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Hyperhomocysteinemia:     more detail

Hyperhomocysteinemia: Webster's Timeline History, 1992 - 2007 by Icon Group International, 2009-02-20 Hyperhomocysteinemia as a result of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism causes an increased risk of cerebrovascular disease: ... An article from: Original Internist by Robert A., Jr. Duca, 2010-09-01 Hyperhomocysteinemia in end stage renal disease: is treatment necessary? (Continuing Education).: An article from: Nephrology Nursing Journal by Jennifer Snavely, 2002-04-01

lists with details

21. THE MERCK MANUAL, Sec. 11, Ch. 132, Thrombotic Disorders
    hyperhomocysteinemia. Plasma homocysteine levels are elevated tenfold or greater hyperhomocysteinemia is also strongly correlated with atherosclerotic  
    http://www.merck.com/mrkshared/mmanual/section11/chapter132/132a.jsp

22. Entrez PubMed
    Furthermore, we investigated the combined effect of hyperhomocysteinemia The prevalence of fasting hyperhomocysteinemia ( 14.0 micromol/L) was 25.8%.  
    http://www.nutritionandmetabolism.com/pubmed/9445267
    
    Extractions: My NCBI [Sign In] [Register] All Databases ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes Conserved Domains 3D Domains Gene Genome Project GENSAT GEO Profiles GEO DataSets HomoloGene Journals MeSH NCBI Web Site NLM Catalog OMIA OMIM PMC PopSet Probe PubChem BioAssay PubChem Compound PubChem Substance SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard Details About Entrez PubMed Central Display Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIA Links OMIM Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links Show Sort by Author Journal Pub Date Send to Text File Clipboard E-mail Order All: 1 Review: Arterioscler Thromb Vasc Biol.

23. Entrez PubMed
    hyperhomocysteinemia and the endocrine system implications for atherosclerosis and thrombosis. Fonseca V, Guba SC, Fink LM.  
    http://www.nutritionandmetabolism.com/pubmed/10529901
    
    Extractions: My NCBI [Sign In] [Register] All Databases ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes Conserved Domains 3D Domains Gene Genome Project GENSAT GEO Profiles GEO DataSets HomoloGene Journals MeSH NCBI Web Site NLM Catalog OMIA OMIM PMC PopSet Probe PubChem BioAssay PubChem Compound PubChem Substance SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard Details About Entrez PubMed Central Display Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIA Links OMIM Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links Show Sort by Author Journal Pub Date Send to Text File Clipboard E-mail Order All: 1 Review: 1 Endocr Rev.

24. Entrez PubMed
    hyperhomocysteinemia, atherosclerosis and thrombosis. Cattaneo M. Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Internal Medicine,  
    http://genomebiology.com/pubmed/10063987
    
    Extractions: My NCBI [Sign In] [Register] All Databases ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes Conserved Domains 3D Domains Gene Genome Project GENSAT GEO Profiles GEO DataSets HomoloGene Journals MeSH NCBI Web Site NLM Catalog OMIA OMIM PMC PopSet Probe PubChem BioAssay PubChem Compound PubChem Substance SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard Details About Entrez PubMed Central Display Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIA Links OMIM Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links Show Sort by Author Journal Pub Date Send to Text File Clipboard E-mail Order All: 1 Review: 1 Thromb Haemost.

25. Homocysteine
    had hyperhomocysteinemia were daily given 100 mcg B12 for three months B-12 supplementation is effective in alleviating hyperhomocysteinemia - 100  
    http://qualitycounts.com/fphomocysteine.html

26. Project: Genetic Causes Of Hyperhomocysteinemia (mHH) (www.onderzoekinformatie.n
    Project Genetic causes of hyperhomocysteinemia (mHH). Show printerfriendly view Print View switch to nl mutation. Titel, Genetische oorzaken van  
    http://www.onderzoekinformatie.nl/en/oi/nod/onderzoek/OND1270367/toon

27. Project: Molecular Genetic Basis Of Hyperhomocysteinemia. (www.onderzoekinformat
    Abstract, Part 1 Which mutations are causing mild hyperhomocysteinemia? Mild hyperhomocysteinemia is a risk factor for arterial as well as venous  
    http://www.onderzoekinformatie.nl/en/oi/nod/onderzoek/OND1271280/toon
    
    Extractions: Login English KNAW Research Information NOD - Dutch Research Database ... Research entire www.onderzoekinformatie.nl site fuzzy match Print View Titel Moleculair genetisch onderzoek van hyperhomocyste¯nemie. Abstract Part 1: Which mutations are causing mild hyperhomocysteinemia? Mild hyperhomocysteinemia is a risk factor for arterial as well as venous occlusions. Both genetic and acquired factors are known to influence the plasma homocysteine concentration. Different family studies reveal that the plasma homocysteine concentration is strongly influenced by genetic components. Until now we have discovered two mutations in the methylene tetrahydrofolate reductase gene which are genetic causes of mild hyperhomocysteinemia. The folate status is strongly influencing this phenotype/genotype relation (nature/nurture). These mutations can only explain a very small part of the genetic component of mild hyperhomocysteinemia. By use of different molecular genetic techniques genes involved in homocysteine metabolism will be investigated for homocysteine increasing mutations.

28. HUM-MOLGEN Events: 4th Conference On Hyperhomocysteinemia
    central resource for events in human genetics and molecular biology.  
    http://hum-molgen.org/meetings/meetings/2447.html

29. Clinical Trial: Randomized Study Of Folic Acid Therapy For Hyperhomocysteinemia
    Randomized Study of Folic Acid Therapy for hyperhomocysteinemia in Patients with End Stage hyperhomocysteinemia, Drug cyanocobalamin Drug folic acid  
    http://www.clinicaltrials.gov/ct/show/NCT00004495
    
    Extractions: Verified by FDA Office of Orphan Products Development August 1999 Sponsors and Collaborators: FDA Office of Orphan Products Development Georgetown University Information provided by: FDA Office of Orphan Products Development ClinicalTrials.gov Identifier: Purpose OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in hyperhomocysteinemia. II. Determine the requirement of co-supplementation with extra pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) daily in these patients. III. Assess the safety and tolerability of this therapy in these patients. Condition Intervention End Stage Renal Disease

30. Hyperhomocysteinemia
    hyperhomocysteinemia. Printable version. Etiology. methionine synthase deficiency by mutations of gene MTR (1p43). Mutations in the MTR gene result in the  
    http://www.humpath.com/article.php3?id_article=1714

31. PharmGKB: Hyperhomocysteinemia
    hyperhomocysteinemia Submitted by Alexander Steven Whitehead involving CBS, MTHFR, MTR, MTRR, NOS3, TYMS, and hyperhomocysteinemia.  
    http://www.pharmgkb.org/do/serve?objId=PA446892&objCls=Disease

32. NEJM -- Hyperhomocysteinemia As A Risk Factor For Deep-Vein Thrombosis
    Original Article from The New England Journal of Medicine hyperhomocysteinemia as a Risk Factor for DeepVein Thrombosis.  
    http://content.nejm.org/cgi/content/short/334/12/759
    
    Extractions: Add to Personal Archive ... PubMed Citation ABSTRACT Background Previous studies have suggested that hyperhomocysteinemia may be a risk factor for venous thrombosis. To assess the risk of venous thrombosis associated with hyperhomocysteinemia, we studied plasma homocysteine levels in patients with a first episode of deep-vein thrombosis and in normal control subjects. Methods We measured plasma homocysteine levels in 269 patients with a first, objectively diagnosed episode of deep-vein thrombosis and in 269 healthy controls matched to the patients according to age and sex. Hyperhomocysteinemia was defined as a plasma homocysteine level above the 95th percentile in the control Results Of the 269 patients, 28 (10 percent) had plasma homocysteine levels above the 95th percentile for the controls, as compared with 13 of the controls (matched odds ratio, 2.5; 95 percent

33. NEJM -- Hyperhomocysteinemia As A Risk Factor For Deep-Vein Thrombosis
    Correspondence from The New England Journal of Medicine hyperhomocysteinemia as a Risk Factor for DeepVein Thrombosis.  
    http://content.nejm.org/cgi/content/short/335/13/974
    
    Extractions: Add to Personal Archive Add to Citation Manager E-mail When Cited ... PubMed Citation To the Editor: The article by den Heijer et al. (March 21 issue) supports our finding that hyperhomocysteinemia is a risk factor for deep-vein thrombosis that is independent of coexisting abnormalities of naturally occurring anticoagulants. This important confirmation challenges the suggestion by Mandel et al., in their article in the same issue, that hyperhomocysteinemia increases the risk of thrombosis only if the elevation in homocysteinemia is associated with the presence of factor V Leiden. Unlike our study of patients with early-onset deep-vein thrombosis and their previous study of patients with recurrent deep-vein thrombosis

34. Hyperhomocysteinemia
    hyperhomocysteinemia Medical.WebEnds.com. hyperhomocysteinemia. hyperhomocysteinemias. An inborn error of methionone metabolism which produces an excess  
    http://medical.webends.com/kw/Hyperhomocysteinemia

35. Log In Problems
    What is the relationship between both elevated hyperhomocysteinemia and low vitamin B6 levels and the presence of nonvalvular AF?  
    http://www.medscape.com/viewarticle/490217

36. Alternative Medicine Review: Coronary Endothelial Function In Hyperhomocysteinem
    Coronary endothelial function in hyperhomocysteinemia improvement after BACKGROUND hyperhomocysteinemia is an independent risk factor for CAD.  
    http://www.findarticles.com/p/articles/mi_m0FDN/is_6_7/ai_96416626
    
    Extractions: AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Coronary endothelial function in hyperhomocysteinemia: improvement after treatment with folic acid and cobalamin in patients with coronary artery disease Alternative Medicine Review Dec, 2002 by FF Willems WR Aengevaeren GH Boers

37. Alternative Medicine Review: Hyperhomocysteinemia In Children Treated With Sodiu
    Full text of the article, hyperhomocysteinemia in children treated with sodium valproate and carbamazepine Abstract from Alternative Medicine Review,  
    http://www.findarticles.com/p/articles/mi_m0FDN/is_6_5/ai_68727276
    
    Extractions: AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine - Abstract Alternative Medicine Review Dec, 2000 by Verrotti A Pascarella R Trotta D

38. Role Of Hyperhomocysteinemia In Endothelial Dysfunction And Atherothrombotic Dis
    Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis.  
    http://www.nature.com/doifinder/10.1038/sj.cdd.4401451
    
    Extractions: NATURE.COM NEWS@NATURE.COM NATUREJOBS NATUREEVENTS ... Help SEARCH my account e-alerts subscribe register ... Site features NPG Subject areas Access material from all our publications in your subject area: Biotechnology Cancer Chemistry NEW! Dentistry Development Drug Discovery Earth Sciences ... Physics July 2004, Volume 11, Supplement 1, Pages S56-S64 Table of contents Previous Next Full text ... PDF Review Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease R C Austin , S R Lentz and G H Werstuck Department of Pathology and Molecular Medicine, McMaster University and the Henderson Research Centre, Hamilton, Ontario, Canada Veterans Affairs Medical Center and Department of Internal Medicine, University of Iowa, Iowa City, IA, USA Departments of Biochemistry and Medicine, McMaster University, Hamilton, Ontario, Canada Correspondence to: RC Austin, Henderson Research Centre, 711 Concession Street, Hamilton, Ontario, Canada L8V 1C3. Tel: +1 905 527 2299 ext. 42628; Fax: +1 905 575 2646; E-mail: raustin@thrombosis.hhscr.org Edited by G Melino Abstract Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular disease, including ischemic heart disease, stroke, and peripheral vascular disease. Mutations in the enzymes responsible for homocysteine metabolism, particularly cystathionine

39. Hyperhomocysteinemia - Chapter 3: Hypercoagulable States In Venous Disease
    Elevated homocysteine levels (hyperhomocysteinemia) have been found to increase the risk of venous thrombosis up to fourfold. According to one multicenter  
    http://www.venous-info.com/handbook/hbk03g.html
    
    Extractions: Homocysteine is an amino acid derived from methionine (an essential amino acid). Amino acids are the building blocks of proteins. Elevated homocysteine levels (hyperhomocysteinemia) have been found to increase the risk of venous thrombosis up to fourfold. According to one multicenter study, high blood levels of homocysteine are associated with early onset of vascular disease and venous thrombosis (10–25%) and with recurrence (19%) of deep venous thrombosis after 2 years. High homocysteine levels in people who have no symptoms can be normalized with supplements of folic acid, vitamin B , and vitamin B (although the benefit is not proved). Patients who have had deep venous thrombosis should have anticoagulation therapy with warfarin or low molecular weight heparin. The physician determines the duration of this treatment. Lifelong anticoagulation may be considered for patients with a high risk for recurrent deep venous thrombosis.

40. Hyperhomocysteinemia Presenting As Superior Mesenteric Artery Thrombosis Alexand
    Indian J Gastroenterol, The official publication of the Indian Society of Gastroenterology (ISG)  
    http://www.indianjgastro.com/article.asp?issn=0254-8860;year=2005;volume=24;issu

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