41. Smallpox, Cancer, And A Vaccine CNN http://cnn.com/2003/HEALTH/04/01/cancer.vaccines.ap/index.html

42. WHO | Smallpox smallpox is an acute contagious disease caused by Variola virus, a member of the orthopoxvirus smallpox was officially declared eradicated in 1979. http://www.who.int/entity/csr/disease/smallpox/en/

All WHO This site only Home About WHO Countries Health topics ... Diseases covered by CSR Smallpox Preparedness in the event of a smallpox outbreak Programme to facilitate Variola virus research ... Information resources Smallpox is an acute contagious disease caused by Variola virus, a member of the orthopoxvirus family. It was one of the world's most feared diseases until it was eradicated by a collaborative global vaccination programme led by the World Health Organization. The last known natural case was in Somalia in 1977. Since then, the only known cases were caused by a laboratory accident in 1978 in Birmingham, England, which killed one person and caused a limited outbreak. Smallpox was officially declared eradicated in 1979. For more information WHO fact sheet Frequently asked questions and answers on smallpox HIGHLIGHTS Smallpox vaccine stockpiles and research discussed by the World Health Assembly 20 May 2005 Full text Ad Hoc Committee on Orthopoxvirus Infections Report of a meeting, Geneva, 2004 DISEASE OUTBREAKS Poliomyelitis Ethiopia - Update Full text Yellow fever Guinea Full text Cholera West Africa Full text Disease Outbreak News Employment Other UN Sites ... Privacy

43. WHALE  Smallpox By Whale A look at this diseases severity and infectiousness, vaccine damage and failures and links to articles. http://www.whale.to/vaccines/smallpox.html

Smallp ox Hiding smallpox Jenner Vaccine critics Vaccine failure ... Home

44. CNN.com - Rumsfeld Says He'll Take Smallpox Vaccine - Dec. 19, 2002 CNN http://cnn.com/2002/US/12/18/sproject.irq.rumsfeld.lkl/index.html

CNN Europe CNN Asia Languages Spanish Portuguese German Italian Korean Arabic Japanese On CNN TV Transcripts Headline News CNN International ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Rumsfeld says he'll take smallpox vaccine Careful steps would precede Iraq war, he tells Larry King Rumsfeld on Larry King Live Story Tools WASHINGTON (CNN) In an interview Wednesday with CNN's Larry King, Defense Secretary Donald H. Rumsfeld revealed his plans to take the smallpox vaccine, which can carry severe side effects, including death. "I certainly intend to, simply because it's hard to ask people to do something that you're not willing to do yourself," Rumsfeld said, responding to a question posed by King. President Bush has said he, too, will take the vaccine after ordering vaccinations for some military personnel. The vaccine will be administered to about 500,000 troops deployed in high-risk parts of the world under the first phase of the vaccination plan. The inoculations began this month, according to the National Institute of Allergy and Infectious Diseases. The Defense Department said vaccinations will be mandatory except for those who have medical exemptions.

45. The UCLA Louise M. Darling Biomedical Library History And Special Collections Di smallpox vaccination, inoculation, eradication, an online exhibit. http://www.library.ucla.edu/libraries/biomed/smallpox/

46. CNN.com - Soviet-era Test May Have Caused Smallpox Cases - June 15, 2002 CNN http://cnn.com/2002/HEALTH/06/15/smallpox.tests/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US/HELP CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe CNNenEspanol.com CNNArabic.com ... set your edition Languages Spanish Portuguese German Italian Korean Arabic Japanese Time, Inc. Time.com People Fortune EW InStyle Business 2.0 Soviet-era test may have caused smallpox cases The smallpox virus as seen through a microsope. WASHINGTON (CNN) A Soviet biological weapons test in 1971 may have infected 10 people with the smallpox virus and killed three of them, according to a report presented Saturday at the Institute of Medicine where experts are collaborating on whether and when to vaccinate against smallpox. The report, summarized by Dr. Alan Zelicoff of Sandia National Laboratories, said a woman aboard a research ship carrying 11 other people in the Aral Sea in July 1971 apparently was infected by aerosolized smallpox carried by winds from the test site, located on an island miles away from the ship. The official, Soviet-era report said the woman was infected with smallpox when she disembarked at ports of call stopped along the way. But Zelicoff said the woman told him recently that she never left the ship because women were forbidden to do so. If so, Zelicoff said, she must have been infected while aboard the ship. MORE STORIES The history of the smallpox virus EXTRA INFORMATION What is smallpox?

47. JAMA -- Abstract: Smallpox As A Biological Weapon: Medical And Public Health Man Med Decis Making 2004;24192206. ABSTRACT. Is smallpox in again? smallpox and pan-Orthopox Virus Detection by Real-Time 3 -Minor Groove Binder TaqMan http://jama.ama-assn.org/cgi/content/short/281/22/2127

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 281 No. 22, June 9, 1999 Featured Link E-mail Alerts Consensus Statement Article Options Full text PDF Send to a Friend Related articles in this issue ... Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Henderson DA for the Working Group on Civilian Biodefense Articles that cite this article ISI Web of Science (260) ... Contact me when this article is cited Topic Collections Viral Infections Bioterrorism Topic Collection Alerts Smallpox as a Biological Weapon Medical and Public Health Management Donald A. Henderson, MD, MPH Thomas V. Inglesby, MD John G. Bartlett, MD Michael S. Ascher, MD Edward Eitzen, MD, MPH Peter B. Jahrling, PhD Jerome Hauer, MPH Marcelle Layton, MD Joseph McDade, PhD

48. SmallPOX '99 Main Page The Small Press in Ottawa Expo held yearly. Includes general information. http://www.geocities.com/SoHo/4758/SmallPOX99.html

SmallPOX '99 The Small Press in Ottawa eXpo! Catch SmallPOX! Again! SmallPOX'99, the Small Press in Ottawa eXpo slams into the nation's capital for it's second annual creative epidemic of small press and self-published comicbooks, zines, and chapbooks, on Saturday, July 31st, 1999 at the FIRST BAPTIST CHURCH HALL, 140-A Laurier Avenue West at Elgin Street from 2 'til 8PM This awesome eclectic showcase of talent from Ottawa and beyond welcomes back the bulk of enthusiastic exhibitors who made our inaugural event such an eye-popping success! Plus, more mavericks, mavens, and madmen from the cutting edge of the indie publishing world have already snapped up their spot at SmallPOX'99 And, there's still time to book your spot this year. But, hurry. Space is limited again this year! So, avoid disappointment. Reserve your full or half table space now, by completing and submitting our easy to use, online registration form! BOOK NOW! General Info SmallPOX'98 Site Bookmark this site and visit us often! SmallPOX'99 is proudly co-sponsored by Crosstown Traffic Broken Pencil Magazine , and The United Fanzine Organization USA This page was last updated on June 5th, 1999. (c)S.Bourne.

49. JAMA -- Smallpox As A Biological Weapon: Medical And Public Health Management, J smallpox is one of the most serious of these diseases. If used as a biological weapon, smallpox represents a serious threat to civilian populations because http://jama.ama-assn.org/cgi/content/full/281/22/2127

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 281 No. 22, June 9, 1999 Featured Link E-mail Alerts Consensus Statement Article Options Abstract PDF Send to a Friend Related articles in this issue ... Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Henderson DA for the Working Group on Civilian Biodefense Articles that cite this article ISI Web of Science (260) ... Contact me when this article is cited Topic Collections Viral Infections Bioterrorism Topic Collection Alerts Smallpox as a Biological Weapon Medical and Public Health Management Donald A. Henderson, MD, MPH Thomas V. Inglesby, MD John G. Bartlett, MD Michael S. Ascher, MD ... ; for the Working Group on Civilian Biodefense JAMA. ABSTRACT To develop consensus-based recommendations for measures to be taken by medical and public health professionals following the use of smallpox as a biological weapon against a civilian population.

50. Safety And Health Topics: Smallpox smallpox is an acute, contagious, and sometimes fatal disease caused by However, if obtained and deliberately released as a bioweapon, smallpox could http://www.osha.gov/SLTC/smallpox/

U.S. Department of Labor www.osha.gov MyOSHA [skip navigational links] Search Advanced Search A-Z Index Safety and Health Topics Smallpox Smallpox is an acute, contagious, and sometimes fatal disease caused by infection with a virus known as the variola virus. Smallpox outbreaks have occurred from time to time for thousands of years, but in 1980, the disease was declared eradicated following worldwide vaccination programs. Except for stockpiles in high-security laboratories, the virus has been eliminated. However, if obtained and deliberately released as a bioweapon, smallpox could cause a public health catastrophe. The following questions link to safety and health information relevant to smallpox. What OSHA standards apply? What is smallpox? Can smallpox be used as a bioweapon? What controls should be utilized to protect affected workers from exposure to smallpox? ... Where can I find additional information? Related Safety and Health Topics Pages Safety and Health Topics Smallpox OSHA Standards ... Credits Content Reviewed 05/06/2005 Back to Top www.osha.gov

51. Bush Signs Smallpox Vaccine Compensation Law CNN http://cnn.com/2003/HEALTH/05/01/bush.smallpox.ap/index.html

52. CIDRAP >> Smallpox New Item, FDA approves VIG for smallpox shot complications New Item, US pledges smallpox vaccine for world stockpile http://www.cidrap.umn.edu/cidrap/content/bt/smallpox/

Home About Us Center Support Contact Us ... Clinical responses to smallpox vaccine in vaccinia-naive and previously vaccinated populations: undiluted and diluted Lancy-Vaxina vaccine From J Infect Dis , published online Aug 11 Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox From Nat Med , published online Aug 7 Generalized vaccinia, progressive vaccinia, and eczema vaccinatum are rare following smallpox (vaccinia) vaccination: United States surveillance, 2003 From Sep 1 Clin Infect Dis Smallpox vaccination safety summary From DoD, udpated Jul 12 Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases From Jul Nature Med Adventitious agents and smallpox vaccine in strategic national stockpile From Jul Emerg Infect Dis Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: a novel strategy for immune evasion From Jun J Virol Osler and the infected letter Historical review in May Emerg Infect Dis Negative staining electron microscopic protocol for rash illness From CDC, revised Mar 2005

53. CNN.com - Is It Time To Revive Smallpox Vaccinations? - September 4, 2002 CNN http://cnn.com/2002/HEALTH/conditions/09/04/smallpox.decision/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US/HELP CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe CNNenEspanol.com CNNArabic.com ... set your edition Languages Spanish Portuguese German Italian Korean Arabic Japanese Time, Inc. Time.com People Fortune EW InStyle Business 2.0 Is it time to revive smallpox vaccinations? By Christy Feig CNN Medical Unit (CNN) Americans haven't been routinely vaccinated for smallpox since 1972. But the federal government is debating whether a program should be restarted. "The White House is reviewing my recommendations, and hopefully we'll have a decision in the near future," said Health and Human Services Secretary Tommy Thompson. The World Health Organization declared smallpox eradicated worldwide in 1979, but experts said they are concerned the existing virus from labs could fall into the hands of terrorists. "I would say that the risk of a smallpox attack is very real," said U.S. Sen. Bill Frist, R-Tennessee, who is also a physician. "I would say that that risk is increasing compared to say five or 10 years ago, and I would say as a nation that we do remain highly vulnerable if smallpox is used as an instrument of war." Most Americans under 30 haven't been vaccinated, and it's questionable how long the vaccine protects those who have been. For example, one study found that of 621 microbiologists in Maryland who received smallpox revaccination between 1994 and 2001 as a precautionary measure, 6 percent remained immune from their previous vaccinations.

54. CIDRAP >> Smallpox: Current, Comprehensive Information On Pathogenesis, Microbio —Current Status of the US smallpox Vaccination Campaign —Vaccination Schedule —Liability Issues Following smallpox Vaccine Administration http://www.cidrap.umn.edu/cidrap/content/bt/smallpox/biofacts/smllpx-summary.htm

Home About Us Center Support Contact Us ... Chemical Terrorism BIOTERRORISM >> SMALLPOX OVERVIEW Printable Page Smallpox: Current, comprehensive information on pathogenesis, microbiology, epidemiology, diagnosis, treatment, and prophylaxis Last updated July 7, 2005 Agent Pathogenesis Epidemiology Occurrence of Smallpox in the Pre-eradication Era Global Eradication of Smallpox Reservoir/Modes of Transmission/Communicability Use of Smallpox as a Biological Weapon ... Clinical Features of Variola Minor Differential Diagnosis Differential Diagnosis of the Rash Illness Monkeypox Distinguishing Features Between Smallpox, Monkeypox, and Chickenpox Diagnostic Issues Criteria for Determining the Likelihood of Smallpox Laboratory Diagnosis Specimen Collection and Handling Laboratory Response Network (LRN) Tests for Detection and Identification of Variola Virus Rapid Tests for Diagnosis of VZV and HSV ... Treatment Smallpox Vaccination Historical Perspective Dryvax Vaccinia Vaccine New Vaccinia Vaccines Recommendations for Use of Vaccinia Vaccines ... References Agent Variola virus classification: DNA virus Family Poxviridae, subfamily Chordopoxviridae, genus

55. CNN.com - Germany Adopts Smallpox Measures - Dec. 20, 2002 CNN http://cnn.com/2002/WORLD/europe/12/20/germany.smallpox/index.html

CNN Europe CNN Asia Languages Spanish Portuguese German Italian Korean Arabic Japanese On CNN TV Transcripts Headline News CNN International ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Germany adopts smallpox measures Story Tools FACT BOX SMALLPOX: *There are two strains of smallpox: the less severe variola minor and the more deadly variola major *It is highly infectious, and has an incubation period of between seven and 17 days. *Symptoms include headache, delerium and vomiting, followed the development of the trademark rash *Patients are infectious with the onset of fever *The disease was eradicated in its natural form after a global mass vaccination campaign in the late 1970s *The duration of complete immunity provided by vaccination is believed to be less than 10 years BERLIN, Germany Germany is to increase its stocks of smallpox vaccine to enable it to protect the entire population of 82 million against a bioterrorist attack. Chancellor Gerhard Schroeder and state leaders agreed on launching the $119 million effort as fears grow over the possibility of smallpox been used by terrorists. Hans Martin Bury, a senior aide to Schroeder, told the Associated Press that Germany has stockpiled 35 million doses of smallpox vaccine and it will increase its reserve to 100 million under the new programme.

56. Vaccinia (Smallpox) Vaccine These revised recommendations regarding vaccinia (smallpox) vaccine update the In 1991, ACIP further expanded smallpox vaccination recommendations to http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5010a1.htm

Vaccinia (Smallpox) Vaccine Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2001 Advisory Committee on Immunization Practices Membership List, March 2001 CHAIRMAN John F. Modlin, M.D. Professor of Pediatrics and Medicine Dartmouth Medical School Lebanon, New Hampshire EXECUTIVE SECRETARY Dixie E. Snider, Jr., M.D., M.P.H. Associate Director for Science Centers for Disease Control and Prevention Atlanta, Georgia MEMBERS Dennis A. Brooks, M.D., M.P.H. Johnson Medical Center Baltimore, Maryland Richard D. Clover, M.D. University of Louisville School of Medicine Louisville, Kentucky Jaime Deseda-Tous, M.D. San Jorge Children's Hospital San Juan, Puerto Rico Charles M. Helms, M.D., Ph.D. University of Iowa Hospital and Clinics Iowa City, Iowa David R. Johnson, M.D., M.P.H. Michigan Department of Community Health Lansing, Michigan Myron J. Levin, M.D. University of Colorado School of Medicine Denver, Colorado Paul A. Offit, M.D. Children's Hospital of Philadelphia Philadelphia, Pennsylvania

57. CNN.com - Union Won't Oppose Smallpox Plan - Dec. 4, 2002 CNN http://cnn.com/2002/ALLPOLITICS/12/04/smallpox.vaccine/index.html

CNN Europe CNN Asia Languages Spanish Portuguese German Italian Korean Arabic Japanese On CNN TV Transcripts Headline News CNN International ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Union won't oppose smallpox plan Questions raised about vaccination Story Tools SPECIAL REPORT The hunt for al Qaeda Bin Laden's audio message, 2/03 Terror warning system Terror on tape ... War against terror WASHINGTON (CNN) Representatives of the nation's largest union of health care workers Wednesday said they will not oppose a government plan to vaccinate medical workers for smallpox, although they still have serious safety concerns about it. The announcement came after meeting with top federal health officials. President Bush is prepared to announce in coming days the first large-scale smallpox vaccinations in more than two decades a controversial plan because the vaccine can have serious side effects, including in rare cases death. Under the plan, about 500,000 health care workers will get the smallpox vaccination, followed up by a second wave of vaccinations for 7 million to 10 million other health workers, firefighters, police and first responders, according to a top government official. Andrew Stern, the president of the Service Employees International Union, which represents 1.5 million health-care workers, said union members will be encouraged to take the vaccine.

58. NIP: Smallpox/home Page smallpox National Immunization Program s smallpox subsite home page. http://www.cdc.gov/nip/smallpox/

Smallpox subsite Smallpox Home Public News Providers NIP: NIP HOME First time visitor? About NIP ... Acronyms NIP sub-sites: ACIP Flu Vaccine Immunization Registries Vaccines for Children Program ... VACMAN NIP Site Search National Immunization Hotline English Spanish TTY Get Adobe Reader Smallpox home page Smallpox The smallpox subsite has moved to CDC's Public Health Emergency Preparedness and Response Website If you are not automatically redirected click here National Immunization Program (NIP) NIP Home Contact Us Help Glossary ... Accessibility This page last modified on September 30, 2002 Department of Health and Human Services Centers for Disease Control and Prevention CDC Home CDC Search CDC Health Topics A-Z

59. Pediatricians Take Stand On Smallpox Vaccinations CNN http://cnn.com/2002/HEALTH/conditions/10/07/smallpox.pediatricians.ap/index.html

60. The Smallpox Protection Project Join the smallpox Protection Project by downloading the UD screensaver and help the earch for a cure to smallpox. http://www.chem.ox.ac.uk/smallpox/

The Smallpox Protection Project Introduction Smallpox was eliminated from the world in 1977 by a World Health Organization campaign. Despite this, stocks of the variola virus are known to exist and its use as a weapon of bioterrorism remains a frightening possibility. With vaccination having ended in 1972 the population is highly susceptible. The availability of drugs to counter the virus would be a major defence. There is a possible molecular target whose blockade would prevent the ravages of an infection, and we intend to use desktop grid computing to screen millions of potential anti-smallpox drugs against this target. This will involve the use of the United Devices Global Metaprocessor, which we have successfully used to target twelve proteins implicated in cancer and against an anthrax protein. The project can muster almost two million personal computers belonging to people in over two hundred countries, all of whom would benefit from protection against smallpox. News First big success for smallpox research project - Sept 2003 Join in by downloading the screensaver software.

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