121. BBC - Relationships - Sex And Sexual Health - Syphilis All the facts about syphilis. If you d like to see what the effects of syphilis look like on the skin, click on any of the links below. http://www.bbc.co.uk/relationships/sex_and_sexual_health/stis_syphilis.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Relationships ... Help Like this page? Send it to a friend! Syphilis It may sound like a disease that died out in the 19th century, but syphilis is still well and truly with us.and can have devastating effects if left untreated, says the fpa . But how do you catch it and what are the symptoms? In this article What is it and how is it passed on? Signs and symptoms What happens if it isn't treated? Testing and treatment ... How to avoid STIs What is it and how is it passed on? Syphilis is a bacterial infection, sometimes called 'the pox'. It has several stages: primary and secondary stages, which are very infectious, and the third or latent stage, which occur if the infection is left untreated. Syphilis is easily passed on through: vaginal, oral or anal sex sharing sex toys intimate close body contact with syphilis sores or rashes from a mother to her unborn baby You can't catch syphilis from hugging, sharing baths or towels, or from toilet seats or swimming pools. Signs and symptoms The symptoms of syphilis can be difficult to recognise and can be missed. They can take up to three months to show after sex with an infected person.

122. BBC - Health - Conditions - Syphilis of syphilis, its causes, symptoms and treatment....... http://www.bbc.co.uk/health/conditions/syphilis1.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index FRIDAY 9th September 2005 Text only BBC Homepage Lifestyle Health ... Help Like this page? Send it to a friend! Syphilis Dr Rob Hicks Syphilis is a bacterial infection that usually affects the genitals. If left untreated, it can affect other parts of the body and may be fatal. In this article How's it caused? What are the symptoms? How many people are affected? Prevention ... Treatment How's it caused? It's caused by the bacterium called treponema pallidum that enters the body through the mucous membranes of the genital area or the skin. What are the symptoms? Symptoms develop in three stages. In the primary stage, symptoms may take up to 12 weeks to appear after infection. One or more painless sores (chancres) appear at the place where the infection entered the body. In women, they may appear on the vulva, the clitoris, around the opening of urethra, or on the cervix. In men they may appear on the penis or the foreskin. In men and women they may appear around the anus and mouth and the sores may take between two to six weeks to heal. The secondary stage develops within the next two years if the infection isn't treated. Symptoms include:

123. Untitled These were to revolutionise the treatment of syphilis. The following account of the treatment of syphilis is taken from the Practitioner s http://www.ku.edu/carrie/specoll/medical/syphilis.htm

SYPHILIS In 1906 Paul Ehrlich, the famous German physician, who died in 1915, discovered Salvarsan 606 and Neosalvarsan 614, the world's first chemotherapeutic agents for systemic treatment of a micro-organism. These were to revolutionise the treatment of syphilis. For centuries before Salvarsan, treatment was by the use of mercury and iodides but these medications usually failed to prevent the disease progressing over the years to the incurable tertiary stages. It is of interest that in 1915, nine years after the discovery of Salvarsan, mercury was still prescribed by injection and inunction. Despite the availability of a specific cure, and the use of the Wassermann test for diagnosis, syphilis was a major problem affecting the health of soldiers on the Western Front; I recall treating an aged lady in 1986 who had developed a manifestation of tertiary syphilis. Her primary infection, in 1919, of which she was unaware, was from her husband who had returned to Australia from the Western Front. The following account of the treatment of syphilis is taken from the "Practitioner's Encyclopaedia of Medical Treatment" published in 1915 by Oxford Medical Publications. Intravenous injections are commonplace today but they were rarely used at the beginning of the century and Mr McDonough, FRCS., the author of the article quoted below, obviously considered it to be important to describe in detail how they should be given.

124. Pictures: Syphilis PICTURES syphilis. line syphilis before treatment, one, and two weeks of treatment with antibiotics. back to images directory. http://www.healthac.org/images/syphilis.html

PICTURES: SYPHILIS Syphilis before treatment, one, and two weeks of treatment with antibiotics. back to images directory

125. Discovery Channel :: News :: Shakespeare Poisoned By Syphilis Treatme A doctor builds a case that mercury used to treat Shakespeare s syphilis contributed to his death. http://dsc.discovery.com/news/briefs/20050117/shakespeare.html

postionList = "x21,x24,TopLeft,x25,x12"; OAS_RICH("TopLeft"); September 09, 2005 EDT Discovery News Article expand Shakespeare at an Advanced Age Shakespeare Poisoned by Syphilis Treatment? By Jennifer Viegas, Discovery News Jan. 19, 2005 The theories, published in the Feb. 1 edition of the journal Clinical Infectious Diseases , may explain why Shakespeare (1564-1616) could have had a Parkinson-like tremor later in his life, why he apparently withdrew from social situations, and why the famed writer might have experienced some baldness at a relatively early age. expand The Bard as a Young Man Shakespeare had a knowledge of syphilis that was clinically exact. Go Deeper Choose your path into the past with the History Guide. Read about researchers working in the field featured in our Discovery Quest series. Related News Officials Ban Love Letters on Juliet's House Disguise the Norm in 18th-Century Venice Book: Who Killed Chaucer? To support the claims, Dr. John Ross, of the Division of Infectious Diseases at Caritas St. Elizabeth's Medical Center in Boston, points to four primary lines of evidence: the prevalence of syphilis in Shakespeare's England; the bard's interest in, and knowledge of, STDs; documentation by and about Shakespeare; and his physical appearance. Surviving hospital records indicate that English hospitals during the mid to late 16th century were flooded with syphilis patients. In 1579, one physician wrote that 75 percent of patients were being treated for "the French pox," a reference to syphilis.

126. IU Bloomington: Poynter Center This resource presents an overview of syphilis and its treatments through The origins of syphilis have been a subject of much contentious debate. http://poynter.indiana.edu/sas/lb/syphilis.html

Poynter search: About the Center News and announcements Public events Staff and contact Publications Major Projects Association for Practical and Professional Ethics The Least of My Brothers Teaching Research Ethics Scientists and Subjects ... IU Bloomington Home Poynter Center for the Study of Ethics and American Institutions The file you tried to reach is not at the specified URL. In about five seconds, this page will automatically redirect you to the Poynter Center home page at http://poynter.indiana.edu/ . Please update your bookmarks and links. Poynter Center for the Study of Ethics and American Institutions 618 East Third Street, Bloomington IN 47405-3862 Last updated: 31 October 2003 URL: http://poynter.indiana.edu/redirect.shtml Comments: poynter@indiana.edu , The Trustees of Indiana University

127. Syphilis And HIV Primary, Secondary, and Early Latent syphilis in HIVInfected Patients Follow-Up of HIV-Infected Patients Treated for syphilis http://hivinsite.ucsf.edu/InSite?page=kb-05&doc=kb-05-01-04

128. Syphilis Treatment Options The gold standard for treatment of syphilis is consecutive daily The role of benzathine penicillin in the treatment of syphilis warrants special mention http://www.medicineau.net.au/clinical/sexualhealth/syphillis.html

Sexual Health Au Syphilis Treatment Options Dr Kieran Mutimer Resources Columns Computing Clinical Aboriginal Health Adolescent Medicine Anaesthetics Complementary Medicine Dermatology Drugs and Alcohol Emergency ENT Geriatrics ICU Internal Medicine Musculoskeletal Paediatrics Palliative Care Psychiatry Surgery Women's Health Sexual Health Human Papilloma Virus Syphilis Treatment Options Syphilis Treatment Options Table of Contents Procaine penicillin Benzathine penicillin Syphilis and the pregnant patient Alternative treatment regimes ... Summary Procaine penicillin The gold standard for treatment of syphilis is consecutive daily intramuscular injections with procaine penicillin. The dosage and duration of treatment are determined by the clinical presentation. e.g. chancre, secondary mucocutaneous manifestations, neurosyphilis, etc. If no clinical staging is possible (as is usually the case), serological staging (e.g. RPR or VDRL titres) determines the treatment regime. There are a number of treatment options for patients who are allergic to penicillin, who are needle-phobic or who may not comply with a course of daily injections. These treatment options have not been as well studied as the procaine penicillin regimes but are totally acceptable alternatives. Benzathine penicillin The role of benzathine penicillin in the treatment of syphilis warrants special mention. Benzathine penicillin (marketed in Australia by Wyeth as bicillin L-A 1.8gm/4ml syringe) for I.M. injection as a single injection will adequately treat primary and secondary syphilis, or sero positive syphilis with a VDRL or RPR titre of 1:16 or higher. This regime is much more user friendly than a 10 day use of I.M. procaine penicillin and compliance is not an issue. This same dose can be given to sexual contacts of the above groups as epidemiological treatment. As benzathine penicillin DOES NOT cross the blood brain barrier it is only suitable for use in treating latent syphilis (VDRL or RPR titre

129. Syphilis: Old Problem, New Strategy -- Doherty Et Al. 325 (7356): 153 -- BMJ syphilis is on the increase again. Lorraine Doherty and colleagues report New cases of infectious syphilis in genitourinary medicine clinics in England http://bmj.bmjjournals.com/cgi/content/full/325/7356/153

document.write(''); Home Help Search Archive ... Table of Contents Author Keyword(s) Vol Page [Advanced] This article Extract PDF Respond to this article Read responses to this article ... View citation map Services Email this article to a friend Find similar articles in BMJ Find similar articles in ISI Web of Science Find similar articles in PubMed ... Read articles citing this article Search for citing articles in: ISI Web of Science (33) PubMed PubMed Citation Articles by Doherty, L. Articles by Palfreeman, A. Related content Other Public Health Sexually Transmitted Infections - other than HIV / AIDS Related Articles BMJ 2002;325:153-156 ( 20 July ) Education and debate Syphilis: old problem, new strategy Lorraine Doherty consultant epidemiologist a Kevin A Fenton consultant epidemiologist a Jane Jones specialist registrar in public health medicine a Thomas C Paine senior scientist a Stephen P Higgins consultant in genitourinary medicine b Deborah Williams consultant in genitourinary medicine c Adrian Palfreeman consultant in genitourinary medicine d a HIV/STI Division, PHLS Communicable Disease Surveillance Centre, London NW9 5EQ

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