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Kernicterus:     more detail

Haemorrhagic and Haematological Disorders of Fetus and Newborn: Neonatal Jaundice, Polycythemia, Kernicterus, Haemorrhagic Disease of the Newborn Bilirubin guideline stresses increased awareness: would prevent kernicterus.(Clinical Rounds): An article from: Pediatric News by Norra MacReady, 2004-08-01 KERNICTERUS. Report based on a symposiun held at the IX INTERNATIONAL CONGRESS OF PAEDIATRICS, Montreal, July 1959. by Andrew Sass-Lortsak, 1961 Kernicterus: Webster's Timeline History, 1937 - 2007 by Icon Group International, 2009-04-16 LETTERS.(The Real Cause of Kernicterus)(Just Walk On Out)(Tedious Committee Meetings)(Letter to the Editor): An article from: Pediatric News Kernicterus (Contemporary Clinical Neuroscience) by David W. McCandless, 2010-09-09 Pathology of Kernicterus and Posticteric Encephalopathy: Presentation of 87 Cases, with a Consideration of Pathogenesis and Etiology (AMAERICAN ACADEMY FOR CEREBRAL PALSY) by WEBB HAYMAKER, 1961 AAP Is Revising Hyperbilirubinemia Guidelines.: An article from: Pediatric News by Sally Koch Kubetin, 2001-10-01 Investigational drug looks good for hyperbilirubinemia: FDA panel debate.(Children's Health)(stannsoporfin): An article from: Family Practice News by Michele G. Sullivan, 2004-02-15 Screen doesn't prevent bilirubin encephalopathy.(CLINICAL ROUNDS): An article from: Family Practice News by Mary Ellen Schneider, 2009-10-15 Panel looks at chronic bilirubin encephalopathy.(CLINICAL ROUNDS): An article from: Pediatric News by Mary Ellen Schneider, 2009-10-01 Cry analysis in infants with Rh haemolytic disease (Acta paediatrica Scandinavica) by Maila Koivisto, 1987

lists with details

41. Kernicterus - Patient UK
    kernicterus Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information.  
    http://www.patient.co.uk/showdoc/40000455/
    
    Extractions: PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Bilirubin encephalopathy It is a complication of neonatal jaundice . The word kernicterus means yellow kern, kern being the structures of the brain that are most commonly affected. They are the basal ganglia, hippocampus, geniculate bodies and cranial nerve nuclei, especially the oculomotor, vestibular, and cochlear. The cerebellum can also be affected. At postmortem examination a characteristic yellow stain is seen in those structures. Acute bilirubin encephalopathy is the clinical manifestation of bilirubin toxicity. There is hypotonia followed by hypertonia, opisthotonus (backward arching of the neck), or retrocollis (backward arching of the back) or both. It is taken as synonymous with kernicterus. Much of the traditional teaching about neonatal jaundice and kernicterus has been revised. It is the premature baby who is at risk and kernicterus rarely affects a term infant unless bilirubin levels are exceptionally high. A high level of physiological jaundice, especially in breast fed babies, seems benign and resolves spontaneously without complications. Epidemiology: Kernicterus occurs in all part of the world but is more frequent where G6PD deficiency is common. Numbers fell in the 1970s and 1980s only to rise again in the 1990s.

42. ► Rh Incompatibility
    kernicterus; Rhinduced hemolytic disease of the newborn; Hydrops fetalis Hydrops fetalis and kernicterus have decreased markedly in frequency as a  
    http://www.umm.edu/ency/article/001600.htm
    
    Extractions: Causes, incidence, and risk factors: During pregnancy , red blood cells from the fetus can get into the mother's bloodstream as she nourishes her child through the placenta. If the mother is Rh negative, her system cannot tolerate the presence of Rh positive red blood cells. In such cases, the mother's immune system treats the Rh positive fetal cells as if they were a foreign substance and makes antibodies against the fetal blood cells. These anti-Rh antibodies may cross the placenta into the fetus, where they destroy the fetus' circulating red blood cells. First-born infants are often not affected (unless the mother has had previous miscarriages/abortions, which could have sensitized her system) as it takes time for the mother to develop antibodies against the fetal blood. However, second children who are also Rh-positive may be harmed.

43. Pediatric Pathology
    The yellow staining in the brain of a neonate is known as kernicterus. Increased unconjugated bilirubin, which accounts for the kernicterus,  
    http://www-medlib.med.utah.edu/WebPath/PEDHTML/PED242.html
    
    Extractions: The yellow staining in the brain of a neonate is known as kernicterus. There is a coronal section of medulla on the left and cerebral hemisphere on the right demonstrating kernicterus in deep grey matter of hemisphere and brain stem. Increased unconjugated bilirubin, which accounts for the kernicterus, is toxic to the brain tissue. Kernicterus is more likely to occur with prematurity, low birth weight, and increased bilirubin levels.

44. Definition Of Kernicterus - WordReference.com Dictionary
    kernicterus Definition from dictionary. 1, kernicterus. an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow  
    http://www.wordreference.com/definition/kernicterus

45. Kernicterus
    kernicterus is a rare neurological disorder characterized by excessive levels of bilirubin in the blood (hyperbilirubinemia) during infancy.  
    http://www.bchealthguide.org/kbase/nord/nord233.htm
    
    Extractions: It is possible that the main title of the report Kernicterus is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Kernicterus is a rare neurological disorder characterized by excessive levels of bilirubin in the blood (hyperbilirubinemia) during infancy. Bilirubin is an orange-yellow bile pigment that is a byproduct of the natural breakdown of hemoglobin in red blood cells (hemolysis). Toxic levels of bilirubin may accumulate in the brain, potentially resulting in a variety of symptoms and physical findings. These symptoms may include lack of energy (lethargy), poor feeding habits, fever, and vomiting. Affected infants may also experience the absence of certain reflexes (e.g., Moro reflex, etc.); mild to severe muscle spasms including those in which the head and heels are bent backward and the body bows forward (opisthotonus); and/or uncontrolled involuntary muscle movements (spasticity). In some cases, infants with kernicterus may develop life-threatening complications. March of Dimes Birth Defects Foundation

46. Kernicterus News - Healthcare Industry Today
    kernicterus. Service for healthcare industry professionals and analysts. Constantly updated news and information about kernicterus.  
    http://www.healthcareindustrytoday.com/news/Kernicterus
    
    Extractions: Sign up for this newsletter Manage newsletter(s) Make a new newsletter Send page to a friend ... Staff Health Sections: Front Page Latest News Industry Insurance Regulation Drugs Cancer Disease Nutrition Aging Health A-Z Index Cancer Cancer Centers Diabetes Digestive System Drugs H O T - T O P I C S Illicit Drugs Infectious Diseases Medicaid Medicare Mental Health Pharmaceutical Companies Sexual Health Sleep Disorders News by Country/State: Afghanistan Alabama Alaska Albania Algeria Angola Argentina Arizona Arkansas Armenia Australia Austria Azerbaijan Bahrain Balkans Bangladesh Barbados Belarus Belgium Bermuda Bolivia Bosnia Botswana Brazil Bulgaria Burundi California Cambodia Cameroon Canada Central African Republic Central Europe Chile China Colombia Colorado Congos Connecticut Costa Rica Cote d Ivoire Croatia Cuba Cyprus Czech Republic Delaware Denmark Dominican Republic East Timor Ecuador Egypt Eritrea Estonia Ethiopia Falkland Islands Finland Florida France Gambia Georgia Georgia (U.S.) Germany Ghana Greece Guatemala Guyana Haiti Hawaii Honduras Hong Kong Hungary Iceland Idaho Illinois India Indiana Indonesia Iowa Iran Iraq Ireland Israel Italy Jamaica Japan Jordan Kansas Kazakhstan Kentucky Kenya Kuwait Kyrgyzstan Laos Latvia Lebanon Lesotho Liberia Libya Lithuania Louisiana Luxembourg Macedonia Madagascar Maine Malawi Malaysia/Brunei Mali Malta Maryland Massachusetts Mexico Michigan Minnesota Mississippi Missouri Moldova Mongolia Montana Morocco Mozambique Myanmar Namibia Nebraska Nepal/Bhutan Netherlands Nevada New Hampshire New Jersey New Mexico New York New Zealand Nicaragua Nigeria North Carolina North Dakota North Korea Norway Oceania

47. Kernicterus - Information & News
    Early postpartum visits with pediatricians may help prevent a dangerous complication associated with jaundice, according to the presentation, ?  
    http://www.news-medical.net/?keyword=Kernicterus

48. Kernicterus Lawsuit Overview - Find Trial Lawyers And Attorneys With Experience
    kernicterus Overview - Find Trial Lawyers and Attorneys with Experience in kernicterus Personal Injury Law. Contact an attorney who can help you protect  
    http://www.injuryboard.com/view.cfm/Topic=311
    
    Extractions: InjuryBoard.com September 9, 2005 An estimated 300,000 workplace injuries occur each year in the United States. Personal Injury Guidant Defibrillator Recall Vioxx / Rofecoxib Celebrex / Celecoxib ... Children's Health Matters Kernicterus Overview If you or a family member has been injured, contact a personal injury attorney today. Just fill out InjuryBoard.com's on-line questionnaire and have a personal injury lawyer review your potential personal injury claim - free of charge. Ask an Attorney Kernicterus is a debilitating and potentially deadly condition that may appear in newborns. The condition typically occurs in infants suffering from jaundice . Jaundice affects the liver's ability to process bilirubin, a byproduct of red blood cell disposal. Excess bilirubin can accumulate in the brain causing Kernicterus. The condition is characterized by drowsiness , vomiting, feeding problems, neck and back spasms, rolling of the eyes, mental retardation cerebral palsy hearing problems vision problems and death.

49. Hill Health Topics A-Z - Kernicterus
    kernicterus. National Organization for Rare Disorders. Important It is possible that the main title of the report kernicterus is not the name you expected.  
    http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord233&SE

50. Kernicterus
    what is kernicterus, definition of kernicterus,kernicterus.  
    http://www.english-dictionary.us/meaning/kernicterus.asp

51. HON - News : Health Tip: Does Your Newborn Have Kernicterus?
    kernicterus, left untreated, can lead to brain damage, cerebral palsy and hearing loss, the CDC says. It also can cause vision problems and mental  
    http://www.hon.ch/News/HSN/521324.html
    
    Extractions: Symptoms include yellowing of the skin and eyes (HealthDayNews) Lots of babies are born with jaundice, indicated by a yellowing of the skin and the whites of the eyes. The condition is normally caused by overproduction of a substance produced by the liver called bilirubin. In most cases, the jaundice quickly goes away by itself. But if the infant's color grows too yellow or doesn't go away, it could indicate a serious condition called kernicterus, the U.S. Centers for Disease Control and Prevention says. Kernicterus, left untreated, can lead to brain damage, cerebral palsy and hearing loss, the CDC says. It also can cause vision problems and mental retardation. If you're concerned about your newborn's jaundice, contact your pediatrician. ScoutNews LLC Resources from HONselect HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.

52. Kernicterus Is Damage To The Brain Centers Of Infants Caused By Jaundice
    kernicterus is damage to the brain centers of infants caused by jaundice. Newborn babies are often polycythemic , meaning they have too many red blood  
    http://www.krctraining.com/CRA Definitions/kernicterus.htm
    
    Extractions: In adults and older children, jaundice is harmless in and of itself. But the tissues protecting the brain (the blood-brain barrier) are immature in newborns. The bilirubin penetrates the brain, and literally stains the nerve bodies, causing irreversible damage. Depending on the level of exposure, the effects range from unnoticeable to severe brain damage.

53. Unbound Bilirubin In A Term Newborn With Kernicterus -- Ahlfors And Herbsman 111
    Unbound Bilirubin in a Term Newborn With kernicterus. Charles E. Ahlfors, MD and Oded Herbsman, MD. Department of Pediatrics  
    http://pediatrics.aappublications.org/cgi/content/extract/111/5/1110

54. Hyperbilirubinemia And Kernicterus: 50 Years Later -- Ip Et Al. 114 (1): 263 --
    The authors further reported that kernicterus did not occur in 200 Indirect evidence from the decreasing prevalence of kernicterus since the  
    http://pediatrics.aappublications.org/cgi/content/full/114/1/263
    
    Extractions: ISI Web of Science (2) PubMed PubMed Citation Articles by Ip, S. Related Collections Office Practice PEDIATRICS Vol. 114 No. 1 July 2004, pp. 263-264 Abbreviations: TSB, total serum bilirubin In 1952, Hsia et al reported that 50% of infants with erythroblastosis developed kernicterus. The authors further reported that kernicterus fetalis when the hospital policy was to keep the serum bilirubin been proved that bilirubin is the actual cause of brain damage, tests of serum bilirubin in infants with erythroblastosis fetalis serve as extremely valuable guides to treatment." There is no doubt that bilirubin plays a major role in the development of central nervous system pathology. High-quality studies

55. Kernicterus - Definition From Biology-Online.org
    Definition and other additional information on kernicterus from BiologyOnline.org dictionary.  
    http://www.biology-online.org/dictionary/kernicterus
    
    Extractions: Directory ... K kernicterus (Science: paediatrics) Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage . The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected , it is also called bilirubin encephalopathy

56. 2003 Federal/State Partnership Meeting - Hot Topics - Kernicterus
    President, Parents of Infants Children with kernicterus (PICK) Textonly Transcript. spacer, spacer, spacer. spacer, spacer, spacer  
    http://www.cademedia.com/archives/mchb/partnership2003/hottopic_kernicterus.htm

57. Log In Problems
    Care related to the management of neonatal hyperbilirubinemia should be based on three fundamental principles (1) evidencebased practice,  
    http://www.medscape.com/viewarticle/497029

58. Log In Problems
    This report underscores that to prevent kernicterus, newborns must be screened and promptly treated for hyperbilirubinemia.  
    http://www.medscape.com/viewarticle/414615

59. Pediatrics Hyperbilirubinemia And Kernicterus 50 Years Later
    Full text of the article, Hyperbilirubinemia and kernicterus 50 years later from Pediatrics, a publication in the field of Health Fitness,  
    http://www.findarticles.com/p/articles/mi_m0950/is_1_114/ai_n6110978

60. Nursing: Unwelcome Return For Kernicterus
    Full text of the article, Unwelcome return for kernicterus from Nursing, a publication in the field of Health Fitness, is provided free of charge by  
    http://www.findarticles.com/p/articles/mi_qa3689/is_200311/ai_n9324440
    
    Extractions: Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. NEONATAL JAUNDICE Because of shorter hospital stays for newborns, severe jaundice, which can cause hearing loss and brain damage or kernicterus, is going unnoticed in some infants. Caused by excess bilirubin in the blood, jaundice may not develop until several days after birth. About 60% of American newborns have jaundice, although many recover without treatment. But an accumulation of excess bilirubin is toxic to the brain.

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