1. Valley Fever Vaccine Project Of The Americas The disease is explained and lists information on the project to develop a vaccine. Includes extensive information about the disease. http://www.valleyfever.com/

Project Links Other related sites Valley Fever Primer An in depth look that answers most of your questions Project Update Slide Presentation - from Project Director Richard Hector, July 2004 Latest Newsletter One Page Flyer One Page Flyer (Español) “THE PIN PLAN” A “WE FIGHT THE FEVER” pin designed by Griffin Communications in Bakersfield is available for a minimum donation of $20. Businesses making a donation may be provided with pins for their employees attached to a card describing the donation that has been made. This idea originated with the Valley Fever Vaccine Project of the Americas, a Rotary District 5240 Project, but is a community wide, grassroots campaign. A very promising vaccine has been identified, but it must be proven in primates, manufacturing methods must be developed and it must be tested for safety in humans before human trials can begin. If 156,000 people give the minimum donation, we will be able to raise more than the $2,500,000 required for activities planned through 2004/2005.

2. Valley Fever Facts Factsheet with cause, symptoms, risk factors, diagnosis, complications, treatment, and prevention. http://www.astdhpphe.org/infect/valley.html

Valley Fever Valley fever is an emerging and sometimes deadly fungus infection. The valley fever fungus lives in soil and is spread through the air. Farmers, construction workers, and others who engage in activities that disturb the soil are at highest risk for valley fever. People with weak immune systems and persons of certain racial groups can become seriously ill from the infection. Valley fever is treatable with fungus-killing medicines. Persons at risk for valley fever should avoid exposure to dust and dry soil in areas where valley fever is common. What is valley fever? Valley fever is another name for the sometimes deadly infection coccidioidomycosis. It is called valley fever because the organism that causes it is commonly found in the soil of the southwestern United States, Mexico, and parts of Central and South America. Valley fever usually affects the lungs. When it affects other parts of the body, it is called disseminated valley fever. What is the infectious agent that causes valley fever? Valley fever is caused by Coccidioides immitis

3. Rift Valley Fever - A Disease That Can Spread With The Wind A mosquitoborne virual disease leading to serious economic losses in livestock, particularly sheep. Transmission, symptoms, related links. http://www.fao.org/NEWS/1998/rvf-e.htm

Rift Valley fever - a disease that can spread with the wind Rift Valley fever (RVF) - one of the priority diseases identified for attention by FAO's Emergency Prevention System ( EMPRES ) - is a mosquito-borne virus disease affecting ruminant animals and humans. It can cause very serious economic losses in livestock, particularly sheep. Goats, cattle, camels, Asian water buffaloes and possibly some wild antelopes are also susceptible. RVF was first described in the Rift Valley of Kenya in the early 1930s but it is now endemic in restricted sites throughout much of sub-Saharan Africa. Epidemics of the disease typically occur in cycles of five to 20 years. Recent major outbreaks hit Egypt in the late 1970s and Senegal and Mauritania in 1987. Because mosquitoes are easily carried long distances by wind, RVF has the potential to spread rapidly to new countries and even to new continents. The first sign of an epidemic of RVF is normally numerous abortions by pregnant sheep. An exceptionally high mortality rate in new-born sheep and goats is typical, with 90 percent of lambs and kids dying after showing little more than fever, lack of appetite and weakness. In older animals, the illness can also cause vomiting, blood-stained discharge from the nose, diarrhoea and jaundice. Older animals and cattle generally recover.

4. Tenacious Valley Fever Runs Gamut From Mild To Deadly Cases Explore how persons are touched by this disease. Visitors return home from the southwest and physicians are challenged to diagnose this disease. http://www.azcentral.com/health/wellness/articles/0830valleyfever31.html

OAS_listpos="Top1,Top2,Left3,x69,Bottom2,x70,x01,x02,x03,x04,x05,x06,Right3,Bottom1,BoxAd" var ScriptsLoaded = true; Fight breast cancer: Sign up for Buddy Check 12 e-mail alerts Traffic Weather News ... Subscribe to The Republic Tenacious valley fever runs gamut from mild to deadly cases Connie Midey The Arizona Republic Aug. 31, 2004 12:00 AM Monsoon storms always lured Danyelle Glenn outdoors, book and blanket in hand. Who could resist that daydreamy summertime gift, the chance - rare for a teen living in Tempe - to watch dust storms or sheets of rain, read a paragraph or two, then watch again, while snuggled in a lawn chair on the patio, feet planted against a wall? Not Danyelle. Not then. advertisement OAS_AD('BoxAd') Today, the 22-year-old Arizona State University student dreads monsoon season. She'll never know with certainty whether it was a monsoon dust storm that carried valley fever-causing fungal spores into her lungs and almost killed her. But four years after contracting the infectious disease, her pleasure in stormy days is gone. "I'm just paranoid now," Glenn says. "When I'm around kids who want to go outdoors during a storm, I tease them, 'Go out there and play in that valley fever if you want to get sick.' I'm like a doctor now."

5. Rift Valley Fever Facts Rift valley fever. Rift valley fever is a fevercausing viral disease that affects livestock and humans in Africa. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. Rift Valley Fever Facts Rift valley fever is a fevercausing viral disease that affects livestock and People get Rift valley fever mainly from the bite of an infected mosquito. http://www.astdhpphe.org/infect/rift.html

Rift Valley Fever Rift Valley fever is a fever-causing viral disease that affects livestock and humans in Africa. It is most common during years of heavy rainfall. People get Rift Valley fever mainly from the bite of an infected mosquito. The disease can also be spread by contact with the blood or body fluids of an infected animal. Rift Valley fever can cause serious eye infection, inflammation of the brain, severe bleeding (hemorrhage), and death. To prevent Rift Valley fever, travelers to Africa should take precautions against insect bites: 1) use insect repellent, 2) wear long sleeves and pants, and 3) use bednets. Travelers should also avoid contact with livestock in areas where outbreaks of Rift Valley fever are occurring. What is Rift Valley fever? Rift valley fever is a fever-causing disease that affects livestock (including cattle, buffalo, sheep, and goats) and humans in Africa. It is named after a trough stretching 4,000 miles from Jordan through eastern Africa to Mozambique. Rift Valley fever is spread mainly by infected mosquitoes and appears most often during years of heavy rainfall. Where is Rift Valley fever found?

7. Valley Fever Facts valley fever. valley fever is an emerging and sometimes deadly fungus infection. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Rift Valley Fever In Mauritania EMC disease outbreak news from 1998 http://www.who.int/emc/outbreak_news/n1998/nov/n10nov1998.html

9. Valley Fever Vaccine Project Of The Americas valley fever, coccidioidomycosis, is a lung disease that can cause mild flulike symptoms or it can be fatal. The disease is explained and lists http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. Valley Fever Vaccine Project Of The Americas The technical name for valley fever is Coccidioidomycosis, valley fever is a sickness of degree. About 60 percent of the people who breathe the spores http://www.valleyfever.com/whatis.htm

V alley Fever has long plagued - and mystified - man. Although it has been studied for the past 100 years, it is a disease that has remained impossible to control and difficult to treat. T he development of a vaccine is considered the only way to prevent this disease that costs so much...not only in terms of dollars, but also in human suffering. T his disease is serious, and can be fatal. It exacts a tremendous toll in personal and community resources. Valley Fever can't be eliminated, like smallpox and polio, but it can be controlled. We believe we have the basic knowledge, tools and people to develop a vaccine. Hans Einstein, M.D., F.A.C.P., F.C.C.P. Professor of Clinical Medicine U.S.C. School of Medicine Medical Director, Bakersfield Memorial Hospital T he technical name for Valley Fever is Coccidioidomycosis, or "Cocci" for short. It is caused by Coddidioides immitis , a fungus somewhat like yeast or mildew which lives in the soil. The tiny seeds, or spores, become wind-borne and are inhaled into the lungs, where the infection starts. Valley Fever is not contagious from person to person. It appears that after one exposure, the body develops immunity. Valley Fever is a sickness of degree. About 60 percent of the people who breathe the spores do not get sick at all. For some, it may feel like a cold or flu. For those sick enough to go to the doctor, it can be serious, with pneumonia-like symtoms, requiring medication and bed rest.

11. CNN.com - Rift Valley Fever Kills 6 More In Saudi Arabia; Death Toll Now 52 - Oc CNN http://www.cnn.com/2000/WORLD/meast/10/02/saudi.virus.ap/index.html

world middle east Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Rift Valley fever kills 6 more in Saudi Arabia; death toll now 52

12. Coccidioidomycosis Fact Sheet Environmental Epidemiology. Utah Public Health Lab Coccidioidomycosis(valley fever) (*PDF version) for printing. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Valley Fever Center For Excellence The VFCE staff presents programs on valley fever and risk management to medical The VFCE has also developed a valley fever Syllabus for Medical http://www.vfce.arizona.edu/

Southern Arizona VA Healthcare System University of Arizona Campaign Arizona The University of Arizona Foundation ... What's New at the VFCE Valley Fever is primarily a disease of the lungs that is common in the southwestern United States and northwestern Mexico. It is caused by the fungus Coccidioides sp. , which grows in soils in areas of low rainfall, high summer temperatures, and moderate winter temperatures. These fungal spores become airborne when the soil is disturbed by winds, construction, farming and other activities. In susceptible people and animals, infection occurs when a spore is inhaled. Within the lung, the spore changes into a larger, multicellular structure called a spherule. The spherule grows and bursts, releasing endospores which develop into spherules. Valley Fever symptoms generally occur within three weeks of exposure. Valley Fever is not a "contagious" disease, meaning it is not passed from person to person. Second infections are rare. Valley Fever can be a serious illness. It is estimated that there are about 100,000 cases in the southwestern U.S. each year, most of which resolve on their own. In patients with serious complications from the disease and those with immunosuppression (including AIDS and organ transplants), diagnosis and treatment is often complicated and expensive, and current therapy is sometimes inadequate to cure patients. Additionally, many visitors from regions where Valley Fever is not endemic develop Valley Fever after returning home from the Southwest, and their physicians may not be familiar with the disease.

14. Valley Fever - The Cure There is a cure for valley fever my dad discovered it 50 years ago! http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. Valley Fever valley fever is primarily a disease of the lungs that is common in the valley fever symptoms generally occur within three weeks of exposure. http://www.vfce.arizona.edu/ValleyFever/valley_fever.htm

Southern Arizona VA Healthcare System University of Arizona Campaign Arizona The University of Arizona Foundation ... Arizona Health Sciences Center What is Valley Fever? Valley Fever is primarily a disease of the lungs that is common in the southwestern United States and northwestern Mexico. It is caused by the fungus Coccidioides immitis , which grows in soils in areas of low rainfall, high summer temperatures, and moderate winter temperatures. These fungal spores become airborne when the soil is disturbed by winds, construction, farming and other activities. In susceptible people and animals, infection occurs when a spore is inhaled. Within the lung, the spore changes into a larger, multicellular structure called a spherule. The spherule grows and bursts, releasing endospores which develop into spherules. Valley Fever symptoms generally occur within three weeks of exposure. Valley Fever is not a "contagious" disease, meaning it is not passed from person to person. Second infections are rare. DIAGRAM OF LIFE CYCLE Spherule form (top half) multiplies in the lungs; mycelia (bottom half) grow in the soil

16. Rift Valley Fever CDC Special Pathogens Branch Outbreak Postings Glossary Rift valley fever View PDF (34KB) What is Rift valley fever? RVF virus electron micrograph. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Rift Valley Fever | CDC Special Pathogens Branch Rift valley fever (RVF) is an acute, fevercausing viral disease that These cases represent the first Rift valley fever cases identified outside Africa. http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/rvf.htm

Mission Statement Disease / Virus Information Arenaviruses Crimean-Congo Hemorrhagic Fever ... Glossary Rift Valley Fever View PDF What is Rift Valley fever? RVF virus electron micrograph. Image courtesy, C. S. Goldsmith, M. D. Bowen and T. G. Ksiazek Rift Valley fever (RVF) is an acute, fever-causing viral disease that affects domestic animals (such as cattle, buffalo, sheep, goats, and camels) and humans. RVF is most commonly associated with mosquito-borne epidemics during years of unusually heavy rainfall. The disease is caused by the RVF virus, a member of the genus Phlebovirus in the family Bunyaviridae. The disease was first reported among livestock by veterinary officers in Kenya in the early 1900s. Where is the disease found? Go to map showing RVF distribution RVF is generally found in regions of eastern and southern Africa where sheep and cattle are raised, but the virus also exists in most countries of sub-Saharan Africa and in Madagascar. In September 2000, a RVF outbreak was reported in Saudi Arabia and subsequently Yemen. These cases represent the first Rift Valley fever cases identified outside Africa. RVF virus primarily affects livestock and can cause disease in a large number of domestic animals (this situation is referred to as an "epizootic"). The presence of an RVF epizootic can lead to an epidemic among humans who are exposed to diseased animals. The most notable epizootic of RVF, which occurred in Kenya in 1950-1951, resulted in the death of an estimated 100,000 sheep. In 1977, the virus was detected in Egypt (probably exported there in infected domestic animals from Sudan) and caused a large outbreak of RVF among animals and humans. The first epidemic of RVF in West Africa was reported in 1987 and was linked to construction of the Senegal River Project. The project caused flooding in the lower Senegal River area and altered interactions between animals and humans resulting in transmission of the RVF virus to humans.

18. Lassa Fever CDC Special Pathogens Branch Hendra Virus Disease Lassa Fever Lymphocytic Choriomeningitis Marburg Hemorrhagic Fever Nipah Virus Encephalitis Rift valley fever http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. CNN.com - Health - International Experts Fight Rift Valley Fever In Saudi Arabia CNN http://www.cnn.com/2000/HEALTH/09/25/rift.fever.reut/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: International experts fight Rift Valley fever in Saudi Arabia, Yemen DUBAI, United Arab Emirates (Reuters) International health experts flew into Yemen and Saudi Arabia to help fight an outbreak of Rift Valley Fever that has killed dozens of people and devastated livestock herds. The official death toll in the two countries rose to 55, but the U.N.'s food body said on Monday it had reports of at least 74 deaths while local newspapers and medical sources say more than 200 have died since the virus struck over two weeks ago.

20. CTV.ca U.S. On Alert For Mosquito-borne Rift Valley Fever U.S. on alert for mosquitoborne Rift valley fever. Associated Press http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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