41. SLE - Systemic Lupus Erythematosus (Lupus) systemic lupus erythematosus, often shortened to Lupus or SLE, Systemic lupuserythematosus (SLE) is classified as a rheumatic disease. http://renux.dmed.ed.ac.uk/EdREN/EdRenINFObits/LupusNonRen.html

Systemic lupus erythematosus from EdREN , the website of the Renal Unit of the Royal Infirmary of Edinburgh Systemic lupus erythematosus, often shortened to Lupus or SLE , is one of the 'autoimmune' diseases that can affect a wide variety of organs. This information is about lupus in general, and comes from Arthritis Care . See also our information on SLE and the kidneys What is lupus? What will happen to me? Who gets lupus? ... What is the treatment? What is lupus? Systemic lupus erythematosus is a disease of the immune system - the system that prevents and fights infection. In lupus the immune system becomes unbalanced resulting in the body reacting against healthy tissue. This is why the symptoms of lupus can vary so much. Occasionally the disease is caused by using certain drugs. This is known as drug-induced lupus. Systemic lupus erythematosus (SLE) is classified as a rheumatic disease. It can cause inflammation in the joints and several of the body's organ systems. (For example: the skin, the kidneys and various other internal organs.) Hence the term systemic. The term 'lupus erythematosus' refers to the red rash on the face. Discoid lupus affects the skin and is a relatively mild disease. Sometimes it is treated by a rheumatologist (a specialist in arthritis and rheumatic disease) but more commonly by a dermatologist (a specialist in skin disorders).

42. Systemic Lupus Erythematosus (SLE) ICD9-CM 710.0 systemic lupus erythematosus SEE ALSO. Anemia, autoimmune hemolytic Glomerulonephritis, membranous. REFERENCES; Kelley WN, Harris ED, http://www.5mcc.com/Assets/SUMMARY/TP0896.html

Systemic lupus erythematosus (SLE) DESCRIPTION: A multi-system, autoimmune inflammatory condition characterized by a fluctuating, chronic course. Varies from mild to severe and may be lethal (CNS and renal forms). System(s) affected: Hemic/Lymphatic/Immunologic, Nervous, Renal/Urologic, Endocrine/Metabolic, Skin/Exocrine, Gastrointestinal, Musculoskeletal Genetics: Markers: HLA-B8; HLA-DR2; HLA-DR3 Incidence/Prevalence in USA: Predominant age: All ages, but 30-50 are most common Predominant sex: CAUSES: Most cases are idiopathic Drugs - drug induced lupus is clinically different from idiopathic SLE Synonyms: SLE Disseminated lupus erythematosus ICD-9-CM: 710.0 Systemic lupus erythematosus SEE ALSO: Anemia, autoimmune hemolytic Glomerulonephritis, membranous REFERENCES: Kelley WN, Harris ED, Ruddy S, Sledge CB: Textbook of Rheumatology. 4th Ed. Philadelphia, W.B. Saunders Co., 1993 Kippel JH, Dippe PA, eds: Rheumatology, St. Louis, Mosby, 1994 Tan FK, Arnett FC: The genetics of lupus. Curr Opin in Rheumatol 1998;10(4):399-408 Godfrey T, et al: Therapeutic advances in SLE. Curr Opin in Rheumatol 1998;10(4):435-41

43. Lupus Erythematosus Discoid Lupus Erythematosus The definitive explanation, from the Merck Manualonline. The Eye and systemic lupus erythematosus http://rarediseases.about.com/od/lupus/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a70' About Rare / Orphan Diseases Rare Diseases I - L Rare Diseases: L Lupus Rare Diseases Essentials Rare Diseases: Basic Information Rare Diseases Support Groups ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/7.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Rare / Orphan Diseases newsletter! See Online Courses Search Rare / Orphan Diseases Lupus Erythematosus A chronic inflammatory autoimmune connective tissue disease. It is not rare. Alphabetical Recent Lupus Foundation of America Main site with information and links to local chapters. Dermatologic Image Database Photos of lupus, from the Dept. of Dermatology - University of Iowa College of Medicine. Discoid Lupus Erythematosus The definitive explanation, from the Merck Manual online. The Eye and Systemic Lupus Erythematosus Sensitive to circulation problems, the eye can be affected by SLE. A technical, comprehensive article by W. Kevin Thomas, M.D. More Categories Up a category Lupus Home Pages (8) Topic Index Email to a Friend ... Patent Info.

44. Systemic Lupus Erythematosus (SLE) a CHORUS notecard document about systemic lupus erythematosus (SLE) http://chorus.rad.mcw.edu/doc/00855.html

CHORUS Collaborative Hypertext of Radiology Multisystem entities About CHORUS Search Feedback systemic lupus erythematosus (SLE) thoracic involvement (30-70%) lupus pneumonitis (acute): patchy, peripheral, basilar, alveolar interstital reticulation in lower lung fields (chronic) cavitary nodules (vasculitis) pleural changes (most common manifestation): effusion, thickening pericardial effusion (pericarditis) / cardiomegaly (cardiomyopathy) musculoskeletal arthrits (95%): subluxation without erosions AVN ; intrinsically or secondary to steroids kidneys (100%) focal membranous glomerulonephritis aneurysms in interlobar and arcuate arteries (similar to polyarterits nodosa normal/decreased renal size increased parenchymal echogenicity Yong H. Hahn, MD - 2 February 1995 Last updated 26 May 2004 Related CHORUS documents: avascular necrosis (AVN) subluxation without erosion polyarteritis nodosa acalculous cholecystitis ... rheumatoid arthritis: joint manifestations Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

45. Cutaneous Lupus Erythematosus. DermNet NZ Lupus Erythematosus (LE) of the skin comprises an uncommon group of skin may be part of an uncommon disease called systemic lupus erythematosus (SLE). http://dermnetnz.org/immune/cutaneous-lupus.html

@import url("/common/screen.css"); DermNet NZ Ad Authoritative facts about the skin from the New Zealand Dermatological Society Incorporated Home For patients For doctors ... Site map Search: Home Immune Cutaneous lupus erythematosus Lupus Erythematosus (LE) of the skin comprises an uncommon group of skin disorders including: Discoid LE Subacute LE Lupus profundus Neonatal LE ... Jessner's lymphocytic infiltrate may also be a type of cutaneous lupus. Cutaneous LE most often affects young adult women (aged 20 to 50). Cutaneous LE can be provoked by sunlight but it is actually more common in dark skinned than in fair skinned people. Sunscreens do not totally prevent it. Discoid LE In the most common form, discoid LE, unsightly red scaly patches develop which leave white scars. Discoid LE predominantly affects the cheeks and nose, but sometimes involves the upper back, V of neck, and backs of hands. Bald areas can develop if the hair follicles are involved. Discoid LE may affect the lips causing ulcers and scaling. Extensive discoid LE Discoid LE of scalp Discoid LE of lips Subacute LE In subacute LE, a non-itchy ring-shaped dry rash appears on the upper back and chest, often following sun exposure. It includes the following clinical types:

46. Systemic Lupus Erythematosus - Vitacost systemic lupus erythematosus (SLE) is an autoimmune illness that causes acharacteristic butterflyshaped rash on the face accompanied by inflammation of http://www.vitacost.com/science/hn/Concern/Lupus.htm

My account View cart / Checkout Help Since 1994 Over 1.5 Million Served! Email us Enter keyword or item number Products Health Library Clearance New Products Products Categories ... VitaBlog New! eNewsletter Archives Your Right to Privacy Customer Service Ordering Methods Shipping Information EZShip! 5 Star Guarantee ... Download Order Forms Still have questions? Talk to one of our friendly customer service representatives using Live Chat Science Health Notes Encyclopedia Product Reviews Age Related Macular Degeneration News News Room eNewsletter Archives Vitacost News Releases Additional Resources Physician's Reference Guide and Discount Program Special Discounts walkerdiet.com drkoop.com ... Join our affiliate program! Healthnotes Index: All Healthnotes Indexes Foodnotes Health Concerns Herbal Remedies Homeopathy Recipes Recipes by Course Recipes by Main Ingredient Recipes International Recipes Seasonal Safetychecker Skin Conditions Special Diets Special Recipes Vitamin Guide Weight Control Health Center Search Healthnotes: Systemic Lupus Erythematosus Also indexed as: Discoid Lupus Erythematosus (DLE), DLE, Lupus, SLE

47. LupusNY.org - Systemic Lupus Erythematosus Foundation LupusNY.org, the online home of the SLE Lupus Foundation, provides informationon lupus diagnosis, treatment, and research as well as programs and support http://www.lupusny.org/

Young Professionals Party @ Hué Thursday, September 15th 2005 7:00 PM – 10:00 PM More iPod Promotion: All guests who purchase their tickets prior to the event will be entered into an exclusive raffle for an iPod mini, sponsored by Tek Serve. In order to be included in this special raffle, you MUST purchase your ticket before September 15th! Purchase Tickets Take the Tour! Learn about Lupus S.L.E. Lupus Foundation to Help New Yorkers “Get into the Loop” on Lupus Go Tour NYC’s major hospitals in all 5 boroughs to learn how lupus affects the body. Get the latest from lupus experts, information on support services + giveaways, refreshments and more! September Stops: Manhattan- Hospital for Joint Diseases Saturday, 9/17 9:30 AM – Noon Bronx- Jacobi Medical Center Thursday, 9/29 6 PM – 8:30 PM More The latest news in lupus drug development and research. More GlaxoSmithKline to Co-Develop LymphoStat-B Study Shows Plastics Ingredient Triggers Lupus in Mice Hormone Replacement Not Associated with Severe Lupus Flares Six Additional New Investigator Grants Awarded to New York Area Scientists Go Foundation sends 33 New York-area families to Camp Sunshine More Find out more about the Foundation's Northern Manhattan and Bronx community-based multi-cultural programs.

48. Introduction: Lupus - WrongDiagnosis.com Introduction to Lupus as a medical condition including symptoms, diagnosis, Lupus Lupus (also called systemic lupus erythematosus or SLE) is a disorder http://www.wrongdiagnosis.com/l/lupus/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Lupus Next sections Basic Summary for Lupus Prevalence and Incidence of Lupus Prognosis of Lupus Types of Lupus ... Prevalence of Types of Lupus Next chapters: Discoid lupus erythematosus Neonatal lupus Addison's Disease Adrenal insufficiency ... Feedback Introduction: Lupus Lupus: Lupus is an autoimmune disease affecting mostly women and causing various effects throughout different parts of the body. Its severity can range from very mild to extremely serious depending on which body organs are afflicted. Lupus is difficult to diagnose and often misdiagnosed unless there is a characteristic symptom such as the butterfly-shaped rash over the cheeks. There is no single definitive blood test for lupus and doctors have to make the diagnosis based on a variety of symptoms and diagnostic tests . Lupus is one of a group of conditions with vague symptoms such as fatigue or malaise , and may need to be distinguished from fibromyalgia chronic fatigue syndrome Type 2 diabetes depression ... multiple sclerosis , or various other conditions. If the main symptoms are

49. Systemic Lupus Erythematosus Penn State Hershey Medical Center provides world class care and services to patients. http://www.hmc.psu.edu/healthinfo/jkl/lupus.htm

50. Systemic Lupus Erythematosus - Health Information Health information discussing systemic lupus erythematosus (SLE) which is achronic inflammatory disease that may variably affect multiple organ systems. http://www.mckinley.uiuc.edu/health-info/dis-cond/misc/lupus.html

Go to PDF Version Systemic Lupus Erythematosus WHAT IS SYSTEMIC LUPUS ERYTHEMATOSUS? Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may variably affect multiple organ systems - musculoskeletal, dermatologic (skin), hematologic (blood related), cardiac, pulmonary, renal (kidney), and central nervous systems. Patients with SLE have an impaired immune system that is unable to distinguish foreign or abnormal cells from normal healthy tissue. It begins to produce auto-antibodies that react with and destroy normal tissue, rather than attacking foreign cells or antigens. This abnormal immune response produces immune complexes, which, when deposited and trapped in organ tissue cause damage to a variety of organ systems. WHO IS AT RISK FOR DEVELOPING SLE? The cause is unknown, but the following factors have been associated with SLE: Genetics (high concordance in identical twins) Hormonal factors (higher frequency in females, decreased risk with breast-feeding, increased risk of other hormone related diseases) Immunologic factors (loss of self-tolerance) Environmental factors (viruses/other microbes, UV light, silica dust, cigarettes, medications, and medication allergies)

51. Lupus Erythematosus - Wikipedia, The Free Encyclopedia Lupus erythematosus (also known as systemic lupus erythematosus or SLE) is anautoimmune systemic lupus erythematosus and accelerated atherosclerosis . http://en.wikipedia.org/wiki/Lupus_erythematosus

You did it! Over US$240,000 was donated in the 21-day fund drive. Thank you for your generosity! You are still welcome to make a donation or purchase Wikimedia merchandise Lupus erythematosus From Wikipedia, the free encyclopedia. Lupus erythematosus Lupus erythematosus (also known as systemic lupus erythematosus or SLE ) is an autoimmune disorder in which antibodies are created against the patient's own DNA . It is named for the Latin lupus , meaning " wolf ," due to the butterfly-shaped rash that the disease classically creates on the cheek which medieval people believed to resemble a wolf bite. Contents Signs and symptoms Dermatological manifestations Musculoskeletal manifestations Hematological manifestations ... edit Signs and symptoms Common initial and chronic complaints are fever malaise myalgias and fatigue , Because they are so often seen with other diseases, these signs and symptoms are not part of the diagnostic criteria for SLE, but when occurring in conjunction with other signs and symptoms, they are considered suggestive. edit Dermatological manifestations As many as 30% of patients present with some dermatological symptoms (and 65% suffer such symptoms at some point), but only 30% to 50% suffer the classic malar (or

52. FCIC: Lupus systemic lupus erythematosus. US Department of Health and Human Services This booklet is for people who have systemic lupus erythematosus, http://www.pueblo.gsa.gov/cic_text/health/lupus/contents.html

Systemic Lupus Erythematosus U.S Department of Health and Human Services National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases Contents Defining Lupus Symptoms of Lupus Diagnosing Lupus Treating Lupus ... Additional Resources This booklet is for people who have systemic lupus erythematosus, commonly called SLE or lupus, as well as for their family and friends and others who want to better understand the disease. The booklet describes the disease and its symptoms and contains information about diagnosis and treatment as well as current research efforts supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other components of the Department of Health and Human Services' National Institutes of Health (NIH). It also discusses issues such as health care, pregnancy, and quality of life for people with lupus. If you have further questions after reading this booklet, you may wish to discuss them with your doctor. PDF Version Printer-friendly Version

53. Systemic Lupus Erythematosus CHC Wausau Hospital s Medical Library and Patient Education Center providesresearch services and healthcare information to physicians, http://www.chclibrary.org/micromed/00067210.html

Main Search Index Definition Description Causes ... Resources Systemic lupus erythematosus Systemic lupus erythematosus (SLE) is an autoimmune disease in which the individual's immune system attacks, injures, and destroys the body's own organs and tissues. Nearly every system of the body can be affected by SLE, as depicted in the illustration above. (Illustration by Electronic Illustrators Group.) Definition Systemic lupus erythematosus (also called lupus or SLE) is a disease where a person's immune system attacks and injures the body's own organs and tissues. Almost every system of the body can be affected by SLE. Description The body's immune system is a network of cells and tissues responsible for clearing the body of invading foreign organisms, like bacteria, viruses, and fungi. Antibodies are special immune cells that recognize these foreign invaders, and begin a chain of events to destroy them. In an autoimmune disorder like SLE, a person's antibodies begin to recognize the body's own tissues as foreign. Cells and chemicals of the immune system damage the tissues of the body. The reaction that occurs in tissue is called inflammation. Inflammation includes swelling, redness, increased blood flow, and tissue destruction. In SLE, some of the common antibodies that normally fight diseases are thought to be out of control. These include antinuclear antibodies and anti-DNA antibodies. Antinuclear antibodies are directed against the cell's central structure that contains genetic material (the nucleus). Anti-DNA antibodies are directed against the cell's genetic material. DNA is the chemical substance that makes up the chromosomes and genes.

54. Systemic Lupus Erythematosus Links to resources relating to systemic lupus erythematosus, also known as eitherlupus or SLE. http://www.healthinsite.gov.au/topics/Systemic_Lupus_Erythematosus

Skip to Content Advanced Search About Health Insite A-Z Health Topics ... Conditions and Diseases Topics such as asthma, diabetes, cancer, arthritis, depression Health and Wellbeing Topics such as fitness, nutrition, drugs, preventing suicide, health insurance, women's health, living with a disability Life Stages and Events Topics such as menopause, pregnancy, ageing, going into hospital Health Services Includes links to State/Territory Health Services and other services News Health Insite Newsletter ... Home Systemic Lupus Erythematosus Lupus occurs in several types, including systemic lupus erythematosus (SLE), discoid and drug-induced. SLE is the most common type and causes the most difficulties. It can lead to problems such as fever, swollen joints, anaemia and kidney failure. Lupus is most commonly diagnosed when people are between 15 and 45 years old. Follow the links below to information on systemic lupus erythematosus or SLE. Updated May 2005 Printer friendly page 10 Resources Found Results 1 to 10 displayed.

55. ► Systemic Lupus Erythematosus A medical encycopedia article on the topic systemic lupus erythematosus. http://www.umm.edu/ency/article/000435.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Z Maryland Medical Center Programs Maryland Heart Center Home Medical Reference Encyclopedia (English) Toggle English Spanish Systemic lupus erythematosus Overview Symptoms Treatment Prevention Definition: A chronic, inflammatory autoimmune disorder that may affect many organ systems including the skin, joints, and internal organs. Alternative Names: Disseminated lupus erythematosus; SLE; Lupus; Lupus erythematosus Causes, incidence, and risk factors: Normally the immune system controls the body's defenses against infection. In systemic lupus erythematosus (SLE) and other autoimmune diseases , these defenses are turned against the body when antibodies are produced against its own cells. These antibodies fight against the body's blood cells, organs, and tissues, causing chronic diseases. The mechanism or cause of autoimmune diseases is not fully known. The disease affects 9 times as many women as men. It may occur at any age, but appears mostly in people between the ages of 10 and 50 years. SLE may also be caused by certain drugs. When this occurs, it is known as drug-induced lupus erythematosus and is usually reversible when the medication is stopped.

56. Systemic Lupus Erythematosus - UMMC An indepth report on the causes, diagnosis, treatment, and prevention of Lupus. http://www.umm.edu/patiented/articles/what_symptoms_of_systemic_lupus_erythemato

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Home Medical Reference Patient Education WHAT ARE THE SYMPTOMS OF SYSTEMIC LUPUS ERYTHEMATOSUS? SLE symptoms may develop imperceptibly over months or years, or they may appear suddenly. Symptoms tend to be worse during winter months, perhaps because prolonged exposure to sunlight in the summer causes a gradual build-up of factors that trigger symptoms months later. Arthritic Pain The most common symptom is joint pain, occurring in about 90% of SLE patients. Characteristics of this symptom vary widely: It is often accompanied by swelling and redness. It can last from hours to months. It may be mild or severe. It can occur in one joint, move from one to another, or flare erratically. Pain often occurs in the morning and improves during the day, only to return later when the patient tires. The joints most affected are fingers, wrists, elbows, knees, and ankles. (Joints in the spine and neck are not affected.) Children may experience these symptoms as growing pains, and, in all patients, they may be the only symptoms for many years. Fever Fever occurs in 90% of SLE patients and is usually caused by the inflammatory process of the disease, not by infection. It is low-grade except during an acute lupus crisis.

57. InteliHealth: Lupus Erythematosus systemic lupus erythematosus, commonly called lupus or sometimes SLE, In contrast to systemic lupus erythematosus, which involves many organs, http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10276.html

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58. Systemic Lupus Erythematosus systemic lupus erythematosus (also called lupus or SLE) is a disease where aperson s immune system attacks and injures the body s own organs and tissues. http://www.healthatoz.com/healthatoz/Atoz/ency/systemic_lupus_erythematosus.jsp

59. Systemic Lupus Erythematosus This page has information about systemic lupus erythematosus. http://www.mcgill.ca/hostres/diseases/lupus/

var GJSBrowserName = 'Unknown'; var mcgilllogo_Off = new Image(119,29); mcgilllogo_Off.src = "http://upload.mcgill.ca/global/new_options/mcg_0.gif"; var mcgilllogo_On = new Image(119,29); mcgilllogo_On.src = "http://upload.mcgill.ca/global/new_options/mcg_1.gif"; var sectionlink_Off = new Image(136,53); sectionlink_Off.src = "http://upload.mcgill.ca/global/sections/sectionlink510_en_0.gif"; var sectionlink_On = new Image(136,53); sectionlink_On.src = "http://upload.mcgill.ca/global/sections/sectionlink510_en_1.gif"; Sign in Friday, September 9, 2005 Prospective students Student information ... Larger Smaller Sign in Home Faculty of Medicine Host Resistance ... Septic shock Systemic lupus erythematosus Tuberculosis Information for students Research partners Communications ... Training Centre Systemic lupus erythematosus Systemic lupus erythematosus (SLE), commonly known as Lupus, is a very old disease and was first named 135 years ago. It got its name from the very distinctive facial rash that gives a person the appearance of having been attacked by a wolf. The facial rash, which is also known as a butterfly rash, can occur after exposure to sunlight. This, however, is only one of the many different features of this autoimmune disease, which can affect almost every organ system. Lupus has been referred to as the disease with 1,000 faces. Lupus is relatively rare, affecting approximately 1 per 1,000, of whom 95% are women. It is more common in Africans, American Indians and Asians than in Caucasians. The disease can occur at any age, but typically starts in 20- to 30-year-old individuals. What causes the disease is unknown; however, many genes as well as the environment likely contribute to susceptibility and disease course.

60. Systemic Lupus Erythematosus systemic lupus erythematosus (SLE) is a chronic, inflammatory . It may affectmany organ systems including the skin, joints, and internal organs. http://www.healthcentral.com/ency/408/000435.html

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