81. Tuberous Sclerosis Complex (Bourneville Disease) A 26year-old woman with tuberous sclerosis complex had numerous cutaneous tuberous sclerosis is a hamartomatous disease with defects in either hamartin http://dermatology.cdlib.org/103/NYU/case_presentations/042004n8.html

DOJ Contents Tuberous sclerosis complex (Bourneville disease) Christopher T Cassetty MD Dermatology Online Journal 10 (3): 17 From the Ronald O. Perelman Department of Dermatology, New York University Abstract A 26-year-old woman with tuberous sclerosis complex had numerous cutaneous manifestations and systemic manifestations that included subependymal nodules, pulmonary lymphangioleiomyomatosis, renal cysts, and bilateral renal angiomyolipomas. Tuberous sclerosis is a hamartomatous disease with defects in either hamartin (TSC1) or tuberin (TSC2) that can be of autosomal dominant inheritance or spontaneous mutation. Clinical synopsis History. The patient receives depo-medroxyprogesterone acetate injections for uterine fibroids, omeprazole for gastro-esophageal reflux disease, and ipratropium bromide and albuterol sulfate inhalation aerosol for shortness of breath. She denies ocular or cardiac involvement. There is no family history of similar signs or symptoms. Figure 1 Figure 2 Figure 3 Physical examination.

82. Tuberous Sclerosis Medical Information tuberous sclerosis Information from Drugs.com. tuberous sclerosis is a group of two genetic disorders characterized by problems with the skin, http://www.drugs.com/enc/tuberous_sclerosis.html

Home New Drugs Latest News Drug Interactions ... Forum Drugs.com - prescription drug and medicine information available on over 24,000 approved- medications and pharmaceuticals, including side effects and drug interactions. Log-in Register Advertisement Buy a Link Now Special Offers From our sponsors Categories Diabetes Gastro Center Weight Loss AIDS/HIV ... Sexual Health Advertisement Advanced Search Or click the first letter of a drug name: A B C D ... Z Tuberous sclerosis Injury Disease Nutrition Poison ... Tuberous sclerosis, hypopigmented macule Tuberous sclerosis Definition Tuberous sclerosis is a group of two genetic disorders characterized by problems with the skin, brain/nervous system, and kidneys, and a predisposition to tumors. The diseases are named after a characteristic abnormal growth in the brain, which takes the shape of a tuber or root. Alternative Names Adenoma sebaceum Causes Tuberous sclerosis is inherited as an autosomal dominant trait (only one parent must pass on the bad gene for the child to get the disease). However, a high percentage of cases are due to new mutations (which occur in the sperm or egg of one of the parents), so there usually is no family history of the disease. It is one of a group of diseases described as neuro-cutaneous syndromes because of extensive involvement of both the skin and the central nervous system (brain and/or spinal cord).

83. ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies: Recruiting, Study of Skin Tumors in tuberous sclerosis Conditions Hereditary Neoplastic Syndrome; tuberous sclerosis http://www.clinicaltrials.gov/ct/gui/action/SearchAction?term=Tuberous Sclerosis

84. Clinical Trial: Study Of Skin Tumors In Tuberous Sclerosis tuberous sclerosis is a rare, hereditary disease in which patients develop Patients with tuberous sclerosis develop benign cutaneous tumors that are http://www.clinicaltrials.gov/ct/show/NCT00001975

Home Search Browse Resources ... About Study of Skin Tumors in Tuberous Sclerosis This study is currently recruiting patients. Verified by National Institutes of Health Clinical Center (CC) December 13, 2004 Sponsored by: National Heart, Lung, and Blood Institute (NHLBI) Information provided by: National Institutes of Health Clinical Center (CC) ClinicalTrials.gov Identifier: Purpose Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can affect various organs, including the heart, lungs, kidneys, skin, and central nervous system, with serious medical consequences. The severity of disease varies greatly among patients, from barely detectable to fatal. This study will investigate what causes skin tumors to develop in patients with this disease. Patients with tuberous sclerosis 18 years and older may enroll in this study. Participants will undergo a medical history and thorough skin examination by a dermatologist. Those with skin tumors will be asked to undergo biopsy (tissue removal) of up to four lesions, under a local anesthetic, for research purposes. The biopsies will all be done the same day. The tissue samples will be used for: examination of genetic changes, measurement of certain proteins and other substances, and growing in culture to study the genetics of tuberous sclerosis. Condition Hereditary Neoplastic Syndrome Tuberous Sclerosis MedlinePlus related topics: Cancer Cancer Alternative Therapies Genetic Disorders Tuberous Sclerosis ... Genetics Home Reference related topics:

85. Tuberous Sclerosis NeuroLearn NeuroHelp Malformations @ Background Summary tuberous sclerosis is a systemic disease with the brain as the most Diagnostic criteria tuberous sclerosis has been divided into definitive, http://moon.ouhsc.edu/kfung/JTY1/NeuroHelp/ZNG0IE05.htm

Tuberous Sclerosis NeuroLearn NeuroHelp Malformations Background ... Reference BACKGROUND AND CLINICAL INFORMATION Head Summary: tuberous sclerosis is a systemic disease with the brain as the most frequently affected organ. Clinically it is characterized by seizures mental retardation and adenoma sebaceum . Pathologically, there is cortical tuber subependymal nodules , and heterotopia in white matter of the brain. Subependymal giant cell astrocytoma (SEGA) is almost always associated with tuberous sclerosis. Review article- Webb and Osborne Pathogenesis: the bizarre cells in the subependymal nodules may be pleuripotential and may represent a disruption of both migration and differentiation. Clinical features: Diagnostic criteria: Tuberous sclerosis has been divided into definitive, provisional or suspicious category by clinical criteria Roa c h ES et al., 1998 Gomez MR, 1991 Clinical triad: seizures, mental retardation and adenoma sebaceum (facial angiofibroma). Only about 1/3 of the patients express the entire triad. The patients may also have behavioural problems such as hyperactivity. Seizures usually manifest in the first few months of life but adenoma sebacum will not appear until about 2 years of age and this will make the diagnosis difficult.

86. Overview, Cincinnati Children's Hospital Medical Center The tuberous sclerosis Clinic at Childrens Hospital Medical Center of Cincinnati assists in the medical care of children/adults with tuberous sclerosis. http://www.cincinnatichildrens.org/svc/alpha/t/tuberous-sclerosis/

Home Contact Us Site Map Go to Advanced Search ... Tuberous Sclerosis Program Overview Patient Referrals Patient Expectations Contact Us Tuberous Sclerosis Program Overview The Tuberous Sclerosis Clinic at Cincinnati Children's Hospital Medical Center, the largest in the United States, was organized in 1993 to assist in the medical care of children and adults who have or are suspected of having Tuberous Sclerosis. The purpose of the Tuberous Sclerosis clinic is not to replace care from the child's pediatrician or family physician, but to assist the primary care doctor in dealing with those aspects of Tuberous Sclerosis that affect the child's health or development. The basis of the Tuberous Sclerosis Clinic is the realization that people with Tuberous Sclerosis are different from other individuals who have epilepsy, learning disabilities, behavior problems, etc. For too long the unique problems found in this disease have been lumped together with similar disorders in children without tuberous sclerosis. Yet, research has increasingly shown that disorders of the brain, learning, heart, kidney and other organs in Tuberous Sclerosis are different than the same conditions in individuals without Tuberous Sclerosis. The Tuberous Sclerosis Clinic is managed by the Neurology Department at Cincinnati Children's, and is part of the University of Cincinnati Medical Center.

87. Understanding And Treating Tuberous Sclerosis Complex Understanding and Treating tuberous sclerosis Complex and the tuberous sclerosis Alliance invite research grant applications aimed at understanding or http://www.fedgrants.gov/Applicants/HHS/NIH/NIH/PAS-05-085/Grant.html

Understanding and Treating Tuberous Sclerosis Complex General Information Document Type: Grants Notice Funding Opportunity Number: PAS-05-085 Posted Date: Apr 12, 2005 Original Due Date for Applications: Multiple Receipt Dates - See Link to Full Announcement for details. Current Due Date for Applications: Multiple Receipt Dates - See Link to Full Announcement for details. Archive Date: Apr 01, 2008 Funding Instrument Type: Grant Category of Funding Activity: Education Health Expected Number of Awards: Not Available. Estimated Total Program Funding: Award Ceiling: none Award Floor: none CFDA Number: 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.849 Kidney Diseases, Urology and Hematology Research 93.242 Mental Health Research Grants 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.396 Cancer Biology Research Cost Sharing or Matching Requirement: No Eligible Applicants Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

88. Understanding And Treating Tuberous Sclerosis Complex Fund number PAS05-085 Title Understanding and Treating tuberous sclerosis Complex. Grant - Posted on Apr 12, 2005 http://www.fedgrants.gov/Applicants/HHS/NIH/NIH/PAS-05-085/listing.html

Department of Health and Human Services Grant Opportunities Office : National Institutes of Health Location : National Institutes of Health Fund number : PAS-05-085 Title : Understanding and Treating Tuberous Sclerosis Complex Grant - Posted on Apr 12, 2005 SEARCH for Grants

89. National Tuberous Sclerosis Association Home Page National tuberous sclerosis Association Home Page httphttp//www.ntsa.org/ Welcome to the NTSA WWWeb Home Page! We re very proud to welcome you to our web http://www.pslgroup.com/dg/1fefe.htm

90. Tuberous Sclerosis Definition - Medical Dictionary Definitions Of Popular Medica Online Medical Dictionary and glossary with medical definitions. http://www.medterms.com/script/main/art.asp?articlekey=11454

91. Tuberous Sclerosis The tuberous sclerosis Association (TSA) was formed in 1977 to offer There is also information about tuberous sclerosis which is updated regularly. http://omni.ac.uk/browse/mesh/D014402.html

low graphics Tuberous Sclerosis other: Canavan Disease Cockayne Syndrome Hepatolenticular Degeneration Hereditary Central Nervous System Demyelinating Diseases ... Tuberous Sclerosis Association (TSA) The Tuberous Sclerosis Association (TSA) was formed in 1977 to offer support to patients and families.The site provides general information about the charity, including activities, fundraising, research projects and publications. There is also information about Tuberous Sclerosis which is updated regularly. Tuberous Sclerosis Great Britain Charities Last modified: 09 Sep 2005

92. Tuberous Sclerosis. DermNet NZ Authoritative facts about the skin from the New Zealand Dermatological Society. http://dermnetnz.org/systemic/tuberous-sclerosis.html

@import url("/common/screen.css"); DermNet NZ Ad Authoritative facts about the skin from the New Zealand Dermatological Society Incorporated Home For patients For doctors ... Site map Search: Home Systemic Tuberous sclerosis What is tuberous sclerosis? Tuberous sclerosis (TS) or tuberous sclerosis complex (TSC) is a genetic disorder that is characterised by hamartomas in many organs, but particularly the skin, brain, eye, kidney and heart. Hamartomas are non-cancerous malformations composed of overgrowth of the cells and tissues that normally occur in the affected area and include naevi (birthmarks). Skin lesions, epileptic seizures and developmental delay/behavioural problems are the main features of TSC. However, individuals with the condition may be affected in many different ways and with differing degrees of severity. Some patients may have very few or no symptoms at all, whilst others may be severely affected with a multitude of symptoms. What causes TS and who gets it? Tuberous sclerosis is a genetic disorder. About one third of all cases of TS are inherited from an affected parent. All other cases are due to sporadic new mutations of the tuberin protein gene occurring in the early stages of life. People of all races and sex may be affected. The condition may become apparent any time from infancy to adulthood but usually occurs between 2-6 years of age.

93. TheFetus.net - Tuberous Sclerosis -Philippe Jeanty, MD, PhD & Sandra R Silva, MD Comprehensive guide to prenatal ultrasound. Covers all aspects of sonography in pregnancy and the fetus. http://www.thefetus.net/page.php?id=445

94. Dr. Goldberg Tucson Dermatology LASER Expert Show Me More Info on tuberous sclerosis. All photos are unretouched and are patients Before tuberous sclerosis. After Co2 and Pulsed Dye Lasers http://www.pimaderm.com/tuberous_sclerosis_photo_1.shtml?3

95. Ae tuberous sclerosis. Findings Axial CT images show chunky calcifications at the graywhite junction, without edema or mass effect. http://www.med.uc.edu/neurorad/webpage/esa.html

Click on small image to see full size. Tuberous Sclerosis Findings: Axial CT images show chunky calcifications at the gray-white junction, without edema or mass effect. Multiple MR images show enhancement in the region of the right Foramen of Monro, with scattered areas of subcortical T2 signal abnormality. Discussion: The constellation of findings is highly consistent with a diagnosis of tuberous sclerosis. Clinically these patients present with the triad of seizures (90%), mental retardation (50%), and adenoma sebaceum (90%). -autosomal dominant, 1/10,000-1/50,000 -chromosomes: TSC 1 9q, TSC 2 16p- forme fruste 5x more common -criteria (need 1) -facial angiofibromas -ungual fibroma (17%) -retinal hamartoma -cortical tubers (50%) -subependymal nodules -multiple renal AML -presumptive (need 2) -hypomelanotic nodules -shagreen patch -single AML -multicystic kidney -cardiac rhabdomyoma (30-50%) -LAM pattern, honeycomb lung -first degree relative with TS -subependymal giant cell astrocytoma in 15% (WHO grade I) -other findings: retinal benign astrocytic hamartoma, heterotopias, myelination disorder, ventriculomegaly

96. DermAtlas: Online Dermatology Image Library Dermatology Image,tuberous Sclerosis tuberous sclerosisTalking to Your Child about tuberous sclerosis Complex tuberous sclerosis Association Warning Signs in tuberous sclerosis tuberous sclerosis Association http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=189

97. Search Result For "Tuberous Sclerosis" Adolescents with tuberous sclerosis Complex; Behaviour In tuberous sclerosis; Brain Imaging In tuberous sclerosis; Clinical Manifestions of TS; http://www.noah-health.org/search/results.php?lang=1&keyword=Tuberous Sclerosis&

98. Tuberous Sclerosis - The Knowledge Database Of The Swedish National Board Of Hea The term tuberous sclerosis refers to a tuberlike hardening of the cerebral cortex that Hence the current name of TSC or tuberous sclerosis complex. http://www.sos.se/smkh/2002-110-8/2002-110-8.htm

Socialstyrelsen 106 30 Stockholm The Board classifies its publications into different types of document. This is a Review of knowledge . This means that the report is based on science and/or tried and tested experience. Reviews of knowledge shall, among other things, support knowledge-based care and treatment, method development and other work for improvement; shall stimulate and facilitate quality assurance and effective use of resources and/or elucidate effects of distribution. The Board is responsible for contents and conclusions. Tuberous Sclerosis Tuberous sclerosis complex TSC Table of Contents The disease/injury/diagnosis Incidence Aetiology of the disease/injury Heredity ... Database references Document date: 2002-03-08 Version: 1.2 Article number: 2002-110-8 English index Search The aphabetical list This is an excerpt from the database of the Swedish National Board of Health and Welfare on rare diseases. The concept of "rare diseases" is defined as: "Disorders resulting in extensive disability whick affect no more than 100 individuals in one million inhabitants". The ambition underlying the database is to provide information to the public, including patients and their families, as well as to health professionals. The disease/injury/diagnosis The term "tuberous sclerosis" refers to a tuber-like hardening of the cerebral cortex that often characterizes this disorder. The first complete description of the disease was made by a French physician named Bourneville in 1880, and it is often also known as Bourneville's disease. The abnormalities may involve one or more organs, and may be more or less extensive. Hence the current name of TSC or tuberous sclerosis complex. In some cases the only indication of the disease may be barely visible skin abnormalities. This text primarily describes the forms of the disease that entail substantial disability, although there are many other variations. Mild cases of tuberous sclerosis do not necessarily involve any mental retardation or functional disability.

99. BrainTalk Communities - Tuberous Sclerosis Reload this Page tuberous sclerosis. User Name, Remember Me? Password Threads in Forum tuberous sclerosis, Forum Tools, Search this Forum. Announcement http://brain.hastypastry.net/forums/forumdisplay.php?f=261

100. UpToDate Tuberous Sclerosis INTRODUCTION — tuberous sclerosis (TS) is an inherited neurocutaneous GENETICS — tuberous sclerosis is an autosomal dominant genetic disorder with an http://patients.uptodate.com/topic.asp?file=ped_neur/18657&title=Kidney cancer

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 5     81-100 of 115    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20