81. Neurological Disorders | Spinal Muscular Atrophy spinal muscular atrophy (SMA) is a group of genetic diseases that affects the part of the nervous system that controls voluntary muscle movements, http://www.ucsfhealth.org/childrens/medical_services/neuro/atrophy/

University of California, San Francisco About UCSF Search Welcome Hospitals and Clinics Appointments Billing ... Other Resources Spinal Muscular Atrophy Print Format Spinal muscular atrophy (SMA) is a group of genetic diseases that affects the part of the nervous system that controls voluntary muscle movements, such as crawling, walking, head and neck control and swallowing. The disease causes weakness and wasting of the voluntary muscles. Most nerve cells that control muscles, called motor neurons, are located in the spinal cord. Motor neurons send electrical and chemical messages to the muscles. In SMA, the motor neurons don't send enough signals to the muscle cells, the muscles don't function properly and the muscles deteriorate. SMA affects infants, children and adults. It's estimated that the condition occurs at a rate of 1 in every 6,000 births. Childhood SMA is an autosomal recessive disease, meaning it runs in families. Children inherit a gene from both their mother and father, although parents may not have symptoms. An estimated 1 in 40 "normal" people are carriers of the SMA gene. If both a man and woman carry the gene, their child has a 25 percent chance of developing the condition. For more information or to make an appointment, please contact:

82. Spinal Muscular Atrophy - Columbia Researchers Receive $3 Million To Combat Gene spinal muscular atrophy Foundation provides funding to support the discovery and advancement of novel products to treat SMA Researchers at Columbia http://www.medicalnewstoday.com/medicalnews.php?newsid=20793

83. Map & Graph: Countries By Mortality: Spinal Muscular Atrophy And Related Syndrom spinal muscular atrophy and related syndromes; Infantile spinal muscular atrophy, type I WerdnigHoffman; Other inherited spinal muscular atrophy; Motor http://www.nationmaster.com/graph-T/mor_spi_mus_atr_and_rel_syn

Supporter Benefits Signup Login Sources ... Pies Factoid #33 Aussies picked up the most medals each at the Sydney Olympics , which brings them into the all time top 11 Interesting Facts Make your own graph: Hold down Control and click on several. Compare All Top 5 Top 10 Top 20 Top 50 Top 100 Bottom 100 Bottom 20 Bottom 10 Bottom 5 All (desc) in category: Select Category Agriculture Crime Currency Democracy Disasters Economy Education Energy Environment Food Geography Government Health Identification Immigration Industry Internet Labor Language Lifestyle Media Military Mortality People Religion Sports Taxation Transportation with statistic: view: Correlations Printable graph / table Pie chart Scatterplot with ... * Asterisk means graphable. What's new? Our next offering Latest newsletter Student area Lesson plans Top Countries The most requested countries (descending order): United States Canada India China ... Mortality : Spinal muscular atrophy and related syndromes View this stat: Per capita Show map full screen Country Description Definition: Total for all ages and sexes. Database compiled January 2004. Total of figures for: Spinal muscular atrophy and related syndromes Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]

84. Map & Graph: Countries By Mortality: Spinal Muscular Atrophy And Related Syndrom spinal muscular atrophy and related syndromes; Infantile spinal muscular atrophy, type I WerdnigHoffman; Other inherited spinal muscular atrophy http://www.nationmaster.com/graph-T/mor_spi_mus_atr_and_rel_syn_cap

Supporter Benefits Signup Login Sources ... Pies Factoid #135 Australians lead the world in hours worked and membership in many voluntary organizations . How do they find the energy? Interesting Facts Make your own graph: Hold down Control and click on several. Compare All Top 5 Top 10 Top 20 Top 50 Top 100 Bottom 100 Bottom 20 Bottom 10 Bottom 5 All (desc) in category: Select Category Agriculture Crime Currency Democracy Disasters Economy Education Energy Environment Food Geography Government Health Identification Immigration Industry Internet Labor Language Lifestyle Media Military Mortality People Religion Sports Taxation Transportation with statistic: view: Correlations Printable graph / table Pie chart Scatterplot with ... * Asterisk means graphable. What's new? Our next offering Latest newsletter Student area Lesson plans Top Countries The most requested countries (descending order): United States Canada India China ... Mortality : Spinal muscular atrophy and related syndromes (per capita) View this stat: Totals Show map full screen Country Description Definition: Total for all ages and sexes. Database compiled January 2004. Total of figures for: Spinal muscular atrophy and related syndromes Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]

85. The Vest™ Airway Clearance System - Spinal Muscular Atrophy Case Study spinal muscular atrophy and Atelectasis Pulmonary function in spinal muscular atrophy. J Child Neurol 1994; 9(3) 326329. http://www.thevest.com/conditions/sma/default.asp?gs=patients

86. ► Spinal Muscular Atrophy A medical encycopedia article on the topic spinal muscular atrophy. http://www.umm.edu/ency/article/000996.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Z Maryland Medical Center Programs UM Spine Center Home Medical Reference Encyclopedia (English) Toggle English Spanish Spinal muscular atrophy Overview Symptoms Treatment Prevention Definition: A group of inherited diseases that cause progressive muscle degeneration and weakness , eventually leading to death. Alternative Names: Werdnig-Hoffmann disease Causes, incidence, and risk factors: Spinal muscular atrophy (SMA) is the second leading cause of neuromuscular disease. It is inherited as an autosomal recessive trait (a person needs to get the defective gene from both parents to be affected) and has an incidence of approximately 4 per 100,000 people. In its most severe form (SMA I), infants are born floppy with weak, thin muscles and feeding and breathing problems . Their lifespan seldom exceeds 2 to 3 years. Infants with SMA II have less severe symptoms during early infancy, but they become progressively weaker with time. Survival time with type II is longer, but the disease kills most of those affected while they are still children. SMA III is the least severe form of the disease, and symptoms may not appear until the second year of life. Often

87. Neurological Disorders - Spinal Muscular Atrophy spinal muscular atrophy is a rare degenerative problem that affects the There are four types of spinal muscular atrophy based on symptoms and age of http://www.chkd.org/neurology/sma.asp

More Health Information Adolescent Medicine Allergy/Immunology Anesthesiology Arthritis Burns Cardiology Craniofacial Dental Medicine Dermatology Developmental Peds Diabetes Digestive Ear, Nose, Throat Genetics Gastroenterology Growth Hematology High Risk Newborn High Risk Pregnancy Infectious Disease Mental Health Neonatology Nephrology Neurology Normal Newborn Normal Pregnancy Oncology Ophthalmology Orthopedics Otolaryngology Pediatric Intensive Care Pediatric Surgery Pediatrics Physical Medicine Plastic Surgery Respiratory/Pulmonology Rheumatology Safety Surgery Terminal Transplant Urology Site Search For a doctor who specializes in this topic, click here. Spinal Muscular Atrophy What is spinal muscular atrophy (SMA)? Spinal muscular atrophy is a rare degenerative problem that affects the spinal cord and nerves, resulting in muscle wasting and weakness. What causes spinal muscular atrophy? SMA is an autosomal recessive disease. This means that both males and females are equally affected, and that two copies of the gene, one inherited from each parent, are necessary to have the condition.A gene called survival motor neuron (or SMN) is found to have an abnormal area (called a deletion) in over 95 percent of cases of SMA. Symptomatic individuals of all ages can be tested through DNA studies typically done from a blood sample. When both parents are carriers, there is a one in four, or 25 percent, chance, with each pregnancy, to have a child with SMA. Carrier testing for the general population is technically difficult and usually available only if a previously affected child in the family has been studied.

88. BioMed Central | Full Text | SMN1dosage Analysis In Spinal Muscular Atrophy From SMN1 dosage analysis in spinal muscular atrophy from India spinal muscular atrophy (SMA) represents the second most common fatal autosomal recessive http://www.biomedcentral.com/1471-2350/6/22

home journals A-Z subject areas advanced search ... Volume 6 Viewing options Abstract Full text PDF Associated material: Pre-publication history PubMed record Related literature: Articles citing this article on Google Scholar Other articles by authors Kesari A ... Similar articles (PubMed) Tools: E-mail to a friend Download references Post a comment Key E-mail Corresponding author Research article dosage analysis in spinal muscular atrophy from India Akanchha Kesari Hanna Rennert Debra GB Leonard and Balraj Mittal Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-14, U.P, India Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia USA Current Address- Center for Genetic Medicine, Children's National Medical Center Washington- DC. USA Department of Pathology and Laboratory Medicine, Newyork Presbyterian Hospital, Cornell Campus, Newyork USA BMC Medical Genetics The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2350/6/22 Received Accepted Published This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0

89. BrainTalk Communities - Spinal Muscular Atrophy Online patient support groups for healthcare and neurology. http://brain.hastypastry.net/forums/archive/index.php/f-238.html

BrainTalk Communities Specific Neurological Conditions (M - Z) PDA View Full Version : Spinal Muscular Atrophy Useful Websites New research om SMA New Member w/Q ... hello i'm new in the net

90. BrainTalk Communities - Spinal Muscular Atrophy Reload this Page spinal muscular atrophy Threads in Forum spinal muscular atrophy, Forum Tools, Search this Forum http://brain.hastypastry.net/forums/forumdisplay.php?f=238

91. Core Curriculum - POSNA Discuss the prognosis for the differing types of spinal muscular atrophy Although the orthopaedist will see patients with spinal muscular atrophy from http://www.posna.org/index?service=page/coreCurriculum&article=spinalMuscularAtr

92. Special Child: Disorder Zone Archives - Spinal Muscular Atrophy spinal muscular atrophy (SMA) is a hereditary disease characterized by He was diagnosed with WerdnigHoffman (AKA spinal muscular atrophy Type I) http://www.specialchild.com/archives/dz-023.html

Disorder Zone Archives Spinal Muscular Atrophy Madison Reed Devon Stants Introduction Spinal Muscular Atrophy (SMA) is a hereditary disease characterized by wasting of the skeletal muscles caused by progressive degeneration of the anterior horn cells found in the spinal cord. It is the second most common childhood neuromuscular disorder and is caused by a deletion or mutation on chromosome 5q. Muscle atrophy and weakness occur in the voluntary muscles that are used for walking, crawling, head and neck control, and swallowing. SMA is an autosomal recessive disorder, which means that both parents must be carriers of the defective gene and both parents much each pass the SMA gene to the child (receiving one defective gene will not cause SMA). The likelihood of parents passing the gene on to their offspring and having an affected child is 25%, or a 1 in 4 chance. One in 40 people are carriers of SMA and the occurrence rate is estimated to be 1 in every 6,000 to 10,000 live births (with some forms more common than others). The first substantive descriptions of SMA occurred at the end of the 19 th century when Drs. Werdnig and Hoffman characterized the features of autosomal recessive SMA. Later, in 1950, Dr. Brandt reported 112 cases of progressive SMA and noted that an EMG and a muscle biopsy were useful in establishing a diagnosis. Then, in 1965, Drs. Kugelberg and Welander reported several patients with a later onset of SMA and a more prolonged course. Finally, in 1973, Dr. Pearn published a series of papers that were considered the most important documentation of the clinical, epidemiologic, and genetic

93. Disease - Spinal Muscular Atrophy Type III (SMA-3) Clinical Findings, spinal muscular atrophy (SMA) is characterized by progressive degeneration and loss of the anterior horn cells (ie, lower motor neurons) http://disability.ucdavis.edu/resources/diseases/list/disease.asp?id=10

94. Disease - Spinal Muscular Atrophy Type I (SMA-1) Also known as Infantile spinal muscular atrophy (SMA) Type I, the disorder is characterized by degeneration of groups of nerve cells (motor nuclei) within http://disability.ucdavis.edu/resources/diseases/list/disease.asp?id=11

95. Spinal Muscular Atrophy Genes and disease provides short descriptions of inherited disorders. It is hosted by the National Center for Biotechnology Information (NCBI), http://www.ncbi.nlm.nih.gov/disease/SMA.html

This Genes and Disease page has been moved to: Please update your bookmarks. If you are not automatically transported to the new page after 15 seconds, click on this link Genome View on chromosome 5 Databases PubMed the literature LocusLink collection of gene-related information OMIM catalog of human genes and disorders Information Families of Spinal Muscular Atrophy a nonprofit organization that raises funds for SMA research and supports families affected by SMA DEATH OF SPINAL MOTOR NEURONS and subsequent muscle paralysis characterize Spinal Muscular Atrophy (SMA), a hereditary neuromuscular disorder that is the most common genetic cause of childhood fatality. The age of onset and severity of SMA varies from an infantile onset form (type I) which causes early death from respiratory failure, to milder juvenile onset forms in which affected individuals show reduced life expectancy (type II), and are unable to walk (types II and III). The function of SMN1 is currently being investigated by studies in rats and transgenic mice. It is hoped that the characterization of this protein and its function will eventually lead to a therapy that may be used in conjunction with genetic testing already in place to help control the incidence and/or severity of SMA.

96. Spinal Muscular Atrophy spinal muscular atrophy Death of spinal motor neurons and subsequent muscle paralysis characterize spinal muscular atrophy (SMA), a hereditary neuromuscular http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.sect

97. Spinal Muscular Atrophy spinal muscular atrophy resources and links. Rate It 0.00 / 0 Votes . Refine. Show them all, USA, Alabama, Alaska, Arizona, Arkansas, California http://www.disabilityonline.com/categories/disorders_and_diseases/spinal_muscula

Match Any Match All the whole Directory This Category Only Within your results Home Disorders and Diseases Spinal Muscular Atrophy .:General Listings 1 - 3 of 3 Living SMArt Living SMAart, a newsletter written by and for adults with Spinal Muscular Atrophy. Rate It [ 0.00 / Votes ] Melissa's Page My site is about my personal experiences growing up with Spinal Muscular Atrophy. Also includes links to many disability related sites. Rate It [ 0.00 / Votes ] Spinal Muscular Atrophy Spinal Muscular Atrophy resources and links. Rate It [ 0.00 / Votes ] Refine: Show them all USA Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Puerto Rico Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming CANADA Alberta British Columbia Manitoba New Brunswick Newfoundland Northwest Territories Nova Scotia Nunavut Ontario Prince Edward Island Quebec Saskatchewan Yukon Territory INTERNATIONAL Afghanistan Albania Algeria American Samoa Andorra Angola Anguilla Antarctica Antigua Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia Bosnia and Herzegovina Botswana Brazil British Virgin Islands Brunei Bulgaria Burkina Faso Burma Burundi Cambodia

98. THE MERCK MANUAL--SECOND HOME EDITION, Spinal Muscular Atrophies In Ch. 95, Peri There are three main types of spinal muscular atrophy. In children with intermediate (type II) spinal muscular atrophy, weakness develops by age 6 http://www.merck.com/mmhe/sec06/ch095/ch095j.html

var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Brain, Spinal Cord, and Nerve Disorders Chapter Peripheral Nerve Disorders Topics Introduction Hereditary Neuropathies Mononeuritis Multiplex Mononeuropathy ... Polyneuropathy Spinal Muscular Atrophies Thoracic Outlet Syndromes Spinal Muscular Atrophies Buy The Book Print This Topic Email This Topic Pronunciations amniocentesis atrophy electromyography mononeuropathy ... thoracic Spinal muscular atrophies are hereditary disorders in which nerve cells in the spinal cord and brain stem degenerate, causing progressive muscle weakness and wasting. The disorders are usually inherited as a recessive autosomal (not sex-linked) trait: two genes are required, one from each parent (see

99. Spinal Muscular Atrophy International. 22 chapters. Founded 1984. (Multilingual) Funding of research, support and networking http://webcenter.health.webmd.netscape.com/hw/brain_nervous_system/shc29sma.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... Families of S.M.A. (Spinal Muscular Atrophy) Spinal Muscular Atrophy Families of S.M.A. (Spinal Muscular Atrophy) International. 22 chapters. Founded 1984. (Multilingual) Funding of research, support and networking for families affected by spinal muscular atrophy types I, II, III, adult onset and Kennedy's. Educational resources, group development guidelines, quarterly newsletter, pen pals, phone support and videotapes. Online message boards and kids corner support. WRITE: Families of S.M.A. P.O. Box 196 Libertyville, IL 60048-0196 CALL: 1-800-886-1762 FAX: 847-367-7623 E-MAIL: sma@fsma.org WEBSITE: http://www.fsma.org http://www.curesma.com VERIFIED: 5/17/2004 The above information was "verified" as correct on the date at the end of each entry. Since American Self-Help Group Clearinghouse's database is extensive but staffing is limited and information for these organizations can change, it is not possible to keep every entry in American Self-Help Group Clearinghouse database completely current and accurate. Please check with the organizations listed for the most current information. For additional information on self-help groups, please visit the American Self-Help Group Clearinghouse web site at http://www.mentalhelp.net/selfhelp

100. Spinal Muscular Atrophy - HUM-MOLGEN I have recently seen a 6 years old boy whith spinal muscular atrophy confirmed by biosy. The familiy is interested in molecular studies. http://hum-molgen.org/bb/Forum2/HTML/000107.html

home genetic news bioinformatics biotechnology ... DIAGnostics - Clinical Research (professional requests) Spinal Muscular Atrophy profile register preferences faq ... next oldest topic Author Topic: Spinal Muscular Atrophy marivicervera Member posted 08-13-2002 06:48 PM I have recently seen a 6 years old boy whith spinal muscular atrophy confirmed by biosy. The familiy is interested in molecular studies. I would like to know if anyone is working on this studies. Thank you. Marivi Cervera M.D. IP: 152.163.201.187 All times are ET (US) next newest topic next oldest topic Administrative Options: Close Topic Archive/Move Delete Topic Hop to: Select a Forum or Archive List of Forums: Biotechnical requests and sources DIAGnostics - Clinical Research (professional requests) Ethical, legal and social implications Open Topic Forum List of Archives: Genetic News DIAGnostics - Clinical Research Contact Us HUM-MOLGEN HUM-MOLGEN Powered by: Ultimate Bulletin Board, Version 5.44a By posting requests at HUM-MOLGEN you reach more than 9.500 mailing list subscribers and a 6 digit number of www users. Therefore post high quality messages only, including full name and institutional address.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 5     81-100 of 120    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20