1-14 (pdf) Nov 17-30 (pdf) Nov 1-16 (pdf) Oct 20-31 (pdf) Oct 6-19 (pdf) Sep 22-Oct 5 (pdf) Sep 8-21 (pdf) Aug 25-Sep 7 (pdf) Aug 4-24 (pdf) July 21-Aug 3 (pdf) July 1-20 (pdf) June 16-30 (pdf) June 2-15 (pdf) Activity Report 137. Combining Hygiene Behavior Change with Water and Sanitation: Monitoring Progress in Hato Mayor, Dominican Republic Activity Report 136. Intercountry Collaboration for Improving Surveillance and Control of Vector-borne Diseases Activity Report 131.
EMVI Home Page Established in 1998 by the European Commission and interested European Union Member States, in order to address identified structural deficiencies in public http://www.emvi.org/
MIMCom Malaria Research Resources Communications working group of the Multilateral Initiative on malaria, from the National Library of Medicine. http://www.mimcom.net/
Extractions: Skip to Content Search NLM Web Site NLM Home Contact NLM Site Map FAQs MIMCom Malaria Research Resources MIMCom Home About Us Contact Us MIMCom Site Map ... MIMCom "We must develop a communications system so that the miraculous triumphs of modern science can be taken from the laboratory and transmitted to all in need." Senator Lister Hill, 1965 About MIMCom News and New Resources
BUBL LINK: Malaria Resource type index; malaria Database Information for scientists working in Includes malaria genome mapping data, nucleotide and protein information, http://bubl.ac.uk/link/m/malaria.htm
Extractions: BUBL LINK Catalogue of Internet Resources Home Search Subject Menus Countries ... Z Titles Descriptions Epidemiology, the Internet and Global Health GP Online Insects on WWW: Mosquito Malaria Database ... OMNI Subject Listing for Communicable Diseases Comments: bubl@bubl.ac.uk Online course designed to provide an overview on epidemiology and the Internet for medical and health related students around the world. The course consists of a series of annotated slide based lectures on topics such as disease monitoring, health economics, malaria, nutrition and global health.