61. Coed Compression spinal cord compression. This is a major medical oncology emergency that can happen in any patient who has advanced cancer. Delay in appropriate treatment http://www.tirgan.com/cordcom.htm

Home l Services l Support Search ... E-Mail Spinal Cord Compression This is a major medical oncology emergency that can happen in any patient who has advanced cancer. Delay in appropriate treatment of this condition can result in permanent paralysis, loss of bladder and bowel function. This condition is due to the spread of cancer to the spine and tissues around the spinal cord that may result in compression of the cord. Signs and Symptoms: Pain in the back or radiating from the back. Pain can be exacerbated by coughing or movement. Loss of sensation in lower part of the body Retention of urine Bowel and bladder dysfunction, incontinence Diagnosis This is achieved by CT Scan or MRI of the Spine. Treatment: Treatment of this condition should be started promptly by one or several of the following methods: Radiation therapy Steroids Chemotherapy Surgery If cancer patients have any signs or symptoms of cord compression, they should contact their medical oncologist or their primary medical doctor so that treatment may begin immediately. The success of treatment depends on how early the intervention begins. Sometimes a tissue diagnosis is required. A neurosurgeon or another specialist will take a

62. ABCP - Cord Compression A spinal cord compression is most commonly caused by the metastases of tumors such as prostate, lung, and breast. Most of these lesions occur in the http://www.albertabreast.com/patientinfo/cordcomp.php

Patient Info Bone Imaging Breast Cancer Staging Breast Cancer Treatment Overview Clinical Trials ... Patient Guide To Radiation Therapy Link to Dictionary of Cancer Terms (CancerNet) CCI Patient Info FDG PET Imaging Site is HONcode compliant Cord Compression Etiology/physiology A spinal cord compression is most commonly caused by the metastases of tumors such as prostate, lung, and breast. Most of these lesions occur in the thoracic spine, but the lumbosacral and cervical regions may also be affected. A cord compression may occur at any time during the disease course, from presentation and initial diagnosis to advanced, terminal disease. Assessment/diagnosis Pain evaluation - Back pain is the most common presenting symptom, occurring in approximately 95% of patients. Pain is gradual at onset becoming progressively more severe. This pain may be experienced as The development of a spinal cord compression is considered a medical emergency , for without prompt treatment, permanent paralysis may result If you suspect you may have cord compression

63. WSAVA 2001 - Basic Principles Of Spinal Cord Compression In IVDD, there is spinal cord compression without instability. With chronic (over 10 days) spinal cord compression, 50% of the spinal cord diameter is http://www.vin.com/VINDBPub/SearchPB/Proceedings/PR05000/PR00213.htm

Basic Principles of Spinal Cord Compression Joane Parent Canada Spinal cord diseases are frequent in the dog. To review the basic principles of lesion localization as it relates to the spinal cord, intervertebral disc disease has been used as model. In IVDD, there is spinal cord compression without instability. The spinal cord is composed of an outer layer of white matter and a core of gray matter. The white matter is made of axons while the gray matter is composed of cell bodies. Clinically, lesions that are limited to the gray matter behave similarly to lesions of the peripheral nervous system. It is the involvement of the white matter that leads to clinical signs of spinal cord disease. Anatomical considerations (spinal cord white matter) Ascending sensory fibers: Proprioceptive fibers A.   Reflex proprioceptive pathways:                 Hind limbs: Dorsal and ventral spinocerebellar                Fore limbs: Rostral spinocerebellar B.   Conscious proprioceptive pathways:                Hind limbs: Fasciculus gracilis                Fore limbs: Fasciculus cuneatus                Nociception (pain perception) fibers Descending motor fibers (Upper Motor Neurons):                               Reticulo-spinal tracts                               Vestibulo-spinal tracts                               Rubro-spinal tracts                               Cortico-spinal tracts Clinical signs associated with involvement of the spinal cord ascending sensory pathways: a. Proprioceptive ataxia

64. Log In Problems The nurse can favorably affect a patient´s quality of life through timely recognition of early signs and symptoms of SCC. http://www.medscape.com/viewarticle/442735

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65. Log In Problems The nurse can favorably affect a patient´s quality of life through timely recognition of early signs and symptoms of SCC. http://www.medscape.com/viewarticle/442735_6

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66. Malignant Epidural Spinal Cord Compression Malignant epidural spinal cord compression of the paper looks at the best treatment options for the different stages of spinal destruction/compression. http://www.lrf.org.uk/en/1/infnurjounurmal.html

Nursing Leukaemia Journal reviews Nursing practice Breaking bad news... ... Environment for dying... Spinal neurological function... SHOT... The transfusion practitioner... Haematological cancers (NICE) Infusion therapy (RCN) ... Send to friend Journal Review Malignant epidural spinal cord compression Author(s) Shaw P and Marks A Publication European Journal of Palliative Care Reference Vol. 19 (5) page 142-143 Publication Date October 2003 Relevant to nurses in haematology as the paper discusses the symptoms, diagnosis and treatment options. Although the paper is not specifically focused on haematology patients the issues remain the same, as haematology nurses we are all familiar with the problems of mobility, pain control and continence. Within the paper the challenge of treatment options is discussed although no clear guidance is given the authors discuss the three main options - steroids, radiotherapy, surgery and on occasions chemotherapy. Recognition and early treatment remain the best options for preserving neurological function and controlling pain. A section of the paper looks at the best treatment options for the different stages of spinal destruction/compression.

67. Myelopathies - spinal cord compression by degenerative spine disease is one of the more common The symptomatology (symptoms and signs) of spinal cord compression http://www.neuroanatomy.wisc.edu/SClinic/Myelo/Myelopathy.htm

Spinal cord Weakness Radiculopathy Compression myelopathy ... Anatomy Compression Myelopathies Spinal cord compression by degenerative spine disease is one of the more common causes of myelopathy, however tumors or other masses can also cause myleopathies. Intraspinal tumors may originate in the substance of the spinal cord (intramedullary tumors) or compress it from the outside (extramedullary tumors). Extramedullary tumors may be inside the dura mater (intradural) or outside the dura mater (extradural). Some tumors are dumbbell shaped, with intra and extra spinal components. Although the case history may provide clues to the pathologic nature of the tumor, compression from a mass results in the clinical syndrome of myelopathy. Compression may often involve a radicular component (radiculomyelopathy). The symptomatology (symptoms and signs) of spinal cord compression consists of sensory (pain, numbness and paresthesia), motor and autonomic disturbances, the nature and extend of which is related to: * the level that is compressed - high or low cervical, high and low thoracic, lumbosacral

68. DrDillin.com: Cervical Spinal Stenosis spinal cord compression External objects can compress the spinal cord changing the shape and This compression effects the function of the spinal cord. http://www.drdillin.com/education/basics_css_compression.htm

Spine Basics: Cervical Spinal Stenosis Spinal Cord Compression External objects can compress the spinal cord changing the shape and interrupting the spinal cord's normal function. External pressure from anatomic structures can narrow the spinal canal to the point where spinal cord compression occurs. The spinal cord exists in the space bounded by the ring. Narrowing leads to spinal cord pressure and change in spinal cord shape. This compression effects the function of the spinal cord. Side View Top View Clinical Evaluation Stenosis Ring Concept Connected Ring Concept Spinal Cord Compression Spinal Cord Organization Spinal Cord Syndromes Definition of Stenosis Practice Information Menu About Dr. Dillin Contact Us Make An Appointment Office Maps and Directions Consultations Treated Spine Conditions Spine Operations Philosophical Heritage Download Patient Forms Practice Home Page Spine Education Menu Spine Animations Spine Basics Spine Definitions Spine Conditions Spine Procedures Spine Editorials Spine References Surgeon's Lounge Spine Links Site Design by Swarm Orthopedic

69. DrDillin.com: Cervical Spinal Stenosis Different degrees of spinal cord compression, and how fast it develops The critical issue in cervical spinal stenosis with cord compression is the http://www.drdillin.com/education/basics_css.htm

Spine Basics: Cervical Spinal Stenosis History of Neck Spinal Stenosis Cervical (neck) spinal stenosis produces symptoms due to spinal cord compression. If the spinal canal in the neck is narrow enough, then the natural motion of the neck may compress the spinal cord. In flexion (bending the neck forward), the spinal cord may be compressed against structures on the floor of the canal (bone spur, disc). In extension, the spinal canal becomes narrower and the spinal cord can be compressed by both the roof structures indenting the spinal cord from behind and driving the cord against the front structures on the floor. Compression in the neck effects the spinal cord and potentially produces symptoms in the arms, legs and occasionally the bowel and bladder. Compressing the spinal cord is frequently painless. Patients with cord compression that develops slowly may experience numbness in the hands, clumsiness in the hands, shooting numbness down the trunk, arms or legs with neck motion, balance difficulties when walking, an unsteady gait and occasionally disturbance in bowel and bladder function. Physical Exam of Spinal Stenosis The physical exam is performed by the doctor to determine the effects of stenosis. An examination of the function of the nerves in the arms and legs may reveal weakness, numbness or reflex change. Abnormal reflex patterns may appear with long standing spinal cord compression.

70. BioMed Central | Full Text | Epidural Spinal Cord Compression To obtain access to Current Treatment Options in Neurology through your institution use the options below. If you would like information about a personal http://www.biomedcentral.com/1092-8480/6/285

home journals A-Z subject areas advanced search ... my BioMed Central To obtain access to Current Treatment Options in Neurology through your institution use the options below. If you would like information about a personal subscription, please contact subs@phl.cursci.com Click here to view an abstract of this article Click here to login if you are already a subscriber to Current Treatment Options in Neurology Subscribe to Current Treatment Options in Neurology Register for a free online trial Ask your librarian to investigate institutional access Athens users please click here to gain access If you believe you are seeing this page in error, or cannot activate your subscription, e-mail us info@biomedcentral.com Terms and Conditions Privacy statement Information for advertisers ... Contact us

71. BioMed Central | Abstract | Epidural Spinal Cord Compression Epidural spinal cord compression Robert Cavaliere MD and David Schiff MD Epidural spinal cord compression is a neurologic emergency requiring immediate http://www.biomedcentral.com/1092-8480/6/285/abstract

home journals A-Z subject areas advanced search ... Issue 4 Viewing options Abstract Full text PDF Associated material: PubMed record Related literature: Articles citing this article on Google Scholar Other articles by authors Cavaliere R ... Similar articles (PubMed) Tools: E-mail to a friend Download references Opinion Epidural Spinal Cord Compression Robert Cavaliere MD and David Schiff MD Division of Neuro-oncology Department of Neurology, Box 800432, University of Virginia, Charlottesville, VA, 22908, USA Current Treatment Options in Neurology Published Abstract Terms and Conditions Privacy statement Information for advertisers Contact us

72. Sao Paulo Medical Journal - spinal cord compression in bthalassemia follow-up after radiotherapy. ABSTRACT. CONTEXT spinal cord compression due to extramedullary hematopoiesis is a http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000600009

73. Fluoride & Spinal Stenosis spinal cord compression in bone fluorosis. Apropos of 4 cases Article in A case of skeletal fluorosis with spinal cord compression from Kekirawa http://www.fluoridealert.org/health/bone/fluorosis/stenosis.html

HEALTH EFFECTS HOMEPAGE Accidents ... Useful Links HEALTH EFFECTS: DIRECTORY: FAN Health Bone Fluorosis Key Findings 1) Excessive exposure to fluoride causes a bone disease called skeletal fluorosis 2) In the advanced stages of skeletal fluorosis , the spine may develop extensive ligament calcifications and bone spurs (osteophytes), which in turn can produce a narrowing of the spinal canal and damage to the spinal cord (aka spinal stenosis). 3) The cervical region of the spine is the most common site for fluoride-induced stenosis General Info Spinal Stenosis: "Spinal stenosis is a narrowing of spaces in the spine (backbone) that results in pressure on the spinal cord and/or nerve roots ... Spinal stenosis most often results from a gradual, degenerative aging process ... As people age, the ligaments of the spine may thicken and calcify (harden from deposits of calcium salts). Bones and joints may also enlarge, and

74. Spinal Granulocytic Sarcoma (chloroma) Presenting As Acute Cord Compression In A Granulocytic sarcoma (chloroma) causing spinal cord compression. Neuroradiology 1993;35750911. Back to cited text no. 9. 10. Kook H, Hwang TJ, Choe K, http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2005;volume=53;iss

75. ASB: MECHANISMS IN SPINAL CORD INJURY Figure 1 Effect of Cord Compression on Motor Responses. Figure 2 65% spinal cord compression (Typical). REFERENCES. McNeice GM et al. http://asb-biomech.org/onlineabs/abstracts96/mcneice.html

AMERICAN SOCIETY OF BIOMECHANICS Presented at the 20th Annual Meeting of the American Society of Biomechanics Atlanta, Georgia. October 17-19, 1996 COMPONENT MECHANISMS IN SPINAL CORD INJURY - AN ANIMAL MODEL FOR DRUG TREATMENT PROTOCOLS - G.M. McNeice (1), W.A. Lee (1), K.C. Lennon (1), C.D. Riddle (1), R.L. Ferguson (1), M. LaBerge (2) (2) GHS/Clemson University Biomedical Cooperative, Greenville, S.C. 29605, USA INTRODUCTION Spinal cord injury models continue to be used to study the pathophysiology of injury and the potential of various therapeutic treatments. Recent NIH (Young et. al., 1995) supported studies have aimed at standardizing the impact trauma to the cord in the rat model. The present authors have discussed some potential errors inherent in the NYU proposed model (McNeice et. al., 1994, 1995) and introduced a refined rat model using a miniature accelerometer that allows the biomechanics of the impact to be established. The NYU model excludes the effect of cord compression on the neurologic deficit, a factor often seen in human injuries. The present study demonstrates the successful application of this refined model to drug therapy of the impacted cord as well as introduces an extension of the model to include the effects of cord compression. Compression levels of 65% and 85% are demonstrated. REVIEW AND THEORY MODEL AND PROCEDURES In this ongoing study the authors have established an animal model that will address the following component mechanisms of spinal cord injury:

76. ACR - ANA: MRI Tops CT At Predicting Spinal Cord Injury Outcome The extent of spinal cord compression as measured by MRI correlated with the initial amount of clinical neurological impairment, they found in a study http://www.acr.org/s_acr/sec_healthnews.asp?CID=3155&DID=19093

77. Management Of Pain And Spinal Cord..., Annals 6 Jul 99 Management of Pain and spinal cord compression in Patients with Advanced Data on assessment and treatment of spinal cord compression are reviewed. http://www.acponline.org/ethics/abrahm.htm

Home Search Site directory About the Center ... Annual Session Ethics Program End-of-Life Care About the Panel Physician Education Patient Education Upcoming Conferences ... Resources Managed Care Ethics About the Work Group Statement of Principles Annotated Bibliography Resources Internal Policy Additional Bioethics Resources Volunteering as a Physician Books ... Contact Us Management of Pain and Spinal Cord Compression in Patients with Advanced Cancer Janet L. Abrahm, MD, for the ACP-ASIM End-of-Life Care Consensus Panel Ann Intern Med 1999;131:37-46. Annals of Internal Medicine This paper was written by Janet Abrahm, MD, and was developed for the American College of Physicians-American Society of Internal Medicine (ACP-ASIM) End-of-Life Care Consensus Panel. Members of the ACP-ASIM End-of-Life Care Consensus Panel were Bernard Lo, MD ( Chair ); Janet Abrahm, MD; Susan Block, MD; William Breitbart, MD; Ira R. Byock, MD; Kathy Faber-Langendoen, MD; Lloyd W. Kitchens Jr., MD; Paul Lanken, MD; Joanne Lynn, MD; Diane Meier, MD; Timothy E. Quill, MD; George Thibault, MD; and James Tulsky, MD. Primary staff to the Panel were Lois Snyder, JD ( Project Director ); Jason Karlawish, MD; and Karine Morin, LLM. This paper was reviewed and approved by the Ethics and Human Rights Committee and the Education Committee, although it does not represent official ACP-ASIM policy. Members of the Ethics and Human Rights Committee were Risa Lavizzo-Mourey, MD (

78. Pathologic Quiz Case: A 37-Year-Old Man With Spinal Cord Compression spinal cord compression caused by metastatic epithelialmyoepithelial Wajed MA, Cardoe N. spinal cord compression due to metastasis from a mixed http://arpa.allenpress.com/arpaonline/?request=get-document&doi=10.1043/1543-216

79. Spinal Cord Trauma spinal cord compression or injury; Compression of spinal cord. Causes. Spinal cord trauma can be caused by any number of injuries to the spine. http://www.ehendrick.org/healthy/001066.htm

Injury Disease Nutrition Poison ... Prevention Spinal cord trauma Definition Spinal cord trauma is damage to the spinal cord that results from direct injury to the cord itself, or from indirect injury from damage to the bones, soft tissues, and blood vessels surrounding the spinal cord. Alternative Names Spinal cord compression or injury; Compression of spinal cord Causes Spinal cord trauma can be caused by any number of injuries to the spine. They can result from motor vehicle accidents, falls, sports injuries (particularly diving into shallow water), industrial accidents, gunshot wounds, assault, and others. A seemingly minor injury can cause spinal cord trauma if the spine is weakened (such as from rheumatoid arthritis or osteoporosis ) or if the spinal canal protecting the spinal cord has become too narrow (spinal stenosis) due to the normal aging process. Direct injury, such as cuts, can occur to the spinal cord, particularly if the bones or the discs have been damaged. Fragments of bone (from fractured vertebrae, for example) or fragments of metal (such as from a traffic accident) can cut or damage the spinal cord. Direct damage can also occur if the spinal cord is pulled, pressed sideways, or compressed. This may occur if the head, neck, or back are twisted abnormally during an accident or injury.

80. Spine And Nerve Center At MGH/Harvard - Links herniated intervertebral discs, and spinal cord compression syndromes. Spine Tumors Back Neck Injury Spinal Cord Injury Spinal AVMs http://neurosurgery.mgh.harvard.edu/Spine/lnkspine.htm

Neurosurgical evaluation of neck and back pain, nerve compression syndromes, herniated intervertebral discs, and spinal cord compression syndromes. Information regarding peripheral nerve (including nerve compression such as carpal tunnel syndrome) and spine surgery and the Neurosurgical Service's Spine Evaluation Unit Spine Referrals Peripheral Nerve Surgeons Spine Surgeons ... Spine Links "Links" are provided only as an informational resource as a "Patient-to-Patient" service. Please note that many of the links provided below are not on one of the MGH Neurosurgical Service servers and are not maintained by us or affiliated with any services provided by us. Spine Tumors Spinal Cord Injury Spinal AVMs Peripheral Nerve ... Ergonomics Links to other information Other information on back and neck pain/injury Spinal cord injury links.

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