61. Craniosynostosis Isolated sagittal synostosis (the suture that runs from the anterior fontanelleto the posterior fontanelle) occurs in about 55% of cases and isolated http://www.drhull.com/EncyMaster/C/craniosynostosis.html

Help for sleepless parents Encyclopedia Index C craniosynostosis Search craniosynostosis Craniosynostosis, or premature fusion of the skull plates, occurs in about one in 2,000 infants. It can be an isolated abnormality or part of a broader malformation syndrome The joints between the plates are called the sutures . Craniosynostosis occurs when for whatever reason, sporadic or as part of a larger problem, one or more of these sutures fuse prematurely. Constrained abnormally in one part of the skull, brain growth forces the remainder of the skull to expand out of proportion, leading to abnormal skull shape. Isolated sagittal synostosis (the suture that runs from the anterior fontanelle to the posterior fontanelle) occurs in about 55% of cases and isolated coronal suture synostosis (the suture that runs down laterally from the anterior fontanelle) occurs in 20% of cases. Diagnosis of craniosynostosis is by xrays, and increasingly by CT scan . Early evaluation and possible neurosurgical intervention is imperative, since the synostosis may be a marker for a larger pattern of abnormalities, and if synostosis is left uncorrected, head and facial shape can be severely affected. There is also concern that some forms of synostosis can cause damage to the infant brain by constraint of normal brain growth.

62. Anesthesiology - Fulltext: Volume 95(2) August 2001 P 340-342 Venous Air Embolis No episode of VAE was noted during the 19 sagittal synostosis repairs. With endoscopicrepair of metopic, coronal, and lambdoidal synostosis, a single skin http://www.anesthesiology.org/pt/re/anes/fulltext.00000542-200108000-00013.htm

LWWOnline LOGIN eALERTS REGISTER ... ASA Meeting Abstracts Venous Air Embolism during Endoscopic... ARTICLE LINKS: Abstract PDF (110 K) References (9) View full size inline images Anesthesiology Volume 95(2) August 2001 pp 340-342 Venous Air Embolism during Endoscopic Strip Craniectomy for Repair of Craniosynostosis in Infants Tobias, Joseph D. M.D.*; Johnson, Joel O. M.D., Ph.D.†; Jimenez, David F. M.D.‡; Barone, Constance M. M.D.§; McBride, D. Scott Jr., B.A.‖‖ * Professor, Departments of Anesthesiology and Pediatrics, † Associate Professor, Department of Anesthesiology, ‡ Associate Professor, Departments of Pediatrics and Neurosurgery, § Associate Professor, Departments of Pediatrics and Plastic Surgery, ‖‖ Medical Student, The University of Missouri. Received from the Department of Anesthesiology, The University of Missouri, Columbia, Missouri. Submitted for publication November 17, 2000. Accepted for publication February 15, 2001. Support was provided solely from institutional and/or department sources. Address correspondence to Dr. Tobias: The University of Missouri, Department of Anesthesiology, 3W40H, One Hospital Drive, Columbia, Missouri 65212. Address electronic mail to: TobiasJ@health.missouri.edu. Reprints will not be available from the authors. Individual article reprints may be purchased through the Journal Web site

63. Cranial Technologies, Inc., Manufacturer Of The DOC Band, An Following EndoscopicAssisted Craniectomy for sagittal synostosis This study the DOC Band® is used after endoscopic surgery for sagittal synostosis. http://www.cranialtech.com/ParentsArea/researcharticles.html

Discussion Board Photo Album Calendar Resources Decorating Parents' Pages Library News Articles Links If you would like a full copy of any of the articles below, please utilize our Contact Form to submit your request. Please include the article title and the journal name in your request. References About Positional Plagiocephaly View and obtain information about our comprehensive list of all research articles related to the subject of positional plagiocephaly. Car Seats, Infant Carriers, and Swings: Their Role in Deformational Plagiocephaly This study demonstrates the association of extended use of car seats, carriers, and swings and the development of deformational plagiocephaly. Littlefield TR, Kelly KM, Reiff JL, Pomatto JK; Journal of Prothestics and Orthotics July 2003; 15:3; 102-106. (pdf file) Is One Twin at Greater Risk? This study confirmed that the infant carried lower in the uterus was at greater risk for both plagiocephaly and torticollis. Littlefield TR, Kelly KM,Pomatto JK, Beals SP; Pediatrics (pdf file) News Release from AAP (online link) Diagnosis and Management of Positional Plagiocephaly A great A-Z summary of plagiocephaly, what causes it and treatment options. Written in lay terms with some wonderful handouts for repositioning and neck stretching exercises. Littlefield TR, Reiff JL, Rekate, HL.

64. Jayesh Panchal Francel P, Panchal J. Management of sagittal synostosis. sagittal synostosisPanel (Invited Lecture) American Cleft and Craniofacial Society Minnesota, http://jpanchal.com/resume.asp

CURRICULUM VITAE JAYESH PANCHAL Current Status: Associate Professor Chief, Section of Plastic Surgery University of Oklahoma Health Sciences Center Address: WP 2220 Section of Plastic Surgery 920 S.L.Young Blvd. Oklahoma City OK 73104 USA Telephone: Business: 405-271-4864 Home : 405-844- 9534 E-Mail: Business: jayesh-panchal@ouhsc.edu Home: jpanchal@cox.net Education: M.D. October 1978-84 Grant Medical College University of Bombay M.S. (Gen. Surg) July 1984-87 Grant Medical College University of Bombay Fellow Royal College Of Surgeons (General Surgery) May 1990 Royal College of Surgeons and Physicians of Glasgow Fellow Royal College Of Surgeons (General Surgery) June 1990 Royal College Of Surgeons of Edinburgh Fellow Royal College of Surgeons (Plastic Surgery) September 1990-95 Royal College of Surgeons of Edinburgh. Executive Health MBA May 2001 Major: Health University of Oklahoma GPA 3.8 Postgraduate Training: 8/1/90 to 5/31/91 Junior Resident, Plastic Surgery, Leicester Royal Infirmary, Leicester, England 6/1/91 to 5/31/92 Junior Resident, Plastic Surgery, Kingston General Hospital, Hull, England

65. Genes At Work - Topics In Genetics sagittal synostosis is most commonly diagnosed and represents over 50% of thesynostoses. This type of synostosis results in a dolicocephalic head shape http://www.umdnj.edu/genesatwork/topics/pediatrics/02_pediatrics.htm

Craniosynostoses: Genetic Considerations by Beth A. Pletcher, MD, May 1999 In addition to simple synostosis, there are over 75 syndromes described where craniosynostosis is a feature. When craniosynostosis occurs in the context of growth retardation, multiple congenital anomalies and/or mental retardation, one should always consider a cytogenetic cause. For example, metopic suture synostosis is quite common in deletion 9p which is also associated with dysmorphic facial features and developmental delay. A cloverleaf cranial deformity is a severe defect resulting in a trilobular head shape and is seen in both thanatophoric dysplasia and two subtypes of Pfeiffer syndrome. Recent advances in molecular genetics have greatly expanded our understanding of some of the more well known syndromic craniofacial syndromes. While in the past patients have been categorized by clinical features alone, the discovery of several "craniofacial genes" in recent years has forced clinicians to rethink their diagnostic approach. It has been shown that mutations (genetic typos) within the same gene can result in several different craniofacial syndromes. Furthermore, mutations in different genes can also result in the same collection of clinical features and identical diagnoses. In order to put this in perspective, it may be useful to review some of the more common craniofacial disorders and their clinical descriptions.

66. Dylan Baby with sagittal synostosis. Dylan was diagnosed with sagittal synostosiswhen he was ten days old. His surgery is tenatively scheduled for November http://kidsneedprayer.net/dylan.html

DYLAN Had surgery on Oct 20, 2003! Doing well! - Keep praying! Parents: Sisters: Haley and Caleigh City/State: New Mexico Diagnosis: Sagittal Synostosis Age: 4 Months Old Birthday: July 13, 2003 E-Mail: WEB URL: Remarks: 1st PRAYER REQUEST: Date Dylan was diagnosed with Sagittal Synostosis when he was ten days old. His surgery is tenatively scheduled for November of 2003. I would like to have information on Sagittal Synostosis. God bless, Elaine Update: I just spoke with Mom Elaine, and she told me that his surgery was on October 20, 2003, and that he is doing well. Please continue to pray for Dylan's complete healing, and his protection. God bless, Grampa Jim NOTE: WITHOUT PERMISSION OF THE AUTHORS Some materials used by permission of their respective authors

67. Ashley Diagnosis sagittal synostosis (No soft spot in skull to allow it to expand I believe the condition is called sagittal synostosis and you can click the http://kidsneedprayer.net/ashley.html

ASHLEY SHE IS DOING WELL!! Parents: Brother: C. J. City/State: Indiana Diagnosis: Sagittal Synostosis (No soft spot in skull to allow it to expand with growth) Age: 2 Years Old Birthday: July 25, 2002 Contact : Martha E-Mail: thepromise@comcast.net WEB URL: none Remarks: 1st PRAYER REQUEST: Date Ashley - about one year old- Her grandparents are Terry and Martha. Ashley will have major surgery on Feb 28 at Riley Hosp in Indy. She was born WITHOUT a soft spot on the top of her head. She's developmentally on target for growth without any known delays or problems. However, her brain is growing, protruding her forehead outward. So a team of neurosurgeons and plastic surgeons plan to correct this defect. PLEASE uphold this little one in your prayers AS WELL AS THE family. We know that THE GREAT PHYSICIAN will be with this team of doctors. May the family feel His presence. PRAISE REPORT Hi Jim, Martha PRAISE REPORT Dear grandpa Jim, Thanks again, Ashley's grandma (Martha) God Bless YOU ALL! PRAISE REPORT I just spoke with Ashley's grandmother, and she said that Ashley came home Tuesday nite, 03-04-03, and that she is doing great!! They said that she is laughing and smiling, and pretty much acting normally! The surgery went very well, and she will not need any more!

68. Blackwell Synergy - Cookie Absent Postoperative morphology of the CNS in sagittal synostosis differs substantially Posnick J, Armstrong D, Bite U (1995) Metopic and sagittal synostosis http://www.blackwell-synergy.com/doi/abs/10.1111/j.1469-7580.2005.00397.x

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69. Abstracts Of Staff Publications Twelve patients with sagittal synostosis underwent correction between 8 months While optimal treatment for sagittal synostosis may be obtained in the http://www.childsdoc.org/fall96/abstracts.asp

Home Departments Abstracts Features Departments Information ... Contact us Abstracts of staff publications Late Correction of Sagittal Synostosis in Children Jay Pensler, Stanley Ciletti, Tadanori Tomita From the Divisions of Plastic Surgery and Neurosurgery at the Northwestern University Medical School and Children’s Memorial Hospital, Chicago. Plastic and Reconstructive Surgery Tumor Angiogenesis Correlates with Metastatic Disease, N- myc Amplification, and Poor Outcome in Human Neuroblastoma Dafna Meitar, Susan Crawford, Alfred Rademaker, and Susan Cohn From the Departments of Pediatrics and Pathology, Children’s Memorial Hospital; and the Biometry Section, Robert Lurie Cancer Center, Northwestern University Medical School, Chicago. Journal of Clinical Oncology Purpose : To determine if the clinical outcome of children with neuroblastoma (NB) is correlated with the degree of tumor neovascularization and to assess the relationship of stage, N- myc copy number, and histology to angiogenesis. Materials and Methods : The vascularity of primary untreated NB from 50 patients diagnosed at a single institution between 1984 and 1994 was evaluated. An image processor was used to analyze the tumor tissue area for each histologic slide of tumor, and a vascular index (VI) was calculated, where VI = total number of vessels/mm[2] of tissue area. Tumors were classified histologically according to the criteria of Shimada et al (

70. Speech Pathology Online: Review Board Member: Lynn Marty Grames, B.Sc. Language and Phonological Disorder in sagittal synostosis A Preliminary Report SpeechLanguage Disorder in Non-Syndromic sagittal synostosis , http://www.speechpathology.com/our_company/rvwboard_detail.asp?abid=33

71. Clinical Dysmorphology - UserLogin The patient described presented with SOD, sagittal synostosis, osteoporosis, anddental abnormalities. SOD has been described in association with a number http://www.clindysmorphol.com/pt/re/mcd/fulltext.00019605-200304000-00006.htm

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72. Sagittal Synostosis (scaphocephaly) Charles Davis is a Plastic, Reconstructive and CranioMaxillofacial Surgeon.He specialises in treating craniofacial malformations and complex ear and http://www.craniofacialsurgery.co.nz/scaphocephaly.html

Sagittal synostosis (scaphocephaly) If detected early enough, I correct scaphocephaly using a spring assisted cranioplasty . After 9 months of age a modified pi-plasty is used. Back to page Craniofacial Surgery Ear Reconstruction Maxillofacial Surgery ... Skin Cancer

73. Treatment Of Craniofacial Disorders At Mayo Clinic In Rochester sagittal synostosis (scaphocephaly) skull is long and narrow. MetopicSynostosis (trigonocephaly) pointed forehead. Coronal Synostosis (plagiocephaly) http://www.mayoclinic.org/pediatrics-rst/craniofacial.html

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Specialties Pediatrics Pediatrics Overview Patient Stories Diseases, Treatments and Services Appointments ... Other Specialties - Rochester Treatment of Craniofacial Disorders in Children The treatment of children with craniofacial disorders requires a comprehensive team approach. The combined expertise of the multidisciplinary Mayo Clinic craniofacial disorders team optimizes the holistic care of the child. The team includes specialists from Pediatric Neurosurgery, Plastic and Reconstructive Surgery, Child and Adolescent Neurology and Pediatric Medical Genetics. This team has the most current diagnostic and treatment options available. Symptoms Premature closure of growth plates in the skull cause abnormal growth patterns of the face and skull. The altered growth results in an abnormal head shape. The actual shape of an affected infant's head depends on which growth plates closed prematurely. An infant's skull is made up of a collection of separate bones. The spaces between these bones are called sutures. The brain grows rapidly in an infant. In order to make room for the growing brain, the skull also grows rapidly. Growth of the skull takes place at the sutures. Premature fusion or closure of these sutures is called craniosynostosis . In a child with craniosynostosis, the brain continues to grow. However, the skull will not grow where the suture is closed. Compensatory growth occurs at adjacent sutures, resulting in an abnormal head shape.

74. UAMS Plastic Surgery - Publications Synostectomy Versus Complex Cranioplasty for the Treatment of sagittal synostosis . Undergoing the Pi Procedure for Correction of sagittal synostosis. http://www.uams.edu/dps/publications.htm

Plastic Surgery Faculty Division Publications James C. Yuen: Hand Surgery Certification in the United States (Letter to the Editor). Yuen JC. J Hand Surgery (American Volume) The Versatility of the Purse-string Suture in Wound Closure. Yuen JC. Plastic and Reconstructive Surgery, Double Skin Paddle Fibular Flap for a Through-and-Through Oromandibular Defect. Yuen JC, Zhou A, and Shewmake K. Annals of Plastic Surgery, 1996; 37 (1): 111-115 . Free Flap Coverage for Knee Salvage. Yuen JC and Zhou A. Annals of Plastic Surgery, 1996;37:158-166. Free Muscle Flap Coverage of Exposed Knee Joints Following Fulminant Meningococcemia. Yuen JC. Plastic and Reconstructive Surgery, 1997;99(3): 880-884. Kris Shewmake: Synostectomy Versus Complex Cranioplasty for the Treatment of Sagittal Synostosis. Boop FA, Shewmake K, Chadduck W. Child's Nerv Syst, 1996;12:371-375. Outcome Analysis of 85 Patients Undergoing the Pi Procedure for Correction of Sagittal Synostosis. Boop FA, Chadduck WM, Shewmake K, Teo C. J Neurosurg, 1996;85:50-55

75. CCDD: Family: References: Links: Craniosynostosis Conditions sagittal synostosis Home Page, Skull is long and narrow Scaphocephaly.sagittal synostosis Homepage, Scaphocephaly, dolicocephaly, sagittal craniostenosis http://www.hopkinsmedicine.org/craniofacial/References/LinkList.cfm?Category=Fam

76. Pediatric Cranial Synostosis sagittal synostosis causes elongation and narrowing of the skull that can attaingrotesque proportions in childhood and are only partly mitigated by normal http://www.ohsu.edu/neurosurgery/conditions/synostosis.shtml

What is Neurosurgery? Informational videos John Raaf Day Lecture Neurosurgical Services Brain Tumor Cerebrovascular Epilepsy Facial Pain ... Surgical Technology Community Community Neurosurgery Patient Services Appointments Insurance and Billing In the News News Make A Gift Have a Question? Home Department of Neurological Surgery at OHSU Patient Information - Pediatric Cranial Synostosis Premature ossification of a suture, or synostosis, is sometimes attributed to intrauterine restraint of head growth by twinning or by early engagement of the head in the pelvis. It is commonly seen in craniofacial disorders such as Crouzon, Apert, Pfeiffer, or Saethrre-Chotzen syndromes, or in the setting of fetal exposure to phenytoin, valproic acid, or other teratogens. Most often, however, there is no identifiable cause. Sporadic cases typically involve a single suture; syndromic cases typically demonstrate more complex, multi-sutural involvement, often bilateral coronal synostosis. The expansion of the head is driven from within by growth of the brain, and craniosynostosis causes deformity by restricting expansion of the head in the dimension perpendicular to the affected suture. Compensatory pressure by the growing brain results in expansion, or bossing, in adjacent areas of the skull. The characteristic patterns of deformity caused by synostosis of each individual suture are readily recognized by the trained eye. Thus, physical examination is the gold standard for evaluation of this problem.

77. Sahlgrenska Universitetssjukhuset - SU - Claes Lauritzen Friede H, Lauritzen C sagittal synostosis I. Preoperative Skull Morphology . Hermann N, Kreiborg S, Friede H, Lauritzen C sagittal synostosis II. http://www.sahlgrenska.se/vgrtemplates/Page____14860.aspx

Hj¤lp och service Kontakt Hem In English Om du blir sjuk F¶rlossningsv¥rd Patient och anh¶rig Hitta r¤tt p¥ SU ... V¥rdgivarinfo Tillbaka Sahlgrenska Universitetssjukhuset Avdelning 37 Avdelning 41 Broschyrer ... Universitetsdel Claes Lauritzen Befattning : Professor, Docent, –verl¤kare, Chef f¶r Kraniofaciala enheten Forskningsomr¥de : Kraniofacial kirurgi Examen : M.D., Ph.D. Telefon Fax E-post (OBS - Ej f¶r patienter) Bibliography 1. Lauritzen, C. A new and easier way to anastomose microvessels: An experimental study in rats. Scand J Plast Reconstr Surg 1978;12:291. An experimental study in rats. Scand J Plast Reconstr Surg 1979;13:417, 1979. The sleeve anastomosis in clinical microsurgery. Case reports. Scand J Plast Reconstr Surg 1979;13:477. 5. Lauritzen, C. The microvascular sleeve anastomosis. Thesis. Medicinska fakulteten, G¶teborgs universitet. 6. Lauritzen, C. Wound healing of the microvascular sleeve anastomosis. I Symposium on Wound Healing (ed. B¶rje Sundell), ESPO, sid 125-131. An experimental study in rabbits. Scand J Plast Reconstr Surg 1981;15:5. An experimental study in rabbits. Scand J Plast Reconstr Surg 1981;15:93.

78. Neurosurgery Programs | UBC Surgery Children with sagittal synostosis are operated on by a neurosurgeon alone, whereasthose with coronal or metopic synostosis are operated on asa team http://www.surgery.ubc.ca/neuroprograms.html

Home Divisions Education Research ... Rounds Programs: Neurosurgery Home Faculty Rounds/Events Conferences ... Programs Links on this page: Comprehensive Pediatric Epilepsy Surgery Program Spina Bifida Program Motor disorders/spasticity Rhizotomy Program ... Craniosynostosis Comprehensive Pediatric Epilepsy Surgery Program The Comprehensive Epilepsy Surgery Program was established in 1992 and is led by pediatric neurologist Dr. Mary Connolly. There is a large multidisciplinary team, including multiple neurologists, neuropsychologists, psychologists, radiologists, nurses, electrophysiologists and electrophysiology technologists, in addition to neurosurgeons. The neurosurgeons on the epilepsy surgical team comprise Dr. Steinbok and Dr. Price . From 1992 until the end of 2001, we have operated on 100 children for intractable epilepsy. The procedures have included temporal lobectomies, extratemporal cortical resections, hemispherectomies or hemispherotomies, subpial transections, corpus callosotomies and implantation of vagal nerve stimulators. In 18 of the 100 children with epilepsy surgery we have made use of monitoring directly from the surface of the brain, using subdural grids and strips of electrodes. Our results compare favorably with what has been reported from other major centers around the world. The most common epilepsy surgery procedure has been a temporal lobectomy, with 25 such cases. Of these 25 children, 19 (82%) are seizure free, 4 are significantly improved and only 2 (8%) have not been improved. For extratemporal cortical resections, the results, as in other centers are not as good, with 50% of patients, being seizure free. However, patients with frontal lobe epilepsy have done better as a group, with 69% being seizure free. We have done 18 hemispheric operations up to December 2001, and 14 of these 18 children (77%) are seizure free.

79. Portal Toolkit Invalid Site URL The management of sagittal synostosis, however, has undergone A male childwho underwent correction of his sagittal synostosis at 6 months of age. http://ppv.ovid.com/pt/re/aunz/fulltext.00130494-200311000-00024.htm

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80. Portal Toolkit Invalid Site URL Pre and postoperative developmental attainment in sagittal synostosis Aims To investigate whether sagittal synostosis (SS) has consequences for http://ppv.ovid.com/pt/re/adch/fulltext.00000740-200504000-00008.htm

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