1. Von Willebrand Disease Offers information about von willebrand disease. Includes the types, the symptoms, treatment, and heredity. http://www.hemophilia.ca/en/2.2.php

Von Willebrand Disease Von Willebrand Disease Introduction Types of Von Willebrand Disease Heredity Symptoms ... Precautions Researched and written by David Page Reviewed by David Lillicrap, M.D., FRCPC Personal Stories Related Articles

2. JRTCA - Jack Russell - Medical: Canine Von Willebrand's Disease Information on this disease from the Jack Russell Terrier Club of America. http://www.terrier.com/breed/vonwill.php3

Preserve, Protect and Work the Jack Russell Jack Russell Terrier Club of America Home JRTCA Breed Rescue ... Medical Menu Von Willebrand's Disease History Lesson Breed Standard Pictorial Guide Bad Dog Talk ... Certificates JRT Books 21 Days to a Trained Dog View All Books Please report "puppy for sale", kennel or otherwise objectionable links to the webmaster. Gift Store Join Today! Web Site Survey Canine Von Willebrand's Disease Diagnosis can be performed by measurement of plasma concentrations of vWF. TESTING SHOULD BE DONE AT AN EARLY AGE SINCE THE DISORDER OFTEN DIMINISHES WITH AGE, CAUSING FALSE-NEGATIVE TEST RESULTS IN OLDER ANIMALS. Additional screening tests such as bleeding times or platelet agglutination assays can also be performed. Precautions should be taken before surgery, so it is important to let your veterinarian know of bleeding problems in the past. Different breeds exhibit different variations of the disease, and some individual animals appear to "acquire" vWD. While the bulk of the information available is based upon purebred dogs, the disease is not unknown in mixed breeds. The total number of breeds affected by vWF exceeds 50. The disease also appears in cats, pigs, horses, and humans. Human variants of vWD are broken into three main types which can be used to describe canine vWD. Type I vWD is characterized by a low concentration of normally structured protein. In screening studies done at Cornell over a period of years (1982-1992), percentages of dogs of some breeds tested as carrying the disease, and with concentrations of vWF less than 50% of standard (considered to be at risk) were the following breeds: Corgi, Poodle (std. and min), Scottie, Golden Retriever, Doberman, Sheltie, Akita, Cairn.

3. OBGYN.net - Von Willebrand Q And A Specific information on how this hereditary disease impacts women. http://www.obgyn.net/english/pubs/announcements/vwd_q_a.htm

von Willebrand Disease Information Sheet A Brief History von Willebrand disease (vWD) is thought to be the most common hereditary bleeding disorder, affecting up to 3% of the U.S. population. vWD was first recognized in 1925 by Erik von Willebrand, a Finnish physician, who described a new type of bleeding disorder in inhabitants of the C land Islands. Using simple laboratory equipment, von Willebrand observed that his patients had an abnormality in blood platelet function. We now know that their platelets behaved abnormally because their plasma lacked von Willebrand factor. von Willebrand factor helps platelets adhere to damaged blood vessels to form a platelet plug, an integral aspect of hemostasis. von Willebrand factor also serves as a carrier protein for plasma factor VIII. vWD affects men and women in equal numbers, but it does not affect them equally. Because the most common symptoms of vWD in women (heavy and prolonged menstrual periods) are often misunderstood to be a gynecologic rather than a hematologic problem, the risk of misdiagnosis and undertreatment poses a greater health concern for women than it does for men. vWD in its mildest form can cause an inconvenience for women. They may require pre-treatment for certain dental procedures, surgery, or child birth. But for women with moderate to severe vWD, the bleeding disorder can be debilitating and potentially life threatening if undiagnosed and untreated.

4. Matt Klimshuk's Home Page Information on von willebrand s Disease and links to von willebrand s and Hemophilia sites. http://www.mindspring.com/~mattrk/

"Information is Power" Providing Information on von Willebrand's Disease Go To Personal Information What Is Von Willebrand's Disease? Von Willebrand's Disease (vWD) is not a disease at all, but the most common genetic disorder in the world (classic hemophilia is more well known due to its connection with the royal families of Europe). In fact, vWD is times more common than classic hemophilia! It was discovered by a Finnish doctor in the 1920s, who named it after himself and called it a disease. Later, Dr. von Willebrand discovered in truth that the illness was linked to a missing blood factor, which assists with the clotting of blood. He named the factor after himself as well - von Willebrand's Factor (vWF). The disorder is not sex linked (autosomal), meaning that both men and women can have it, but some can be carriers only and not manifest any of the symptoms. VWD occurs when the body makes either inferior vWF or none at all. Other blood factors can be short-changed as well. Generally, vWD is divided into three types: Type I (mild), Type II (Medium) and Type III (severe). The lower the type, the less the symptoms will occur and the less strenuous they will be. What Are the Symptoms?

5. Sheffield University VWF Homepage Genetic mutation and polymorphism database for human von willebrand factor with other useful information for researchers, from the University of Sheffield, UK. http://www.sheffield.ac.uk/vwf/

Maintained at the University of Sheffield, United Kingdom ISTH SSC VWF Information Homepage Supported by Up-to-date databases of point mutations, insertions, deletions, and polymorphisms found in the gene for human von Willebrand Factor. Fast link: Mutations Polymorphisms Nomenclature VWF Sequences VWD Diagrams Useful links Database submission References Downloads Searches Sponsor Patient information Credits Please select one of the following links: Summary Summary of mutations in the human VWF mutation database (June 2004) Mutations Mutations in the human VWF gene sorted by nucleotide number and by association with type of von Willebrand disease (VWD) Polymorphisms Polymorphisms in the human VWF gene Nomenclature Current nomenclature recommended by the ISTH VWF SSC Updated VWF Sequences Amino acid, cDNA and genomic DNA links with Mancuso genomic and pseudogene sequences. Also links to VWF sequences of other species VWD A brief description of the types of von Willebrand Disease (VWD) Diagrams Figures of the VWF gene, mRNA and protein (including binding domains) and example multimer gels for VWD type 2 defects Links Links to other useful web sites New Mutations/Polymorphisms How to submit a new mutation or polymorphism to the database manager References Alphabetical list of VWF mutation and polymorphism references in the database Downloads Useful VWF downloads, including PDB files containing the structure of VWF A1 and A3 domains to be viewed in Rasmol

6. Von Willebrand Disease How to test and diagnose this bleeding disorder. http://www.awsaclub.com/healthgenetics/von.htm

von Willebrand Diease Author: Judy Huston When I started asking breeder friends of mine about vWF, most stated versions of the following: Their vet advised them the test was inaccurate so there was not much point in doing it. If properly performed, the test is NOT unreliable – but a commercial company marketing a DNA marker test for certain breeds (not GSD), has claimed so. Their worth has never been published and current literature no longer claims that blood test is "unreliable" – good thing as it is unprofessional and ……. They stated the disease is not in their lines so again there is no reason to do the test. The Type I disease is much more common than the other types of vWD and has been recognized in more than 50 breeds to date. Breeds with a high prevalence of the vWD gene include the Doberman Pinscher (80%), Scottish Terrier, Minature Poodle, Pembroke Welsh Corgi, German Shepherd (vWD Gene 15 to 80%), Rottweiler, Standard and Toy Manchester Terrier, Keeshond, and the Standard and Miniature Dachschund. Although relatively few have severe problems and even fewer die from it, many animals are affected by vWD. Bleeding typically involves mucosal surfaces. The bleeding episodes are worsened by physical, emotional, and physiological stresses as well as by other concomitant diseases. Typical clinical signs include: recurrent gastrointestinal hemorrhage with or without diarrhea; recurrent hematuria; existaxis; bleeding from the gums, vagina, or penis; lameness that mimics eisinophilic panosteitis; stillbirths or neonatal deaths ("fading pups") with evidence of bleeding at necropsy; prolonged bleeding at estrus or after whelping; bruises or hematomas on the surface of the body, limbs, or head; excessive umbilical cord bleeding at birth; and excessive bleeding from toenails cut too short or after tail docking, ear cropping, and dew claw removal. Affected dogs may bleed to death from surgical procedures.

7. Von Willebrand's Disease Article on von willebrand's disease identifying breeds most commanly affected as well as symptoms and treatment. http://www.animalforum.com/dbreed/medvonwill.htm

Check out our suggested books for dog owners Von Willebrand's disease By Brandon Brooks, DVM V on Willebrand's Disease (vWD) is both an inherited and acquired condition. Breeds most commonly inheriting the trait for this disease are Doberman Pinschers, standard poodles, Pembroke Welsh Corgis, Scotties, Shelties and golden retrievers, among others. This disease, which is a deficiency in a certain clotting factor (a blood protein), can also be caused by other conditions such as hypothyroidism, estrus, pregnancy, infections and certain drugs including NSAIDs like aspirin. vWD is the most common inherited bleeding disorder in dogs, and it is a recessive trait that can affect males and females equally. These dogs lack the ability to manufacture von Willebrand's factor, or Factor VIII (8), a blood protein essential in the clotting cascade. With its absence, blood cannot clot properly and many affected animals will spontaneously bleed. Without the ability to clot reliably, these animals are at serious risk of bleeding to death. Sometimes problems are noted first when the animal bleeds spontaneously, such as a nosebleed. vWD can also be picked up during things like a nail trim, and if one of the nails is "quicked" it doesn't stop bleeding, even with much application of styptic powder. It can also be noticed at the time of spaying or neutering, or during examination when blood is drawn for a heartworm test. Bleeding can also be noted in vomitus or in the stool, and the presence of a dark tarry stool indicates bleeding in the upper GI tract.

8. All About Bleeding A resource for education, guidance and support for people who have or suspect they have von willebrand disease. Offers personalized tools, information resources, and community support. http://www.allaboutbleeding.com

Sign In Search: Home Journal VWD and You Family Tree ... Ask an Expert Hello Guest Members can Sign In Here to allaboutbleeding Tell A Friend Sign In Enroll Now! VWD and You Home ... living better with VWD Discover allaboutbleeding's wealth of information on VWD. Visit VWD and You VWD Symptom Checklist Some symptoms commonly experienced by people living with VWD are: Easy Bruising Frequent Nosebleeds Heavy Periods Prolonged Bleeding To Find Out More, visit Understanding VWD or explore VWD And You website poll What do you find to be the best information resource for VWD? Healthcare Professional The Web Friends / Family Printed Materials Other Please Specify: View Answers treatment center Locate your nearest Treatment Center: Select A State Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Puerto Rico Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Alberta British Columbia Manitoba New Brunswick Newfoundland Nova Scotia Ontario Prince Edward Island Quebec Saskatchewan Learn More about Hemophilia Treatment Centers All About Bleeding is a resource dedicated to increasing awareness about von Willebrand Disease (VWD). You'll find information about von Willebrand disease, a community of people sharing their experiences, plus an expert to answer your questions.

9. Welkom Bij Finlandsite Over de ontdekker van de gelijknamige aandoening. http://www.archiefstartpunt.nl/finlandsite/willebrand.htm

document.write(''); Hier vindt u informatie over von Willebrand, ontdekker van de Ziekte van Willebrand Deze pagina is verplaatst. Als er niets gebeurt, klik dan hier om door te gaan Glebbeek-Internet Gratis teller

10. Tesi Di Laurea - Malattia Di Von Willebrand: Espressione In Vitro Di Varianti Mo Estratto di una tesi di laurea su questa patologia emorragica ereditaria. http://www.tesionline.it/default/tesi.asp?idt=9740

11. Page Not Found Information including Pediatric studies. http://www.beckmancoulter.com/Coulter/Techpubs/Pediatric-Profiles/vWD.asp

var brname = ""; Products Customer Support Resource Center Contact Us ... Our Company Page Not Found The page you requested was not found. It may have moved, or it may no longer exist. Did you bookmark the page? The URL may have changed. Use the search feature in the upper right corner of this page to relocate the page and replace your bookmark. Did you type the URL into the address/location bar correctly? Check your spelling, capitalization and punctuation and try again. Did a link in the Beckman Coulter website bring you here? If so, please send us your comments . On the comments form, select "Contact the WebMaster" under the column "Non Product Related Questions". If available, please specify the name of the link you clicked, the URL of the page, or how you navigated there. Home Products Customer Support Resource Center ... Printing Instructions

12. Matt Klimshuk - Von Willebrand's Disease Information on von willebrand's Disease and links to von willebrand's and Hemophilia sites. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Von Willebrand Disease: Introduction von willebrand Disease (VWD) is the most common bleeding disorder that people have. (See Types of von willebrand Disease.) All the different types are http://www.hemophilia.ca/en/2.2.1.php

Von Willebrand Disease: Introduction Von Willebrand Disease Introduction What is Von Willebrand Disease? How does blood clot normally? How does VWD affect the normal clotting of blood? How common is Von Willebrand Disease? ... How serious is Von Willebrand Disease? What is Von Willebrand Disease? Von Willebrand Disease (VWD) is the most common bleeding disorder that people have. In fact, it is not a single disease, but a family of related diseases. (See Types of Von Willebrand Disease.) All the different types are caused by a problem with the Von Willebrand Factor (VWF). This is a protein in blood which is necessary for proper blood coagulation, or clotting. The genes that make VWF are " turned on " in two cell types in the body: the lining cells of blood vessels (endothelial cells) and platelets. When there is not enough VWF in the blood, or when it does not work the way it should, the blood takes longer to clot. How does blood clot normally? Blood is carried throughout the body within a network of blood vessels. When tissues are injured, damage to a blood vessel may result in leakage of blood through holes in the vessel wall. The vessels can break near the surface, as in a cut. Or they can break deep inside the body, making a bruise or an internal hemorrhage. Platelets are small cells circulating in the blood. Each platelet is less than 1/10,000 of a centimetre in diameter. There are 150 to 400 billion platelets in a normal litre of blood. The platelets play an important role in stopping bleeding and beginning the repair of injured blood vessels.

14. All About Bleeding A resource for education, guidance and support for people who have or suspect they have von willebrand disease. Offers personalized tools http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. OBGYN.net - Von Willebrand Q And A von willebrand disease (vWD) is thought to be the most common hereditary bleeding disorder, affecting up to 3% of the U.S. population. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. MedlinePlus Medical Encyclopedia: Von Willebrand’s Disease von willebrand s disease is a hereditary bleeding disorder caused by a von willebrand factor helps platelets to stick to the blood vessel wall and to http://www.nlm.nih.gov/medlineplus/ency/article/000544.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Von Willebrand’s disease Contents of this page: Illustrations Definition Causes, incidence, and risk factors Symptoms ... Calling your health care provider Illustrations Blood clot formation Blood clots Definition Return to top Von Willebrand's disease is a hereditary bleeding disorder caused by a deficiency of von Willebrand factor. Von Willebrand factor helps platelets to stick to the blood vessel wall and to each other, which is necessary for normal blood clotting. Causes, incidence, and risk factors Return to top Von Willebrand's disease is the most common hereditary bleeding disorder. It affects both sexes approximately equally. Most cases are mild, and bleeding may occur after a surgical procedure or tooth extraction. The condition is worsened by the use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Bleeding may decrease during pregnancy. The disease is very common, affecting at least 1% of the population. A family history of a bleeding disorder is the primary risk factor. In women with heavy or prolonged menstrual bleeding, Von Willebrand's is more common in Caucasian women than African American women. Symptoms Return to top Nose bleeds Bleeding of the gums Abnormal menstrual bleeding Bruising Skin rash Signs and tests Return to top Normal platelet count Prolonged bleeding time Reduced von Willebrand factor level Reduced platelet aggregation ( platelet aggregation test Ristocetin co-factor is reduced

17. Von Willebrand's Disease von willebrand's disease should affect factor VII only, so it is should only show up as an increase in the APTT time. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. EMedicine - Von Willebrand Disease : Article By John D Geil, MD von willebrand Disease Although referred to as a single disease, von willebrand disease (vWD) is in fact a family of bleeding disorders caused by an http://www.emedicine.com/ped/topic2419.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Hematology Von Willebrand Disease Last Updated: August 18, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: vWD AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: John D Geil, MD , Associate Professor, Department of Pediatrics, University of Kentucky Children's Hospital John D Geil, MD, is a member of the following medical societies: American Academy of Pediatrics , and American Society of Pediatric Hematology/Oncology Editor(s): J Martin Johnston, MD , Consulting Staff, Department of Pediatrics, Division of Hematology-Oncology, Saint Luke's Mountain States Tumor Institute; Robert Konop, PharmD , Director of Drug Programs and Utilization; James L Harper, MD , Associate Chair for Medical Education in Pediatrics, Associate Professor of Pediatric Hematology-Oncology, University of Nebraska Medical Center; Samuel Gross, MD

19. National Hemophilia Foundation For All Bleeding And Clotting News, research, programs and resources. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

20. EMedicine - Von Willebrand Disease : Article By Eleanor S Pollak, MD von willebrand Disease In 1926, Erik von willebrand first reported an autosomally inherited mucocutaneous bleeding disorder in a large family from the http://www.emedicine.com/med/topic2392.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology von Willebrand Disease Last Updated: August 18, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: von Willebrand disease, von Willebrand's disease, vWD, VWD, von Willebrand factor, VWF, vWF, mucocutaneous bleeding disorder, primary hemostasis impairment, bleeding disorder, hematological disorder AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Eleanor S Pollak, MD , Associate Director of Special Coagulation, Assistant Professor, Department of Pathology and Laboratory Medicine, Section of Hematology and Coagulation, University of Pennsylvania Coauthor(s): Steven Stein, MD , Assistant Professor, Department of Medicine, Division of Hematology/Oncology, University of Pennsylvania Eleanor S Pollak, MD, is a member of the following medical societies:

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 1     1-20 of 112    1  | 2  | 3  | 4  | 5  | 6  | Next 20