Rabies on the Rise by Audrey T. Hingley After years of decline in America, a form of viral encephalitis transmitted through infected animal saliva is on the rise. The life-threatening disease is rabies. According to John Krebs, a public health scientist with the Centers for Disease Control and Prevention, rabies cases in animals increased dramatically between 1990 and 1993. In 1990 there were 4,880 reported animal deaths from rabies; that figure jumped to 9,495 three years later. With treatment, human deaths from rabies are rare in the United States. One death in 1990, three deaths in 1991, one death in 1992, and three deaths in 1993 were recorded, with six people dying in 1994 and four in 1995 from the disease. Charles Rupprecht, V.M.D., Ph.D., chief of CDC's rabies section, says education is the key to preventing the disease. Rupprecht says only one inadequately treated person is known to have recovered completely from rabies and escaped death. "In 1970 Matthew Winkler was exposed [to rabies], treated [with postexposure vaccine], and because vaccines were not as good then, experienced a vaccine failure. He recovered despite the vaccine failure, which is a far different thing than catching the disease, [not being treated,] and recovering," he points out. "Some people question to this day whether that case meets all the criteria [of a human known to survive rabies without treatment]." Over the years, scientists have improved both the effectiveness and safety of human rabies vaccines, regulated by the Food and Drug Administration as biologics. Today's vaccines are highly effective and produce few side effects. They work by causing the immune system to produce antibodies that neutralize the rabies virus before it causes the disease. Unlike most vaccines, which are given before disease exposure occurs, rabies vaccine is usually administered after someone has been exposed to the disease. A preexposure vaccine series designed for people considered high-risk for exposure to rabiessuch as veterinarians, researchers, forest rangers, animal control officers, cave explorers, animal handlers, or those who spend time in countries where rabies is prevalentis also available. | |
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