World Jewish Congress Online Articles Urgent Medical Albumin is used as a Volume Expander in hypovolemia and shock syndrome Lyell s syndrome (toxic epidermal necrolysis); nephrotic syndrome; nephritis; http://www.worldjewishcongress.org/nfo/article.cfm?id=2751
Lamotrigine Rarely, serious skin rashes, including StevensJohnson syndrome and toxic epidermalnecrolysis (Lyell s syndrome) have been reported. http://www.mentalhealth.com/drug/p30-l06.html
Extractions: September 1999 Antiepileptic Lamotrigine is a drug of the phenyltriazine class chemically unrelated to existing antiepileptic drugs (AEDs). Lamotrigine is thought to act at voltage-sensitive sodium channels to stabilize neuronal membranes and inhibit the release of excitatory amino acid neurotransmitters (e.g. glutamate, aspartate) that are thought to play a role in the generation and spread of epileptic seizures. Clinical Trials: In placebo-controlled clinical studies, lamotrigine has been shown to be effective in reducing seizure frequency and the number of days with seizures when added to existing antiepileptic drug therapy in adult patients with partial seizures, with or without generalized tonic-clonic seizures, that are not satisfactorily controlled. Studies have also been conducted using lamotrigine monotherapy in patients (n=443) newly diagnosed with epilepsy (partial seizures, with or without secondary generalization or primary generalized tonic clonic). Results have shown comparable efficacy (time to first seizure, seizure frequency, percentage of patients seizure-free) with fewer side effects than currently approved therapies. Clinical trials have also demonstrated that patients (any seizure type) can be converted to lamotrigine monotherapy from polytherapy with significant numbers of patients maintaining or improving seizure control. Efficacy was maintained during longterm treatment (up to 152 weeks).
The EOPS Source Index 1992 9225 Stefani FH Strampelli s keratoprosthesis in corneal scarring fromLyell s syndrome (toxic epidermal necrolysis); 92-26 Balestrazzi E First http://www.helsinki.fi/laak/silk/perus/EOPS1992.html
Extractions: Go to Home Previous Next 60's ... Notes Streeten B W Invasive squamous carcinoma of the cornea: a 20 year incubation period Witschel H Bilateral xanthogranuloma of orbit and lid in an adult Adenoid cystic carcinoma Sahel J A Primary orbital melanoma D'Hermies F D Orbital involvement by an ethmoidal carcinoma Mullaney J Panuveal neurofibromatosis de Wolff-Rouendaal D Choroidal melanoma growing in a choroidal naevus in a patient with dysplastic naevus syndrome McCartney A C E Familial malignant melanoma of the uvea and p53 (a Victorian melodrama in four acts) Daicker B Pleomorphic adenocarcinoma of the ciliary epithelium Naumann G O H Melanocytoma of the ciliary body with extrascleral extension Hanssens M Medullo-epitheliomatous (?) structures in a congenitally blind eye Tarkkanen A Hereditary vitreoretinal degeneration (Wagner's disease) Libert J Ultrastructural studies of the vitreous in progressive retinoschisis Kennedy S Retinitis pigmentosa in hypobetalipoproteinemia (atypical retinitis pigmentosa with basal linear deposits) Ohnishi Y A case of cancer-associated retinopathy Garner A Drusen with calcification and secondary neovascularisation Vogel M H Retinoblastoma in a 12 year old boy Uffer S Retinal tumor in a member of a retinoblastoma family Neoplastic or nodular reactive proliferation of RPE Nicolaissen B Jr The morphology of one week old laser lesions in human retina
The EOPS Author Index - S additional tooth and cervical cyst; 9225 Strampelli s keratoprosthesis incorneal scarring from Lyell s syndrome (toxic epidermal necrolysis) http://www.helsinki.fi/laak/silk/perus/EOPSAUTS.html
Extractions: Strasbourg, France Unusual localized retinal gliosis Unilateral benign medulloepithelioma associated with bilateral retinal detachment Metastatic orbital neuroblastoma Vitreous metastasis from cutaneous melanoma Primary orbital melanoma Orbital nodular fasciitis? Orbital Kaposi sarcoma: an unusual location
Galen's Log: A Risk Free Society StevensJohnson syndrome, alopecia, exfoliative dermatitis, Lyell s syndrome (toxicepidermal necrolysis), photosensitivity reactions. http://galenslog.typepad.com/galens_log/2005/02/a_risk_free_soc.html
Extractions: hostName = '.typepad.com'; Main One of the TV networks ran a tragic story about 2 young girls who developed Stevens Johnson sydrome after taking ibuprofen over the counter. One died, the other lost her eyesight. These stories serve as grim reminders about the dual nature of any medications, both prescription and non prescription. Adverse reactions abound in almost any type of medication. Let's take a look at ibuprofen in the PDR: CONTRAINDICATIONS MOTRIN should not be used in patients with previously demonstrated hypersensitivity to ibuprofen, or in individuals with a history of allergic manifestations to aspirin or other NSAIDs. Severe anaphylactic-like reactions to ibuprofen have been reported in such patients, some with fatal outcome. INCIDENCE LESS THAN 1% Causal Relationship Unknown: The following adverse reactions occurred at an incidence of less than 1% in clinical trials, or were suggested by marketing experience under circumstances where a causal relationship could not be definitely established. They are listed as alerting information for the physician. Allergic: Serum sickness, lupus erythematosus syndrome, Henoch-Sch[omacr ]nlein vasculitis, angioedema. Cardivascular system: Arrhythmias (sinus tachycardia, sinus bradycardia). Hematologic system: Bleeding episodes (e.g., epistaxis, menorrhagia). Metabolic/endocrine: Gynecomastia, hypoglycemic reaction, acidosis. Nervous system: Paresthesias, hallucinations, dream abnormalities, pseudo-tumor cerebri. Special senses: Conjunctivitis, diplopia, optic neuritis, cataracts.
Pediatrics -- Sign In Page No cases of Lyell s syndrome or StevensJohnson syndrome were observed.Eighteen children were admitted to a hospital, 17 were seen in emergency departments http://pediatrics.aappublications.org/cgi/content/full/peds.2004-0040v1
Extractions: This Article Abstract Full Text (PDF) P ... Alert me if a correction is posted Services E-mail this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Sturkenboom, M. Related Collections
: The AMEDEO Literature Guide Novel treatments for druginduced toxic epidermal necrolysis (Lyell s syndrome).Int Arch Allergy Immunol 2005;136205-16. PubMed Related articles Abstract http://www.amedeo.com/medicine/hys/intaaimm.htm
Virtual Hospital: P & T News Injection site pain, pruritis, rash; Urticaria, ecchymosis, bruising, hematoma,tingling, Lyell s syndrome, StevensJohnson syndrome, exfoliative dermatitis http://www.vh.org/adult/provider/pharmacyservices/PTNews/1994/05.94.html
Extractions: Ketorolac is a potent inhibitor of the cyclo-oxygenase pathway of arachidonic acid metabolism, resulting in a decrease in prostaglandin and thromboxane products as shown in Figure 1.(2,3) It is structurally and pharmacologically related to tolmetin, zomepirac, and indomethacin.(4) It is structurally and pharmacologically related to tolmetin, zomepirac, and indomethacin.(4) Ketorolac exhibits analgesic, anti-inflammatory, and antipyretic activity. Ketorolac may produce analgesia by inhibiting the synthesis of prostaglandins peripherally and possibly centrally, but does not appear to affect opiate receptors.(4,5) Figure 1: Metabolism of Phospholipid and Arachidonic Acid Pharmacokinetic Properties Rapid and complete absorption occurs following intramuscular (IM) ketorolac administration, with a maximum plasma concentration achieved in 45 to 50 minutes. Ketorolac displays characteristics of a two-compartment model. In order to minimize the time delay in achieving adequate analgesic effect and to achieve steady state levels more rapidly, a loading dose equal to twice the maintenance dose is recommended.(5) Studies have shown a significant increase in plasma half-life and a decrease in total plasma clearance in the elderly,(6) and renally impaired(7) subjects compared with young volunteers. No changes occur in clearance with chronic dosing. Metabolism and excretion are outline in Table 1.(3-9)
MedlinePlus Medical Encyclopedia: Topics Beginning With Lo-Lz Loeffler s syndrome see Simple pulmonary eosinophilia (Loeffler s syndrome) Lye see Sodium hydroxide; Lyell s syndrome see Erythema multiforme http://www.nlm.nih.gov/medlineplus/ency/encyclopedia_Lo-Lz.htm
Extractions: Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Lobar intracerebral hemorrhage Lobar sclerosis see Pickâs disease Lobectomy see Lung surgery Lobster plant see Poinsettia Lobular capillary hemangioma see Pyogenic granuloma Lobular GN see Membranoproliferative GN I Localized lymphadenopathy see Lymphadenitis and lymphangitis Localized lymphadenopathy - armpit see Armpit lump Location of most skin cancers see Skin cancer locations Lockjaw see Tetanus Loeffler's syndrome see Simple pulmonary eosinophilia (Loeffler's syndrome) Lomotil overdose Long bones Loose bowel movements see Diarrhea Loose joints see Hypermobile joints Lorcet see Hydrocodone and acetaminophen overdose Lordosis Lortab see Hydrocodone and acetaminophen overdose Losing weight Losing weight with exercise Loss of a body part see Amputation - traumatic Loss of a child - resources Loss of a spouse - resources Loss of alertness see Consciousness - decreased Loss of appetite see Appetite - decreased Loss of balance see Dizziness Loss of bladder control see Urinary incontinence Loss of bowel control see Bowel incontinence Loss of consciousness - first aid see Unconsciousness - first aid Loss of coordination see Movement - uncoordinated Loss of hair see Hair loss Loss of hearing see Hearing loss Loss of memory see Memory loss Loss of movement see Muscle function loss Loss of sensation see Numbness and tingling Loss of smell see Smell - impaired Loss of taste see
Extractions: Press release concerning Lamictal (lamotrigine) and serious skin reactions Lamictal (lamotrigine) is a relatively new drug for the treatment of epilepsy. Skin reactions, especially at the beginning of treatment, are well known side effects with Lamictal. Therefore, a slow increase of the dose is important. Despite this, serious mucocutaneous reactions, such as febrile mucocutaneous syndrome (Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell's syndrome) have been observed. Warnings of these reactions are included in the product information for Lamictal. So far, 4 cases of serious skin reactions have been seen in Sweden in connection with Lamictal therapy. The Medical Products Agency is at present investigating these cases and the possible causal connection with Lamictal together with the company and the health personnel involved. Patients who are treated with Lamictal and who experience any skin reaction should interrupt the treatment and consult a physician. Otherwise, the patients should not on their own initiative stop treatment with Lamictal.
Science -- Sign In Toxic epidermal necrolysis (TEN, Lyell s syndrome) is a severe adverse drugreaction in which keratinocytes die and large sections of epidermis separate http://www.sciencemag.org/cgi/content/full/282/5388/490
Extractions: You do not have access to this item: Full Text : Viard et al., Inhibition of Toxic Epidermal Necrolysis by Blockade of CD95 with Human Intr..., Science You are on the site via Free Public Access. What content can I view with Free Public Access If you have a personal user name and password, please login below. SCIENCE Online Sign In Options For Viewing This Content User Name Password this computer. Help with Sign In If you don't use cookies, sign in here Join AAAS and subscribe to Science for free full access. Sign Up More Info Register for Free Partial Access including abstracts, summaries and special registered free full text content. Register More Info Regain Access to a recent Pay per Article purchase Need More Help? Can't get past this page? Forgotten your user name or password? AAAS Members activate your FREE Subscription
Dr. Koop - Erythema Multiforme Lyell s syndrome; StevensJohnson syndrome; Toxic epidermal necrolysis Stevens-Johnson syndrome and toxic epidermal necrolysis are associated with high http://www.drkoop.com/ency/93/000851trt.html
Dr. Koop - Erythema Multiforme Lyell s syndrome; StevensJohnson syndrome; Toxic epidermal necrolysis Raynaud s Disease, Respiratory, Reye syndrome, Rheumatoid Arthritis http://www.drkoop.com/ency/93/000851prv.html
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Extractions: "You can change any thing in this country" Emergency Zone : Blood Bank Eye Bank Ambulance 24 Hours Clinic ... Disease Info : L A B C D ... Z Labyrinthitis Lack of intrinsic factor Lacrimal gland tumor Lactase deficiency Lactic acidosis Lactose intolerance Laennec's cirrhosis Lambert-Eaton Syndrome Lamellar ichthyosis Lancefield group B streptococcus Landry-Guillain-Barre syndrome Langerhans cell histiocytosis Language disorder - expressive Larva migrans visceralis Laryngeal cancer Laryngeal nerve damage Laryngitis Late persistent Lyme disease Late syphilis Lateral epicondylitis Lateral rectus palsy Lazy eye Lead poisoning disease LeFort injuries Left-sided heart failure Legg-Calve-Perthes disease Legionella pneumonia Legionnaire's disease Leiomyoma Leiomyoma - intestine Leiomyosarcoma Leishmaniasis Lens opacity Lentigos Leopard syndrome Leprosy Leptospirosis Lesch-Nyhan syndrome Lethal midline granuloma Letterer-Siwe disease Leukemia Leukemic reticuloendotheliosis Leukemoid reaction Leukoplakia Leydig cell tumor LGV Lice - body Lice - head Lice - pubic Lichen planus Lichen simplex chronicus Limb-girdle muscular dystrophies Lipid Disorders - acquired Lipofuscinosis Lipoid nephrosis Listeriosis Little stroke Livedo reticularis Liver abscess Liver cancer Liver cirrhosis Liver disease Liver disease due to alcohol Liver hemangioma Liver metastases Liver spots Lobar intracerebral hemorrhage Lobar sclerosis Lobular capillary hemangioma Lobular GN Localized lymphadenopathy Lockjaw Loeffler's syndrome Lou Gehrig's disease Louis-Bar syndrome Low blood magnesium Low blood phosphate
BARTTERSITE.COM Meniere s Disease Rett syndrome Raynaud Asperger s syndrome Treatment Steven Johnson syndrome Lyell s syndrome http://www.barttersite.com/gitelman.htm
Stevens-Johnson Syndrome Information Diseases Database Erythema multiforme aka/or Lyell s disease aka/or Scalded skin syndrome. may becaused by or feature of + (Follow link for list. http://www.diseasesdatabase.com/ddb4450.htm
Extractions: Scalded skin syndrome Stevens-Johnson syndrome: Definition(s) via UMLS Code translations and terms via UMLS Stevens-Johnson syndrome: specific web sites Send Stevens-Johnson syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these:
Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Infectious Diseases Last Updated: June 13, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: TEN, Lyell's disease, mucocutaneous exfoliative disease, erythema multiforme, EM, bullous erythema multiforme, Stevens-Johnson syndrome, SJS, mucocutaneous reaction, widespread erythema, necrosis, bullous detachment of the epidermis, SJS-TEN, TEN with spots, TEN without spots AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Gregory P Garra, DO , Clinical Assistant Professor of Emergency Medicine, Stony Brook University School of Medicine; Program Director, Department of Emergency Medicine, Stony Brook University Hospital Coauthor(s): Peter Viccellio, MD , Vice-Chair, Professor, Department of Emergency Medicine, State University of New York at Stony Brook Gregory P Garra, DO, is a member of the following medical societies:
Bextra Erytherma Multiforme Toxic epidermal necrolysis (TEN syndrome, or Lyell s syndrome) involves multiplelarge blisters (bullae) that coalesce, followed by sloughing of all or most http://www.wrongful-death.com/wrongful_death_lawyer/bextra-multiforme.html
Extractions: Your Email Address: BREAKING NEWS: 11-10-04 - BEXTRA MORE THAN DOUBLES RISK OF HEART ATTACK - This week, researchers said a preliminary study indicated that Bextra, a painkiller in the same class as Vioxx, more than doubled the risk of heart attack. Bextra has also been linked to strokes, heart disease, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis and erythema multiforme. Click Here for more information regarding Bextra. Erythema multiforme is a skin disorder resulting from an allergic reaction. Erythema multiforme is a type of hypersensitivity (allergic) reaction that occurs in response to medications, infections, or illness. Medications associated with erythema multiforme include sulfonamides, penicillins, barbiturates, and phenytoin. Associated infections include herpes simplex and mycoplasma infections. The exact cause has been attributed to0 the use of Bextra. The disorder is believed to involve damage to the blood vessels of the skin with subsequent damage to skin tissues. Approximately 90% of erythema multiforme cases are associated with herpes simplex or Mycoplasma infections. The disorder occurs primarily in children and young adults.
