Patient 73 Test Answer extrapontine myelinolysis following rapid correction of iatrogenic hyponatremia . finding at autopsies of alcoholics with central pontine myelinolysis. http://www.bcm.edu/neurology/challeng/pat75/answer4a.html
Entrez PubMed A case of central pontine and extrapontine myelinolysis with early hypermetabolismon 18FDGPET scan. Roh JK, Nam H, Lee MC. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9
Entrez PubMed We report a patient with central pontine and extrapontine myelinolysis owing todisequilibrium syndrome. The patient had depressed consciousness, agitation, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
Portal Toolkit Invalid Site URL extrapontine myelinolysis after surgical removal of a pituitary tumour extrapontine myelinolysis is a rare and serious disorder characterized by patches http://ppv.ovid.com/pt/re/obes/fulltext.00000132-199809000-00013.htm
Portal Toolkit Invalid Site URL Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are caused by A case of central pontine and extrapontine myelinolysis with early http://ppv.ovid.com/pt/re/obes/fulltext.00000132-200112000-00010.htm
Extractions: Previous Case View Other Brain Degenerative/Demyelination Cases Next Case Xiang Liu, MD, PhD and PL Westesson, MD, PhD, DDS Clinical Presentation: A 54-year-old man, status-post liver transplant one month ago (end stage liver disease secondary to hepatitis C), presented with left facial droop, slurred speech, and had several falls. He was on Tacrolimus for immunosuppression. Radiological Findings: Axial CT images showed swelling in the central pons with low density, which caused the fourth ventricle compression ( Fig. 1 ). There were also several patchy lesions with low density in the periventricular and frontal subcortical areas ( Fig. 2
Extractions: Vol. 38 No. 4, April 1981 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Thompson DS Norenberg M Articles that cite this article Contact me when this article is cited D. S. Thompson, J. T. Hutton, J. C. Stears, J. H. Sung and M. Norenberg In two patients the diagnosis of central pontine myelinolysis (CPM), suspected on clinical grounds, was supported by computerized tomographic (CT) sections made perpendicular to the pons, and confirmed on postmortem examination. Extrapontine myelinolysis was suggested on CT scans in both cases, and confirmed in one. Computerized tomography may prove to be a
Extractions: Vol. 45 No. 1, January 1988 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Dickoff DJ Yahr MD Articles that cite this article Contact me when this article is cited D. J. Dickoff, M. Raps and M. D. Yahr Department of Neurology, Mount Sinai School of Medicine, City University of New York, New York. Several pathologic reports have indicated the occurrence of extrapontine sites of myelinosis associated with electrolyte disturbance and its rapid correction. Clinical evidence of the presence of such lesions, however
Journal Of Neuroimaging -- Sign In Page MR findings of central pontine and extrapontine myelinolysis. Satoh T.Serial MRI of extrapontine myelinolysis of the basal ganglia a case report. http://jon.sagepub.com/cgi/content/refs/15/1/85
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Journal Of Computer Assisted Tomography - UserLogin Karp BI, Laureno R. Pontine and extrapontine myelinolysis a neurologic disorderfollowing rapid correction of hyponatremia. Medicine 1993;7235973. http://www.jcat.org/pt/re/jcat/fulltext.00004728-199811000-00027.htm
CMJ_netprints Pontine and extrapontine myelinolysis caused by hyponatremia Report of two cases.LUO Benyan?,ZHANG Minming?, RUAN Lingxiang?, http://www.cmj.org/netprints/02/06/020611.htm
Singapore Medical Journal The latter condition is termed extrapontine myelinolysis (EPM)(1). In both CPMand EPM, bilateral and symmetrical involvement is usually the rule (Figs 2a http://www.sma.org.sg/smj/4101/articles/4101me1ans.htm
Extractions: C Y Chan, H S Lam, J R Jinkins IMAGE INTERPRETATION MR scans showede a 1 cm area of T2 hyperintensity in the central pontine region (Fig 1a) . In a patient with a history of sodium replacement, this finding is in keeping with osmotic myelinolysis (or central pontine myelinolysis). Multiple areas of T2 hyperintensity were seen in the basal ganglia and deep white matter (Fig 1b) , representing part of the same process. DIAGNOSIS Osmotic myelinolysis (central pontine myelinolysis) CLINICAL COURSE The patient did not improve clinically over the following months. She developed spastic tetraparesis, pseudobulbar palsy and horizontal nystagmus. Because of mutism, antidepressants were tried but they were not effective. She remained bed-ridden and ventilator-dependent. During her hospital stay, she developed several episodes of chest and urinary tract infection which were controlled with antibiotics. The patient finally died one year later due to multiple organ failure and sepsis. DISCUSSION Osmotic myelinolysis (OM) is a demyelinating disease that can develop following rapid correction of hyponatremia from any cause. It was originally described in chronic alcoholics. Other reported associations include malnourished status, renal failure, diabetes mellitus, and post-orthotopic liver transplantation
REFERENCES Karp BI, Laureno R. Pontine and extrapontine myelinolysis a neurologic disorder A case of central pontine and extrapontine myelinolysis with early http://www.sma.org.sg/smj/4101/references/4101me1ref.htm
Extractions: REFERENCES Ho VB, Fitz CR, Yoder CC, Geyer CA. Resolving MR features in osmotic myelinolysis (central pontine and extrapontine myelinolysis). AJNR 1993; 14:163-7. Martin PJ, Young CA. Central pontine myelinolysis: clinical and MRI correlates. Postgrad Med J 1995; 71:430-42. Laaureno R, Karp BI. Myelinolysis after correction of hyponatremia. Ann Intern Med 1997; 126:57-62. McGraw P, Edwards-Brown MK. Reversal of MR findings of central pontine myelinolysis. J Comput Assist Tomogr 1998; 22:989-91. Gregorio L, Sutton CL, Lee DA. Central pontine myelinolysis in a previously healthy 4-year-old child with acute rotavirus gastroenteritis. Pediatrics 1997; 99:738-43. Karp BI, Laureno R. Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia. Medicine (Baltimore) 1993; 72:359-73. Korogi Y, Takahashi M, Shinzato J, Sakamoto Y, Mitsuzaki K, Hirai T, et al. MR findings in two presumed cases of mild central pontine myelinolysis. AJNR 1993; 14:651-4. Gocht A, Colmant HJ. Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 1987; 6:262-70.
JPMA ::: Central and extrapontine myelinolysis in a patient in spite of a careful correctionof hyponatremia. Clin Nephrol 2001;5524853. http://jpma.org.pk/jpma/6june05/fulltex11.htm
Extractions: Introduction Focal symmetric demyelination in the CNS may be precipitated by aggressive correction of a hyper or hypoosmolar state - osmotic myelinolysis.1 Since the first descriptions of central pontine myelinolysis (CPM) were put forth in 1959 in alcoholic patients, it has become evident that myelinolysis is not exclusively restricted to the pons. In many cases myelinolysis may share other brain regions, while in still others the pons may not be affected at all - extra-pontine myelinolysis(EPM).2 Hence, specific anatomical locations are more susceptible to demyelination than others.
Extractions: This Article Extract Full Text (PDF) P ... Citation Map Services E-mail this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Gregorio, L. Articles by Lee, D. A. Related Collections References Acute gastroenteritis is one of the most common childhood illnesses encountered today. Vomiting and diarrhea often cause dehydration. Although the disease is usually self-limiting, patients may require rehydration therapy. Central pontine myelinolysis (CPM) is rare, with fewer than 30 cases reported in children. First described in 1959, it is a demyelinating process that affects the central pons and may involve other white matter areas. CPM presents with an altered
Myelinolysis, Central Pontine Central Pontine Myelinolysis; extrapontine myelinolysis; Extrapontine Myelinoclasis;Myelinoclasis, Central Pontine; Pontine Myelinolysis, Central; http://medical.webends.com/kw/Myelinolysis, Central Pontine
Extractions: WWW Medical.WebEnds.com Central Pontine Myelinolysis; Extrapontine Myelinolysis; Extrapontine Myelinoclasis; Myelinoclasis, Central Pontine; Pontine Myelinolysis, Central; Central Pontine Myelinoclasis; Extrapontine Myelinoclases; Extrapontine Myelinolyses A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA DYSARTHRIA ; DYSPHAGIA; and alterations of consciousness . Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons . This condition is usually associated with systemic disorders such as HYPONATREMIA ; chronic ALCOHOLISM LIVER FAILURE ; severe BURNS ; malignant NEOPLASMS ; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS . The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology , 6th ed, pp1125-6)
Neurology -- Sign In Page Pontine/extrapontine myelinolysis occurring in the setting of an eating disorder.C. Singer, MD , D. Lorenzo, MD , S. Papapetropoulos, MD, PhD , A. Mesa, http://www.neurology.org/cgi/content/full/64/12/2156
Extractions: Submit a response ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Singer, C. Articles by Bowen, B. Related Collections MRI