121. Institute For Tuberculosis Research Dedicated to the discovery and development of new effective, lowcost, therapeutics for the treatment of tuberculosis. Includes description of research projects, facilities, and methods, and welcomes donations to sponsor drug discovery. http://itr.pharm.uic.edu

To discover and develop new effective, low-cost drugs for the treatment of tuberculosis Mycobacterium tuberculosis , the etiologic agent of tuberculosis (TB), is responsible for more deaths than any other single bacterial species. The disease must be treated with multiple drugs to prevent the selection of drug resistant strains . Drug-sensitive tuberculosis (TB) is usually curable in 6 months if all drugs are taken regularly, however pati ent non-compliance, incorrect prescribing and irregular drug supply can all contribute to treatment failure and the selection for drug-resistant strains . Multiple drug-resistant (MDR) tuberculosis has a much lower cure rate due to the lower efficacy and higher toxicity of the second-line drugs used in its treatment.

122. Diseases: Tuberculosis tuberculosis is one of the most prevalent infections of human beings and contributes considerably to illness and death around the world. http://hopkins-id.edu/diseases/tb/tb.html

Go to a Section in TB Table of Contents Treatment Prophylaxis References by Richard E. Chaisson, M.D. Tuberculosis is one of the most prevalent infections of human beings and contributes considerably to illness and death around the world. Globally, it is estimated that approximately one-third of the global population is infected with Mycobacterium tuberculosis and that seven to eight million new cases of tuberculosis occur each year. Annual tuberculosis mortality is between two and three million people, making this disease the most common infectious cause of death in the world. Most tuberculosis cases and deaths occur in developing countries, notably in Asia and Africa. In the United States, the annual incidence of tuberculosis is considerably lower than in developing countries. Nonetheless, tuberculosis remains an important problem in this country and the impact of tuberculosis has worsened in recent years. Epidemiology and Natural History Classification and Diagnosis Treatment Prophylaxis ... TB News Conference Archives: posted 5/13/99 posted 3/10/99 Top of page Next page Epidemiology and Natural History Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained in this site because no single reference or service can take the place of medical training, education, and experience. Consumers are cautioned that this site is not intended to provide medical advice about any specific medical condition they may have or treatment they may need and they are encouraged to call or see their physician or other health care provider promptly with any health related questions they may have.

123. Tuberculosis - EMedicine Health Consumer health resource center providing information on the causes, symptoms, and treatment of TB. http://www.emedicinehealth.com/articles/17621-1.asp

Search September 9, 2005 Registration Healthcare Professionals You are in: Bacterial and Viral Infections Tuberculosis Tuberculosis Overview Mycobacterium tuberculosis and Mycobacterium bovis Physicians in ancient Greece called this illness "phthisis" to reflect its wasting character. During the 17th and 18th centuries, TB caused up to 25% of all deaths in Europe. In more recent times, tuberculosis has been called "consumption." Robert Koch isolated the tubercle bacillus in 1882 and established TB as an infectious disease. In the 19th century, patients were isolated in sanatoria and given treatments such as injecting air into the chest cavity. Attempts were made to decrease lung size by surgery called thoracoplasty. During the first half of the 20th century, no effective treatment was available. Streptomycin, the first antibiotic to fight TB, was introduced in 1946, and isoniazid (Laniazid, Nydrazid) became available in 1952. M tuberculosis is a rod-shaped, slow-growing bacterium. M tuberculosis ' cell wall has high acid content, which makes it hydrophobic, resistant to oral fluids.

124. Microbiologist Seeks Employment Ph.D., M.S.P.H. Resume and CV. Experience includes all areas of microbiology to include virology (both serology and viral isolation), parasitology, mycology, tuberculosis, and clinical immunology. http://home.usaa.net/~rgwhiddon

ROBERT G. WHIDDON, PH.D., M.S.P.H. MICROBIOLOGY / PUBLIC HEALTH / QUALITY 5651 Shoal Creek Drive Haymarket, Virginia 20169 Email: rgwhiddon@earthlink.net Website: http://home.usaa.net/~rgwhiddon I have developed and applied skills in microbiology and infection control , supervised as many as 26 employees in large (500 bed hospitals) reference laboratories. My experience includes all areas of microbiology to include virology (both serology and viral isolation), parasitology mycology tuberculosis , and clinical immunology . I taught in active training programs in these centers for many specialties to include infectious disease pathology , and medical technology . I have been an invited lecturer at University of Texas Health Science Center in San Antonio, and I am a contributing author to the textbook used in that program. I have built complex relational databases in Access and Paradox for management of laboratory supply operations. I have designed a laboratory computer system featuring edit checks and conditional branching logic. I was a reviewer at the Center for Drug Evaluation and Research - Anti-Infectives at the Food and Drug Administration . I have written many computer applications that improved operations, and cut costs. I have used

125. Nat' Academies Press, Tuberculosis In The Workplace (2001) Appendix C The Occupational tuberculosis Risk of Health Care Workers, 189229 (skim). Appendix D Effects of CDC Guidelines on tuberculosis Control in Health http://www.nap.edu/openbook/0309073308/html/

Read more than 3,000 books online FREE! More than 900 PDFs now available for sale HOME ABOUT NAP CONTACT NAP HELP ... ORDERING INFO Items in cart [0] TRY OUR SPECIAL DISCOVERY ENGINE Questions? Call 888-624-8373 Tuberculosis in the Workplace (2001) Institute of Medicine ( IOM Find More Like This Book Research ... Dashboard NEW! BUY This Book CHAPTER SELECTOR: Openbook Linked Table of Contents Front Matter, pp. i-xvi Summary, pp. 1-12 1 Introduction, pp. 13-23 2 Basics of Tuberculosis, pp. 24-42 3 Occupational Safety and Health Regulation in Context, pp. 43-55 4 Comparison of CDC Guidelines and Proposed OSHA Rule, pp. 56-80 5 Occupational Risk of Tuberculosis, pp. 81-107 6 Implementation and Effects of CDC Guidelines, pp. 108-136 7 Regulation and the Future of Tuberculosis in the Workplace, pp. 137-156 References, pp. 157-172 Appendix A Study Origins and Activities, pp. 173-178 Appendix B The Tuberculin Skin Test, pp. 179-188 Appendix C The Occupational Tuberculosis Risk of Health Care..., pp. 189-229 Appendix D Effects of CDC Guidelines on Tuberculosis Control..., pp. 230-270

126. EMedicine - Cutaneous Tuberculosis : Article By Monte S Meltzer, MD Article by Monte S Meltzer, MD. http://www.emedicine.com/derm/topic434.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Mycobacterial Infections Cutaneous Tuberculosis Last Updated: November 5, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: tuberculous chancre, tuberculosis verrucosa cutis, miliary tuberculosis of the skin, scrofuloderma, tuberculous gumma, tuberculosis cutis orificialis, lupus vulgaris, erythema induratum, papulonecrotic tuberculid, lichen scrofulosorum, cutaneous TB AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Monte S Meltzer, MD , Chief, Dermatology Service, Union Memorial Hospital Coauthor(s): Carol A Nacy, PhD , Adjunct Professor, Department of Biology, Catholic University of America Monte S Meltzer, MD, is a member of the following medical societies: Alpha Omega Alpha , and American Academy of Dermatology Editor(s): Shyam Verma, MBBS, DVD, FAAD

127. Nat' Academies Press, Ending Neglect: The Elimination Of Tuberculosis In The Uni 3 tuberculosis Elimination and the Changing Role of tuberculosis Control Programs Appendix E Estimating the Number of tuberculosis Cases That Can Be http://www.nap.edu/openbook/0309070287/html/

Read more than 3,000 books online FREE! More than 900 PDFs now available for sale HOME ABOUT NAP CONTACT NAP HELP ... ORDERING INFO Items in cart [0] TRY OUR SPECIAL DISCOVERY ENGINE Questions? Call 888-624-8373 Ending Neglect: The Elimination of Tuberculosis in the United States (2000) Institute of Medicine ( IOM Find More Like This Book Research ... Dashboard NEW! BUY This Book CHAPTER SELECTOR: Openbook Linked Table of Contents Front Matter, pp. i-xviii Executive Summary, pp. 1-12 1 Fundamentals of Tuberculosis and Tuberculosis Control, pp. 13-22 2 The Current Situation and How We Got Here, pp. 23-50 3 Tuberculosis Elimination and the Changing Role of Tubercul..., pp. 51-85 4 Advancing Toward Elimination, pp. 86-121 5 Developing the Tools for Tuberculosis Elimination, pp. 122-148 6 The U.S. Role in Global Tuberculosis Control, pp. 149-158 7 Mobilizing for Elimination, pp. 159-168 Appendix A Statement of Task, pp. 169-172 Appendix B Public Session Agendas, pp. 173-181 Appendix C Site Visit Summaries, pp. 182-204 Appendix D Role of Public Health Laboratories in the Control..., pp. 205-233

128. Home Page A comprehensive information site for tuberculosis, a mycobacterial infectious disease, that is developed and maintained by local volunteers. Features area resources, clinics, a photo gallery, and contacts. http://www.tbchicago.org/

TB All Time Low in Chicago in 2001 Click on the dancing drug on bug icon to enter Web site for TB Chicago is hosted as a service to the public and is not an agency of any governmental organization Sponsors: Drs. Bapu P. and Vijaya L. Arekapudi Lake Shore Medical Associates, Ltd. Bapu P. Arekapudi, M.D

129. Mycobacterium Tuberculosis The Microbiology Video Library broadcast quality digital video, web videos and commissions. http://www-micro.msb.le.ac.uk/video/Mtuberculosis.html

Microbiology @ Leicester Microbiology Video Library Mycobacterium tuberculosis Search Mycobacterium tuberculosis "Captain among these Men of Death" (John Bunyon 1660) White Death White Plague Consumption Tuberculosis... Where did TB come from? Mycobacteria are Gram-positive (no outer cell membrane), non-motile , pleomorphic rods, related to the Actinomyces. Most Mycobacteria are found in habitats such as water or soil. However, a few are intracellular pathogens of animals and humans. Mycobacterium tuberculosis , along with M. bovis M. africanum , and M. microti all cause the disease known as tuberculosis (TB) and are members of the tuberculosis species complex. Each member of the TB complex is pathogenic, but M. tuberculosis is pathogenic for humans while M. bovis is usually pathogenic for animals. M. bovis was causing TB in the animal kingdom long before invading humans. However, after the domestication of cattle between 8000-4000 BC, there is archaeological evidence of human infection by M. bovis

130. THE MERCK MANUAL, Sec. 13, Ch. 157, Bacterial Diseases TB refers only to disease caused by Mycobacterium tuberculosis, M. bovis, or M. africanum. OTHER MYCOBACTERIAL INFECTIONS RESEMBLING tuberculosis http://www.merck.com/mrkshared/mmanual/section13/chapter157/157g.jsp

131. CNN.com - Scientists Discover Tuberculosis Strategy For Hiding In Body - August CNN http://www.cnn.com/2000/HEALTH/08/17/tuberculosis.trick.ap/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Scientists discover tuberculosis strategy for hiding in body (AP) Scientists have identified a key trick that tuberculosis bacteria use to lie low in the body for years before going on the attack a discovery that could open a whole new approach to fighting a disease that kills more than 2 million people around the world each year. "In terms of public health, there is a long way to go. This is an important step in the right direction," said Dr. William Bishai, professor of international health and medicine at Johns Hopkins University.

132. Tuberculosis tuberculosis has been known by many names.The Greeks called it phthisis (to waste). There had been much speculation as to the cause of tuberculosis, http://ist-socrates.berkeley.edu/~jmp/TB1.htm

Why is the tuberculosis bacterium so successful? History of Tuberculosis: Tuberculosis has been known by many names. The Greeks called it phthisis (to waste). In medieval times, it was called The King’s Evil because the newly crowned kings of England and France were thought to have powers to heal TB with their touch The White Plague refers to the TB epidemic in Europe during the 18 th century. To us, the most familiar historical term for TB is consumption , due to the consumption and wearing away of the body. There had been much speculation as to the cause of tuberculosis, but it was not until 1865 that a French military doctor, Jean-Antoine Villemin discovered that the disease was communicable between humans and cattle, and between cattle and rabbits. This led to the understanding that the disease is caused by a specific microorganism. In 1882, Robert Koch discovered a staining technique that allowed him to see the specific mycobacterium that is now known to cause tuberculosis. It was only then that the battle against the disease really begun. At the time of the discovery of the bacteria, 1 in 5 people developed TB in their lifetime.

133. Stanford Center For Tuberculosis Research is to foster international collaborations between tuberculosis researchers. what we do here at Stanford, and about tuberculosis research in general. http://www.stanford.edu/group/molepi/

The purpose of these pages is to foster international collaborations between tuberculosis researchers. We hope that our layout helps you learn more about what we do here at Stanford, and about tuberculosis research in general. There are links to home pages of personnel , including those of the Principle Investigator here, Dr. Peter Small. A summary of research and a list of publications for the Stanford Center for Tuberculosis Research are provided. Personnel Research Summary Bibliography Announcements ... Home Updated January, 2004

134. WHO Launches New Bid To Stop Tuberculosis CNN http://cnn.com/2001/HEALTH/conditions/03/21/un.tuberculosis.ap/index.html

135. Healthfinder® - Tuberculosis Carefully selected government and nonprofit health information on tuberculosis. http://www.healthfinder.gov/Scripts/SearchContext.asp?topic=877

136. Tuberculosis - Topix.net News on tuberculosis. http://rss.topix.net/rss/health/tuberculosis.xml

http://www.topix.net/health/tuberculosis News on Tuberculosis from Topix.net en-us feedback@topix.net feedback@topix.net http://www.topix.net/ http://www.topix.net/pics/topix-rss.gif http://topix.net/r/0gVqiiR0PAh3hI4tWSPZPcvNBU5bszStmTpe8GA932nOU=2Fpt6UlzXpeggKshliSYWYqjUYowa8=2Fhvu84P721oZ4zaiGKzRdFQ6jfbuUoNX96vFOTh8KE=2Fgk4c7sSRPCtwMEeGzxvvyRWaNFPnIxFZVA=3D=3D Clinicians at St George's Hospital in London report that patients are much more likely to experience efavirenz-related side-effects when 800mg efavirenz is co-administered with the anti-tuberculosis drug, ... Aidsmap.com Thu, 08 Sep 2005 00:22:20 GMT http://topix.net/r/0gVqiiR0PAh3hI4tWSPZPcvNBU5bszStmTpe8GA932nNLWaM2d8GcUO305BkxWgtEmaRcuaXPcK5XyvIncLA5yQK06279zz7tSUsaVNOoMR8hq2xkIlpP=2BLH=2BjdsbA78uEmVH3dkWb1MpUXwLY8Rtk7=2BHBx6K8iP101Fye9uv9OhKfOlEebJhJuKAwO9HfPBCkN2eTe4Y4zkPolT8KpVN6emWRRRxOw57PKOIXrnwsfTGOb0JTVYS=2F2fZFPpDTnJf A campaign to fight "I see this as a substantial step in the right direction but that funding gap... has got to be filled," Richard Feachem, the director of the Global Fund to Fight AIDS, Tuberculosis and ... Yahoo Wed, 07 Sep 2005 06:45:39 GMT

137. CNN.com - Health - Disney: No Risk To Visitors From Employee With TB - March 22, CNN http://cnn.com/2001/HEALTH/conditions/03/22/disney.tuberculosis.02/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe set your edition Languages Spanish Portuguese German Italian Danish Japanese Korean Arabic Time, Inc. Time.com People Fortune EW Disney: No risk to visitors from employee with TB ORLANDO, Florida (CNN) There is no health risk to visitors to Walt Disney World's Magic Kingdom, even though one employee a costumed character was diagnosed with active tuberculosis, a spokeswoman for the theme park said Thursday. "The health department has said there's no risk to our visitors," said Diane Ledder, a Disney spokeswoman. No tests of visitors are planned, she added. A spokeswoman at the Orange County Health Department confirmed that officials felt there is no health risk and no testing of visitors is warranted. A doctor at the Centers for Disease Control and Prevention in Atlanta said it is unlikely any visitors contracted the disease, noting the employee wore a character mask. Dr. Helene Gayle said transmission requires "prolonged contact" and said there is "no real cause for concern." However, she said, parents who are concerned can contact their pediatrician.

138. State Of Oregon: Tuberculosis Control Contact Us tuberculosis Control Fact Sheets Guidelines Rules Statutes Publications Epidemiology Oregon tuberculosis Control Prevention http://egov.oregon.gov/DHS/ph/tb/index.shtml

Text-Only Site State Directory Agencies A-Z Accessibility ... Related Sites Current Topics School Screening Rule Deleted Updated Investigative Guide Finalized 2004 Case Data New Tools for Local Programs Oregon HST Programs HST Section HIV Client Services HIV CAREAssist Oregon Local Health Departments Directory HIV Prevention STD Program Benefits of Public Health: Longer lives, Better health, Safer environments Text Only State Directory Agencies A-Z About Oregon.gov ... Web Site Feedback

139. Explore The Microscopic World Of Health Science tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis and Mycobacterium tuberculosis Thin section transmission electron micrograph of http://www.wadsworth.org/databank/mycotubr.htm

Navigate Wadsworth Center Disease Carriers document.write(mw_crumbs("","","Wadsworth Center")) Bacteria: Mycobacterium tuberculosis Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis and is annually responsible for nearly two million deaths worldwide. A third of the world's population is currently infected with the TB bacillus, and more than eight million new cases are diagnosed each year. TB has reemerged as a serious public health threat worldwide because of a significant increase in multiple-drug-resistant TB and synergism between Human Immunodeficiency Virus (HIV) and M. tuberculosis infection. TB is transmitted from person to person by the aerosol route, and treatment requires a six to 12 month regimen with at least two antibiotics. Failure to complete the full course of drug therapy can lead to M. tuberculosis organisms that are resistant to one or more anti-tuberculosis drugs, severely limiting effective treatment options. For unknown reasons, persons co-infected with HIV are particularly susceptible to TB. HIV-positive individuals are more likely to acquire primary TB disease upon initial infection, reactivate a latent TB infection, and experience an accelerated course of fatal disease when infected with a multi-drug resistant strain. Resolution of the current TB epidemic will require prevention of new TB infection as well as improved methods for treating existing disease. A better understanding of how tubercle bacilli establish infection at the cellular and molecular levels should facilitate the design of both new vaccines and treatment approaches.

140. CNN.com - Health - Disney Worker Diagnosed With TB - March 22, 2001 CNN http://cnn.com/2001/HEALTH/conditions/03/22/disney.tuberculosis/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe set your edition Languages Spanish Portuguese German Italian Danish Japanese Korean Arabic Time, Inc. Time.com People Fortune EW Disney worker diagnosed with TB ORLANDO, Florida (CNN) The Orange County Health Department is awaiting test results from several employees at Walt Disney World's Magic Kingdom after another employee a costumed character was diagnosed with active tuberculosis. Health department spokesman Bill Toth said Wednesday the victim, a woman in her 20s, is under medical treatment and has been moved to a separate apartment. She was diagnosed last Friday. He said her roommates and other friends who came in close contact with her are also being tested for the bacterial, airborne disease. The test results for the roommates could be ready Thursday. ALSO WHO launches new bid to stop tuberculosis He stressed that no visitors to Disney World would have been in danger of contracting the disease. "It takes prolonged, very close contact," Toth said. The costumed characters and visitors "meet outside, so dilution of the outside air reduces the risk, and sunlight has ultraviolet properties which kill the bacteria."

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