Cleidocranial Dysplasia (CCD, CLCD) A list of synonyms, summary and major features. http://www.nlm.nih.gov/mesh/jablonski/syndromes/syndrome233.html
Extractions: Syndrome cleidocranial dysplasia (CCD, CLCD) Synonyms Marie-Sainton syndrome Scheuthauer-Marie-Sainton syndrome cleidocranial digital dysostosis cleidocranial dysostosis craniocleidodysostosis dysostosis cleidocranialis dysostosis cleidocraniodigitalis dysostosis cleidocraniopelvina dysostosis generalisata dysplasia cleidocranialis dysplasia cleidofacialis mutational dysostosis osteodental dysplasia (ODD) pelvicocleidocranial dysostosis Summary A congenital disorder of bone formation with clavicular hypoplasia or agenesis with a narrow thorax, allowing approximation the shoulders in front of the chest occurring with delayed ossification of the skull, excessively large fontanelles, and delayed closing of the sutures. The fontanelles may remain open until adulthood, but the sutures often close with interposition of wormian bones. Bosses of the frontal, parietal, and occipital regions give the skull a large globular shape with small face. The characteristic skull abnormalities are sometimes referred to as the "Arnold head" named after the descendants of a Chinese who settled in South Africa and changed his name to Arnold. More than 100 additional anomalies may be associated, including wide pubic symphysis, dental abnormalities, short middle phalanges of the fifth fingers, delayed skeletal maturation, hearing deficiency, and mild mental retardation in some cases. Major Features Head and neck: Brachycephaly with bossing of the frontal, parietal, and occipital bossing give the head a large globular appearance with a small face because of smallness of the maxillary and zygomatic bones and relative prognathism. Additional abnormalities include open fontanels; open cranial sutures; calvarial thickening in the supraorbital part of the bone, squama of the temporal bones, and the occipital bone; wormian bones filling suture lines, occasional absence of the parietal bones, faulty development of the foramen magnum, and dysplasia of the paranasal sinuses and mastoids.
Cleidocranial Dysplasia Of all the cases of cleidocranial dysplasia, onethird are spontaneous and two-thirds New advances in procedures to treat cleidocranial dysplasia are http://www.faces-cranio.org/Disord/CCD.htm
Extractions: Cleidocranial Dysplasia ( cleido = collar bone, + cranial = head, + dysplasia = abnormal forming) , also known as Cleidocranial Dysostosis and Marie-Sainton Disease, is a condition characterized by defective development of the cranial bones and by the complete or partial absence of the collar bones (clavicles). Characteristics include: Delayed closure (ossification) of the space between the bones of the skull (fontanels) Premature closing of the coronal suture Protruding jaw (mandible) and protruding brow bone (frontal bossing) Wide nasal bridge due to increased space between the eyes (hypertelorism) High arched palate or possible cleft palate Short stature Scoliosis of the spine There is no link between anything the mother did or did not do while she was pregnant and the occurrence of Cleidocranial Dysplasia. It is transmitted as an autosomal dominant trait. The cause is not yet known, but several chromosome abnormalities have been linked with this syndrome, including chromosome 6p21.
Cleidocranial Dysplasia (CCD, CLCD) View the Full Record. Syndrome cleidocranial dysplasia (CCD, CLCD) Synonyms. MarieSainton syndrome. Scheuthauer-Marie-Sainton syndrome http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Cleidocranial Dysplasia cleidocranial dysplasia is a rare skeletal dysplasia characterized by short stature, distinctive facial features and narrow, sloping shoulders caused http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Cleidocran Open Directory Health Conditions and Diseases Rare Disorders National Library of Medicine cleidocranial dysplasia (CCD, A Natural Historyof cleidocranial dysplasia - An article from Baylor College of Medicine. http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Cleidocranial Dysplasia
Osteogenesis Through CBFA-1; Cleidocranial Dysplasia cbfa1 (+)/cbfa1 () mice showed skeletal defects similar to those of a human syndrome, cleidocranial dysplasia (CCD). In this syndrome http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Extractions: Printer-Friendly Format FREE Newsletters Email to a Friend ... Next What is cleidocranial dysplasia? Cleidocranial dysplasia (CCD) is a genetic (inherited) disorder of bone development which is characterized by: Absent or incompletely formed collar bones (the "cleido-" part refers to the clavicles, the collar bones). A person with this condition can bring his/her shoulders together or nearly so; and Typical cranial and facial abnormalities with square skull, late closure of the sutures of the skull, late closure of the fontanels (the soft spots), low nasal bridge, delayed eruption of the teeth, abnormal permanent teeth, etc. How does a person acquire CCD? The disorder is transmitted genetically in an autosomal dominant manner. This means that one parent with the condition has a 50:50 chance of passing CCD to each of their children. Boys and girls are equally affected. What is the molecular genetic basis for CCD?
Cleidocranial Dysplasia cleidocranial dysplasia is a rare skeletal dysplasia characterized by shortstature, distinctive facial http://my.webmd.com/hw/raising_a_family/nord961.asp
Extractions: Cleidocranial dysplasia is a rare skeletal dysplasia characterized by short stature, distinctive facial features and narrow, sloping shoulders caused by defective or absent collarbones (clavicles). Major symptoms may include premature closing of the soft spot on the head (coronal), delayed closure of the space between the bones of the skull (fontanels), narrow and abnormally shaped pelvic and pubic bones and deformations in the chest (thoracic region). Delayed eruption of teeth, moderately short stature, a high arched palate, a wide pelvic joint, failure of the lower jaw joints to unite, and fingers that are irregular in length may also be present. Cleidocranial dysplasia is inherited as an autosomal dominant genetic trait.
Cleidocranial Dysplasia - Medical Dictionary Definitions Of 1 cleidocranial dysplasia Index Next page cleidocranial dysplasia A genetic (inherited) disorder of bone development characterized by http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
CLEIDOCRANIAL DYSPLASIA Patient medical question and answer from The Child Behavioral Health Forum.Health topic area and articles about normal child development Topics ,. http://www.medhelp.org/forums/ChildBehavior/messages/32058.html
Extractions: chattymom This inherited disorder affects the development of bones and can include an absent or not completely formed collar bone, dental abnormalities and facial appearance often typified by protruding jaw, wide nasal bridge, and poorly aligned teeth. The disorder requires that only one parent has the trait, and the risk of recurrence is 50%. If your friend conducts an internet search, she will find a number of web sites devoted to the condition. [Thread closed to new comments] Child Behaviorial Health Forum Child Behaviorial Health Archives Med Help International
Cleidocranial Dysostosis a CHORUS notecard document about cleidocranial dysostosis http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
