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Kernicterus:     more detail

Bilirubin guideline stresses increased awareness: would prevent kernicterus.(Clinical Rounds): An article from: Pediatric News by Norra MacReady, 2004-08-01 KERNICTERUS. Report based on a symposiun held at the IX INTERNATIONAL CONGRESS OF PAEDIATRICS, Montreal, July 1959. by Andrew Sass-Lortsak, 1961 LETTERS.(The Real Cause of Kernicterus)(Just Walk On Out)(Tedious Committee Meetings)(Letter to the Editor): An article from: Pediatric News Pathology of Kernicterus and Posticteric Encephalopathy: Presentation of 87 Cases, with a Consideration of Pathogenesis and Etiology (AMAERICAN ACADEMY FOR CEREBRAL PALSY) by WEBB HAYMAKER, 1961 Investigational drug looks good for hyperbilirubinemia: FDA panel debate.(Children's Health)(stannsoporfin): An article from: Family Practice News by Michele G. Sullivan, 2004-02-15 AAP Is Revising Hyperbilirubinemia Guidelines.: An article from: Pediatric News by Sally Koch Kubetin, 2001-10-01 Cry analysis in infants with Rh haemolytic disease (Acta paediatrica Scandinavica) by Maila Koivisto, 1987

lists with details

1. Kernicterus
   Offers the pathophysiology, symptoms and signs and prognosis.  
   http://www.fpnotebook.com/NIC39.htm
   
   Extractions: Home About Links Index ... Editor's Choice document.write(code); Advertisement Neonatology Gastroenterology Assorted Pages Jaundice in Newborns Breast Feeding Jaundice Neonatal Jaundice Causes Nonphysiologic Neonatal Jaundice ... Hepatomegaly in Newborns Kernicterus Bilirubin Toxicity Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Practice Management Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Neonatology Index Birth Dermatology Otolaryngology Examination Ophthalmology Fluids, Electrolytes, and Nutrition Gastroenterology Hematology and Oncology Infectious Disease Laboratory General Pulmonology Neurology Orthopedics Pharmacology Premature Surgery Page Gastroenterology Index Jaundice Jaundice Physiologic Breast Feeding Jaundice Causes Jaundice NonPhysiologic Jaundice Nonphysiologic Kernicterus Jaundice Management Exchange Transfusion Jaundice Management Phototherapy Umbilicus Umbilicus Granuloma Umbilicus Urachal Anomaly Pathophysiology Unconjugated Bilirubin (indirect) elevation Total Bilirubin Bilirubin necroses neurons Basal ganglia Globus pallidus Putamen Caudate nuclei Symptoms and Signs Stage 1 Moro reflex diminished Tone diminished Lethargy Poor feeding Vomiting High pitched cry Stage 2 (High mortality in this stage) Opisthotonus

2. NORD - National Organization For Rare Disorders, Inc.
   Offers synonyms, a general discussion and further resources.  
   http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Kernicterus

3. MedlinePlus Medical Encyclopedia: Rh Incompatibility
   An extensive look at kernicterus, including a description, the causes, incidence and risk factors.  
   http://www.nlm.nih.gov/medlineplus/ency/article/001600.htm
   
   Extractions: @import url(/medlineplus/images/advanced.css); Skip navigation Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Contents of this page: Erythroblastosis fetalis, photomicrograph Jaundice infant Antibodies Exchange transfusion - series Alternative names Return to top Rh-induced hemolytic disease of the newborn; Hydrops fetalis Definition Return to top Rh incompatibility is a condition which develops when a pregnant woman has an Rh-negative blood type and the fetus she carries has Rh-positive blood type. Causes, incidence, and risk factors Return to top During pregnancy, red blood cells from the fetus can get into the mother's bloodstream as she nourishes her child through the placenta. If the mother is Rh-negative, her system cannot tolerate the presence of Rh-positive red blood cells. In such cases, the mother's immune system treats the Rh-positive fetal cells as if they were a foreign substance and makes antibodies against the fetal blood cells. These anti-Rh antibodies may cross the placenta into the fetus, where they destroy the fetus's circulating red blood cells.

4. Kerniterus, NCBDDD,CDC
   kernicterus is a preventable lifelong disability. Any baby with jaundice is at risk for kernicterus, but proper management and treatment can prevent this  
   http://www.cdc.gov/node.do/id/0900f3ec80006a5c
   
   Extractions: Cal Sheridan's Story My son, Cal, was born a healthy baby boy on March 23, 1995 in a large accredited hospital that delivers over 5500 newborns a year. Cal was first noted to be jaundiced through visual assessment at 16.5 hours old, but a bilirubin test was not done. More... Cal's thoughts on kernicterus: I’m mad at all the mistakes on all these babies. Cal age 9 A Mother's Scientific Perspective: Living with Kernicterus by Karen Dixon (PDF Document) Health Care Professional Information High levels of bilirubin are toxic to the developing newborn's central nervous system. In full term infants, acute symptoms of severe hyperbilirubinemia include extreme jaundice and neurologic abnormalities in level of consciousness, tone and movement, and brain stem function, particularly in relation to feeding and crying.

5. General Information About Kernicterus, NCBDDD, CDC
   kernicterus is a type of brain damage that causes athetoid cerebral palsy and hearing loss. It also causes problems with vision and teeth and  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Kernicterus En Español, NCBDDD, CDC
   Translate this page kernicterus is a type of brain damage that causes athetoid cerebral palsy and hearing loss. It also causes problems with vision and teeth and sometimes can  
   http://www.cdc.gov/ncbddd/dd/spkernicterus.htm
   
   Extractions: Kernicterus es un tipo de daño cerebral que causa parálisis cerebral atetoide y pérdida de la audición. También causa problemas de la visión y la dentadura, y a veces puede producir retardo mental. En algunos recién nacidos, el hígado fabrica demasiado pigmento amarillo llamado bilirrubina. Cuando se produce demasiada concentración de bilirrubina en el cuerpo de un recién nacido, la piel y la parte blanca de los ojos se vuelven amarillentos. Esta coloración se denomina ictericia. La ictericia es muy común en los recién nacidos y por lo general desaparece sola. Un poco de ictericia no presenta problema, pero algunos bebés tienen demasiada ictericia. Si no reciben tratamiento, los elevados niveles de bilirrubina pueden dañar el cerebro. ¿Quién puede contraer kernicterus? Cualquier bebé que no ha recibido tratamiento contra la ictericia corre el riesgo de contraer kernectirus. Esto no significa que todos los niños con piel amarillenta presenten daño cerebral. Gran parte de los bebés con ictericia se recuperan solos. Si su piel está muy amarillenta, podrían necesitar tratamiento de fototerapia. Si la fototerapia no disminuye los niveles de bilirrubina del bebé, éste puede necesitar una transfusión.

7. Kernicterus In Full-Term Infants - United States, 19941998
   kernicterus in FullTerm Infants - United States, 19941998  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Kernicterus & Newborn Jaundice
   kernicterus is from the Greek kern or kernal plus icterus or yellow. Clinically, classic kernicterus involves 1) specific movement disorder,  
   http://www.kernicterus.org/
   
   Extractions: Introduction: Jaundice and Kernicterus Jaundice About 60% of newborn infants in the United States are jaundiced, that is they look yellow. Jaundice is the yellow coloring of the skin and other tissues. Jaundice can often be seen well in the sclera, the "whites" of the eyes, which look yellow. Many many babies look jaundiced (60%), but they are not deeply jaundiced, not jaundiced below the abdomen, and they act OK - they nurse, they aren't too sleepy, they have normal muscle tone, their cry is normal, they don't arch their backs. Kernicterus Information for Parents: The Jaundiced Baby Jaundice in Newborns and its Treatment About 60% of newborn infants in the United States are jaundiced, that is they look yellow. Excessive jaundice in newborn infants may cause brain damage. Jaundice is caused by a high level of bilirubin in the blood (hyperbilirubinemia) and tissues. When bilirubin gets too high it can be treated. Norms exist for bilirubin in term and nearly term babies based on the age in hours after birth. Other factors, such as prematurity, blood group incompatibilities between infant and mother including Rh and ABO blood types, and bruising, especially cephalohematomas and caputs, can increase bilirubin production and lead to excessive jaundice.

9. MedlinePlus Medical Encyclopedia Rh Incompatibility
   An extensive look at kernicterus, including a description, the causes, incidence and risk factors.  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. EMedicine - Kernicterus : Article By Shelley C Springer, MD, MBA, MSc
    kernicterus Traditionally, the term kernicterus (literally yellow kern, with kern indicating the most commonly afflicted region of the brain, ie,  
    http://www.emedicine.com/ped/topic1247.htm
    
    Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Neonatology Last Updated: November 6, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: acute bilirubin encephalopathy, chronic postkernicteric bilirubin encephalopathy, chronic bilirubin encephalopathy, profound pathologic hyperbilirubinemia AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Shelley C Springer, MD, MBA, MSc , Neonatologist, Assistant Professor of Pediatrics, Department of Pediatrics, University of Wisconsin, Madison Coauthor(s): David J Annibale, MD , Director of Fellowship Training Program in Neonatal-Perinatal Medicine, Associate Professor, Department of Pediatrics, Medical University of South Carolina Shelley C Springer, MD, MBA, MSc, is a member of the following medical societies: American Academy of Pediatrics American Medical Association Minnesota Medical Association National Perinatal Association , and South Carolina Medical Association Editor(s): Oussama Itani, MD

11. Sentinel Event Alert, Issue 18 - April 2001
    kernicterus threatens healthy newborns kernicterus is a condition of newborns that leads to severely disabling brain damage or death.  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. P.I.C.K. - Parents Of Infants And Children With Kernicterus
    kernicterus is a preventable neurologic disorder caused by newborn jaundice that can result in cerebral palsy, auditory processing problems (AN),  
    http://www.pickonline.org/

13. Kernicterus PICK Online
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. P.I.C.K. - PICK Community - Kernicterus Study
    The kernicterus Registry help track the number of children with a If you know a child with kernicterus or are interested in this study, please contact  
    http://www.pickonline.org/community/4/
    
    Extractions: STAND UP AND BE COUNTED If you have a child or know a child who has neurological impairment due to severe newborn jaundice we urge you to contact Dr. Lois Johnson at JohnsonL@pahosp.com to be included in the Kernicterus Registry. The Kernicterus Registry help track the number of children with a bilirubin-induced injury. KERNICTERUS STUDY Karen Dixon, PhD and parent of a child with kernicterus, is conducting a study on physical symptoms in infants with kernicterus during the first year. The study also addresses the contributing factors or causes for the failure to identify infants at risk for severe hyperbilirubinemia. If you know a child with kernicterus or are interested in this study, please contact Karen Dixon at karendixon@pickonline.org.

15. Increased Vigilance Needed To Prevent Kernicterus In Newborns
    Increased vigilance needed to prevent kernicterus in newborns Lori O'Keefe Correspondent  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Tighter Monitoring Of Jaundice Urged By CDC
    kernicterus, a lifelong brain syndrome, can include cerebral palsy Why have more kernicterus cases come out?  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Kernicterus - Problems, Warning Signs And Treatment Options At MedicineNet.com
    Learn about kernicterus, brain damage in newborn babies, and jaundice, a yellowing of the skin.  
    http://www.medicinenet.com/kernicterus/article.htm
    
    Extractions: Printer-Friendly Format FREE Newsletters Email to a Friend ... Next What are some warning signs of kernicterus? Can jaundice be treated and prevent kernicterus from developing? What should I do if I think my baby has jaundice? Is there a support group for parents of children with kernicterus? What is kernicterus? Kernicterus is a type of brain damage that causes athetoid cerebral palsy and hearing loss. It also causes problems with vision and teeth and sometimes can cause mental retardation. In some newborn babies, the liver makes too much yellow pigment called bilirubin. When too much bilirubin builds up in a new baby's body, the skin and whites of the eyes turn yellow. This yellow coloring is called jaundice. Jaundice is very common in newborn babies and usually goes away by itself. A little jaundice is not a problem, but a few babies have too much jaundice. If not treated, high levels of bilirubin can damage the brain.  Who can develop kernicterus?

18. Kernicterus Newborn Jaundice
    Introduction Jaundice and kernicterus Jaundice kernicterus Brain Damage due to Excessive Jaundice  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Kernicterus - Problems, Warning Signs And Treatment Options At MedicineNet.com
    CPS CPSP Resource Article kernicterus and the healthy term newbornQuality information on children s health and wellbeing, such as vaccination, pregnancy, infant care, healthy eating, common illnesses, safety,  
    http://www.medicinenet.com/script/main/art.asp?articlekey=46852

20. CPS CPSP Resource Article Kernicterus And The Healthy Term Newborn
    kernicterus and the healthy term newborn kernicterus and bilirubin encephalopathy  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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