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Beryllium Disease: more detail

Chronic beryllium disease and sensitization at a beryllium processing facility.(Research/ Environmental Medicine): An article from: Environmental Health Perspectives by Kenneth Rosenman, Vicki Hertzberg, et all 2005-10-01

Report on the beryllium problem: As discussed at the sixth Saranac Symposium, Saranac Lake, N.Y., 27 September to 3 October, 1947 by W. E Park, 1947

Beryllium toxicity (Case studies in environmental medicine) by Dennis M Green, 1997

lists with details

ATSDR - Public Health Statement: Beryllium
Both the shortterm, pneumonia-like disease and the chronic beryllium Exposure levels associated with acute or chronic beryllium disease are more 100000
http://www.atsdr.cdc.gov/toxprofiles/phs4.html

Extractions: Search Index Home Glossary ... Contact Us CONTENTS What is beryllium? What happens to beryllium when it enters the environment? How might I be exposed to beryllium? How can beryllium enter and leave my body? How can beryllium affect my health? How does it affect children? How can families reduce the risk of exposure to beryllium? Is there a medical test to determine whether I have been exposed to beryllium? What recommendations has the federal government made to protect human health? Where can I get more information? References RELATED RESOURCES ToxFAQ Public Health Statement Toxicological Profile A-Z INDEX A B C D ... J K Q R S T U ... X Y Z ATSDR RESOURCES ToxFAQs ToxFAQs Public Health Statements Toxicological Profiles ... Division of Toxicology September 2002 Public Health Statement for Beryllium CAS# This Public Health Statement is the summary chapter from the Toxicological Profile for beryllium . It is one in a series of Public Health Statements about hazardous substances and their health effects. A shorter version, the ToxFAQs This public health statement tells you about beryllium and the effects of exposure.
Department Of Energy Chronic Beryllium Disease Prevention Program
Chronic beryllium disease Prevention Program. Home. Policy. Guidance. Lessons Learned. Workshops. BeLPT. Alerts. Training. Archives
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Diseases - Chronic Beryllium Disease - National Jewish Medical And Research Cent
beryllium disease Treatment of beryllium disease Living with beryllium disease. © Copyright 2005 National Jewish Medical and Research Center
http://www.nationaljewish.org/disease-info/diseases/occ-med/beryllium/index.aspx
Environ Health Perspect 102-6-7, 1994: Beryllium: A Chronic Problem
Article by Leslie Lang, published in Environmental Health Perspectives in 1994. Discusses uses of this metal in industry, chronic beryllium disease, the possibility of genetic testing for CBD, and the incidence of the disease in the workforce.
http://ehpnet1.niehs.nih.gov/docs/1994/102-6-7/focus.html

Extractions: x-ray tubes Principal uses of beryllium stem from the discovery in the 1920s that an addition of only 2% beryllium to copper results in an alloy six times stronger than copper. beryllium-copper alloys withstand high temperatures, are extraordinarily hard, resistant to corrosion, do not spark, and are nonmagnetic. These alloys are used in many critical moving parts of aircraft engines, in key components of precision instruments, electrical relays, and switches. Beryllium-copper hammers, wrenches, and other nonsparking tools are used in the petroleum industry where sparks from steel might cause explosions. In the electronics industry, including personal computers, Beryllium-copper alloys are found in integrated circuit sockets and electronic connectors. An alloy of 25% beryllium has some limited use in camera shutters. Beryllium-copper alloys are also used in golf clubs, springs, pivots, wheels, pinions, submarine cable housings, and dental prostheses.
Beryllium Support Group
Large collection of information maintained by Denverarea support group for people with chronic beryllium disease.
http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126
Diseases - Treatment Of Beryllium Sensitization And Chronic Beryllium Disease (C
Learn about treatment of beryllium sensitization and chronic beryllium disease (CBD). Is there a treatment? Can they be cured? What medications are used?
http://www.nationaljewish.org/disease-info/diseases/occ-med/beryllium/treatments
Beryllium Support Group
Large collection of information maintained by Denverarea support group for people with chronic beryllium disease.
http://www.beryllium.org/

Extractions: Search Overview This web site was formally launched on March 12, 1996 by Michael Jackson a member of the Beryllium Support Group which meets monthly at the National Jewish Medical and Research Center in Denver, Colorado. The intent is to provide a platform where any other Beryllium Support Group regardless of affiliation or location can freely participate in the presentation of or transfer of information relating to this incurable disease. To provide a forum where anyone around the country or the world can obtain information or provide information they have experienced as a result of this disease. To provide current and historical information on studies and papers relating to this disease. To provide current and historical information relating to the health risks of using beryllium. To provide current and historical information relating to regulations governing the use and control of beryllium. To provide current and historical information of the nature of this disease and its effects on the human body.
Diseases - About Beryllium Disease & Beryllium Lymphocyte Proliferation Test - N
Get information about beryllium disease, a condition that can occur with exposure to beryllium dust or fumes, and the beryllium lymphocyte proliferation
http://www.njc.org/medfacts/beryllium_medfact.html

Extractions: e-mail us Note: This information is provided to you as an educational service of National Jewish. It is not meant to be a substitute for consulting with your own physician. HIPAA Policy Privacy Change Text Size There are 7 related research summaries. The top 5 are shown below. National Jewish Faculty Present Latest Research at AAAAI Meeting National Jewish faculty present the latest findings on asthma, allergens, atopic dermatitis, and the hygiene hypothesis during the annual meeting of the American Academy of Allergy Asthma and Immunology.
Berylliosis - Beryllium Disease - Signs, Symptoms, Treatment, Prevention
beryllium disease / berylliosis is an inflammation of the lungs caused by inhaling dust or fumes containing beryllium. Berylliosis differs from other
http://lungdiseases.about.com/od/berylliumlungdisease/

Extractions: zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a79' About Lung Diseases Locate a Lung Disease Occup / Enviro Lung Disease Berylliosis Lung Diseases Essentials Locate a Lung Disease - START HERE Are You At Risk for Getting Lung Cancer? ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); Sign Up Now for the Lung Diseases newsletter! See Online Courses Search Lung Diseases Beryllium disease / berylliosis is an inflammation of the lungs caused by inhaling dust or fumes containing beryllium. Berylliosis differs from other occupational lung diseases in that even low levels and brief exposure to beryllium can cause berylliosis. Find out more about berylliosis, including signs, symptoms, treatment and prevention of berylliosis. Alphabetical Recent Occupational Lung Disease Screening Quiz There are many occupations that come with great risks for causing lung diseases and respiratory infections. Find out if your job may be hazardous to your health by taking this occupational lung disease screening quiz. Symptoms and Diagnosis of Berylliosis Discover the symptoms, diagnosis, treatment and prognosis of berylliosis.
THE MERCK MANUAL--SECOND HOME EDITION, Beryllium Disease In Ch. 49, Occupational
beryllium disease (sometimes called berylliosis) is a lung inflammation beryllium disease differs from other occupational lung diseases in that at low
http://www.merck.com/mmhe/sec04/ch049/ch049e.html

Extractions: var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Lung and Airway Disorders Chapter Occupational Lung Diseases Topics Introduction Asbestosis Benign Pneumoconioses Beryllium Disease Black Lung Byssinosis Flock Worker's Lung Gas and Chemical Exposure ... Silicosis Beryllium Disease Buy The Book Print This Topic Email This Topic Pronunciations asbestosis berylliosis beryllium byssinosis ... silicosis Beryllium disease (sometimes called berylliosis) is a lung inflammation caused by inhaling dust or fumes that contain beryllium. In the past, beryllium was commonly mined and extracted for use in the electronics and chemical industries and in the manufacture of fluorescent light bulbs. Today, it is used mainly in the aerospace industry and in beryllium-aluminum castings. Besides workers in these industries, a few people living near beryllium refineries also have developed beryllium disease.
What Is Chronic Beryllium Disease?
Chronic beryllium disease, or CBD, is an inflammation in the lungs that can occur when a person is exposed to respirable beryllium fumes, dusts or powder,
http://www.befacts.com/cbd/

Extractions: Chronic beryllium disease, or CBD, is an inflammation in the lungs that can occur when a person is exposed to respirable beryllium fumes, dusts or powder, and subsequently demonstrates an allergic reaction to beryllium. CBD is an occupational disease that may occur in the manufacture of metallic beryllium, beryllium oxide ceramic, or alloys containing beryllium. It was first identified more than 50 years ago. Not everyone who is exposed to beryllium fumes, dusts or powder will develop CBD; most people do not . Researchers now believe that the tendency to develop CBD is genetically determined and results from an allergic sensitivity. Some individuals develop an allergy to beryllium upon exposure and are, therefore, more likely to develop CBD. Some people who are diagnosed with CBD do not develop clinical symptoms at all. In others, the disease can lead to clinical symptoms that include scarring and damage of lung tissue, causing shortness of breath, wheezing and/or coughing. Extreme cases of CBD can cause disability or death. The course of the disease can range from a few years to decades. Home What is Beryllium?
The Natural History Of Beryllium Sensitization And Chronic Beryllium Disease
Key words beryllium, chronic beryllium disease, granuloma, cellmediated immunity, lymphocyte, natural history, lung disease, pulmonary, immunology,
http://ehpnet1.niehs.nih.gov/docs/1996/Suppl-5/newmanabs.html

Extractions: Environmental Health Perspectives Supplements Volume 104, Number S5, October 1996 The Natural History of Beryllium Sensitization and Chronic Beryllium Disease Lee S. Newman, Jenifer Lloyd, and Elaine Daniloff Departmet of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado; Department of Medicine and Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado Abstract With the advent of in vitro immunologic testing, we can now detect exposed individuals who are sensitized to beryllium and those who have chronic beryllium disease (CBD) with lung pathology and impairment. Earlier detection and more accurate diagnostic tools raise new questions about the natural history of sensitization and granulomatous disease. Preliminary data suggest that early detection identifies people who are sensitized to beryllium and that these individuals are at risk for progressing into clinical disease. This article discusses the historical, recent, and ongoing studies germane to our understanding of CBD natural history, including the immunologic and inflammatory basis of the disease, the environmental and host risk factors for disease progression, biological markers of disease severity and activity that may help predict outcome, and the implications for broad-based workplace screening to identify patients at the earliest stages of beryllium sensitization and disease.
Chronic Beryllium Disease: Diagnosis And Management
Chronic beryllium disease Diagnosis and Management, beryllium, granuloma, restrictive lung disease, occupational lung disease, immunology, cellmediated
http://ehpnet1.niehs.nih.gov/docs/1996/Suppl-5/rossmanabs.html

Extractions: Chronic beryllium disease is predominantly a pulmonary granulomatosis that was originally described in 1946. Symptoms usually include dyspnea and cough. Fever, anorexia, and weight loss are common. Skin lesions are the most common extrathoracic manifestation. Granulomatous hepatitis, hypercalcemia, and kidney stones can also occur. Radiographic and physiologic abnormalities are similar to those in sarcoidosis. While traditionally the pathologic changes included granulomas and cellular interstitial changes, the hallmark of the disease today is the well-formed granuloma. Immunologic studies have demonstrated a cell-mediated response to beryllium that is due to an accumulation of CD4 T cells at the site of disease activity. Diagnosis depends on the demonstration of pathologic changes (i.e., granuloma) and evidence that the granuloma was caused by a hypersensitivity to beryllium (i.e., positive lung proliferative response to beryllium). Using these criteria, the diagnosis of chronic beryllium disease can now be made before the onset of clinical symptoms. Whether, with early diagnosis, the natural course of this condition will be the same as when it was traditionally diagnosed is not known. Currently, corticosteroids are used to treat patients with significant symptoms or evidence of progressive disease.
Beryllium Disease
NJMRC Facts About beryllium disease - Learn about the symptoms and beryllium disease Facts Sponsored by Golomb Honik - The beryllium disease Website
http://www.health-nexus.com/beryllium_disease.htm

Extractions: The #1 Health information site Health-Nexus.Net Health-Nexus.Org Home ... Up Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Beryllium Disease Natural History of Beryllium Sensitization and Chronic Beryllium Disease A medical article about the early detection of beryllium sensitization and chronic beryllium disease. Includes recent studies .... National Beryllium Support Group Provides fact sheets and articles about the incurable disease, plus details about government regulations regarding exposure to beryllium. ... evident among workers, who when exposed to beryllium fumes and dust, can also develop Chronic Beryllium Disease, or CBD. ...
Chronic Beryllium Disease And Other Beryllium-Related Diseases And Medical Issue
Describes Berylliumrelated diseases and other Beryllium-related medical issues, including chronic beryllium disease or berylliosis.
http://www.chronicberylliumdisease.com/medical/med_bediseases.htm
Beryllium Exposure Medical Issues: Detection
Describes how to test for and detect berylliumrelated diseases including chronic beryllium disease or berylliosis.
http://www.chronicberylliumdisease.com/medical/med_test.htm

Extractions: Medfacts, National Jewish and Medical Research Center The BeLPT identifies beryllium sensitization earlier and better than any other clinical test presently available, according to various studies ( Significance of the Blood Lymphocyte Proliferation Test, Environmental Perspectives ). It is used to improve clinical diagnostic accuracy and to correct mistaken diagnoses. Furthermore, it is very specific and has high predictive value for CBD. Printer friendly version home beryllium defined exposure ... about us This web site is sponsored by the law firm of for educational purposes. Please see our and
Berylliosis
Acute beryllium disease; Beryllium Granulomatosis; Beryllium Pneumonosis There are two forms of berylliuminduced lung disease acute and chronic.
http://my.webmd.com/hw/health_guide_atoz/nord481.asp

Extractions: Berylliosis is a form of metal poisoning caused by inhalation of beryllium dusts, vapors, or its compounds or implantation of the substance in the skin. The toxic effects of beryllium most commonly occur due to occupational exposure. Beryllium is a metallic element used in many industries, including electronics, high-technology ceramics, metals extraction, and dental alloy preparation.
Beryllium - Beryllium Lawyer, Beryllium Attorney, Beryllium Law
Chronic beryllium disease is an inflammation in the lungs that can occur when a person is exposed to beryllium fumes, dusts or powder, and subsequently
http://www.berylliumhelpcenter.org/ChronicBerylliumDisease.html
Beryllium - Beryllium Lawyer, Beryllium Attorney, Beryllium Law
beryllium disease primarily affects the lungs. The disease occurs when people inhale beryllium dust or fumes. Skin disease with poor wound healing and rash
http://www.berylliumhelpcenter.org/What_is_Beryllium.html
Unmasking The Mysteries Of Chronic Beryllium Disease
Beryllium is a unique lightweight metal used in nuclear weapons and, in the commercial sector, for telescope mirrors, golf clubs and a variety of other
http://www.eurekalert.org/features/doe/2001-06/danl-utm061302.php

Extractions: Text-Only Privacy Policy Site Map Beryllium is a unique lightweight metal used in nuclear weapons and, in the commercial sector, for telescope mirrors, golf clubs and a variety of other applications. While solid beryllium and beryllium alloys are safe, fine particulate beryllium is hazardous if inhaled. In certain individuals, breathing microscopic beryllium particles can lead to Chronic Beryllium Disease (CBD), sometimes called berylliosis. CBD is a long-duration, allergic-type lung response that can make the sufferer abnormally weak and is sometimes fatal. Research into beryllium health effects in the Bioscience Division at Los Alamos National Laboratory center on identifying worker sensitivity and increased risk caused by genetic factors. Only a small percentage of people exposed to beryllium become sensitized to it, meaning they experience an immune-system reaction to exposure. In addition, it appears that not everyone who is sensitized develops CBD. A team led by Bioscience Division researcher Babs Marrone has devised an improved Lymphocyte Proliferation Test, or LPT, a blood test that can identify sensitized individuals. The researchers also have found genetic markers that indicate increased susceptibility.

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