Extractions: POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects. Common symptoms include progressive weakness of the nerves in the arms and legs, an abnormally enlarged liver and/or spleen (hepatosplenomegaly), abnormally darkening of the skin (hyperpigmentation) and excessive hair growth (hypertrichosis). Endocrine abnormalities such as failure of the ovaries and testes (gonads) to function properly (primary gonadal failure) and diabetes mellitus type I may be present. Specific endocrine abnormalities associated with POEMS syndrome vary from case to case.
Webkatalog 1. Mayo Clinic Rochester Information about POEMS syndrome, what it is, symptoms, diagnosis, treatment and who gets it. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Crow-Fukase Syndrome - General Practice Notebook crowfukase syndrome. POEMS is an acronym for. polyneuropathy. slow onset ofmixed motor and sensory polyneuropathy; peripheral nerve demyelination with http://www.gpnotebook.co.uk/cache/-1046872034.htm
Extractions: Submit a response Alert me when this article is cited Alert me when Correspondence are posted ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Nakanishi, T. Articles by Ozaki, Y. T Nakanishi, I Sobue, Y Toyokura, H Nishitani, Y Kuroiwa, E Satoyoshi, T Tsubaki, A Igata and Y Ozaki Clinical manifestations of 102 cases with the Crow- Fukase syndrome (the syndrome of polyneuropathy, anasarca, skin changes, endocrinopathy, dysglobulinemia, and organomegaly), with or without myeloma, were reviewed. Fifty-six cases with myeloma consisted of 31 with osteosclerotic, 17 with mixed osteosclerotic and osteolytic, and 8 with osteolytic. Forty-six cases without myeloma consisted of 2 with extramedullary plasmacytoma, 33 with M
Neurology -- Table Of Contents (June 1 1984, 34, [6]) I Sobue, Y Toyokura, H Nishitani, Y Kuroiwa, E Satoyoshi, T Tsubaki, A Igata,and Y Ozaki The crowfukase syndrome a study of 102 cases in Japan http://www.neurology.org/content/vol34/issue6/
Extractions: [Search ALL Issues] To see an article , click its [Full Text] link. To review many abstracts , check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time , click its [Abstract] link. RP Lesser, CE Pippenger, H Luders, and DS Dinner High-dose monotherapy in treatment of intractable seizures
POEMS Syndrome Treatment Options At Mayo Clinic Treatment of POEMS Syndrome at Mayo Clinic (Synonyms crowfukase syndrome, PEP syndrome, Shimpo syndrome and Takatsuki syndrome) http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Entrez PubMed crowfukase syndrome is a disease of plasma cell dyscrasia. The diagnosiswas crow-fukase syndrome based on these clinical features. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
POEMS Syndrome Synonyms. crowfukase syndrome. PEP Syndrome. Polyneuropathy-organomegaly-endocrinopa. .. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Entrez PubMed A 51year-old woman was diagnosed as crow-fukase syndrome on July 1997, presentingwith lymph node s http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
EMedicine - POEMS Syndrome Article By Wingfield Rehmus, MD, MPH POEMS syndrome first was described by Crow in 1956 and then by Fukase in 1968. The syndrome was termed crowfukase syndrome (by which it is http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Internet Scientific Publications, LLC. crowfukase syndrome is a rare multisystem disorder characterized by The apparent source of VEGF overproduction in crow-fukase syndrome has not yet been http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijeicm/vol7n2/crow.xml
EMedicine - POEMS Syndrome Article Excerpt By Wingfield Rehmus POEMS syndrome first was described by Crow in 1956 and then by Fukase in 1968. The syndrome was termed crowfukase syndrome (by which it is http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Internal Medicine Last Updated: July 10, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: Crow-Fukase syndrome, Takatsuki syndrome, PEP, polyneuropathy endocrinopathy plasma cell dyscrasia, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Wingfield Rehmus, MD, MPH , Co-Director of Clinical Trials, Clinical Instructor, Department of Dermatology, Stanford University Medical Center Coauthor(s): Alexa Boer Kimball, MD, MPH , Director of Clinical Trials, Department of Dermatology, Brigham and Women's Hospital, Harvard University School of Medicine Wingfield Rehmus, MD, MPH, is a member of the following medical societies: American Academy of Dermatology Editor(s): Neil Shear, MD
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: Crow-Fukase syndrome, Takatsuki syndrome, PEP, polyneuropathy endocrinopathy plasma cell dyscrasia, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes Background: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare multisystemic disease that occurs in the setting of a plasma cell dyscrasia. The pathophysiologic link between the constellation of symptoms and the underlying disease is not well understood, but the link may be related to changes in the levels of a cytokine or a growth factor. POEMS syndrome first was described by Crow in 1956 and then by Fukase in 1968. The syndrome was termed Crow-Fukase syndrome (by which it is known in Japan) by Nakanishi in a study of 102 cases in Japan. In 1980, the acronym POEMS was coined by Bardwick et al based on the 5 main features of the disease, namely, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. No specific case definition for POEMS exists; however, most authors agree that patients with POEMS syndrome should have 3 or more of the 5 features. The pathophysiology of the disease is not known; however, elevated levels of cytokines and growth factors have been implicated. The polyneuropathy associated with POEMS syndrome is a bilateral symmetric disturbance. It involves both motor and sensory nerves, begins distally, and has a progressive proximal spread. Associated cranial or autonomic nerves are not involved. Both demyelination and axonal degeneration are noted.
