21. Von Hippel-Lindau Disease - Wikipedia, The Free Encyclopedia (Redirected from Von HippelLindau syndrome). von hippel-lindau disease (VHL) is a rare inherited genetic condition involving the abnormal growth of tumors http://en.wikipedia.org/wiki/Von_Hippel-Lindau_syndrome

22. Von Hippel-Lindau Disease - Wikipedia, The Free Encyclopedia von hippellindau disease (VHL) is a rare inherited genetic condition involving the abnormal growth of tumors in parts of the body which are particularly http://en.wikipedia.org/wiki/Von_Hippel-Lindau_disease

You did it! Over US$240,000 was donated in the 21-day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Von Hippel-Lindau disease From Wikipedia, the free encyclopedia. Von Hippel-Lindau disease (VHL) is a rare inherited genetic condition involving the abnormal growth of tumors in parts of the body which are particularly rich in blood supply. Contents Features Types Genetics History ... edit Features Features of VHL are: angiomatosis - little knots of capillaries in various organs. These tend to be cavernous hemangiomas, which are sharply defined, sponge-like tumors composed of large, dilated, cavernous vascular spaces. hemangioblastomas - tumors of the central nervous system (CNS, especially the cerebellum ). These tumors, whether benign (usual) or malignant (rarer), may cause problems, for example angiomas in the brain or spinal cord may press on nerve or brain tissue. As an angioma grows, the walls of the blood vessels may weaken and leak, causing damage to surrounding tissues. Blood leakage from angiomas in the retina can interfere with vision.

23. Von Hippel-Lindau Disease von hippellindau disease, an Inherited Cancer Syndrome. Dr. James Gnarra One is kidney cancer associated with von Hippel-Lindau (VHL) disease. http://www.medschool.lsuhsc.edu/genetics_center/louisiana/article_vonhippellinda

24. Von Hippel-Lindau Disease, An Inherited Cancer Syndrome One is kidney cancer associated with von HippelLindau (VHL) disease. By analyzing genetic markers in many VHL patients, it was discovered in the late http://www.medschool.lsuhsc.edu/genetics_center/louisiana/article_vonhippellinda

25. Von Hippel-Lindau Disease von hippellindau disease Von Hippel-Lindau Syndrome Family Alliance NINDS von hippel-lindau disease Information Page. Author(s) Nuhad D. Dinno, MD. http://www.5mcc.com/Assets/SUMMARY/TP0990.html

von Hippel-Lindau disease DESCRIPTION: One of the neurocutaneous syndromes (phakomatoses). A familial cancer syndrome with predisposition to ocular and CNS hemangioblastomas, renal cell carcinoma, and pheochromocytomas. Prognosis is variable. CAUSES: Autosomal dominant with gene locus at chromosome region 3p25-3p26 Synonyms: Cerebelloretinal hemangioblastomatosis Angiophakomatosis retinae et cerebelli ICD-9-CM: 759.6 other hamartoses, NEC Web references: Von Hippel-Lindau Syndrome Family Alliance Von Hippel-Lindau Syndrome Family Alliance NINDS von Hippel-Lindau Disease Information Page Author(s): Nuhad D. Dinno, MD

26. Kprones VHLKpr10010 von hippellindau disease affecting 43 members of a single kindred Somatic inactivation of the VHL gene in von hippel-lindau disease tumors. http://www.infobiogen.fr/services/chromcancer/Kprones/VHLKpr10010.html

Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumours ... NA Von Hippel-Lindau Identity Note Von Hippel-Lindau (VHL) disease is a hereditary devastating cancer syndrome, predisposing to the development of various benign and malignant tumours (Central Nervous System [CNS] and retinal hemangioblastomas, endolymphatic sac tumours, renal cell carcinoma (RCC) and/or renal cysts, pheochromocytomas, pancreatic cysts and neuroendocrine tumours, endolymphatic sac tumours, epididymal and broad ligament cystadenomas). VHL disease is the first cause of hereditary kidney cancer Inheritance an autosomal dominant disorder with high penetrance (increasing with age: 97% by age 60 yrs) but variable expressivity (with phenotype/genotype correlations); frequency is estimated at about 2.5/10 ; neomutations represent about 20% of cases. Clinics Phenotype and clinics onset of the disease usually occurs between 18 and 30 yrs, often with retinal or cerebellar hemangioblastomas, but can also manifests in children, especially by retinal hemangioblastomas and pheochromocytoma. Central nervous system (CNS) hemangioblastomas occur in 60-80% of patients (infratentorial localisation in 60 % of cases, intraspinal in 30-40%; supratentorial in 1%). Multiple tumours are frequent (hemangioblastomatosis).

27. Hippel-Lindau Disease (www.whonamedit.com) Also known as von hippellindau disease,Hippel s disease,Hippel s syndrome,Hippel-Czermak syndrome,Hippel-Lindau disease,Lindau s disease,Lindau s tumour http://www.whonamedit.com/synd.cfm/2057.html

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. A recommendation: Hypography is an open community about science and all things related Hippel-Lindau disease Also known as: Von Hippel-Lindau disease Hippel's disease Hippel's syndrome Hippel-Czermak syndrome Hippel-Lindau disease Lindau's disease Lindau's tumour von Hippel-Lindau syndrome Lagleyze-von Hippel disease Synonyms: Angiomatosis retinae, angiomatosis retinae cystica, angiophacomatosis, angioreticuloma cerebelli, cerebello retina angiomatosis, cerebelloretinal haemangioblastomatosis, cerebroretinal syndrome, haemangioblastomatosis, hereditary haemangiomatosis of the central nervous system, retinal angiomatosis, retinal capillary hamartoma, retinocerebral angiomatosis, viscerocystic retinoangiomatosis syndrome. Associated persons: Johann Nepomuk Czermak Eugen von Hippel Pedro Lagleyze Arvid Vilhelm Lindau Description: A syndrome characterised by angiomatosis of the retina, haemangioblastoma of the cerebellum and walls of the fourth ventricle, commonly associated with polycystic lesions of the kidney and pancreas. Inheritance is autosomal dominant with variable clinical expression. Very long list of ocular features. The syndrome is transmitted as an autosomal dominant trait with varying expression, the symptoms not being apparent until the third decade of life.

28. VHL - Von Hippel-Lindau Syndrome - Cancer GeneticsWeb von HippelLindau (VHL) disease is a hereditary cancer syndrome characterised by the Molecular genetic analysis of von hippel-lindau disease. http://www.cancerindex.org/geneweb/VHL.htm

Cancer Genetics Web www.cancer genetics.org VHL ; Von Hippel-Lindau Syndrome (3p26-p25) VHL Menu Summary Information - VHL Gene Database Entries for VHL Other VHL Related Resources von Hippel-Lindau disease ... Feedback / suggest a new topic for VHL Search: Summary Information VHL; Von Hippel-Lindau Syndrome Location: Return to VHL Contents Gene Database Entries for VHL OMIM GeneCard (Weizmann Institute) Human Gene Mutation Database (Cardiff, UK) Tumor Gene Database Swiss-Prot Locus Link UniGene ... Nomenclature (search for VHL) Return to VHL Contents Other Related Resources von Hippel-Lindau Syndrome and the VHL Gene (National Center for Biotechnology Information) an overview of von Hippel-Lindau Syndrome and the VHL gene. Links to other gene databases. VHL Mutations Database (Universal Mutation Database, France) Medline Search: VHL (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Medline Search: Von Hippel-Lindau Syndrome (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND VHL[TI] (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to VHL Contents von Hippel-Lindau disease von Hippel-Lindau (VHL) disease is a hereditary cancer syndrome characterised by the development of vascular tumours of the central nervous system and retina, renal carcinomas, pheochromocytomas, pancreatic islet cell tumours, endolymphatic sac tumours, and benign cysts affecting a variety of organs. VHL is a dominantly inherited syndrome associated with germline mutations of the VHL tumour suppressor gene located on chromosome 3p25. Inactivation or loss of the remaining wild-type allele in a susceptible cell may lead to tumour development.

29. Von Hippel-Lindau Disease von hippellindau disease, research index site with links for disability users, 1000 s of search engines and with live java games, chat s, kids internet, http://www.ability.org.uk/von.html

"see the ability, not the disability" You to can help support the Ability Project by: Our Aims ... Z von Hippel-Lindau disease VHL Family Alliance - A home page providing information about von Hippel-Lindau disease, a rare familial cancer, sponsored by a non-profit support organization. Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

30. Von Hippel-Lindau Disease von hippellindau disease Updated April 4, 2004 NOAH Genetic Diseases Specific Conditions von hippel-lindau disease http://www.noah-health.org/en/genetic/conditions/hippel.html

Skip navigation About NOAH Help English Spanish Both Advanced NOAH Genetic Diseases Change text size: von Hippel-Lindau Disease Updated: April 4, 2004 The VHL Handbook VHL Family Alliance von Hippel-Lindau Disease National Institute on Neurological Disorders and Stroke von Hippel-Lindau Syndrome NCBI von Hippel-Lindau Syndrome Gene Tests-Gene Clincs Researched by NOAH Contributing Editor: NOAH Team NOAH Genetic Diseases Specific Conditions > von Hippel-Lindau Disease Health Topics Index A to Z Page of the Month Advanced Search ... Feedback

31. Search Result For "Von Hippel-Lindau Disease" NOAH pages containing von hippellindau disease . Displaying 1-5 of 680 The VHL Handbook; von hippel-lindau disease; von Hippel-Lindau Syndrome; http://www.noah-health.org/search/results.php?lang=1&keyword=Von Hippel-Lindau D

32. Von Hippel-Lindau Disease - Swedish Medical Center, Seattle, Washington von hippellindau disease - Swedish Medical Center, Seattle, Washington. http://www.swedish.org/14639.cfm

PDF Version Search Send-to-Friend Health Library Home ... Conditions InBrief Von Hippel-Lindau Disease Pronounced: VON HIP-el LIN-do by Laurie Rosenblum, MPH Definition Causes Risk Factors ... Prevention Definition von Hippel-Lindau disease (VHL) is a rare genetic disorder (affecting approximately 1 in 36,000 people) in which some blood vessels grow in an abnormal way and cause tumors in parts of the body that are rich in blood vessels. Causes VHL is caused by an abnormal change in a gene. This gene mutation, which is passed on from parent to child, results in the uncontrolled growth of some capillaries. Capillaries are tiny blood vessels. Instead of growing normally like the branches of a tree, these blood vessels grow in a small knot. The knot forms a growth or tumor called an angioma or a hemangioblastoma, most commonly in the eye and brain. VHL is also associated with other tumors, some of which are cancerous, and abnormal cysts throughout the body. Risk Factors A risk factor is something that increases your chances of getting a disease or condition. The only known risk factor for VHL is having family members with VHL. Symptoms There is wide variation in the age at which VHL begins, the organs where problems occur, and the types and severity of symptoms. These differences occur even among members of the same family.

33. Neurosurgery - Brain Tumor Program von hippellindau disease (VHL) is characterized by hemangioblastomas of the brain, spinal cord, and retina; renal cysts and renal cell carcinoma; http://www.brighamandwomens.org/neurosurgery/Patient/VHLclinic.asp

home find a BWH doctor request an appointment about BWH ... Neurosurgery Home Neurosurgery Von Hippel-Lindau Disease (VHL) Program Peter M. Black , M.D., Ph.D., Neurosurgery, BWH/CH Lloyd P. Aiello , M.D., Ph.D., Ophthalmology, Beetham Eye Institute, Joslin Diabetes Center Umberto De Girolami , M.D., Neuropathology, BWH/CH Liangge Hsu , M.D., Neuroradiology, BWH Robert Jyung , M.D., Otolaryngology, BWH/MEEI Ursula Kaiser , M.D., Endocrinology, BWH Mark W. Kieran , M.D., Ph.D., Pediatric Neuro-Oncology, DFCI Bruce R. Korf, M.D., Ph.D., Genetics/Harvard-Partners Laboratory of Molecular Medicine Scott Pomeroy , M.D., Neurology/Neuro-Oncology, CH Naren R. Ramakrishna , M.D., Ph.D., Radiation Oncology, BWH Julian Seifter , M.D., Nephrology, BWH Graeme S. Steele , M.D., Urology, BWH Patrick Y. Wen , M.D., Neurology/Neuro-Oncology, BWH/DFCI Von Hippel-Lindau disease (VHL) is characterized by hemangioblastomas of the brain, spinal cord, and retina; renal cysts and renal cell carcinoma; pheochromocytoma; and endolymphatic sac tumors. The von Hippel-Lindau (VHL) Program at Brigham and Women's Hospital and Dana Farber Cancer Institute is a unique multidisciplinary clinic dedicated to treatment of von Hippel-Lindau patients.          Please direct inquiries to (617) 732-6826 for Nancy Olsen Bailey, M.B.A., R.N., and Donna Dello-Iacono, M.S.N., R.N. or call the clinic at (617)732-6810 to schedule an appointment.

34. Von Hippel-Lindau Disease The Essentials on von hippellindau disease Guidelines. Overview The Genome Project and von hippel-lindau disease. Specialized References http://www.icongrouponline.com/health/Von_Hippel-Lindau_Disease.html

ICON Health Publications Official Health Sourcebooks Search ICON Health Titles: The Official Patient's Sourcebook on VON HIPPEL-LINDAU DISEASE (Angioblastomatosis; Angiomatosis Retinae; Angiophakomatosis retinae et cerebelli; Cerebelloretinal hemangioblastomatosis; Cerebelloretinal hemangioblastomato-sis; Hippel Disease; Hippel-Lindau Syndrome; Lindau Disease; Retinocerebellar Angiomatosis) Revised and Updated for the Internet Age P A P E R B A C K Paperback Book Paperback Book Order by phone: 800-843-2665 (within USA) 1-201-272-3651 (from outside USA) Paperback Book Shipped in 3 to 5 business days E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Pages Price $28.95(USD) ISBN Published Synopsis A comprehensive manual for anyone interested in self-directed research on von Hippel-Lindau Disease. Fully referenced with ample Internet listings and glossary. Related Conditions/Synonyms Angioblastomatosis; Angiomatosis Retinae; Angiophakomatosis retinae et cerebelli; Cerebelloretinal hemangioblastomatosis; Cerebelloretinal hemangioblastomato-sis; Hippel Disease; Hippel-Lindau Syndrome; Lindau Disease; Retinocerebellar Angiomatosis Description Table of Contents Introduction Overview Organization Scope Moving Forward PART I: THE ESSENTIALS Chapter 1. The Essentials on Von Hippel-Lindau Disease: Guidelines

35. Von Hippel-Lindau Disease von hippellindau disease is a rare, genetic multi-system disorder characterized by the abnormal growth of blood vessels in certain parts of the body. http://healthlink.mcw.edu/article/921991275.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Von Hippel-Lindau Disease von Hippel-Lindau disease (VHL) is a rare, genetic multi-system disorder characterized by the abnormal growth of blood vessels in certain parts of the body (angiomatosis). The blood vessels "knot" together to form benign (non-cancerous) growths called angiomas. Angiomas may develop in the brain, the retina of the eyes, and other areas of the nervous system. Other types of tumors develop in the adrenal glands, the kidneys, or the pancreas. Symptoms of VHL vary among patients and depend on the size and location of the anigomas. Symptoms may include headaches, problems with balance and walking, dizziness, weakness of the limbs, vision problems, and high blood pressure. Cysts (fluid-filled sacs) and/or tumors (benign or cancerous) may develop around the angiomas and cause the symptoms listed above. Individuals with VHL are also at a higher risk than normal for certain types of cancer, especially kidney cancer. Treatment for VHL varies according to the location and size of the angiomas. In general, the objective of treatment is to treat the growths when they are small so that they do not cause permanent problems by putting pressure on the brain or spine, blocking the flow of cerebrospinal fluid in the nervous system, or impairing vision. Treatment of most cases of VHL usually involves surgery to remove the tumors before they become harmful. Individuals with VHL need careful monitoring by a physician and/or medical team familiar with the disorder.

36. Von Hippel-Lindau Disease Germline mutations in the von hippellindau disease (VHL) gene in Japanese VHL. Suprasellar hemangioblastoma in a patient with von hippel-lindau disease http://www.thedoctorsdoctor.com/diseases/vonhippel-lindau_disease.htm

Background This rare disease is autosomal dominantly inherited and contains a spectrum of clinical signs and symptoms. There are multiple clear cell neoplasms in various organs including retinal and central nervous system hemangioblastomas, renal cell carcinomas, pheochromocytomas, pancreatic endocrine tumors, and cysts. OUTLINE Epidemiology Disease Associations Pathogenesis Laboratory/Radiologic/Other Diagnostic Testing ... Internet Links DISEASE ASSOCIATIONS CHARACTERIZATION Von Hippel–Lindau disease: affecting 43 members of a single kindred. Lamiell JM, Salazar FG, Hsia YE. Medicine 1989;68:1–29. At least 25 distinct lesions have been described in this disorder In a review of 511 previously published cases in the literature, the incidence of the most common lesions are as follows: Retinal angiomatosis (57%) Cerebellar (55%), medullary (6%), and spinal (14%) hemangioblastomas; Pheochromocytoma (19%) Renal cysts (14%) R- enal cell carcinoma (24%) Epididymal cystadenoma (17%) Pancreatic cysts (14%) Pancreatic malignancy (4%) Molecular Characterization and Ophthalmic Investigation of a Large Family With Type 2A von Hippel-Lindau Disease.

37. American Family Physician: Recognition And Management Of Von Hippel-Lindau Disea Early diagnosis of von hippellindau disease is critical because of the prognostic 3 Patients with von hippel-lindau disease are predisposed to the http://www.findarticles.com/p/articles/mi_m3225/is_n6_v50/ai_15863858

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles American Family Physician Nov 1, 1994 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Related Searches Familial diseases / Diagnosis Brain tumors / Diagnosis Angiomatosis / Diagnosis Epidermal cyst / Diagnosis ... Von Hippel-Lindau disease / Diagnosis Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Recognition and management of von Hippel-Lindau disease American Family Physician Nov 1, 1994 by Emil P. Lesho Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. Early diagnosis of von Hippel-Lindau disease is critical because of the prognostic implications for both patients and their families. Unless the diagnosis is considered, the physician may incorrectly assume that the patient has an isolated lesion. Illustrative Case Definition and Diagnosis Von Hippel-Lindau disease is a rare phakomatosis that in the majority of cases is inherited in an autosomal dominant fashion, with penetrance approaching 100 percent.[1-4] The incidence of von Hippel-Lindau disease is difficult to determine because of varying definitions of what constitutes the disease, underreporting and underdiagnosis. The gene frequency is approximately one person per 100,000 population.[3] Patients with von Hippel-Lindau disease are predisposed to the development of hemangioblastomas of the cerebellum, retina and spinal cord; renal, pancreatic and epididymal cysts; renal carcinoma, and pheochromocytoma.[1-4]

38. Indian Journal Of Cancer: Pancreatic Involvement In Von Hippel-Lindau Disease.(O Access the article, Pancreatic involvement in von hippellindau disease.(Original Article) from Indian Journal of Cancer, a publication in the field of http://www.findarticles.com/p/articles/mi_hb3309/is_200410/ai_n13066739

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Indian Journal of Cancer October 2004 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Save a personal copy of any page on the Web and quickly find it again with Furl.net. It's free. Get started now. Pancreatic involvement in Von Hippel-Lindau disease.(Original Article) Indian Journal of Cancer October, 2004 by Bilge, Turgay Content provided in partnership with Read the full article with a Free Trial of HighBeam Research Byline: Mustafa. Eras, Mustafa. Yenigun, Cengiz. Acar, Baki. Kumbasar, Fuat. Sar, Turgay. Bilge BACKGROUND: Involvement of the pancreas in Von Hippel-Lindau disease that is a tumor predisposing syndrome mentioned in literature with some morbid and mortal progression. AIMS: For evaluation the faith of the pancreatic involvemet in VHL disease we analysed our patient population with VHL disease. MATERIALS AND METHODS: 12 of the 56 patients that were evaluated in our institute with the diagnosis of Von Hippel-Lindau disease had pancreatic involvement. They are periodically ...

39. Center For Cancer Risk Analysis: Von Hippel-Lindau Syndrome Cancer Genetics Prog The von hippellindau disease-Renal Cancer Program provides the latest about genetic counseling for von hippel-lindau disease and hereditary renal http://www.massgeneral.org/cancer/care/adult/risk/von_hippel.asp

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40. Von Hippel-Lindau Disease von hippellindau disease (VHL) is a rare, genetic multi-system disorder characterized by the abnormal growth of tumors in certain parts of the body http://www.clevelandclinic.org/health/health-info/docs/1300/1360.asp?index=6118&

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