Home  - Health_Conditions - Hemochromatosis

Books Baby Camera Phones Computers Games DVD Electronics Kitchen Magazines Music Garden Software Tools Toys Video Apparel & Accessories Jewelry & Watches Musical Instruments Health & Personal Care Beauty Sports & Outdoors Office Products

e99.com Bookstore

Images

Newsgroups

41-60 of 113    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Hemochromatosis:     more books (55)

Hemochromatosis Gene Variants in Three Different Ethnic Populations: Effects of Admixture for Screening Programs.: An article from: Human Biology by Alexandre C. Pereira, Gloria F. A. Mota, et all 2001-02-01 The Iron Disorders Institute Guide to Hemochromatosis A Genetic Disorder of Iron Metabolism - 2001 publication by WylieBurke, 2001 Test all PCT patients for hereditary hemochromatosis. (Porphyria Cutanea Tarda).: An article from: Skin & Allergy News 21st Century Complete Medical Guide to Hemochromatosis, Authoritative Government Documents, Clinical References, and Practical Information for Patients and Physicians by PM Medical Health News, 2004-04 Hemochromatosis: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Michelle, MS, CGC Bosworth, 2005 The Hemochromatosis Cookbook Recipes and Meals for Reducing the Absorption Of Iron in Your Diet - 2008 publication. by Chryl Garison, 2008 Arthritis: Gout, Rheumatoid arthritis, HFE hereditary hemochromatosis, Systemic lupus erythematosus, Juvenile idiopathic arthritis The Iron Disorders Institute Guide to Hemochromatosis. (Book Reviews). (book review): An article from: Southern Medical Journal by Ronald C. Hamdy, 2001-11-01 Hemochromatosis - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker, 2007-07-17 Iron Metabolism: Hfe Hereditary Hemochromatosis Hemochromatosis and chronic poisoning with copper, (Mellon lecture) by Frank Burr Mallory, 1926 Hemochromatosis (SuDoc HE 20.3302:H 37/6) by U.S. Dept of Health and Human Services, 2000 Rapid Cycle Real-Time PCR: Methods and Application by G. Burg, P. LeBoit, et all 2001-02-15 Rapid Cycle Real Time PCR - Methods and Applications: Microbiology and Food Analysis

lists with details

41. Iron Disorders Institute
    Nonprofit National Voluntary Health Agency that provides information about disorders of iron such as hemochromatosis.  
    http://www.irondisorders.org/

42. EMedicine - Hemochromatosis : Article By Sandor Joffe, MD
    hemochromatosis hemochromatosis is characterized by a progressive increase in total body iron stores with abnormal iron deposition in multiple organs.  
    http://www.emedicine.com/RADIO/topic323.htm
    
    Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Radiology Gastrointestinal Last Updated: March 11, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: hereditary hemochromatosis, primary hemochromatosis, secondary hemochromatosis, idiopathic hemochromatosis, hemosiderosis AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Differentials Cat Scan ... Bibliography Author: Sandor Joffe, MD , Section Chief of Abdominal Imaging, Department of Radiology, Beth Israel Medical Center Sandor Joffe, MD, is a member of the following medical societies: American College of Radiology American Roentgen Ray Society , and Radiological Society of North America Editor(s): Neela Lamki, MD , Professor, Department of Radiology, Baylor College of Medicine at Houston; Director, Gastrointestinal and Body Magnetic Resonance Imaging, Department of Radiology, Ben Taub General Hospital; Bernard D Coombs, MBChB, PhD

43. Iron Overload Disorder Support Forums Online: News
    Support group for those affected by hemochromatosis  
    http://www.iodforum.net
    
    Extractions: Hello, could you please tell me if ferritin level of 900 is high, I am currently having test for Haemochromatosis. I am also being treated for high blood pressure and gout. Are these related to Haemoch. could the gout be joint pain related to Haemoch. Im trying to learn as much as possible as family memebers have had serious liver problelms. Thanking you.

44. Hemochromatosis Education & Research
    UW hemochromatosis education and research site for patients and providers about HHC or iron overload disease including screening tests, genetics and  
    http://www.uwgi.org/hemochromatosis/flash/default.htm

45. Hemochromatosis
    Hereditary hemochromatosis, a condition in which excess (and ultimately toxic) levels of iron slowly accumulate in various organs, is one of the most common  
    http://healthlink.mcw.edu/article/974757337.html
    
    Extractions: Subscribe now >> Hemochromatosis is a condition in which the body accumulates excess amounts of iron. Serious and sometimes fatal health problems may result from the excess iron that accumulates in the body as a result of this genetic disorder. The excess iron slowly builds to toxic levels in tissues of major organs such as the liver, heart, brain, pancreas, lungs, and synovium (joints). These overburdened organs cease to function properly and eventually become diseased. Hereditary hemochromatosis (HHC) is one of the most common genetic diseases in humans, but it can be undiagnosed or misdiagnosed. Undiagnosed and untreated HHC can develop into diseases such as diabetes, heart trouble, arthritis, cirrhosis of the liver, neurological problems, depression, impotence, infertility, and liver cancer. Iron build up in those with HHC is slow, usually taking years to build to destructive levels. HHC/Iron overload generally manifests in a male's early thirties and is diagnosed in a male's mid to late fifties. For this reason HHC has acquired the mistaken identity of an older male's disease. HHC can be present in females, adolescents and possibly in children.

46. Iron Overload And Hemochromatosis
    Hereditary hemochromatosis is one of the most common genetic diseases in humans, but many people have never heard of it.  
    http://healthlink.mcw.edu/article/1025279068.html
    
    Extractions: Subscribe now >> Hereditary hemochromatosis is one of the most common genetic diseases in humans, but many people have never heard of it. In the United States, as many as one million people have evidence of the disorder, and up to one in every ten people may carry the gene for it. In people who have hemochromatosis, the body accumulates excess amounts of iron. This can result in serious and sometimes fatal health problems. Some diseases associated with hemochromatosis are arthritis, cirrhosis of the liver, diabetes, heart failure and liver cancer. Signs and Symptoms Early symptoms of hemochromatosis are nonspecific and might include fatigue, heart palpitations, joint pain, non-specific stomach pain, impotence and loss of menstrual periods. Even without other symptoms, people with hemochromatosis may have abnormal liver function test results. Symptoms – which reflect the tissue and organ damage that result from the disease – usually appear in middle age, although some people may develop problems earlier. Later disease symptoms include gray or bronze coloration to the skin, liver cirrhosis, liver cancer, diabetes, hypopituitarism, decreased pituitary or gonadal function, heart disease or heart failure, joint disease, chronic abdominal pain, severe fatigue and certain infections.

47. Hemochromatosis Diagnosis: Test To Diagnose - Iron Overload Diseases Assn.
    hemochromatosis diagnosis How to find out if you have hemochromatosis or other related iron overload disorders. Visit Iron Overload Diseases Assn. online  
    http://www.ironoverload.org/diagnosis.html

48. THE MERCK MANUAL, Sec. 11, Ch. 128, Iron Overload BR
    the term hemochromatosis has been applied (see Table 1281). hemochromatosis, an HLA-linked genetic Fe overload disorder, must be differentiated from  
    http://www.merck.com/mrkshared/mmanual/section11/chapter128/128a.jsp

49. Effects Of Hemochromatosis
    A brief overview of the causes and consequences of iron overload.  
    http://sickle.bwh.harvard.edu/hemochromatosis.html
    
    Extractions: revised February 4, 1999 Total body iron overload occurs most often due either to hereditary hemochromatosis or to repeated transfusions in patients with severe anemia. Hereditary hemochromatosis is the more common of the two by far. Hereditary haemochromatosis reflects a fractional increase in dietary iron absorption (Cox and Peters, 1978) (Cox and Peters, 1980) (Lynch et al., 1989). Tissue iron reaches dangerous levels after thirty or forty years. The gene responsible for hereditary haemochromatosis, HFE, resides on chromosome 6. Discovered in 1996, the gene encodes a protein that is homologous to the Class I HLA antigens (Feder, et al., 1996). The alteration in HFE protein that produces hereditary haemachromatosis involves the mutation of a cysteine to a leucine at position 282 (C282Y). People who have one copy of the mutant HFE gene are carriers who only rarely develop iron overload (usually in association with a second defect.) People with two copies of the mutant protein can develop iron overload and the myriad of problems that it can produce (see below). Nearly 90% of people who have hereditary haemochromatosis have the C282Y mutation in HFE (Nielson, et al., 1998). Only recently have investigators gained insight into the mechanism by which the mutation in HFE alters cellular iron metabolism. Iron in the circulation is bound to the protein, transferrin, which maintains it in a non-toxic state. Cells contain receptors for transferrin on their plasma membranes which mediate cellular iron uptake. Transferrin receptors bind iron-transferrin complexes which are taken into endosomes. Iron is separated from transferrin in the endosome, and is shuttled into the interior of the cell. The iron-free transferrin (apotransferrin) is recycled into the circulation and is free to bind and transport additional iron atoms. The HFE protein associates with the transferrin receptor and prevents internalization of iron-transferrin complex into cells (Gross, et al., 1998). The HFE protein, in effect, acts as a brake on cellular iron uptake.

50. Hospital Practice: Hemochromatosis
    hemochromatosis therefore presents the issues surrounding genetic testing in especially Like many other genetic diseases, hemochromatosis can be lethal,  
    http://www.hosppract.com/genetics/9908mmc.htm
    
    Extractions: With the discovery of the causative gene, the disorder stands revealed as America's single most common mendelian disease. Unlike other genetic diseases, it is already curable. Indeed, genetic screening makes it potentially preventable. Yet a finding of disease-related genotype can also lead to stigmatization. Hemochromatosis therefore presents the issues surrounding genetic testing in especially stark form. Dr. Press is Associate Professor of Pathology and Molecular and Medical Genetics and Director of Molecular Pathology, Oregon Health Sciences University School of Medicine, Portland. "I've been practicing for forty years and I've never seen a case of hemochromatosis." Such a statement represents a long- and widely held belief that hereditary hemochromatosis is a rare disorder, to be discussed chiefly as a medical curiosity. The belief is greatly mistaken. Hemochromatosis is common, affecting 0.3% to 0.8% of the American populationroughly one person in every 200, or about 1.5 million in all. Indeed, in America it is the single most common mendelian disease, far more common than cystic fibrosis, sickle-cell anemia, or phenylketonuria. Hence, any physician with lengthy experience will have seen tens or even hundreds of cases, which are all too likely to have gone unrecognized or attributed to other causes. Even among cirrhotic patients awaiting liver transplantation, a third of the cases arising from hemochromatosis have not been traced to that cause.

51. Hereditary Hemochromatosis To Begin The Lecture, Click The START
    Lists of Lectures Front Page. Hereditary hemochromatosis. To begin the lecture, click the START button above. Objective  
    http://www.pitt.edu/~super1/lecture/lec11811/
    
    Extractions: Lists of Lectures Front Page Hereditary Hemochromatosis To begin the lecture, click the START button above. Objective If you are the first time visitor, you might want to know [ How to navigate within and outside the lecture This is a beta version. Uploading date: September 27, 2003 Your comments to this version would be highly appreciated as well. Submit Your comments

52. Genome.gov | Learning About Hereditary Hemochromatosis
    Answers to frequently asked questions about hereditary hemochromatosis, published by the National Human Genome Research Institute.  
    http://www.genome.gov/10001214
    
    Extractions: triggerParms["cpp_5"] = "Referer:"+ cppUrlPatch (""); // Optional Home About NHGRI Newsroom Staff ... Specific Genetic Disorders Learning About Hereditary Hemochromatosis What do we know about hereditary hemochromatosis? Is there a test for hereditary hemochromatosis? NHGRI Clinical Research on Hereditary Hemochromatosis Additional Resources for Hereditary Hemochromatosis Information Hereditary hemochromatosis (HH) is a genetic disease that alters the body's ability to regulate iron absorption. If correctly diagnosed, HH is easily and effectively treated, but if untreated, it can lead to severe organ damage. Caucasians of northern European descent are at highest risk. An estimated one million people in the United States have hereditary hemochromatosis. HH causes the body to absorb too much iron. Normally humans extract needed iron from food via the intestines. When there is an adequate amount of iron, the body reduces its absorption to avoid excessive accumulations. In a person with HH, the mechanism for regulating iron absorption is faulty and the body absorbs too much iron. Over time - several years - this excess iron is deposited in the cells of the liver, heart, pancreas, joints and pituitary gland, leading to diseases such as cirrhosis of the liver, liver cancer, diabetes, heart disease and joint disease.

53. Genome.gov | Learning About Hereditary Hemochromatosis
    hemochromatosisDiagnosis of hemochromatosis. Ann Intern Med 1998;12992531; Barton JC, McDonnel SM, et al. Management of hemochromatosis. Ann Intern Med 1998;129932-9  
    http://www.genome.gov/page.cfm?pageID=10001214

54. Hereditary Hemochromatosis Disease Profile
    Images of all 24 human chromosomes and different genes that have been mapped to them. Free wall poster available from Web site.  
    http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/hh.shtml
    
    Extractions: Genetic Disorder Profile: Hemochromatosis For more about the gene that causes hereditary hemochromatosis, see the HFE Gene Profile . The following disease information was adapted from NIH Publication No. 00-4621 Hereditary Hemochromatosis Timeline - Hemochromatosis is first described by Tousseau, who cared for a diabetic patient with cirrhosis of the liver and bronzed skin pigmentation, classic symptoms of HH. - Von Recklinghausen names the disease "hemochromatosis" and identifies an iron-containing pigment in the liver cells of cirrhosis patients. - Sheldon describes the hereditary nature of the disease in his text Haemochromatosis - Stevens reported that a gene for HH may be located on chromosome 6 near the HLA-A locus. Simon concluded that HH demonstrates recessive inheritance. - Feder identifies the hemochromatosis gene and the missense mutations (Cys282Tyr and His63Asp) that cause HH. The hemochromatosis gene was originally HLA-H, but was later changed to HFE.

55. Hemochromatosis Gene
    Images of all 24 human chromosomes and different genes that have been mapped to them. Free wall poster available from Web site.  
    http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/hfe.shtml
    
    Extractions: Official Gene Symbol: HFE Alternate Symbol: HLA-H Name of Gene Product: hereditary hemochromatosis protein Locus: 6p21.3 The HFE gene is found in region 21.3 on the short (p) arm of human chromosome 6. Size: The HFE gene's 7 coding regions (exons) are scattered over about 10,000 base pairs of genomic DNA. Exons translated into the HFE protein are interspersed with segments of noncoding DNA (introns). After transcription, introns are spliced out and exons are pieced together to form an mRNA transcript about 2700 bp long. The mRNA is then translated into the 348-amino acid sequence of the hereditary hemochromatosis protein [1,2,3]. Mutations in the HFE gene can result in hereditary hemochromatosis (HH). Protein Function The HFE protein is a transmembrane protein expressed in intestinal and liver cells; it works in conjunction with another small protein called beta-2-microglobulin to regulate iron uptake [4]. Although homologous to other major histocompatibility complex (MHC) class I proteins that present antigens to killer T cells, the HFE protein appears to have no immunological function [5]. The HFE protein is an interesting example of how homology is not always an indicator of protein function.

56. Hemochromatosis
    A chapter from The Cleveland Clinic Disease Management Project written by Anthony S. Tavill, MD, which discusses hemochromatosis.  
    http://www.clevelandclinicmeded.com/diseasemanagement/gastro/hemochromatosis/hem
    
    Extractions: The Cleveland Clinic Foundation There are many inherited metabolic diseases that may have a pathologic impact on the liver. In many cases the liver component of these diseases is only an epiphenomenon of a more generalized systemic disorder. Examples of such epiphenomena are glycogen and lipid storage diseases in which hepatomegaly is a manifestation of the underlying metabolic defect although the liver is not necessarily the major target organ. However, there are three genetically determined diseases in which the liver may be the principal target organ, with manifestations of acute, subacute, or chronic disease that may become evident in early or later life. These are hereditary hemochromatosis (HH), a major disorder of iron overload; Wilson's disease , a genetic disorder of copper overload; and

57. Hemochromatosis - Page 1
    Hereditary hemochromatosis is a manic disorder in which individuals Hereditary hemochromatosis is thought to occur with equal frequency in both sexes.  
    http://www.gastromd.com/education/hemochromatosis.html
    
    Extractions: Print this page Hereditary hemochromatosis is a manic disorder in which individuals absorb slightly more iron than normal. This process occurs over decades. However, tissue damage occurs after significant amounts of iron have been absorbed. In most cases, the individual has absorbed approximately 15-20 grams of iron. It is at this amount of absorbed iron in which patients begin to have tissue damage. Also, it is at this amount of absorbed iron that produces significant organ system damage in individuals. Hereditary hemochromatosis is thought to occur with equal frequency in both sexes. However, since regular blood loss through normal menses occurs in females, the preponderance of cases is in males. This approximates 8-1 male to female ratio. Recently, a test has been developed which detects the cellular or genetic abnormalities responsible for many cases of hemochromatosis. The liver is the first site of iron overload in hereditary hemochromatosis. This is based on absorption of iron by the liver. When food is ingested, it is absorbed in the small intestine. This absorption passes into the veins that then form the portal vein. The portal vein then is directed to the liver. The portal vein then divides into small veins that provide the liver cells with nutrients absorbed from the intestine, thus, the liver is the first site in which iron absorption occurs. Typically, liver function tests are elevated in individuals.

58. What Is Hemochromatosis? - Liver Health Information - The American Liver Foundat
    hemochromatosis is an inherited condition that causes the body to absorb and store The hemochromatosis gene, called HFE, was identified in 1996 and is  
    http://www.liverfoundation.org/db/articles/1013
    
    Extractions: What is Hemochromatosis? Hemochromatosis is an inherited condition that causes the body to absorb and store too much iron. It is the most common inherited disorder affecting more than one million people in the United States who carry both copies of the abnormal gene. It is estimated that 10% of the population are carriers of one copy of the abnormal hemochromatosis gene. Many cases go undiagnosed because neither parents nor physicians have been alerted to the problem. The most vital factor in making an early diagnosis is enhanced recognition of the disease by doctors and patients. This is particularly important since early diagnosis and prompt treatment can prevent all of the long-term complications of the disease. The hemochromatosis gene, called HFE, was identified in 1996 and is inherited from both parents. It is most often diagnosed in people who exhibit symptoms and are between the ages of 40 and 60 years old. Women who lose iron through menstruation, pregnancy, and breast-feeding often develop symptoms at a later age than men. Anyone who has a blood relative with hemochromatosis should be tested even if there are no symptoms.

59. Hemochromatosis
    hemochromatosis is a hereditary disorder of small intestine in which the body If undiagnosed and left untreated, hemochromatosis can result in liver  
    http://www.brown.edu/Courses/Digital_Path/Liver/hemochromatosis.htm
    
    Extractions: Hemochromatosis General description H emochromatosis is a hereditary disorder of small intestine in which the body overabsorbs iron from food. Various organs such as pancreas, liver, and skin stores the excess iron. And these deposits eventually damages the organs and tissues. If undiagnosed and left untreated, hemochromatosis can result in liver disease, heart disease, and diabetes. Incidence Symptoms Pathophysiology Histopathology Brown, granular pigments seen here indicate the presence of iron in hepatocytes. Most of the hepatocytes appear pale due to autolysis.

60. Haemochromatosis - Wikipedia, The Free Encyclopedia
    From Wikipedia, the free encyclopedia. (Redirected from hemochromatosis). Haemochromatosis, also spelled hemochromatosis, is a hereditary disease  
    http://en.wikipedia.org/wiki/Hemochromatosis
    
    Extractions: Haemochromatosis , also spelled hemochromatosis , is a hereditary disease characterized by improper processing by the body of dietary iron which causes iron to accumulate in a number of body tissues, eventually causing organ dysfunction. It is the main iron overload disorder edit Haemochromatosis is notoriously protean, i.e. it presents with symptoms that are often initially attributed to other diseases. Symptoms may include: a darkish colour to the skin (see pigmentation , hence its name Diabete bronze when it was first described by Armand Trousseau in

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

41-60 of 113    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20