101. Syphilis Overview of syphilis, a sexually transmitted disease (STD). Related Test Pap Smear. Can be treated with antibiotics. If left untreated, can cause organ http://www.labtestsonline.org/understanding/conditions/syphilis.html

TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

102. Syphilis: The Test The test is used to diagnose infection with syphilis in sexually active persons. If a scraping reveals presence of the syphilis bacterium (a positive http://www.labtestsonline.org/understanding/analytes/syphilis/test.html

TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

103. Syphilis CHC Wausau Hospital s Medical Library and Patient Education Center provides research services and healthcare information to physicians, http://www.chclibrary.org/micromed/00067190.html

Main Search Index Definition Description Causes ... Resources Syphilis Definition Syphilis is an infectious systemic disease that may be either congenital or acquired through sexual contact or contaminated needles. Description Syphilis has both acute and chronic forms that produce a wide variety of symptoms affecting most of the body's organ systems. The range of symptoms makes it easy to confuse syphilis with less serious diseases and ignore its early signs. Acquired syphilis has four stages (primary, secondary, latent, and tertiary) and can be spread by sexual contact during the first three of these four stages. Syphilis, which is also called lues (from a Latin word meaning plague ), has been a major public health problem since the sixteenth century. The disease was treated with mercury or other ineffective remedies until World War I, when effective treatments based on arsenic or bismuth were introduced. These were succeeded by antibiotics after World War II. At that time, the number of cases in the general population decreased, partly because of aggressive public health measures. This temporary decrease, combined with the greater amount of attention given to AIDS in recent years, leads some people to think that syphilis is no longer a serious problem. In actual fact, the number of cases of syphilis in the United States has risen since 1980. This increase affects both sexes, all races, all parts of the nation, and all age groups, including adults over 60. The number of women of childbearing age with syphilis is the highest that has been recorded since the 1940s. About 25,000 cases of infectious syphilis in adults are reported annually in the United States. It is estimated, however, that 400,000 people in the United States need treatment for syphilis every year, and that the annual worldwide total is 50 million persons.

104. DermAtlas: Online Dermatology Image Library Dermatology Image,syphilis, Primary, DermAtlas Dermatology Images syphilis,syphilis,syphilis,syphilis,syphilis, syphilis,syphilis,syphilis,syphilis,syphilis,syphilis,syphilis,syphilis http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=-1633004062

105. RADIONUCLIDE IMAGING IN SYPHILIS This can last 10 to 30 years; tertiary syphilis will then develop in about Gummata are seen in tertiary syphilis and in all recent case reports have http://www.med.harvard.edu/JPNM/BoneTF/Case11/WriteUp11.html

RADIONUCLIDE IMAGING IN SYPHILIS Edward B. Cronin, M.D. Donald E. Tow, M.D. Walter H. Williams, M.D. May 13, 1986 Case Presentation: A 39 year-old male presented to the EW with an eight month history of worsening back and right should pain accompanied by a twenty pound weight loss. Radiographs in the EW demonstrated multiple lytic and blastic lesion to the spine ( A-P and lateral ) and destruction of the right glenoid arrow ); he was then admitted for workup of presumed metastitic carcinoma. Twenty years earlier, he had undergone an orchiectomy for an undescended testicle and had been treated in 1967 for urethritis while in Vietnam. Physical examination was remarkable only for hepatomegaly. His hematocrit was 36%, ESR 122mm/hr, iron 18, TIBC 204, alkaline phosphatase 199; other liver function studies were normal. CEA, AFP, SPEP and B-HCG levels were normal. A Tc-99m MDP bone scintigram demonstrated multiple regions of increased and decreased activity ( right shoulder left shoulder LS spine ); a Tc-99m sulfur colloid liver spleen scan showed hepatomegaly with multiple focal liver defects. A CT scan confirmed the presence of liver defects and destructive change in the spine. A bone biopsy was unsuccessful and two liver biopsies yielded no neoplastic cells. He underwent an exploratory laparotomy and was found to have several caseous liver masses, but no tumor. An infectious etiology was felt most likely and syphilis serologies were obtained. The RDRL was positive at 1:128, FTA-abs 4+ and CSF VDRL was also positive. He was begun on penicillin therapy. Following treatment, he had resolution of his back pain and began to gain weight.

106. Complications: Syphilis syphilis is a serious sexually transmitted infection. It is caused by a bacterium. If a pregnant woman has syphilis and she is not treated, http://www.marchofdimes.com/pnhec/188_708.asp

View All Chapters Find Your Local Chapter September 9, 2005 Before You're Pregnant During Your Pregnancy Complications Caring for Your Baby ... [View All Articles] Syphilis What you need to know: Syphilis is a serious sexually transmitted infection. It is caused by a bacterium. Syphilis can infect both a woman and her fetus during pregnancy. Syphilis is less common than other sexually transmitted infections in the United States. In 2002, health officials reported over 32,000 cases of syphilis. Syphilis begins with a painless sore, often in the genital or vaginal area. Sores can also appear on the anus, in the mouth or on the lips. Weeks or months later, infected persons can develop a rash, fever and other symptoms. If the disease is untreated, the heart, brain and other organs can be damaged. Health care providers diagnose syphilis by examining material from a sore under the microscope. Blood tests are also used. Syphilis is treated with antibiotics. Most pregnant women are tested for syphilis at an early prenatal visit . A single injection of penicillin can cure syphilis if the woman has had the infection for less than one year. Older infections require more treatment. If a pregnant woman has syphilis and she is not treated, her baby can become infected and may even die. Infected babies who are not treated soon after birth are at risk for serious health problems, including brain damage and blindness.

107. Atlas Of Dermatology syphilis, Clinical picture (1055). Pictures. Secondary syphilis, large amount of typical spiralshaped spirochetes Treponema pallidum http://atlases.muni.cz/atl_en/main dermven syph.html

108. SYPHILIS syphilis. DESCRIPTION . A treatable bacterial infection that can spread throughout the body and affect the WHAT ARE THE syphilis RATES IN RHODE ISLAND? http://www.health.ri.gov/disease/communicable/std/syphilis.php

Home Health Topics News Data ... Site Map Program Activities STD Homepage Information for General Public What Everyone Should Know about STDs STD/STI Factsheets ... Other Links Office of Communicable Diseases 3 Capitol Hill Room 106 Phone: (401) 222-2577 Fax: (401) 222-2488 711 (RI Relay) Contact Us Sexually Transmitted Diseases SYPHILIS DESCRIPTION A treatable bacterial infection that can spread throughout the body and affect the heart, brain, nerves. Also known as "syph". FACT SHEETS: Centers for Disease Control Fact Sheet American Social Health Association (asha) TO SEE A PICTURE: Wadsworth Center NYS Department of Health WHO CAN I CONTACT AT THE RHODE ISLAND DEPARTMENT OF HEALTH ABOUT SYPHILIS Call the Office of Communicable Diseases at 401-222-2577 STD Treatment at Whitmarsh House WHAT ARE THE SYPHILIS RATES IN RHODE ISLAND? Highlights STD/STI Factsheets An A-Z List of Sexually Transmitted Diseases/Infections Contact Us

109. Best Practice Medicine- Professional Reference - Syphilis Infectious Diseases, syphilis. Detailed recommendations in the Report, During known syphilis outbreaks, obtain detailed information about place of http://merck.micromedex.com/index.asp?page=bpm_brief&article_id=BPM01ID22

110. It's Your Health - Diseases It s Your Health is a series of topical and brief publications produced by Health Canada for the public, media and special interest groups. http://www.hc-sc.gc.ca/english/iyh/diseases/syphilis.html

@import url(/styles/advanced.css); Français Contact us Help Search ... Diseases Diseases Here you will find current, reliable and easy-to-understand articles on the topic of diseases. There are over 100 It's Your Health articles on various topics you can download or print for free. See the complete list Avian Influenza (Bird Flu) Breast Cancer Cervical Cancer ... Whooping Cough (Pertussis) Last Updated: 2005-09-06 Important Notices

111. Congenital Syphilis a CHORUS notecard document about congenital syphilis. http://chorus.rad.mcw.edu/doc/00655.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system About CHORUS Search Feedback congenital syphilis Wimberger sign periostitis part of ToRCHS complex Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 26 May 2004 Related CHORUS documents: Wimberger sign congenital infection: ToRCHS syndrome periosteal reaction celery stalk metaphyses ... Caffey disease Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

112. Syphilis Public service reforms and their impact on health sector personnel. http://www.who.int/docstore/hiv/GRSTI/005.htm

Introduction Background Global Estimates Chlamydia estimates, 1999 ... Contents Syphilis Figure 9. Estimated new cases of syphilis among adults, 1999 Acrobat PDF) In Western Europe, syphilis prevalence has declined substantially since the peak after the second World War, with incidence rates below 5 per 100 000 in the majority of countries. In the USA, trends of congenital syphilis began to decline in 1992 after an increase that follow a national syphilis epidemic in 1980s and early 1990s. Rates of congenital syphilis declined from 78.2 in 1992 to 20.6 per 100 000 live births in 1998, with high rate in the south-eastern United States and among minority racial/ethnic populations. The trend observed is parallel with the trend for primary and secondary syphilis. Box 5. Basic facts about Syphilis Syphilis is the classic example of a STI that can be successfully controlled by public health measures due to the availability of a highly sensitive diagnostic test and a highly effective and affordable treatment. Clinical manifestations : ulceration of the uro-genital tract, mouth or rectum, If untreated, this is followed by a more generalised infection which is usually characterised by disseminated muco-cutaneous lesions. There may be fever and general malaise, as well as hair loss and mild hepatitis.

113. Syphilis Infectious syphilis consists of a primary stage and a secondary stage. Latent syphilis is an asymptomatic phase in an untreated patient, http://www.5mcc.com/Assets/SUMMARY/TP0894.html

Syphilis DESCRIPTION: A sexually transmitted infection, characterized by sequential stages (acute, subacute or chronic), with the spirochete, Treponema pallidum Infectious syphilis consists of a primary stage and a secondary stage. It may also include neurosyphilis (central nervous system involvement). If untreated, the infectious stage may be followed by a latent stage. Latent syphilis is an asymptomatic phase in an untreated patient, characterized by positive specific treponema Ab test with normal CSF. Early latent is less than 1 year and late latent is more than 1 year after onset of infection. Neurosyphilis may occur at any stage in syphilis. Primary, secondary stages usually asymptomatic; tertiary stage is symptomatic. Tertiary (or late syphilis) stage is late generalized syphilis Congenital is syphilis acquired in utero System(s) affected: Reproductive, Skin/Exocrine, Nervous, Cardiovascular Genetics: N/A Incidence/Prevalence in USA: 1989 - 18.4/100,000 new cases 1997 - 3.2/100,000 new cases (50% occurred in just 31 counties of 3115 U.S. counties) Predominant age: Sexually active years Predominant sex: CAUSES: Treponema pallidum Synonyms: Lues The Great Imitator ICD-9-CM: 097.9 Syphilis, unspecified

114. Sexually Transmitted Diseases: Syphilis A discussion of the most common STDs, along with consequenses, prevention tips, and related links. Includes info about cervical cancer, pelvic inflammatory http://www.epigee.org/health/syphilis.html

Home Main Menu STD Overview Chlamydia ... Crabs Treatment Syphilis Syphilis is a sexually transmitted disease caused by the bacteria Treponoma pallidum. It is often called the "Great Imitator" because syphilis symptoms resemble those of other common diseases. It has also been given the names "Miss. Siff" and "The Pox". Almost 36 000 cases of syphilis are reported in the United States each year but many more go unreported. The majority of syphilis sufferers are male, accounting for about 60% of all cases. If caught early on, syphilis can be easily treated. However, if left untreated, syphilis can cause heart problems, psychological disorders, blindness, and death. Syphilis also increases the risk of contracting HIV, the virus that causes AIDS, by up to five fold. Type of Infection : Bacterial Modes of Transmission : Syphilis is almost always transmitted through sexual contact with an infected person. The syphilis bacteria can easily spread from the ulcers on an infected person to the mucous linings of the mouth, genitals, and anus of an uninfected sexual partner. Though unlikely, it is possible to contract the infection by coming into contact with the broken skin of an infected person. Syphilis can also be passed from an infected mother to her unborn child. Symptoms Syphilis symptoms occur in stages. Primary syphilis results in painless sores called "chancres." These usually appear on the genitals, but they can also appear on the lips, tongue, and other body parts. These chancres generally disappear within a few weeks, but if left untreated, the disease can progress to chronic stages. Secondary syphilis begins with the syphilis rash. This is an infectious brown skin rash that typically occurs on the bottom of the feet and the palms of the hand. Fever, sore throat, swollen glands, and hair loss can also be experienced. The third stage of syphilis can last for many years, and you may suffer from joint and bone damage, increasing blindness, numbness in the extremities, or difficulty in coordinating movements.

115. Sexually Transmitted Diseases: Part 2 syphilis is a sexually transmitted infectious disease caused by the bacterium In contrast to the syphilis chancre, the chancroid is extremely painful. http://www.kcom.edu/faculty/chamberlain/Website/lectures/lecture/std2.htm

Genitourinary Tract Infections Return to Syllabus SEXUALLY TRANSMITTED DISEASES (STD) continued Diseases in this Handout: Syphilis Chancroid Genital Herpes IV. Syphilis Syphilis is a sexually transmitted infectious disease caused by the bacterium Treponema pallidum A. T. pallidum has a number of characteristics which are important for diagnosis. The spiral shaped morphology and characteristic motility pattern (they spin around their longitudinal axis in a corkscrew type manner) are important for diagnosis via darkfield microscopy. Here is a picture of the cross section of the organism. T. pallidum cannot be grown in vitro B. Epidemiology of syphilis Man is the only known host and transmission is virtually always by direct contact with infectious lesions, generally through sexual contact. The incidence is highest in sexually active people (20-29 year old group). The number and rate of 1 o and 2 o Approximately 30% of exposed people contract the disease. The South continues to have the highest rate in the country (rate: 4.5) From 1998 to 1999, rates declined 10% in the South (from 5.0 to 4.5) and 12.5% in the Northeast (0.8 to 0.7). The rate for the West remained unchanged (1.0), and the rate for the Midwest increased from 1.9 in 1998 to 2.2 in 1999.

116. Handbook Of Ocular Disease Management - Syphilis syphilis is a multisystem, multi-symptom disorder that occurs primarily through syphilis is caused by the spirochete bacteria, Treponema pallidum. http://www.revoptom.com/handbook/sect7f.htm

SYPHILIS SIGNS AND SYMPTOMS Syphilis is a multi-system, multi-symptom disorder that occurs primarily through sexual transmission, though the disease can be spread through blood transfusion and direct contact with an infected lesion. Patients tend to be younger, with a history of unprotected sex. Elderly patients may manifest late-stage syphilis left untreated many years before. In cases of congenital syphilis, the patient may manifest Hutchinson's triad (interstitial keratitis, deafness and malformed teeth), osteochondritis (inflammation of both bone and cartilage), chorioretinitis, hepatosplenomegaly (enlargement of the liver and spleen), and anorexia. In the primary stage of acquired syphilis, the patient develops a painless chancre at the site of inoculation, as well as regional lymphadenopathy. While primarily genital, chancres may develop on the eyelid and conjunctiva. Other ocular signs in the primary stage include conjunctivitis, blepharitis, and alopecia. In the secondary stage of acquired syphilis, the patient will develop malaise, lymphadenopathy, fever, maculopapular skin lesions on the palms and soles, joint pain, headache, and loss of appetite. Ocular signs are most common in secondary syphilis and include episcleritis, anterior uveitis, uveitic glaucoma, neuroretinitis, chorioretinitis, ischemic retinal vasculopathy, and infectious optic neuropathy.

117. Notifiable Condition: Syphilis Notifiable Conditions Index page for syphilis. syphilis in Washington State DOH receives 9 (1996) to 57 (2001) reports of primary and secondary syphilis http://www.doh.wa.gov/notify/nc/syphilis.htm

You are here: DOH Home Notifiable Conditions » Syphilis Index Search Employees Site Directory: Notifiable Conditions: Syphilis Other links concerning Notifiable Conditions Local Health Jurisdictions How to Report a Notifiable Condition Reporting Forms Glossary ... EpiTrends Posters (PDF, 645KB) (PDF, 529KB) (PDF, 314KB) (PDF, 117KB) (PDF, 129KB) Associated Programs Communicable Disease Epidemiology WEDSS (Washington Electronic Disease Surveillance System) PDF documents require the free Acrobat Reader. Click here to download a copy Syphilis Syphilis in Washington State DOH receives 9 (1996) to 57 (2001) reports of primary and secondary syphilis per year. Purpose of Reporting and Surveillance To assure the adequate treatment of infected individuals in order to curtail infectiousness and prevent sequelae of infection. To identify, contact, and treat sexual contacts of reported cases in order to break the chain of transmission.

118. Syphilis Sexually Transmitted Diseases STDs Parenting Of Adolescents - From The syphilis Sexually Transmitted Diseases STDs, from your Parenting Teens Adolescents About.com Guide. http://parentingteens.about.com/cs/stds/l/blstdsyphilis.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') About Parenting of Adolescents Parenting Teens Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/7.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Parenting of Adolescents newsletter! See Online Courses Search Parenting of Adolescents Fact Sheet on Syphilis Community Join Us on the Forum Related Pages Teen Sexuality Teen Pregnancy Talk to Your Teen About Sex ... Wants to Date Parenting Library Sexually Transmitted Diseases: A Physician Tells You What You Need to Know What is syphilis? Syphilis is a complex sexually transmitted disease (STD) caused by the bacterium Treponema Pallidum. It has often been called the great imitator because so many of the signs and symptoms are indistinguishable from those of other diseases. How is syphilis spread? The syphilis bacterium is passed from person to person through direct contact with a syphilis sore. Sores mainly occur on the external genitals, vagina, anus, or in the rectum. Sores also can occur on the lips and in the mouth. Transmission of the organism occurs during vaginal, anal, or oral sex. Pregnant women with the disease can pass it to the babies they are carrying. Syphilis cannot be spread by toilet seats, door knobs, swimming pools, hot tubs, bath tubs, shared clothing, or eating utensils. What are the signs and symptoms in adults?

119. SYPHILIS Once the cause of devastating epidemics, syphilis now can be effectively controlled Although syphilis remains a significant health problem in the United http://www.idph.state.il.us/public/hb/hbsyph.htm

SYPHILIS Once the cause of devastating epidemics, syphilis now can be effectively controlled with antibiotics. Although syphilis remains a significant health problem in the United States, the number of cases reported nationally and in Illinois during 1998 was the lowest in any year since the mid 1960s. Preventing syphilis is especially important because persons infected with the disease are at increased risk for acquiring and transmitting HIV, the virus that causes AIDS. The U.S. Centers for Disease Control and Prevention, in collaboration with state and local health departments and with affected communities, is launching a national campaign to eliminate syphilis in the United States by 2005. This goal is within reach for two important reasons: the low number of reported cases in the past few years and the fact that half of all new cases in 1998 were reported in only 28 U.S. counties. Cook County, which includes Chicago and surrounding communities, was one of those counties and ranked second in the nation in 1998 in reported cases. What is syphilis?

120. Bad Blood: A Case Study Of The Tuskegee Syphilis Project - Case Study Collection Bad Blood A Case Study of the Tuskegee syphilis Project, by AW Fourtner, CR Fourtner, and CF Herreid, University at Buffalo. From the Case Study Collection http://ublib.buffalo.edu/libraries/projects/cases/blood.htm

"Bad Blood:" A Case Study of the Tuskegee Syphilis Project by A.W. Fourtner, C.R. Fourtner and C.F. Herreid University at Buffalo, State University of New York THE DISEASE Syphilis is a venereal disease spread during sexual intercourse. It can also be passed from mother to child during pregnancy. It is caused by a corkscrew-shaped bacterium called a spirochete, Treponema pallidum . This microscopic organism resides in many organs of the body but causes sores or ulcers (called chancres) to appear on the skin of the penis, vagina, mouth, and occasionally in the rectum, or on the tongue, lips, or breast. During sex the bacteria leave the sores of one person and enter the moist membranes of their partner's penis. vagina, mouth, or rectum. Once the spirochetes wiggle inside a victim, they begin to multiple at an amazing rate. (Some bacteria have a doubling rate of 30 minutes. You may want to consider how many bacteria you might have in 12 hours if one bacterium entered your body doubling at that rate.) The spirochetes then enter the lymph circulation, which carries them to nearby lymph glands that may swell in response to the infection. This first stage of the disease (called primary syphilis) lasts only a few weeks and usually causes hard red sores or ulcers to develop on the genitals of the victim, who can then pass the disease on to someone else. During this primary stage, a blood test will not reveal the disease but the bacteria can be scraped from the sores. The sores soon heal and some people may recover entirely without treatment.

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