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Hepatolenticular Degeneration:     more detail

Studies of protein metabolism in hepatolenticular degeneration (Research report) by Frank L Iber, 1956 Diseases of the Nervous System described for Practitioners and Students with Chapters on the Neurological Complications of Liver Disease and Hepatolenticular Degeneration. by Francis Martin Rouse ; Walshe, John Michael Walshe, 1956-01-01 Wilson's Disease: A Clinician's Guide to Recognition, Diagnosis, and Management by George J. Brewer, 2001-05-31 Orphan Diseases and Orphan Drugs (Fulbright Papers, Proceedings of Colloquia, Vol 3) by I. Herbert Scheinberg, 1986-12 Wilson's Disease by Tjaard Hoogenraad, 1996-07-15 Wilson's Disease for the Patient and Family: A Patient's Guide to Wilson's Disease and Frequently Asked Questions about Copper by George J. Brewer M.D., 2002-04-09 Liver-brain relationships by Ian A Brown, 1957 Die Wilson'sche Krankheit (Westphal-Strümpell'sche Pseudosklerose): Eine Übersicht über die humangenetischen Forschungsergebnisse der Jahre 1967-1977 : Inaugural-Dissertation by Susanne Dworak, 1980 Wilson's disease: Familial presentatin by Ying-tung Kung, 1983

lists with details

1. Hepatolenticular Degeneration -- ECureMe.com
   UPDATED SARS INFORMATION,Check health symptoms, make a self diagnosis, ask a doctor or veterinarian online, view an encyclopedia of diseases treatments,  
   http://www.ecureme.com/emyhealth/data/Hepatolenticular_Degeneration.asp
   
   Extractions: DisplayAd("468","60"); eCureMe Life : Your Healthy Living. Click Here! Welcome, eCureMe.com Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health September 8, 2005 eCureMe Life Medical Supplies Calorie Count Physician Search ... Hospital Directory

2. Dr. Rose's Peripheral BrainWILSON'S DISEASE (HEPATOLENTICULAR
   WILSON'S DISEASE (hepatolenticular degeneration) I. Pathophysiology  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. AllRefer Health - Wilson's Disease (Hepatolenticular Degeneration)
   Wilson s Disease (hepatolenticular degeneration) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors,  
   http://health.allrefer.com/health/wilson-disease-info.html
   
   Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Copper Urine Test Wilson's disease is a rare inherited disorder. If both parents carry an abnormal gene for Wilson's disease, there is a 25% chance that each of their children will develop the disorder (i.e., it is an autosomal recessive disease). Wilson's disease causes the body to absorb and retain excessive amounts of copper. The copper deposits in the liver, brain, kidneys, and the eyes. The deposits of copper cause tissue damage, death of the tissues, and scarring, which causes the affected organs to stop functioning properly. Liver failure and damage to the central nervous system (brain, spinal cord) are the most predominant, and the most dangerous, effects of the disorder.

4. MedlinePlus Medical Encyclopedia Wilson's Disease
   Central nervous system. Copper urine test Alternative names Return to top. hepatolenticular degeneration Definition Return to top  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. AllRefer Health - Wilson's Disease Pictures & Images (Hepatolenticular Degenerat
   Wilson s Disease (hepatolenticular degeneration) pictures and images. Alternate Names hepatolenticular degeneration  
   http://health.allrefer.com/health/wilson-disease-pictures-images.html
   
   Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Copper Urine Test The copper urine test is performed by collecting urine at specific times for a 24-hour period. The urine is tested for the amount of copper present. The copper urine test is used to determine the presence of Wilson disease, a sometimes fatal condition in which the buildup of excess copper damages the liver, and eventually the kidneys, eyes and brain.

6. The Wilson's Disease Association International
   Learn about this disease, about the association, resources for consultation, diagnosis and treatment. Also copper content in various foods.  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. Hepatolenticular Degeneration - Cerebral Pseudosclerosis - Information Page With
   A rare autosomal recessive disease characterized by the deposition of copper in  
   http://www.hon.ch/HONselect/RareDiseases/EN/C06.552.413.html
   
   Extractions: Hepatolenticular Degeneration Definition: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN LIVER CORNEA ; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS TREMOR ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.

8. Healthopedia.com - Wilson's Disease (Hepatolenticular Degeneration)
   Wilson's Disease. Alternate Names hepatolenticular degeneration  
   http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. HONselect - Hepatolenticular Degeneration
   English, hepatolenticular degeneration, Cerebral Pseudosclerosis - Neurohepatic Degeneration - Pseudosclerosis - Wilson Disease  
   http://www.hon.ch/HONselect/RareDiseases/C06.552.413.html

10. HONselect - Hepatolenticular Degeneration
    Language MeSH term Accepted terms English hepatolenticular degeneration  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. Wilson's Disease (Hepatolenticular Degeneration)
    Wilson s Disease (hepatolenticular degeneration) is a genetic disorder that is fatal unless detected and treated before serious illness develops from copper  
    http://www.geocities.com/nutriflip/Diseases/WilsonsDisease.html
    
    Extractions: Go Back Wilson's Disease (Hepatolenticular Degeneration) Wilson's Disease (Hepatolenticular Degeneration) is a genetic disorder that is fatal unless detected and treated before serious illness develops from copper poisoning. Wilson's Disease affects one in thirty thousand people world wide. The genetic defect causes excessive copper accumulation. Small amounts of copper are essential as vitamins. Copper is present in most foods, and most people get much more than they need. Healthy people excrete copper they don't need, but Wilson's Disease patients cannot. The gene for Wilson's disease (ATP7B) was mapped to chromosome 13. The sequence of the gene was found to be similar to sections of the gene defective in Menkes disease, another disease caused by defects in copper transport. The liver of a person who has Wilson's disease does not release copper into bile as it should. Bile is a liquid produced by the liver that helps with digestion. As the intestines absorb copper from food, the copper builds up in the liver and injures liver tissue. Eventually, the damage causes the liver to release the copper directly into the bloodstream, which carries the copper throughout the body. The copper buildup leads to damage in the kidneys, brain, and eyes. If not treated, Wilson's disease can cause severe brain damage, liver failure, and death. Symptoms usually appear between the ages of 6 and 20 years, but can begin as late as age 40. The most characteristic sign is the Kayser-Fleischer ringa rusty brown ring around the cornea of the eye that can be seen only through an eye exam. Other signs depend on whether the damage occurs in the liver, blood, central nervous system, urinary system, or musculoskeletal system. Many signs would be detected only by a doctor, like swelling of the liver and spleen; fluid buildup in the lining of the abdomen; anemia; low platelet and white blood cell count in the blood; high levels of amino acids, protein, uric acid, and carbohydrates in urine; and softening of the bones. Some symptoms are more obvious, like jaundice, which appears as yellowing of the eyes and skin; vomiting blood; speech and language problems; tremors in the arms and hands; and rigid muscles.

12. Wilson('s) Disease (Hepatolenticular Degeneration)
    Wilson('s) Disease (hepatolenticular degeneration) Wilson's Disease Resources Information. Wilsons disease. Wilson disease. Wilson's Disease  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Hepatolenticular Degeneration
    Notes for physicians on Wilson Disease (hepatolenticular degeneration) covering diagnosis, clinical description, differential diagnosis, management,  
    http://omni.ac.uk/browse/mesh/D006527.html
    
    Extractions: low graphics other: Hemochromatosis GeneReviews : Wilson disease Notes for physicians on Wilson Disease (Hepatolenticular Degeneration) covering diagnosis, clinical description, differential diagnosis, management, molecular genetics and genetic counselling. Updated in April 2003, this resource forms part of GeneReviews (formerly GeneClinics profile), a peer-reviewed clinical genetic information resource that is funded by the US National Institutes of Health (NIH) and produced by the University of Washington, Seattle. This resource contains a summary and bibliographical references of the review. Hepatolenticular Degeneration / genetics

14. ? Wilson Disease
    Alternative Names hepatolenticular degeneration Causes, incidence, and risk factors  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Hepatolenticular Degeneration - Definition Of Hepatolenticular Degeneration By T
    Definition of hepatolenticular degeneration in the Online Dictionary. Meaning of hepatolenticular degeneration. What does hepatolenticular degeneration  
    http://www.thefreedictionary.com/hepatolenticular degeneration
    
    Extractions: Feedback Thesaurus Legend: Synonyms Related Words Antonyms Noun hepatolenticular degeneration - a rare inherited disorder of copper metabolism; copper accumulates in the liver and then in the red blood cells and brain Wilson's disease congenital disease genetic abnormality genetic defect ... inherited disorder - a disease or disorder that is inherited genetically

16. Wilsons Disease
    Med.Sci 532 StructureFunction Wilson Disease (hepatolenticular degeneration)  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Hepatolenticular Degeneration Topic - Unified Search Environment
    hepatolenticular degeneration Topic Tree hepatolenticular degeneration MSH/MH/D006527 DXP/SY/NOCODE LCH/PT/U002175 MTHICD9/ET/275.1  
    http://www.use.hcn.com.au/portals/shared/subject.`Hepatolenticular Degeneration`
    
    Extractions: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. Clinical features include LIVER CIRRHOSIS; LIVER FAILURE; SPLENOMEGALY; TREMOR; bradykinesia; DYSARTHRIA; CHOREA; MUSCLE RIGIDITY; Kayser-Fleischer rings (pigmented corneal lesions); ATAXIA; and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years. (From Adams et al., Principles of Neurology, 6th ed pp969-71) Synonyms and Source Vocabularies:

18. Penn State Faculty Research Expertise Database (FRED)
    Degeneration, hepatolenticular degeneration, Neurohepatic. Degeneration, Progressive Lenticular Degenerations, Hepatocerebral  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Wilson's Disease Hepatolenticular Degeneration - Patient UK
    Wilson s Disease is a genetic disorder in which copper builds up in the body, mainly in the liver and brain. Without treatment, the build up of copper  
    http://www.patient.co.uk/showdoc/23068935/
    
    Extractions: Hepatolenticular Degeneration Wilson's Disease is a genetic disorder in which copper builds up in the body, mainly in the liver and brain. Without treatment, the build up of copper causes serious illness, eventually causing death. Treatment is with medication to remove the excess copper and/or to prevent a further build up of copper. What is Wilson's disease? Wilson's disease is an condition where too much copper builds up in the body. It is a rare inherited disorder that affects about 1 in 30,000 people. It is named after Dr Samual Wilson who first described the disorder in 1912. If you inherit the genetic fault in Wilson’s disease, your body is not able to get rid of copper. Copper is a 'trace metal' which is in many foods. You need tiny amounts of copper to remain healthy. Normally, the body gets rid of any excess copper. People with Wilson's disease cannot get rid of excess copper and so it builds up in the body, mainly in the liver, the brain, the cornea and kidneys. Too much copper in the liver cells (the hepatocytes) is harmful and leads to liver damage. Damage to brain tissue mainly occurs in an area called the lenticular nucleus. Hence, Wilson's disease is also called 'Hepatolenticular Degeneration'. If left untreated, the damage becomes severe and eventually fatal. What causes Wilson's disease?

20. AllRefer Health - Wilson's Disease (Hepatolenticular Degeneration)
    Wilson's Disease (hepatolenticular degeneration) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk  
    http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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