81. Stiff Person Syndrome Health and Nutrition from a Christian perspective. http://www.fitnessforoneandall.com/difficulties/subject/stiff_person.htm

Fitness for One and All Home Page Dealing with Health Difficulties Stiff Person Syndrome Stiff Person Syndrome: Part One Stiff Person Syndrome: Part Two Stiff Person Syndrome: Part Three Stiff Person Syndrome: Part Four ... Fitness for One and All Home Page www.FitnessforOneandAll.com/difficulties/subject/stiff_person.htm

82. Stiff Person Syndrome Sites Web sites devoted to health, nutrition, and fitness. http://www.fitnessforoneandall.com/links/health/stiff_person.htm

Fitness for One and All Home Page Stiff Person Syndrome Sites Fitness for One and All's Stiff Person Syndrome pages Most of the links below are direct links to pages on stiff person syndrome (SPS, a.k.a. stiff man syndrome) on the indicated Web sites. There are few entire Web sties devoted to this rare disorder. - By the American Academy of Physical Medicine and Rehabilitation. BrainTalk Communities - A forum on stiff person syndrome. Medical Library Stiff Person Syndrome - From a holistic/ natural health oriented Web site. NINDS Stiff-Person Syndrome Information Page - by the National Institute of Neurological Disorders and Stroke. NORD - Stiff Person Syndrome - By National Organization for Rare Disorders, Inc. OMIM Stiff Man Syndrome - On the Online Mendelian Inheritance in Man database. Stiff Man Syndrome Neurological Home Page - By Yale University. Contains one of the best descriptions of SPS I have found, along with a SPS Roundtable Prednisone Prednisone is one of the more commonly prescribed drugs for SPS. The pages below provide info on this drug. ADAP drugs: Prednisone - By The Access Project.

83. Clinical Trial: Rituximab To Treat Stiff Person Syndrome Stiff Person syndrome with elevated antiGAD antibody titers. The stiff-personsyndrome an autoimmune disorder affecting neurotransmission of http://www.clinicaltrials.gov/ct/show/NCT00091897

Home Search Browse Resources ... About Rituximab to Treat Stiff Person Syndrome This study is currently recruiting patients. Verified by National Institutes of Health Clinical Center (CC) August 22, 2005 Sponsored by: National Institute of Neurological Disorders and Stroke (NINDS) Information provided by: National Institutes of Health Clinical Center (CC) ClinicalTrials.gov Identifier: Purpose This study will test whether rituximab (RITUXAN (Trademark)) can relieve symptoms of stiff person syndrome (SPS), a progressive disease that causes stiffness of the muscles and muscle spasms induced by unexpected noises, touches, or stressful events. People with SPS may have certain proteins in their blood called anti-GAD antibodies that may cause some of the symptoms of the disease. Rituximab, a drug approved to treat lymphomas, targets certain white blood cells that produce antibodies. This study will see if rituximab can also be effective in patients with SPS who have high anti-GAD antibodies. Patients between 25 and 80 years of age with SPS may be eligible for this study. Candidates are screened with a medical history, physical examination, and blood tests. Participants undergo the following tests and procedures:

84. Neurology -- Collected Resources : Stiff Person Syndrome Stiff person syndrome does not always occur with maternal passive transfer of Paraneoplastic stiff person syndrome with metastatic adenocarcinoma and http://www.neurology.org/cgi/collection/stiff_person_syndrome

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH RESULT QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Stiff person syndrome Citations 1-10 of 10 total displayed. Most recent content (14 Jun 2005): BRIEF COMMUNICATIONS A neuropsychological assessment of phobias in patients with stiff person syndrome Rezvan Ameli, Joseph Snow, Goran Rakocevic, and Marinos C. Dalakas Neurology 2005; 64: 1961-1963. [Abstract] [Full text] [PDF] Past content (since Aug 2002): EDITORIALS GAD antibodies in stiff-person syndrome Thashi Chang and Bethan Lang Neurology 2004; 63: 1999-2000. [Full text] [PDF] BRIEF COMMUNICATIONS Markedly elevated GAD antibodies in SPS: Effects of age and illness duration B. B. Murinson, M. Butler, K. Marfurt, S. Gleason, P. De Camilli, and M. Solimena Neurology 2004; 63: 2146-2148. [Abstract] [Full text] [PDF] BRIEF COMMUNICATIONS Stiff person syndrome does not always occur with maternal passive transfer of GAD65 antibodies R. Nemni, L. M. Caniatti, M. Gironi, E. Bazzigaluppi, and D. De Grandis

85. Stiff Person Syndrome Stiff person syndrome is an extremely rare neurological disorder characterizedby progressive muscle http://my.webmd.com/hw/health_guide_atoz/nord326.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Medical Library Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... For a Complete Report Stiff Person Syndrome Important It is possible that the main title of the report Stiff Person Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Moersch-Woltmann Syndrome Muscular Rigidity - Progressive Spasm SMS Stiff Man Syndrome Disorder Subdivisions None General Discussion Stiff-person syndrome is an extremely rare neurological disorder characterized by progressive muscle stiffness (rigidity) and spasms. It usually begins in young adults, first involving muscles of the trunk and progressing to affect muscles of the legs. This syndrome may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact. Those affected have a characteristic stiff-legged way of walking (gait) and increase in the curvature of the spine (lordotic posture). The exact cause of stiff person syndrome is not known. Resources American Autoimmune Related Diseases Association, Inc.

86. Diagnose-Me: Stiff Person Syndrome The Analyst (TM) Comprehensive Online Evaluations For Those Seeking Answers ToTheir Health Problems. Travel-Free Results, Now! http://www.diagnose-me.com/glossary/G1654.html

Home FAQ Start The Analyst Glossary: Stiff Person Syndrome Definition Stiff Person Syndrome (SPS) is a rare, progressive neuromuscular condition in which a hyperactive startle reflex results in constant painful contraction of the muscles, thus causing violent spasms of the voluntary muscles, particularly the muscles of the back and upper legs. These spasms are capable of slamming the victim into walls and furniture. The disorder's cause is unknown. Also: Moersch-Woltmann Syndrome, Stiff Man Syndrome Topics Related To Stiff Person Syndrome Stiff Man Syndrome The Condition Stiff Man Syndrome , also known as Moersch-Woltmann Syndrome or Stiff Person Syndrome or SPS, is a neuromuscular condition in which a hyperactive startle reflex results in the contraction of the..." Last updated: Jun 14, 2005 Home FAQ Start The Analyst Design by: RoyalWebHosting.com

87. The Bioline EPrints Archive - Stiff Person Syndrome And Myasthenia Gra Association of stiff person syndrome, an immune related disorder of anterior horncells and Keywords, Stiff person syndrome, Myasthenia gravis ni02026 http://bioline.utsc.utoronto.ca/archive/00000356/

@import url(http://bioline.utsc.utoronto.ca/eprints.css); @import url(http://bioline.utsc.utoronto.ca/eprints.css); @import url(http://bioline.utsc.utoronto.ca/print.css); The Bioline EPrints Archive Home About Browse Search ... Help Stiff Person Syndrome and Myasthenia Gra Saravanan, P.K. and Paul, J. and Sayeed, Zaheer Ahmed Stiff Person Syndrome and Myasthenia Gra Neurology India pp. 98-99 Full text available as: PDF - Requires Adobe Acrobat Reader or other PDF viewer. Abstract Association of stiff person syndrome, an immune related disorder of anterior horn cells and myasthenia gravis an endplate disorder with similar pathogenesis, is rare. This communication documents this association in the Indian literature for the first time. Item Type: Journal (Paginated) Keywords: Stiff person syndrome, Myasthenia gravis ni02026 Subjects: Medicine Neurology ID Code: Deposited By: Sun, Yibing Deposited On: 12 June 2003 Alternative Locations: http://www.bioline.org.br/abstract?ni02026 http://www.neurologyindia.com/vol50-1/FullArticles/shortreport04.pdf Repository Contact Information © 2005 Bioline International

88. Stiff Person Syndrome And Myasthenia Gravis. Saravanan PK, Paul J, Sayeed Zaheer Neurol India is an peerreviewed biomedical periodical of Neurological Societyof India. http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2002;volume=50;iss

89. Stiff Person Syndrome And Myasthenia Gravis., Saravanan PK, Paul J, Sayeed Zahee Neurol India is an peerreviewed biomedical periodical of Neurological Societyof India. http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2002;volume=50;iss

90. NORD - National Organization For Rare Disorders, Inc. Dramatic Results Reported in Stiff Person syndrome Study The incidence ofStiff Person syndrome (formerly known as Stiffman s Disease) has been http://www.rarediseases.org/news/stiff

Database Subscriptions Many libraries, schools, universities, and hospitals subscribe to NORD's Rare Disease Database for unlimited access to reports on more than 1,150 diseases. Index of Rare Diseases This is the list of diseases currently covered in the Rare Disease Database. Rare Disease Database Search this database for reports on more than 1,150 diseases. View sample report Index of Organizations This is the list of organizations in NORD's Organizational Database. Organizational Database Read about more than 2,000 patient organizations and other sources of help. NORD's Washington Office Check here to read about events on Capitol Hill, funding for rare-disease research, and other topics of interest from NORD's office in Washington, DC. News Briefs Dramatic Results Reported in Stiff Person Syndrome Study On Dec. 27, 2001, The New England Journal of Medicine reported that intravenous immunoglobulin (IVIg) has brought dramatic relief from symptoms to patients with the rare disorder known as Stiff Person Syndrome (SPS). The authors believe their research supports the theory that SPS results from an autoimmune response gone awry in the brain and spinal cord of the person with this ailment. SPS is an extremely rare neurological disorder characterized by progressive stiffness and spasms of certain muscles in the trunk and limbs. It sometimes begins with intermittent episodes, often precipitated by surprise or minor physical contact. The incidence of Stiff Person Syndrome (formerly known as Stiffman's Disease) has been estimated at one in a million.

91. NORD - National Organization For Rare Disorders, Inc. National Organization for Rare Disorders is dedicated to helping people withrare, orphan diseases. Rarediseases.org contains information on the prevention, http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Stiff Person

92. Treatment Of Stiff Person Syndrome With Rituximab - Neurological Journal Update Treatment of stiff person syndrome with rituximab. 7/25/2005 Journal Journal ofNeurology Citation Journal of Neurology Neurosurgery and Psychiatry 2005 http://www.medcompare.com/litupdate.asp?ArticleID=6757

93. Hill Health Topics A-Z - Stiff Person Syndrome Stiff Person syndrome. National Organization for Rare Disorders. Important It ispossible that the main title of the report Stiff Person syndrome is not the http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord326&SE

94. BrainTalk Communities - Anyone Know The Prognosis For Stiff Person Syndrome Smile anyone know the prognosis for stiff person syndrome. i have been diagnosedwith stiff person syndrome and am trying to find out about it and the http://brain.hastypastry.net/forums/showthread.php?t=41831

95. BrainTalk Communities - Trying To Find Others With Stiff Person Syndrome i have been diagnosed with stiff person syndrome and am trying to contact otherswith sps and to find out info especially long term prognosis, http://brain.hastypastry.net/forums/showthread.php?t=43955

96. Immunotherapy Treatment Shows Dramatic Results For Rare Neurological Disorder: S intravenous immunoglobulin (IVIg), administered to patients suffering fromstiff person syndrome (SPS), provides dramatic relief from disabling symptoms http://www.docguide.com/dg.nsf/PrintPrint/6D1B23434D3DB53285256B2F005F0E66

To print: Select File and then Print from your browser's menu Title: Immunotherapy Treatment Shows Dramatic Results For Rare Neurological Disorder: Stiff Person Syndrome URL: http://www.pslgroup.com/dg/210DAE.htm Doctor's Guide December 27, 2001 BETHESDA, MD December 27, 2001 An immunologic therapy, intravenous immunoglobulin (IVIg), administered to patients suffering from stiff person syndrome (SPS), provides dramatic relief from disabling symptoms, according to a study appearing in the December 27, 2001, issue of The New England Journal of Medicine . The study's principal author, Marinos C. Dalakas, M.D., chief of the Neuromuscular Diseases Section of the National Institute of Neurological Disorders and Stroke, says that the success of the treatment supports the theory that SPS is the result of an autoimmune response gone awry in the brain and spinal cord. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise, touch, and emotional distress that can set off muscular spasms. People with SPS are often too disabled to walk or move, or are afraid to leave the house because of stimuli-triggered spasms and frequent falls. The incidence of SPS has been estimated at one in every one million persons, but according to Dr. Dalakas, "the disorder is so often misdiagnosed as Parkinson's disease, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia that its actual incidence is probably much higher."

97. AAPM&R - Case No. 47, Cont Onset of stiff person syndrome is generally in the fourth or fifth decades Diagnostic criteria for stiff person syndrome include (1) insidious onset of http://www.aapmr.org/education/archive/emg0010e.htm

Search Entire Site Member Center PASSOR Practice Issues Legislative/Business/Clinical Annual Assembly Medical Education Industry Opportunities What is a Physiatrist? Legislative, Business and Clinical Practice Issues Annual Assembly Medical Education ... EMG EMG Case No. 47, October 2000, continued Diagnostic Impression The presence of continuous motor unit activity associated with this individual's clinical history of muscles twitching involving predominantly the abdominal muscles and her history of insulin dependent diabetes mellitus is suggestive of stiff person syndrome. What other diagnostic procedures (laboratory tests, etc.), if any, are needed? What treatment would you recommend? Commentary V Stiff person syndrome is characterized by slowly progressive increasing stiffness affecting the axial musculature, predominantly the paraspinal and abdominal muscles as well as the lower and upper limbs. On rare occasion symptoms may be confined to a limb or an upper or lower extremity. Over time there is an increasing frequency in the rate of muscle spasms. Some attacks of muscle spasms are so severe that individual may be thrown to the floor. Attacks may be triggered by alterations in emotion, startle, and loud noises. Severe cases may have marked contraction of the hip and knee extensors, ankle dorsiflexors, and abdominal and paraspinal muscles. In advanced cases contraction of the paraspinal, abdominal and intercostals muscles may be seen. Hyperlordosis of the lumbosacral spine is common secondary to lumbosacral paraspinal muscles contraction, as is hunching of the shoulders secondary to cervical paraspinal hypertrophy.

98. AAPM&R - Case No. 47, Cont Stiff person syndrome involves the abdominal muscles and is frequently associated Individuals with stiff person syndrome tend to have a marked startle http://www.aapmr.org/education/archive/emg0010b.htm

Search Entire Site Member Center PASSOR Practice Issues Legislative/Business/Clinical Annual Assembly Medical Education Industry Opportunities What is a Physiatrist? Legislative, Business and Clinical Practice Issues Annual Assembly Medical Education ... EMG EMG Case No. 47, October 2000, continued History A 22-year-old woman with a 4-year history of insulin dependent diabetes mellitus and hypothyroidism presents to the electrodiagnostic laboratory with a chief complaint of involuntary muscle tightening and spasms. She has not experienced pain in association with the spasms, and she has no muscle cramps. She denies weakness. Her symptoms began 8 years ago while she was in high school, and the muscle tightening and spasms have been slowly progressive in severity and duration. The episodic tightening or twitching of her muscles involves her abdominal, hand, and lower limb muscles bilaterally. These paroxysmal episodes last for approximately 5 seconds and occur many times during the day. On occasion, she notices that objects fall from her hands. She believes that cold may induce her symptoms. Initially, she was not concerned about the abdominal spasms since they helped maintain her muscle tone. Prior to continuing, please develop a differential diagnosis and list each possible diagnosis in order of likelihood.

99. Stiffman Syndrome Also known as Stiff Person syndrome or MoerschWoltman. A rare, progressiveneurological disease with symptoms of severe spasm, rigidity and falls. http://www.stiffman.org/

Also known as: Stiff Person Syndrome Moersch-Woltman Stiff-person syndrome is an extremely rare neurological disorder characterized by progressive muscle stiffness (rigidity) and spasms. It usually begins in young adults, first involving muscles of the trunk and progressing to affect muscles of the legs. This syndrome may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact. Those affected have a characteristic stiff-legged way of walking (gait) and increase in the curvature of the spine (lordotic posture). The exact cause of stiff person syndrome is not known. NORD - National Organization for Rare Disorders I was diagnosed with Stiffman Syndrome in 1994. May you find answers along with the whisper of hope. Welcome. Please click to enter website. It is difficult to say what is impossible, for the dream of yesterday is the hope of today and the reality of tomorrow. ~ Robert H. Goddard ~

100. Stiff Person Syndrome Synonyms, Eastern Carolina Stiff Person syndrome Synonyms University Health Systems of Eastern Carolinaserves tarboro, ahoskie, edento, winsor, maxhead, dear county, http://www.uhseast.com/114295.cfm

Health News Health Library Health Topics Healthy Living ... Nutrition Information on diseases and health concerns, including symptoms, treatment options, and prevention. Stiff Person Syndrome Synonyms Disorder Subdivisions General Discussion Resources ... For a Complete Report Important It is possible that the main title of the report Stiff Person Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Moersch-Woltmann Syndrome Muscular Rigidity - Progressive Spasm SMS Stiff Man Syndrome Disorder Subdivisions None General Discussion Stiff-person syndrome is an extremely rare neurological disorder characterized by progressive muscle stiffness (rigidity) and spasms. It usually begins in young adults, first involving muscles of the trunk and progressing to affect muscles of the legs. This syndrome may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact. Those affected have a characteristic stiff-legged way of walking (gait) and increase in the curvature of the spine (lordotic posture). The exact cause of stiff person syndrome is not known. Resources American Autoimmune Related Diseases Association, Inc.

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