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Beryllium Disease: more detail

Chronic beryllium disease and sensitization at a beryllium processing facility.(Research/ Environmental Medicine): An article from: Environmental Health Perspectives by Kenneth Rosenman, Vicki Hertzberg, et all 2005-10-01

Report on the beryllium problem: As discussed at the sixth Saranac Symposium, Saranac Lake, N.Y., 27 September to 3 October, 1947 by W. E Park, 1947

Beryllium toxicity (Case studies in environmental medicine) by Dennis M Green, 1997

lists with details

Beryllium Symposium
Immunopathology of BerylliumInduced Granulomatous Disease Chronic beryllium disease (CBD) is a lung disease similar clinically to other granulomatous
http://www.ornl.gov/sci/techresources/meetings/beryllium/session1.shtml

Extractions: The National Jewish Medical and Research Center Session 1. Immunopathology of Beryllium-Induced Granulomatous Disease Characterization of Beryllium-Specific Memory CD4+ T Cells in Patients with Chronic Beryllium Disease Andrew P. Fontenot , Scott J. Canavera, Laia Gharavi, Lee S. Newman, and Brian L. Kotzin andrew.fontenot@uchsc.edu Evidence suggest that CD4+ T cells play a critical role in the development of chronic beryllium disease (CBD). Using intracellular cytokine staining, we found that the frequency of beryllium-specific CD4+ T cells in the lungs of 10 CBD patients ranged from 1.4-29% (mean 18.8%), and these T cells expressed a Th1-type phenotype in response to beryllium sulfate (BeSO ). Few, if any, beryllium-specific CD8+ T cells were identified. In contrast, the frequency of beryllium-responsive CD4+ T cells in the blood of these subjects ranged from undetectable to 1 in 500. No correlation was observed between the frequency of beryllium-responsive BAL CD4+ T cells detected with intracellular cytokine staining and lymphocyte proliferation in culture after BeSO
Toxics Law Reporter - Plant Worker With Beryllium-Related Disease
Beryllium Plant Worker With BerylliumRelated Disease beryllium and chronic beryllium disease and asked him to participate in a beryllium worker study
http://subscript.bna.com/SAMPLES/txlr.nsf/0/a7d062531b33b82c85256fd4007800a8?Ope
Beryllium Central Jon Gelman Attorney 1-888-696-7900
beryllium disease benefits for energy workers and their families, bystanders and household contact. Medical and legal resources.
http://www.berylliumcentral.com/
Policy Analysis And Clinical Research On Occupational Beryllium Exposure At DOE
Investigating Chronic beryllium disease prevalence among former Chronic beryllium disease (CBD) involves the ongoing stimulation of the immune system
http://www.cresp.org/dcwrkshp/posters/be/be.html

Extractions: This research supported in part by CRESP through the Department of Energy Cooperative Agreement #DE-FC01-95EW55084. This support does not constitute endorsement of views expressed. The US Department of Energy has used beryllium in nuclear materials production, reactor rod fabrication, nuclear vessel cladding and many other uses since the 1940s. The industrial use of beryllium was found to result in an acute respiratory disease, acute beryllium disease, leading the Atomic Energy Commission to establish an airborne concentration standard of 2 µg/m3 for the workplace based on then accepted standards for other metals. Adoption of this standard has effectively eliminated the presence of acute beryllium disease. However, epidemiologic studies carried out during the 1980-90s has revealed the presence of another form of lung disease, chronic beryllium disease (CBD), among workers at US DOE sites. In 1997, the Consortium for Risk Evaluation with Stakeholder Participation (CRESP) began a series of research efforts to investigate the prevalence of CBD among former beryllium workers at Hanford, evaluation of alternatives to the current screening tools for identifying pre-clinical disease, and policy implications of alternative occupational health program designs to reduce disease incidence among future beryllium workers, such as those involved in decontamination and decommissioning former beryllium facilities.
Log In Problems
Beryllium Sensitization May Progress to Chronic beryllium disease CME. News Author Laurie Barclay, MD CME Author Désirée Lie, MD, MSEd Disclosures
http://www.medscape.com/viewarticle/497063
Chronic Beryllium Disease Prevention Program-Provides Information And Resources
This web site locates thousands of US Government science and technology resources on the web that let you tap into government expertise, services,
http://www.scitechresources.gov/Results/show_result.php?rec=1280
Major Histocompatibility Locus Genetic Markers Of Beryllium Sensitization And Di
HLADPB1 and Chronic beryllium disease A HuGE Review Am. J. Epidemiol., March 1, 2003; 157(5) 388 - 398. Abstract Full Text PDF
http://erj.ersjournals.com/cgi/content/abstract/18/4/677

Extractions: This Article Full Text Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed ... Cited by other online articles Search for citing articles in: ERS Journals Ltd Major histocompatibility locus genetic markers of beryllium sensitization and disease C. Saltini L. Richeldi M. Losi M. Amicosante C. Voorter E. van den Berg-Loonen R.A. Dweik H.P. Wiedemann D.C. Deubner and C. Tinelli Division of Respiratory Diseases of the University of Rome "Tor Vergata" at the National Institute for Infectious Diseases (INMI), Spallanzani Hospital, Rome, Italy. Division of Pneumology, Policlinico, Modena, Italy. Laboratory of Clinical Pathology, INMI, Spallanzani Hospital, and the Dept of Cell Biology, University of "Tor Vergata", Rome, Italy.
Berylliosis
(beryllium disease). by Rick Alan. Definition. Berylliosis is an occupational lung disease. It occurs in people who work with beryllium.
http://healthgate.partners.org/browsing/browseContent.asp?fileName=22480.xml&tit
Chronic Beryllium Disease - Information & News
Researchers at National Jewish Medical and Research Center have developed a method for finding the molecular targets of the immune system,
http://www.news-medical.net/?keyword=Chronic beryllium disease
Medical News: Beryllium Disease May Not Become Evident For 40 Years - WrongDiagn
Medical news summary describing beryllium disease may not become evident for 40 years in relation to symptoms, diagnosis, misdiagnosis and treatment.
http://www.wrongdiagnosis.com/news/beryllium_disease_may_not_become_evident_for_

Extractions: Medical News Summary (summary of medical news story as reported by Bradenton): Concerns are rising about the number of people potentially affected by beryllium disease. At the time, there were no safety standards for working in a beryllium plant and many people may have been directly or indirectly exposed to it. Even wives washing uniforms may have come into contact. Beryllium is a carcinogen. Symptoms of beryllium poisoning may not become evident for 40 years, beryllium sensitivity and chronic beryllium disease include shortness of breath, sudden weight loss, tiredness, skin problems and night sweats. Treatment can be effective if the disease is diagnosed early enough.
Chronic Beryllium Disease (berylliosis)
berylliosis â Cleveland Clinic Pulmonary, Allergy Critical Care â leaders in the diagnosis and treatment of pulmonary, respiratory and allergic
http://cms.clevelandclinic.org/ccfpulmonary/body.cfm?id=51
Rates Of Beryllium Disease On The Rise
beryllium disease slowly destroys the lungs after the dust is inhaled. Risks of beryllium disease related to work processes at a metal alloy and oxide
http://www.biomed.lib.umn.edu/hmed/1999/03/19990329_ber.html

Extractions: View abstracts from: Search all years Health and Medicine in the News Beryllium dangers were kept secret A recent investigation into the safety practices at a beryllium plant in Ohio has found that federal officials knew of the risks to workers but did little rectify the situation. Beryllium disease slowly destroys the lungs after the dust is inhaled. Toledo Blade. Beryllium dangers were kept secret. Star Tribune, 1999 March 29: A4(col. 1-4). Kreiss K., et al. Risks of beryllium disease related to work processes at a metal alloy and oxide production plant. Occupational and Environmental Medicine 1997 Aug; 54. lam /03/30/1999 MNCAT BioMedSearch MEDLINE Library Instruction ... BIS Bio-Medical Library
Seminar At WVU To Focus On Chronic Beryllium Disease
Exposure to beryllium in the workplace may lead to various diseases including However? even a family member can develop chronic beryllium disease from
http://www.nis.wvu.edu/2002_Releases/BeryilliumDisease.htm

Extractions: News Release Back to Newsroom Friday August 30, 2002 Seminar at WVU to focus on Chronic Beryllium Disease CONTACT: Ainsley Weston , NIOSH CDC, 304-285-6221 A toxicologist from the National Institute for Occupational Safety and Health (NIOSH) Centers for Disease Control and Prevention will speak on "Genetic Factors in Chronic Beryllium Disease" at 3:30 p.m. Tuesday, Sept. 3, in Room 2001 of the Agricultural Sciences Building, Evansdale Campus. Ainsely Weston will give the next presentation in a seminar series organized by West Virginia Universitys interdisciplinary program in Genetics and Developmental Biology. A strong, lightweight, alkaline earth element with a high melting point, beryllium has been used most successfully in components of nuclear reactors nuclear weapons, aircraft and spacecraft. Beryllium compounds are used in ceramics for electronics, in dental bridges and in some sports equipment. Exposure to beryllium in the workplace may lead to various diseases including chronic beryllium disease, which causes a painful scarring of the lung tissue. Workers in certain occupations and industries are most likely to develop the disease. However even a family member can develop chronic beryllium disease from exposure to dust on the workers clothing hair or body.
Chronic Beryllium Disease Dust Exposure Attorneys Berkeley California Law Firm
The California lawyers at Paul, Hanley Harley represent victims and families in Beryllium and other beryllium related cases throughout the country.
http://www.phhlaw.com/PracticeAreas/PracticeAreaDescriptions19.asp

Extractions: Chronic Beryllium Disease is an incurable lung disease caused by the inhalation of beryllium dust and fumes. Some of the symptoms of Chronic Beryllium Disease are cough, shortness of breath, fatigue, weight loss, loss of appetite, fever, and night sweats. The use of steroids is the primary way to control the progression of this disease. Supplemental oxygen may be needed for some individuals. A lung transplant may be the last alternative for some. There is a special test, that can be done to see if you are sensitized to beryllium. This test is called a beryllium lymphocyte proliferation transformation test. It is typically a blood test, but it can also be done through a lung washing. X-rays may be helpful to see if there is any scarring of the lungs caused by the inhalation of beryllium dust or fumes. A special type of scarring of the lungs called granuloma may be found in lung biopsy tissue. Pulmonary function tests can show if there are abnormalities in the breathing functions of the lungs. Sometimes beryllium disease is misdiagnosed as sarcoidosis, but a lymphocyte transformation test and a history of exposure to beryllium can differentiate these diseases.
Community Meeting On Beryllium Disease -- Ohio Citizen Action
Community meeting on beryllium disease, with Dr. Kathleen Fagan, occupational health specialist and expert on beryllium and toxic exposures
http://www.ohiocitizen.org/campaigns/brush/genoa_mtg.html

Extractions: Dr. Kathleen Fagan will join us to discuss the dangers of living near a beryllium plant and beryllium disease. Dr. Fagan is a occupational medicine specialist, trained in work related toxic exposures and recognized by National Institute of Occupational Safety and Health as a beryllium expert. This meeting is open to the public. When:
Resources For Dental Professionals -- Ohio Citizen Action
You dont have to be a beryllium worker to get beryllium disease. Anybody exposed to beryllium dust or fumes can get it. Some contract workers at beryllium
http://www.ohiocitizen.org/campaigns/brush/dentalresource.html

Extractions: You dont have to be a beryllium worker to get beryllium disease. Anybody exposed to beryllium dust or fumes can get it. Some contract workers at beryllium plants, automotive manufacture workers and dental lab technicians have developed beryllium disease. All dental professionals exposed to beryllium dust or fumes, especially lab technicians, can get this disease. The best way to eliminate the risk is to stop using beryllium. The following resources may help you decide whether you or your staff are in danger of beryllium disease. What is the problem? " Ban beryllium in dentistry ," Amy Ryder, Feb 21, 2001. " Beryllium disease resources ," National Jewish Medical and Research Center, Denver, Colorado. "
Session Beryllium Exposure And Disease In Populations Downstream
848 AM, Screening for beryllium disease among construction trade workers at 924 AM, Cumulative incidence of chronic beryllium disease in a ceramics
http://apha.confex.com/apha/131am/techprogram/session_11742.htm

Extractions: 5060.0: Wednesday, November 19, 2003: 8:30 AM-10:00 AM Oral Beryllium Exposure and Disease in Populations Downstream from Production: Nuclear Weapons Workers and the Public Surrounding Production Plants Learning Objectives: At the conclusion of this session, the participant will be able to (1) identify high risk populations for beryllium disease in nuclear weapons and clean-up workers; (2) understand important aspects of the beryllium exposure/response relationship of proven relevance to occupational health with potential application to community-based exposures; (3) evaluate the adequacy of current monitoring and beryllium disease prevention programs. See individual abstracts for presenting author's disclosure statement and author's information. Organizer(s): Tim Takaro, MD, MPH 8:30 AM Beryllium exposure and disease in populations downstream from production: Nuclear weapons workers and the public surrounding production plants
Nat'l Academies Discovery Engine
A Genetic Marker for Chronic beryllium disease, pp. 293303 read skim srch Immunology of Chronic beryllium disease, pp. 304-312 read skim srch
http://lab.nap.edu/nap-cgi/discover.cgi?term=beryllium disease&restric=NAP&
Los Alamos National Laboratory (LANL): New Los Alamos Tests Will Aid Beryllium W
If we re interested in preventing beryllium disease, we have to consider all the DOE has established its Chronic beryllium disease Prevention Program,
http://www.lanl.gov/news/index.php?fuseaction=home.story&story_id=981
- Toledoblade.com -
She died of beryllium disease, a lung illness that has affected scores of workers locally and nationwide. Government and industry records show that many of
http://www.toledoblade.com/apps/pbcs.dll/artikkel?Dato=19990328&Kategori=SRDEADL

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