21. Subacute Sclerosing Panencephalitis, A Measles Complication, In An subacute sclerosing panencephalitis, a Measles Complication, in an Internationally Adopted Child http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. Subacute Sclerosing Panencephalitis Surveillance -- United States subacute sclerosing panencephalitis (SSPE) is a slowvirus infection of the Further epidemiological studies of subacute sclerosing panencephalitis. http://www.cdc.gov/mmwr/preview/mmwrhtml/00001185.htm

Subacute Sclerosing Panencephalitis Surveillance United States Subacute sclerosing panencephalitis (SSPE) is a slow-virus infection of the central nervous system associated with prior measles infection. Onset generally occurs in late childhood or adolescence and is usually characterized by the insidious onset of mental deterioration and myoclonia. Although spontaneous improvement or stabilization can occur, the vast majority of patients proceed over a period of months to years to generalized convulsions, dementia, coma, and death. To collect demographic and clinical information on SSPE cases, a national SSPE registry was initiated in 1969 at the University of Tennesee. Since October 1980, responsibility for the registry has resided with the Medical College of Georgia.* The registry is supported by the Office of Biologics, Food and Drug Administration, and maintained in collaboration with CDC. *Inquiries and suspected case reports can be directed to Dr. Paul R. Dyken, Professor and Chief, Section of Pediatric Neurology, Medical College of Georgia, 1459 Laney-Walker Boulevard, Augusta GA 30912. A case of SSPE is defined by CDC as an illness with a compatible clinical course plus one of the following items of supporting laboratory evidence: 1) measles antibody detected in the cerebrospinal fluid (CSF), 2) a characteristic pattern on electroencephalography, or 3) typical histologic findings in brain biopsy material or tissue obtained on postmortem examination.

23. Early- And Late-State Subacute Sclerosing Panencephalitis Chemical Your browser does not support frames. Click here to view the unframed reprint. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

24. THE MERCK MANUAL--SECOND HOME EDITION, Subacute Sclerosing Panencephalitis In Ch subacute sclerosing panencephalitis, a progressive and usually fatal disorder, subacute sclerosing panencephalitis results from a longterm brain http://www.merck.com/mmhe/sec23/ch273/ch273l.html

var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Children's Health Issues Chapter Viral Infections Topics Introduction Central Nervous System Infections Chickenpox Erythema Infectiosum ... Rubella Subacute Sclerosing Panencephalitis Subacute Sclerosing Panencephalitis Buy The Book Print This Topic Email This Topic Pronunciations computed tomography encephalitis pneumonia roseola infantum ... subacute sclerosing panencephalitis Subacute sclerosing panencephalitis, a progressive and usually fatal disorder, is a rare complication of measles that appears months or years later and produces mental deterioration, muscle jerks, and seizures. Subacute sclerosing panencephalitis results from a long-term brain infection with the measles virus. The virus sometimes enters the brain during a measles infection. It may cause immediate symptoms of brain infection (encephalitis), or it may remain in the brain for a long time without causing problems.

25. THE MERCK MANUAL, Sec. 19, Ch. 265, Childhood Infections subacute sclerosing panencephalitis (SSPE) is also associated with measles virus and subacute sclerosing panencephalitis. A progressive, usually fatal, http://www.merck.com/mrkshared/mmanual/section19/chapter265/265b.jsp

26. Subacute Sclerosing Panencephalitis subacute sclerosing panencephalitis is a rare, progressive brain disorder causedby an abnormal immune response to the measles virus. http://www.healthatoz.com/healthatoz/Atoz/ency/subacute_sclerosing_panencephalit

27. Dr. Koop - Subacute Sclerosing Panencephalitis subacute sclerosing panencephalitis (SSPE) is a progressive, debilitating, andfatal brain disorder caused by infection with a mutant (rubeola) virus. http://www.drkoop.com/ency/93/001419.html

Home Health Reference Subacute sclerosing panencephalitis Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Subacute sclerosing panencephalitis Injury Disease Nutrition Poison ... Prevention Subacute sclerosing panencephalitis Definition: Subacute sclerosing panencephalitis (SSPE) is a progressive, debilitating, and fatal brain disorder caused by infection with a mutant measles (rubeola) virus. A mutant virus is one that has undergone genetic changes (mutations). Alternative Names: SSPE; Subacute sclerosing leukoencephalitis; Dawson´s encephalitis Causes, incidence, and risk factors: Ordinarily, the measles virus does not cause brain damage, but certain mutant forms may invade the brain, causing severe illness and death. SSPE has been reported in all parts of the world, but in western countries it is considered a rare disease. Fewer than 10 cases per year are reported in the United States, a dramatic decrease, following the nationwide measles immunization program. However, in some countries like India, over 20 cases of SSPE per million people are reported each year. SSPE tends to occur several years after an individual has measles (rubeola), even though the person seems to have fully recovered from the illness. Males are more often affected than females, and the disease generally occurs in children and adolescents.

28. AllRefer Health - Subacute Sclerosing Panencephalitis (Dawsons Encephalitis, SSP subacute sclerosing panencephalitis (Dawsons Encephalitis, SSPE, Subacute SclerosingLeukoencephalitis) information center covers causes, prevention, http://health.allrefer.com/health/subacute-sclerosing-panencephalitis-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Subacute Sclerosing Panencephalitis Subacute Sclerosing Panencephalitis Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Dawsons Encephalitis, SSPE, Subacute Sclerosing Leukoencephalitis Definition SSPE is a progressive, debilitating, and fatal brain disorder caused by infection with a mutant measles rubeola ) virus (a measles virus that has undergone certain genetic changes or mutations). Central Nervous System Measles virus usually doesn't cause brain damage, but certain mutant forms can invade the brain, causing severe illness and death. SSPE has been reported in all parts of the world, but in western countries it is considered a rare disease. Fewer than 10 cases per year are reported in the United States, decreasing the frequency of this disease dramatically, following the nationwide

29. AllRefer Health - Subacute Sclerosing Panencephalitis (Dawsons Encephalitis, SSP subacute sclerosing panencephalitis (Dawsons Encephalitis, SSPE, Subacute SclerosingLeukoencephalitis) information center covers definition, http://health.allrefer.com/health/subacute-sclerosing-panencephalitis.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Subacute Sclerosing Panencephalitis Alternate Names : Dawsons Encephalitis, SSPE, Subacute Sclerosing Leukoencephalitis Definition SSPE is a progressive, debilitating, and fatal brain disorder caused by infection with a mutant measles rubeola ) virus (a measles virus that has undergone certain genetic changes or mutations). Central Nervous System Jump to a section Definition Prevention Treatment Expectations or Prognosis ... Calling Your Health Care Provider Topics that might be of interest to you Measles Antibody Titer Cranial CT Scan EEG Other Topics Antibody Consciousness - Decreased MMR - Vaccine Muscle Cramps ... Walking/Gait Abnormalities From Our Sponsors: A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's

30. Subacute Sclerosing Pancephalitis I. subacute sclerosing panencephalitis (SSPE) 1. Clinical features. a. Onset520 years of age, predominantly in males. The disease has always been http://kobiljak.msu.edu/CAI/Pathology/CNS_Infections_F/CNS_1i.html

I. SUBACUTE SCLEROSING PANENCEPHALITIS (SSPE) Clinical features a. Onset: 5-20 years of age, predominantly in males. The disease has always been preceded by an attack of measles in the distant past or, occasionally, by measles immunization. b. Clinical presentation: personality changes, intellectual deterioration; periodic involuntary movements; decerebrate rigidity, severe dementia c. Duration: death usually in several years d. CSF changes: elevated gamma globulin; antibody titer elevated to measles Pathological changes a. Gross pathology: Cortical atrophy, demyelination and ventricular dilatation may all be present; changes are mild and are not diagnostic. b. Microscopic pathology: Inclusion bodies in oligodendroglia, neurons and astrocytes; chronic inflammatory reaction (perivascular cuffing by lymphocytes and plasma cells); some neuronal loss, gliosis and demyelination. The entire brain may be involved, but lesions are often more severe in neocortex, white matter, hippocampus, thalamus, ventral brainstem. Ultrastructural changes include paramyxovirus nucleocapsid tubules characteristic of measles virus in the inclusion bodies. This low power microscopic view shows perivascular cuffing in a case of subacute sclerosing panencephalitis, with mononuclear cells clustered around a vessel.

31. Subacute Sclerosing Panencephalitis Information Diseases Database subacute sclerosing panencephalitis,van Bogaert s sclerosing leukoencephalitis,Dawson sinclusion body encephalitis,Measles inclusion body encephalitis,SSPE http://www.diseasesdatabase.com/ddb12597.htm

Diseases Database Index Sponsors Contact ... Previous Page Subacute sclerosing panencephalitis information Search 5 synonyms or equivalents were found. Subacute sclerosing panencephalitis aka/or van Bogaert's sclerosing leukoencephalitis aka/or Dawson's inclusion body encephalitis aka/or Measles inclusion body encephalitis aka/or SSPE may be caused by or feature of (Follow link for list.) may cause or feature (Follow link for list.) belong(s) to the category of (Follow link for list.) Subacute sclerosing panencephalitis: Definition(s) via UMLS Code translations and terms via UMLS Subacute sclerosing panencephalitis: specific web sites Send Subacute sclerosing panencephalitis to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation Valid XHTML 1.0 Served 2005-09-09 20:14:29 View metadata Last major update 2005-09-03. The medical information here is presented for education, background reading and general interest. The Diseases Database is not a diagnostic or clinical decision-making tool.

32. Subacute Sclerosing Panencephalitis subacute sclerosing panencephalitis (SSPE) is a progressive neurological disordercharacterized by inflammation of the brain (encephalitis). http://www.bchealthguide.org/kbase/nord/nord185.htm

var hwPrint=1;var hwDocHWID="nord185";var hwDocTitle="Subacute Sclerosing Panencephalitis";var hwRank="1";var hwSectionHWID="nord185-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Subacute Sclerosing Panencephalitis Important It is possible that the main title of the report Subacute Sclerosing Panencephalitis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Panencephalitis, Subacute Sclerosing SSPE Dawson's Disease Dawson's Encephalitis Disorder Subdivisions None General Discussion Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder characterized by inflammation of the brain (encephalitis). The disease may develop due to reactivation of the measles virus or an inappropriate immune response to the measles virus. SSPE usually develops 2 to 10 years after the original viral attack. Initial symptoms may include memory loss, irritability, seizures, involuntary muscle movements, and/or behavioral changes, leading to neurological deterioration. Resources National Subacute Sclerosing Panencephalitis Registry PO Box 70191 Mobile, AL 36670-0191

33. MMR The Facts subacute sclerosing panencephalitis. subacute sclerosing panencephalitis (SSPE)(Adelayed complication of measles that causes brain damage and death. http://www.mmrthefacts.nhs.uk/library/subacute.php

Home Skip navigation Accessibility Information Friday September 9 2005 News Basics Library Resources ... The MMR vaccine has been linked to some serious illnesses. What are the risks to my child if I go ahead with MMR immunisation? Subacute sclerosing panencephalitis Subacute sclerosing panencephalitis (SSPE) (A delayed complication of measles that causes brain damage and death.) is a rare condition that can develop some years after natural measles infection and causes brain damage and death. People who were infected at a young age are at most risk from developing SSPE.) The average time between someone having measles to the first symptoms of SSPE is around 8 years, and death invariably follows. Since the introduction of measles vaccine in the 1960s, the numbers of people diagnosed with SSPE has decreased dramatically, and the death rate from SSPE is expected to fall even further. Measles and MMR vaccine directly protects against SSPE. Asthma Autism Crohn's disease Guillain Barre Syndrome ... Back In the MMR library... Glossary MMR and autism MMR and other countries MMR and bowel disease MMR and choice MMR and risk MMR research: overview MMR research timeline MMR video for parents Resources to print Side effects of the MMR vaccine Single vs triple vaccine The diseases Useful websites Vaccine development and testing What the experts say In this section...

34. Encephalitis – Types Of Encephalitis – Subacute-sclerosing Panencephalitis (S Types of Encephalitis – Subacutesclerosing panencephalitis (SSPE) The epidermiology of subacute sclerosing panencephalitis in England and Wales http://www.encephalitis.info/TheIllness/TypesEncephalitis/SSPE.html

Home Contact Us Links The Society ... Links to other sites L'Oiseau Bleu www.oiseaubleu.org Read the personal story of a French boy struck by SSPE Read more stories Recent Publication The epidermiology of subacute sclerosing panencephalitis in England and Wales 1990-2002 Read more . . . Subacute sclerosing panencephalitis (SSPE) is a serious viral encephalitis of children and young adults. It is a late manifestation of measles virus infection, developing usually 6 and 12 years after natural measles infection. Cases can also follow immunization with measles vaccine but at a lesser frequency than after natural measles. The annual incidence is about 1 per million. Males are more commonly affected, as are those living in rural areas. Mortality is very high. Those who survive do so with considerable intellectual and also physical impairment. The precise sequence of events that results in the development of this disease in a tiny proportion of the population is not known. The great majority of children who develop SSPE are known to have had an attack of classical measles, usually many years before. Over 50% of cases have had the disease at the unusually early age of under two years. The duration of the illness can be as short as six weeks or as long as ten years or more. Long-term survival has been reported and up to 5% may experience spontaneous long term improvement. Treatment with inosoplex (isoprinisine) may be of benefit in slowly progressive cases.

35. Subacute Sclerosing Panencephalitis (SSPE) & Vaccines The authors concluded that Subacute, Sclerosing Panencephalitis was Halsey N.Risk of subacute sclerosing panencephalitis from measles vaccination. http://www.whale.to/vaccines/sspe1.html

Diseases linked to vaccines "Stacey Berry, of Atherton, Manchester was 13 when she had a booster jab in November 1994. Days later she started having fits, "stopped smiling, and stared into space." She was diagnosed with the brain disease SSPE and given two years to live. She died in November 2000, aged 19. A post mortem examination concluded the disease was a "rare complication" of the vaccine"." Media "It is believe that the administration of Salk vaccine in N Zealand was related to the appearance of SSPE in the community. The idea that an unusual reaction to measles infection is the sole cause of SSPE is not consistent with the observations in N Zealand." SSPE AND SALK VACCINE Belgamwar RB, et al (1997). Measles, mumps, rubella vaccine induced subacute sclerosing panencephalitis. J Indian Med Assoc. 1997 Nov;95(11):594. No abstract available. PMID: 9567594; UI: 98229001. Halsey N. Risk of subacute sclerosing panencephalitis from measles vaccination. Pediatr Infect Dis J. 1990 Nov;9(11):857-8. No abstract available.PMID: 2263442; UI: 91088240. "Polymerase chain reaction detection of the hemagglutinin gene from an attenuated measles vaccine strain in the peripheral mononuclear cells of children with autoimmune hepatitis," Archives of Virology volume 141, 1996, pages 877-884: "The measles virus is known to be persistent in patients with subacute sclerosing panencephalitis (SSPE) and measles inclusion body encephalitis (MIBE). Since the introduction of measles vaccines, vaccine-associated SSPE has increased in the USA. Therefore, we should pay attention to SSPE after inoculation with measles vaccine, despite the decrease in the incidence of [wild] measles."

36. Subacute Sclerosing Panencephalitis (SSPE) : Epilepsy.com/Professionals Epilepsy and seizure diagnosis, treatment, and information for Professionals. http://professionals.epilepsy.com/page/infectious_sspe.html

Search epilepsy.com/professionals: WHO IS EPILEPSY.COM DONATE PROFESSIONAL FORUM CO-EXISTING DISORDERS ... RESOURCE LIBRARY Subacute sclerosing panencephalitis (SSPE) Co-Existing Disorders Subacute sclerosing panencephalitis (SSPE) Author: MA Goldstein and CL Harden Subacute sclerosing panencephalitis (SSPE) is a viral syndrome caused by a defective measles virus. It predominantly affects children less than 12 years of age, boys more than girls. After natural measles infection, the incidence of SSPE is 5 to 10 cases per 1 million. After vaccine, the rate is less than 1 case per 1 million vaccine recipients. Diagnosis SSPE has a gradual onset, with a full range of subtle to severe neuropsychiatric phenomena. Initial symptoms tend to be mild cognitive deficits. These can be followed by ataxia, myoclonic jerks, and seizures. The CSF profile is usually normal except for marked elevation of CSF immunoglobulin. Oligoclonal IgG bands, representing antibodies specific to measles virus, can be demonstrated. The EEG often shows widespread cortical dysfunction with a burst-suppression pattern of high-amplitude slow-wave or spike -and-slow-wave complexes occurring at a rate of every 4 to 20 seconds. These may be synchronous with or independent of myoclonic jerks.

37. Subacute Sclerosing Panencephalitis subacute sclerosing panencephalitis (SSPE) is a progressive neurological disordercharacterized by inflammation http://my.webmd.com/hw/brain_nervous_system/nord185.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Subacute Sclerosing Panencephalitis Important It is possible that the main title of the report Subacute Sclerosing Panencephalitis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Panencephalitis, Subacute Sclerosing SSPE Dawson's Disease Dawson's Encephalitis Disorder Subdivisions None General Discussion Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder characterized by inflammation of the brain (encephalitis). The disease may develop due to reactivation of the measles virus or an inappropriate immune response to the measles virus. SSPE usually develops 2 to 10 years after the original viral attack. Initial symptoms may include memory loss, irritability, seizures, involuntary muscle movements, and/or behavioral changes, leading to neurological deterioration. Resources National Subacute Sclerosing Panencephalitis Registry PO Box 70191 Mobile, AL 36670-0191

38. Subacute Sclerosing Panencephalitis - YourDictionary.com - American Heritage Dic Search Mamma.com for subacute sclerosing panencephalitis . TYPE IN YOUR WORD CLICK GO! Search. Normal, Definitions, Short defs http://www.yourdictionary.com/ahd/s/s0833050.html

Search Mamma.com for "subacute sclerosing panencephalitis" Search: Normal Definitions Short defs (Pronunciation Key) subacute scle·ros·ing panencephalitis Listen: skl -r s ng n. An often fatal degenerative disease of the central nervous system occurring chiefly in young people, caused by slow infection with a measles virus and characterized by progressive loss of mental and motor functions ending in dementia and paralysis. sclerosing , from sclerose to harden , back-formation from sclerosed Back to Search Back The American Heritage Dictionary of the English Language, Fourth Edition

39. Subacute Sclerosing Panencephalitis In The Differential Diagnosis Of Encephaliti The authors describe five cases of subacute sclerosing panencephalitis subacute sclerosing panencephalitis A preventable disease that needs to be http://www.neurology.org/cgi/content/abstract/63/8/1489

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text Full Text (PDF) Take the CME quiz ... Alert me if a correction is posted Services Email this article to a friend Related articles in Neurology Similar articles in this journal Similar articles in PubMed ... Cited by other online articles PubMed PubMed Citation Articles by Honarmand, S. Articles by Bellini, W. J. Related Collections Viral infections Oscillopsia NEUROLOGY 2004;63:1489-1493 American Academy of Neurology Brief Communications Subacute sclerosing panencephalitis in the differential diagnosis of encephalitis S. Honarmand, MS C. A. Glaser, DVM MD E. Chow, MD J. J. Sejvar, MD C. P. Preas, BA G. C. Cosentino, BS H. T. Hutchison, MD PhD and W. J. Bellini, PhD Address correspondence and reprint requests to Somayeh Honarmand, Viral and Rickettsial Disease Laboratory, California Department of Health Services, 850 Marina Bay Parkway, Richmond, CA 94804; e-mail: The authors describe five cases of subacute sclerosing panencephalitis (SSPE) identified through the California Encephalitis Project that emphasize the importance of considering SSPE in the differential diagnosis of encephalitis, particularly among pediatric patients.

40. Neurology -- Sign In Page subacute sclerosing panencephalitis in the differential diagnosis of encephalitis . A continuing high incidence of subacute sclerosing panencephalitis http://www.neurology.org/cgi/content/full/63/8/1352

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Neurology Online. Full Text Subacute sclerosing panencephalitis: A preventable disease that needs to be prevented Bale Neurology. This Article Full Text (PDF) Correspondence: Submit a response ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Bale, J. F., Jr. Related Collections Encephalitis Viral infections To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$20.00 Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

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