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         Primary Progressive Aphasia:     more detail
  1. Primary Progressive Aphasia
  2. False recognition of incidentally learned pictures and words in primary progressive aphasia [An article from: Neuropsychologia] by E. Rogalski, D. Blum, et all 2007-01
  3. Number words are special: Evidence from a case of primary progressive aphasia [An article from: Journal of Neurolinguistics] by F. Domahs, L. Bartha, et all
  4. Category and letter fluency in semantic dementia, primary progressive aphasia, and Alzheimer's disease [An article from: Brain and Language] by C.A. Marczinski, A. Kertesz, 2006-06-01

61. Rare Diseases Terms - Office Of Rare Diseases
PPA syndrome. Aphasia, primary progressive. PPA. Nonfluent primary progressiveaphasia. Information about primary progressive aphasia is available from
http://ord.aspensys.com/asp/diseases/diseaseinfo.asp?ID=8541

62. HighWire -- Browse Journals - Primary Progressive Aphasia
Browse Journals publishing on primary progressive aphasia, (return to Topic Listpage Alphabet, , Frequency of articles in primary progressive aphasia
http://highwire.stanford.edu/lists/topic_dir/608683/608684/615510/615597/615681/
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Sort by: Alphabet Frequency of articles in Primary Progressive Aphasia Focus of journal on Primary Progressive Aphasia What's this? Journals focusing on Primary Progressive Aphasia (in order by highest focus) New England Journal of Medicine info Brain info ... Delirium, Dementia, Amnestic, Cognitive Disorders Primary Progressive Aphasia Home Adv. Search For Institutions For Publishers ... partners/suppliers

63. JNNP -- Sign In Page
Context Patients with primary progressive aphasia have sentence comprehensiondifficulty, The pathology and nosology of primary progressive aphasia.
http://www.jnnp.com/cgi/content/full/76/5/644

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A longitudinal study of sentence comprehension difficulty in primary progressive...
Grossman and Moore J Neurol Neurosurg Psychiatry.
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64. Personal Profile
primary progressive aphasia A tutorial. Acquiring Knowledge in Speech, Language and Impairmentbased interventions in primary progressive aphasia
http://www.maccs.mq.edu.au/people/profile.htm?ID=92600905&Status=22

65. CBU Bibliography
Title Semantic dementia and primary progressive aphasia a problem of Key Words aphasia, dementia, semantic dementia, primary progressive aphasia,
http://www.mrc-cbu.cam.ac.uk/cgi-bin/biblio.cgi?author=Knibb J&abstract=on

66. Dr Karen Croot
Croot, K. (2000) primary progressive aphasia A tutorial. Acquiring Knowledge inSpeech, Language and Hearing, 2, 9092. Croot, K., Hodges, JR, Xuereb, J.,
http://www.psych.usyd.edu.au/staff/karenc/

67. Aphasia Center Of California
My family member was recently diagnosed with primary progressive aphasia. primary progressive aphasia (PPA) differs from aphasia following stroke.
http://www.employees.org/~accadmin/answers.html
How do I attend Aphasia Center of California programs? The first step in being admitted into our programs is to call the Aphasia Center of California at (510) 336-0112. During this phone call, we will gather information including relevant medical history and the current severity and type of aphasia. We will also determine which of our treatments or classes are of most interest to the person with aphasia. An appointment will then be made for an initial visit to our program. I have a family member with aphasia who lives outside of the Northern California area. Can we come to the Aphasia Center of California for a few months of treatment? The Aphasia Center of California's community based programs are designed to provide long term treatment and support for all those affected by aphasia. We recommend that individuals who attend our programs live nearby for at least a 4 month time period so that they can experience the benefit of group communication treatment. How long can I continue to make progress following my stroke?

68. American Journal Of Alzheimer S Disease And Other DementiasAbstracts
primary progressive aphasia A review of the neurobiology of a common primary progressive aphasia (PPA) is an identifiable and distinct form of clinical
http://pnpcsw.pnpco.com/cadmus/testvol.asp?journal=alz&year=2002

69. Cognitive And Behavioral Neurology - Abstract: Volume 17(4) December 2004 P 185-
Study of Behavior in Frontotemporal Dementia and primary progressive aphasia . variant of FTD (FTDbv) and 14 with primary progressive aphasia (PPA).
http://www.neuneubeneu.com/pt/re/cbneuro/abstract.00146965-200412000-00001.htm
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PDF (96 K) A Longitudinal Study of Behavior in Frontotemporal Dementia and Primary Progressive Aphasia.
Marczinski, Cecile A. PhD; Davidson, Wilda BEd; Kertesz, Andrew MD, FRCPC Abstract:
Objective: To evaluate the construct validity of the Frontal Behavioral Inventory (FBI) and to describe the evolution of the behavioral abnormalities of the behavioral and aphasic presentations of frontotemporal dementia (FTD) by means of a 3-year longitudinal study. Background: The FBI is a standardized behavioral questionnaire useful in the diagnosis and quantification of the personality and behavior disorder FTD. Method: Patients who had three consecutive yearly assessments with the FBI were selected, 12 with the behavioral variant of FTD (FTD-bv) and 14 with Primary Progressive Aphasia (PPA). Results: FBI scores rose as the disease progressed in both the FTD-bv and PPA groups over the 3 years of testing. Initial mean FBI scores of the FTD-bv group were above the cutoff for FTD as established for this diagnosis with previous standardization. By the third year, the mean FBI score of PPA patients was also above the established cutoff for FTD. Conclusions: The outcome of the study demonstrates that the FBI is sensitive to changes in behavior and personality in both variants of FTD. The FBI can be used to describe the evolution of symptoms and the course of the illness of Pick complex patients who present initially with FTD-bv or who present with PPA and subsequently develop the behavioral disorder.

70. Cognitive And Behavioral Neurology - UserLogin
primary progressive aphasiadifferentiation from Alzheimer s disease. Ann Neurol . The pathology and nosology of primary progressive aphasia. Neurology.
http://www.neuneubeneu.com/pt/re/cbneuro/fulltext.00146965-200412000-00001.htm
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71. Publications List For Researcher
Managing primary progressive aphasia. (Invited article). Primary progressiveaphasia. An uncommon masquerader of psychiatric disorders.
http://mayoresearch.mayo.edu/mayo/research/staff/publications-listed.cfm?personi

72. Websites & Resources
Treatment of primary progressive aphasia at Mayo Clinic in Rochesterhttp//www.mayoclinic.org/pparst/index.html. Association for Frontotemporal Dementia
http://mayoresearch.mayo.edu/mayo/research/alzheimers_center/resources.cfm
research staff
Faculty
more pages
Jacksonville Clinical Research Neuroimaging Services
clinical trials
See our clinical trials
http://www.mayoclinic.org/alzheimers-rst/index.html

http://www.alz.org/

http://www.alzmndak.org/
...
http://www.alzheimers.org/
Alzheimer Web
http://www.alzweb.org
NINDS Alzheimer's Disease Information Page
http://www.ninds.nih.gov/health_and_medical/disorders/alzheimersdisease_doc.htm

http://mayoresearch.mayo.edu/mayo/research/alzheimers_center/

http://mayoresearch.mayo.edu/mayo/research/mcj/neuroscience.cfm
American Academy of Neurology (AAN) Guidelines
http://www.aan.com/professionals/practice/pdfs/dem_pat.pdf

http://www.thebrainmatters.org/alzheimers.htm

http://www.alzheimers.org/pubs/genefact.html
http://www.alzheimers.org/pubs/conv10n3and4.pdf ... http://www.aan.com/professionals/practice/pdfs/gl0070.pdf
Dementia
Counselling ANd Diagnosis in Dementia (CANDID) http://193.62.68.10/candid/ Dementia Web http://dementia.ion.ucl.ac.uk/ CNS Degenerative Disease - Neuropathology http://www-medlib.med.utah.edu/WebPath/TUTORIAL/CNS/CNSDG.html
Clinical Trial Websites
www.clinicaltrials.gov

73. Pick's Disease Fact Sheet
In primary progressive aphasia, the disease starts in an area at the back of thefrontal lobes and front of the temporal lobes. What are the Symptoms?
http://www.angelfire.com/ia/dougkeck/picksinfo.html
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Pick's Disease Fact Sheet
(frontotemporal lobar degeneration)
Information for PDSG booklet
What is it?
A progressive dementia occurring in middle life characterised by slowly developing changes in character and social behaviour, or impairment of language, due to degeneration of the frontal and temporal lobes of the brain.
Where does the name come from?
Arnold Pick was the doctor who was the first to describe the disease in 1892.
Other names for the disease
Many doctors now prefer to reserve the name "Pick's" for just one of the types of changes in the brain tissue (histology) that may be seen with the disease. You may come across several different names which are explained below: Frontotemporal lobar degeneration, frontotemporal dementia, semantic dementia and primary progressive aphasia.
Frontotemporal lobar degeneration
Many doctors now prefer this name for the disease. Patients who would have previously been told they had Pick's Disease may now be told they have frontotemporal lobar degeneration. The name refers to the parts of the brain that are affected: the frontal and temporal lobes (at the front and side of the brain respectively).

74. A Case Of Primary Progressive Aphasia. A 14-year Follow-up Study With Neuropatho
primary progressive aphasia has been clinically defined as a progressive languagedeficit leading to the dissolution of almost all language functions with
http://brain.oxfordjournals.org/cgi/content/abstract/121/1/115
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ARTICLES
A case of primary progressive aphasia. A 14-year follow-up study with neuropathological findings
M Schwarz, R De Bleser, K Poeck and J Weis
Department of Neurology, RWTH Aachen, Germany. Primary progressive aphasia has been clinically defined as a progressive language deficit leading to the dissolution of almost all language functions with relative preservation of other cognitive functions until late in the course of the disease. Two types of language impairment have been described for primary progressive aphasia, which differ with respect

75. Heterogeneity In Progressive Aphasia Due To Focal Cortical Atrophy. A Clinical A
primary progressive aphasia A LanguageBased Dementia Patterns of CerebralAtrophy in primary progressive aphasia Am. J. Geriatr.
http://brain.oxfordjournals.org/cgi/content/abstract/113/5/1321
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Request Permissions PubMed PubMed Citation Articles by Tyrrell, P. J. Articles by Rossor, M. N.
ARTICLES
Heterogeneity in progressive aphasia due to focal cortical atrophy. A clinical and PET study
PJ Tyrrell, EK Warrington, RS Frackowiak and MN Rossor
MRC Cyclotron Unit, Hammersmith Hospital, London, UK. Six patients with a slowly progressive aphasic disorder due to degenerative cortical disease are reported. The length of history varied from 18 months to 6 years. In 5 patients, there was a naming deficit, associated in 4 of these with some abnormalities in comprehension. One patient had a progressive history of reduced speech output, which was associated with an

76. Colin David Field
primary progressive aphasia Serial neurolinguistic, neuropsychological andradiological primary progressive aphasia A case study over five years.
http://www.psychology.adelaide.edu.au/members/external/colinfield/colinfield.htm

77. J.B. Orange
primary progressive aphasia The future of neurolinguistic and biologic Pragmatics in frontal lobe dementia and primary progressive aphasia.
http://faculty.arts.ubc.ca/graham/orange.htm
J.B. Orange
Dr. J.B. Orange is an Associate Professor in the School of Communication Sciences and Disorders at the University of Western Ontario, London Ontario Canada. He graduated from Queen's University at Kingston Ontario with a Bachelor of Science degree in Life Sciences. He completed his graduate work in speech-language pathology at the University of Toronto and his doctoral education at the State University of New York at Buffalo. He completed a post-doctoral research fellowship from the R. Samuel McLaughlin Centre for Gerontological Health Research at McMaster University at Hamilton Ontario. During his post-doctoral fellowship he completed several studies on the communication and discourse of individuals with Alzheimer's disease.
His peer-reviewed publications and funded research address language and cognitive-communication disorders of adults and older adults. His research has a special emphasis on discourse, conversation, and pragmatic analyses of individuals with various forms of dementia. Current research projects include the analyses of language, discourse, conversation, and pragmatics of individuals with Alzheimer's disease, frontal lobe dementia, and primary progressive aphasia. Other on-going studies include communication enhancement education and training programs for caregivers of individuals with dementia.
Publications
Peer-Reviewed
Peer-Reviewed (Invited): Special Issues
Books, Monographs, and Chapters

78. Honolulu Star-Bulletin News /2005/06/23/
An article on primary progressive aphasia in the New England Journal of Medicine The most common sign of primary progressive aphasia is the inability to
http://starbulletin.com/2005/06/23/news/story10.html

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Thursday, June 23, 2005

of medicine resigns
A neuro-degenerative
disorder ends an
accomplished tenure
By Helen Altonn
haltonn@starbulletin.com
Dr. Edwin Cadman, who has been on leave since February as dean of the John A. Burns School of Medicine, will return to the school Aug. 8 as a professor. STAR-BULLETIN / 2004 Dr. Edwin Cadman, who resigned yesterday as dean of the John A. Burns School of Medicine, has been a strong booster for the school as an economic pump for state biotechnology. He resigned from the dean's position yesterday after six years because of a neuro-degenerative disorder called primary progressive aphasia. Cadman explained his condition in an emotional appearance before the University of Hawaii Board of Regents. "I cannot talk clearly but I remember everything," Cadman told the regents. He said he has been blessed the past few months "with the outpouring of support not only by my friends, but by strangers as well. I want to thank them all for their cards, letters, e-mails and prayers. I want to especially thank the students, faculty and staff of the medical school who were so kind to me." Cadman's disorder, previously undisclosed, is a form of dementia that interferes with verbal expression and language comprehension. People do not lose their memory with aphasia as they do with Alzheimer's, the more common form of dementia, but they have language dysfunction, said Dr. Cherylee Chang, neurologist and medical director of the Queen's Medical Center's Neuroscience Institute. There is no effective treatment.

79. The Pathology And Nosology Of Primary Progressive Aphasia -- Kertesz Et Al. 44 (
We present three cases of primary progressive aphasia (PPA) with Pick variantpathology to Patterns of Cerebral Atrophy in primary progressive aphasia
http://www.neurology.org/cgi/content/abstract/44/11/2065
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ARTICLES
The pathology and nosology of primary progressive aphasia
A Kertesz, L Hudson, IR Mackenzie and DG Munoz
Department of Clinical Neurological Sciences, St. Joseph's Hospital, London, ON, Canada. We present three cases of primary progressive aphasia (PPA) with Pick- variant pathology to support a hypothesis of an underlying nosologic relatedness. Neuropathologic examination demonstrated focal brain atrophy with corresponding neuronal loss and gliosis, accompanied by superficial spongiosis. Specific histologic findings were ballooned neurons (Pick

80. Primary Progressive Aphasia With Focal Neuronal Achromasia -- Lippa Et Al. 41 (6
primary progressive aphasia A LanguageBased Dementia N. Engl. J. Med., October16, 2003; 349(16) 1535 - 1542. Full Text PDF
http://www.neurology.org/cgi/content/abstract/41/6/882
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ARTICLES
Primary progressive aphasia with focal neuronal achromasia
CF Lippa, R Cohen, TW Smith and DA Drachman
Department of Neurology, University of Massachusetts Medical Center 01655. We describe the clinical, radiologic, neuropsychological, and neuropathologic features of a 69-year-old man with a 3-year history of progressive transcortical expressive aphasia. Neuropsychological testing showed progressive dysfunction of expressive language. Neuropathologic examination demonstrated focal cortical degeneration involving the left superior frontal gyrus, with swollen achromasic neurons and no evidence of

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