61. Karger Publishers A diagnosis of recurring stevensjohnson syndrome was made. To our knowledge,we report the first case of stevens-johnson syndrome associated with http://content.karger.com/ProdukteDB/produkte.asp?Doi=18500

62. Lamictal & Stevens-johnson Syndrome I m afraid of stevensjohnson syndrome. I ma 40 year old female. Intial dosewould be 25MG twice a day. Is it worth the risk? THanks. Dear Ms. R http://www.bipolarworld.net/Phelps/ph_2002/ph727.htm

Home Bipolar Disorder News WebSite News Bipolar Disorder ... Contact Us My doctor wants me to try Lamictal. I'm afraid of Stevens-johnson syndrome. I'm a 40 year old female. Intial dose would be 25MG twice a day. Is it worth the risk? THanks Dear Ms. R' In my experience, once I started using one quarter of that dose as the starting place (instead of the dose you cite, although that's what's in the manufacturer's info (or was; they are probably onto this by now, as most of my colleagues seem to have arrived at the same conclusion)) after that, I haven't seen hardly a single case of rash if my patient actually followed the instructions for ultra-slow dose increases. And I understand that some leading figures on this topic, like Dr. Laura Marangell (per a recent conference presentation) are now so comfortable with the rash risk that they don't even stop the medication if a person gets a bumpy, red, itchy spot on their body only if it's around the mouth or inside; if there are blood test changes; or if a person is feeling sick as well as having the rash. Otherwise, they just pull back on the dose for a bit and wait for the rash to go away. In other words, the risk of S-J syndrome is much lower now that we're using much slower dose increases. I saw 1/3,000 for the severe rash frequency recently, down from 1/1,000, for example. That doesn't make it less scary, perhaps, but it at least is less common than it was when we started this. Check out the

63. Stevens-Johnson Syndrome : Sites Et Documents Francophones syndrome . http://www.chu-rouen.fr/ssf/pathol/stevensjohnsonsyndrome.html

Stevens-Johnson syndrome Synonyme(s) CISMeF Stevens-Johnson syndrome. Synonyme(s) MeSH Ectodermose érosive pluriorificielle ; Fiessinger-Rendu, syndrome Arborescence(s) Stevens-Johnson syndrome Stevens-Johnson syndrome maladies de la peau et du tissu conjonctif maladies de l'appareil stomatognathique Position du mot-clé dans l' (les) arborescence(s) : Vous pouvez consulter toutes les ressources ou seulement les principales ou utiliser l' outil de recherche les recommandations les documents concernant l' enseignement les documents destinés aux patients Ou consulter ci-dessous une sélection des principales ressources : enseignement et éducation Iatrogénie. Diagnostic et prévention - Toxidermies médicamenteuses - - Examen Classant National : Question(s) 181 Module(s) 11 - [Par Dr Roujeau JC (Hôpital Henri Mondor de Créteil), Dr Bonnetblanc JM, Dr Schmutz JL, et-al. . Site éditeur Université Louis Pasteur de Strasbourg (ULP), Faculté de Médecine accès par Tours ; visité le : 14/01/2003]. mots clés : dermatologie /enseignement et éducation diagnostic différentiel indice de gravité *Lyell, syndrome ... toxidermies /étiologie type : *cours *image 12 août 2005 courriel Menu général CISMeF Haut de page © CHU de Rouen . Toute utilisation partielle ou totale de ce document doit mentionner la source.

64. Stevens-Johnson Syndrome Information Diseases Database stevensjohnson syndrome,Toxic epidermal necrolysis,Erythema multiforme,Lyell sdisease,Scalded skin syndrome, Disease Database Information. http://www.diseasesdatabase.com/ddb4450.htm

Diseases Database Index Sponsors Contact ... Previous Page Stevens-Johnson syndrome information Search 5 synonyms or equivalents were found. Stevens-Johnson syndrome aka/or Toxic epidermal necrolysis aka/or Erythema multiforme aka/or Lyell disease aka/or Scalded skin syndrome may be caused by or feature of (Follow link for list.) may cause or feature (Follow link for list.) belong(s) to the category of (Follow link for list.) Stevens-Johnson syndrome: Definition(s) via UMLS Code translations and terms via UMLS Stevens-Johnson syndrome: specific web sites Send Stevens-Johnson syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation Valid XHTML 1.0 Served 2005-09-09 19:51:36 View metadata Last major update 2005-09-03. The medical information here is presented for education, background reading and general interest. The Diseases Database is not a diagnostic or clinical decision-making tool. Please consult your own licensed physician regarding diagnosis and treatment of any medical condition!

65. Health Information | Health & Safety Resources | Child Health & Safety | Childre SJS, or stevensjohnson syndrome, is an abrupt, severe injury to the mouth, eyes,and skin, where large sheets of mucosa or skin are destroyed and then shed http://www.pediatricweb.com/seattle/article.asp?ArticleID=849&ArticleType=9

66. Arch Dermatol -- Abstract: Toxic Epidermal Necrolysis And Stevens-Johnson Syndro FULL TEXT. Recurrent Erythema Multiforme/stevensjohnson syndrome Response toMycophenolate Mofetil Davis et al. Arch Dermatol 2002;1381547-1550. http://archderm.ama-assn.org/cgi/content/abstract/136/3/323

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 136 No. 3, March 2000 Featured Link E-mail Alerts Study Article Options Full text PDF Send to a Friend Readers Reply Submit a reply Related articles in this issue Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Garcia-Doval I Roujeau JC Articles that cite this article ISI Web of Science (54) ... Contact me when this article is cited Topic Collections Dermatology, Other Topic Collection Alerts Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome Does Early Withdrawal of Causative Drugs Decrease the Risk of Death? Ignacio Garcia-Doval, MD Laurence LeCleach, MD Xose-Luis Otero, PhD Jean-Claude Roujeau, MD Arch Dermatol. Withdrawal of the drug(s) that cause severe cutaneous adverse reactions is usually recommended without proof that it alters the course of those reactions.

67. Arch Dermatol -- Abstract: Stevens-Johnson Syndrome Associated With Mycoplasma P The stevensjohnson syndrome is a multisystem inflammatory disorder associatedwith a widespread erythematous eruption that can result in death. http://archderm.ama-assn.org/cgi/content/abstract/114/2/241

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 114 No. 2, February 1978 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Sontheimer RD Krueger GG Articles that cite this article Contact me when this article is cited Stevens-Johnson syndrome associated with Mycoplasma pneumoniae infections R. D. Sontheimer, R. A. Garibaldi and G. G. Krueger The Stevens-Johnson syndrome is a multisystem inflammatory disorder associated with a widespread erythematous eruption that can result in death. Although usually considered a pediatric disease, this syndrome frequently affects adults. There are many etiologic associations including drugs and infections; however, the pathophysiology of the syndrome remains

68. Arava Cases In Pennsylvania - Bextra, Stevens-Johnson Syndrome - Handler, Hennin Those injured by Bextra or Arava in Pennsylvania can rely on the attorneys atHandler, Henning Rosenberg for help with the legal issues surrounding their http://www.hhrlaw.com/drugandmedicalinjuries/case_stevens_johnson_syndrome.html

SJS Linked To Trileptal, Bextra and Arava Stevens-Johnson Syndrome - SJS Trileptal Overview A growing number of patients are experienceing and reporting severe side effects from their use of Trileptal. Trileptal is manufactured by Novartis Pharmaceuticals Inc. This medicine is an anticonvulsant used to prevent and treat seizures. It may also be used to treat other conditions as determined by your doctor. Life-altering outcomes have become more common for those using Trileptal. FDA Takes Action The FDA notified healthcare professionals about revisions to the warnings and precautions sections of the prescribing information for Trileptal(oxcarbazepine) tablets and oral suspension, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults and children ages 4-16 years with epilepsy. The updated warnings section describes serious dermatological reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) that have been reported in both children and adults in association with Trileptal use. The PRECAUTIONS section has been updated to include language regarding multi-organ hypersensitivity reactions that have been reported in association with Trileptal use. Bextra Bextra is commonly used for the treatment of osteoarthritis, rheumatoid arthritis and dysmenorrhea (menstrual pain). Pharmacia, the manufacturer of Bextra has reported to the Food and Drug Administration that life-threatening skin and hypersensitivity reactions can occur with the use of the drug. These conditions appear in the form of inflammation of the mucous membranes of the mouth, throat, genitals, intestinal tract, and membrane lining the eyelids. This inflammation can lead to lesions and blisters causing intense pain and even death from infection.

69. View Article The stevensjohnson syndrome typically begin with a non-specific upper respiratory Outbreak of stevens-johnson syndrome/toxic epidermal necrolysis http://www.pchrd.dost.gov.ph/e-Health/article/view_article.php?type=feature&id=2

70. Log In Problems Like a bad case of poison ivy that can get past the skin to the uvea, liver,kidneys, and mucous membranes of the GI tract, stevensjohnson syndrome (SJS) http://www.medscape.com/viewarticle/408712

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71. Log In Problems Read about a potential solution for the limited and controversial treatment ofan acute mucocutaneous disorder associated with considerable morbidity. http://www.medscape.com/viewarticle/410743

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72. Abc11tv.com: Stevens-Johnson Syndrome The little girl was diagnosed with stevensjohnson syndrome. Stevens-JohnsonSyndrome can cause blindness and is deadly nearly a third of the time. http://abclocal.go.com/wtvd/story?section=eye_on_health&id=3241839

73. MPS Singapore - South East Asia Casebook 2004 (4) - November - Stevens-Johnson S A dermatologist diagnosed stevensjohnson syndrome complicated by toxic epidermal See Rzany B et al. ‘Risk of stevens-johnson syndrome and Toxic http://www.medicalprotection.org/medical/singapore/publications/casebook/2004_4_

Choose a Country / Region Please select... Global Hong Kong Ireland Malaysia New Zealand Singapore South Africa United Kingdom Search: Site Map You are in: Medical Singapore Publications Casebook Stevens-Johnson syndrome Ms G was in her twenties when she suffered blackouts. Her GP, Dr A, referred her to Dr P, a consultant neurologist. Ms G was diagnosed as suffering from epilepsy and treated with phenytoin at a dose of 300mg daily. Shortly after this Ms G felt very tired and unwell. Her father claimed to have spoken to Dr C, another practice member, about her. No notes were kept of the advice given. Ms G continued on the phenytoin. The next day Ms G saw Dr C. She claimed to have reported feeling very unwell, drowsy and slow. No record of these complaints was found in the notes. Dr C advised Ms G to continue the phenytoin, with a blood test after two weeks on the drug, as recommended by Dr P. PDF of this edition's case reports Over the next week, both Ms G and her father attended the surgery and spoke to Dr C about her symptoms of drowsiness. At some point Ms G went for a phenytoin blood level at hospital. The notes are confusing and there is no record of when exactly the blood test was performed, or when any result was received. Two weeks after starting the phenytoin Ms G saw Dr V at the practice. Ms G had flu-like symptoms and was covered in a maculo-papular rash. Dr V asked Drs C and A to look at it.

74. Stevens-Johnson Syndrome - Bextra Bextra has been linked to heart attack, stroke, stevensjohnson syndrome, StevenJohnson. http://www.wrongful-death.com/wrongful_death_lawyer/Stevens-Johnson-syndrome.htm

Choose a Destination Home Page Practice Areas (Main Page) Wrongful Death Lawyers Free Online Consultation Legal Research Legal Resources Referral Policy Contact Us Auto Accidents Auto Accident Lawyer Car Accidents Aviation Accidents ... Zicam Loss of Taste If you would like to receive information regarding potential new lawsuits, class actions, lawsuit settlements and large verdicts, please enter your name and email address below, and press "submit" Your Name: Your Email Address: Stevens Johnson Syndrome Stevens-Johnson syndrome affects the mucous membranes of the mouth, eyes nostril and both the genital and anal regions. The syndrome may result in leasions on other areas of the body. Oropharyngeal (mouth) lesions are sometimes so severe that they prevent eating. Often, the skin lesions have three different colorations and the lesion eventually turns into a blister. Conjuctivitis may result in the eye, leading to severe mucous build up and ending in corneal scarring. Patients also develop pulmonary difficulties that result in pneumonia. If you or a loved one are suffering from any of the symptoms described above you may be entitled to monetary compensation. Complete the free consulation form below and an attorney may contact you to disuss your claim.

75. Bextra Heart Attack, Stroke, Stevens-Johnson Syndrome, Toxic Epidermal Necrolysi bextra Linked to Heart Attack, stroke, stevensjohnson syndrome, toxic epidermalnecrolysis, exfoliative dermatitis and erythema multiforme. http://www.wrongful-death.com/wrongful_death_lawyer/Bextra.html

Choose a Destination Home Page Practice Areas (Main Page) Wrongful Death Lawyers Free Online Consultation Legal Research Legal Resources Referral Policy Contact Us Auto Accidents Auto Accident Lawyer Car Accidents Aviation Accidents ... Zicam Loss of Taste If you would like to receive information regarding potential new lawsuits, class actions, lawsuit settlements and large verdicts, please enter your name and email address below, and press "submit" Your Name: Your Email Address: Bextra Heart Attack Since BEXTRA was approved by the FDA on November 16,2001,in postmarketing experience,rare spontaneous reports of hypersensitivity reactions (i.e., anaphylactic reactions and angioedema) and skin reactions, including cases of Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis and erythema multiforme, have been received for patients treated with BEXTRA. These cases, some of which were serious/life threatening,have occurred in patients with and without a history of allergic-type reactions to sulfonamides. WARNINGS -Anaphylactoid Reactions: In postmarketing experience, cases of hypersensitivity reactions (anaphylactic reactions and angioedema) have been reported in patients receiving BEXTRA (see ADVERSE REACTIONS-Postmarketing Experience). These cases have occurred in patients with and without a history of allergic-type reactions to sulfonamides (see CONTRAINDICATIONS).

76. Stevens-Johnson Syndrome - Enpsychlopedia stevensjohnson syndrome (SJS) is a severe and potentially life-threatening (15% It uses material from the Wikipedia article stevens-johnson syndrome . http://psychcentral.com/psypsych/Stevens-Johnson_syndrome

home resource directory disorders quizzes ... support forums Stevens-Johnson syndrome Stevens-Johnson syndrome (SJS) is a severe and potentially life-threatening (15% of cases) disease , it is a hypersensitivity complex affecting the skin and the mucous membranes , a severe expression of erythema multiforme (EM) (and so SJS is also called erythema multiforme major SJS is characterized by fever, sore throat, and headache leading to the sudden development of circular mucocutaneous lesions that can cover the majority of the skin. These lesions begin as macules and can develop into papules vesicles bullae , or urticarial plaques. The most extreme cases are termed Toxic Epidermal Necrolysis Syndrome (TENS) or Lyell's Syndrome , in these cases the entire skin is affected. Treatment is initially similar to that of patients with thermal burns, and continued care can only be supportive and symptomatic, there is no specific drug treatment (2002). The cause of SJS is either infections (usually following viral infections such as herpes simplex virus influenza mumps cat-scratch fever ... Epstein-Barr virus , or similar), drug-induced ( valdecoxib penicillins barbiturate sulfas ... nevirapine ), malignancy-related (

77. Oral Chloroquine-induced Stevens-Johnson Syndrome Beedimani RS, Rambhimaiah S - The Indian Journal of Pharmacology is an official organ of the Indian PharmacologicalSociety. http://www.ijp-online.com/article.asp?issn=0253-7613;year=2004;volume=36;issue=2

78. Stevens-Johnson Syndrome And Drugs stevensjohnson syndrome after sertraline. Acta Derm Venereol. Fatal Stevens-Johnsonsyndrome in an AIDS patient treated with sulfadiazine. http://www.whale.to/drugs/Stevens_Johnson_syndrome.html

Stevens-Johnson syndrome and drugs Srivastava M, et al. Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. Gastroenterology. 1998 Sep;115(3):743-6. PMID: 9721172; UI: 98387853. [See Related Articles] Jan V, et al. Stevens-Johnson syndrome after sertraline. Acta Derm Venereol. 1999 Sep;79(5):401. No abstract available.PMID: 10494732; UI: 99422923. [See Related Articles] Carrion-Carrion C, et al. Fatal Stevens-Johnson syndrome in an AIDS patient treated with sulfadiazine. Ann Pharmacother. 1999 Mar;33(3):379-80. No abstract available.PMID: 10200866; UI: 99216873. [See Related Articles] Arola O, et al. Arthritis, uveitis, and Stevens-Johnson syndrome induced by trimethoprim. Lancet. 1998 Apr 11;351(9109):1102. No abstract available.PMID: 9660586; UI: 98322023. [See Related Articles] Cotter JB. Methazolamide-induced Stevens-Johnson syndrome: a warning! Arch Ophthalmol. 1998 Jan;116(1):117. No abstract available.PMID: 9445224; UI: 98106002.

79. Lawsuit Alleges Children's Motrin Causes Stevens-Johnson Syndrome Lawsuit Alleges Children s Motrin Causes stevensjohnson syndrome. Source BusinessWire Published December 29, 2004. A lawsuit filed Tuesday against http://www.legalnewswatch.com/news_505.html

News Lawyer Directory News Web Welcome Legal News Watch is an online news service, updated weekdays, since 2002. Services Lawyer Directory About About Us Contact Us Advertise With Us RSS / XML published by Related Sites Asbestos Today Blawg Republic Pill Blog Friday September 09, 2005 Lawsuit Alleges Children's Motrin Causes Stevens-Johnson Syndrome Source: Business Wire Published: December 29, 2004 "This lawsuit is the only warning label that the public is going to get until Johnson & Johnson re-labels Children's Motrin, so that it carries a warning about the dangers of Stevens-Johnson Syndrome," Plaintiff's attorney Browne Greene said. The complaint charges the defendants with negligence, breach of express and implied warranties, and deceit by concealment. "Johnson & Johnson and the other Defendants' failure to warn the public about the possible risk of Stevens-Johnson Syndrome, or any other serious skin reactions associated with using Children's Motrin makes it an unsafe product and dangerous to sell to consumers," the Plaintiff contends. The Plaintiff contends that the Defendants knew about the connection between Children's Motrin and these severe, potentially fatal reactions since the late 1980s.

80. Bextra & Stevens Johnson Syndrome - Skinassn.org Stevens Johnson syndrome Your Legal Rights Contact An Attorney SpecializingIn Stevens Johnson syndrome Copyright © 2005 Skinassn.org. http://www.skinassn.org/bextra-stevens-johnson-syndrome.html

Stevens Johnson Syndrome What is Stevens Johnson Syndrome? Causes Of Stevens Johnson Syndrome Toxic Epidermal Necrolysis ... Contact An Attorney Specializing In Stevens Johnson Syndrome Bextra, a drug manufactured by pharmaceutical giant Pfizer, was approved in America by the Food and Drugs Administration in November 2001. This drug was put into the same group as some other drugs, which were collectively known as cox-2 inhibitors. Bextra, along with other Cox-2s, were prescribed for osteoarthritis, menstrual cramps, and adult pain management. All cox-2 inhibitors, including Bextra, received a very enthusiastic welcome from both medical professionals and patients. This was because the non-steroid anti-inflammatory drugs traditionally prescribed for these problems affected both the cox-1 enzyme and the cox-2 enzyme produced by the body. Because the cox-1 enzyme is responsible for protecting the lining of the stomach, many patients suffered chronic gastric problems. However, cox-2 inhibitors like Bextra were able to isolate and inhibit just the cox-2 enzyme, thus reducing the risk of gastric problems dramatically. However, this benefit was to come at a high price, and it was not long before the potentially deadly side effects of Bextra became known. In fact, it is alleged that the FDA and Pfizer officials knew about these links even before drug was approved, and yet is was still approved and widely prescribed. The side effect was known as Stevens-Johnson Syndrome, also known as SJS. Along with another variation of the disease, Toxic Epidermal Necrolysis, this was a deadly side effect that could result from long term use of Bextra.

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