41. PRIMER PROGRESIF AFAZI primary progressive aphasia has been clinically defined as progressive languagedeficit The pathology and nosology of primary progressive aphasia. http://med.ege.edu.tr/norolbil/2000/NBD08300.html

42. Healthy Living - June Is National Aphasia Awareness Month primary progressive aphasia is not Alzheimer s disease. Most people with primaryprogressive aphasia maintain ability to take care of themselves, http://www.healthierliving.org/newsletter/200206/aphasia.html

Join our discussions! Search the Healthy Living Web Site Advanced Search This Week's Discussion Topics Home Message Board About Us Alternative ... Contact Us June is National Aphasia Awareness Month What is aphasia? Aphasia is an acquired disorder caused by brain damage which affects a person's ability to communicate. The principal signs of aphasia are impairments in the ability to express oneself when speaking, trouble understanding speech, and difficulty with reading and writing. Aphasia is most often the result of stroke or head injury, but can also occur in other neurological disorders, such as brain tumor or Alzheimer's disease. The effects of aphasia differ from person to person, and can sometimes benefit from speech therapy. Strategies to communicate non-verbally (without words) may also be helpful to the person with aphasia. What is primary progressive aphasia? The syndrome of primary progressive aphasia has been defined by Mesulam and colleagues as a progressive disorder of language, with preservation of other mental functions and of activities of daily living, for at least two years. Primary progressive aphasia is not Alzheimer's disease. Most people with primary progressive aphasia maintain ability to take care of themselves, pursue hobbies, and, in some instances, remain employed. The problem is a disorder of language; and signs and symptoms of other clinical syndromes are not found through tests routinely used to determine the presence of other conditions. Although primary progressive aphasia may take a number of forms, it commonly appears initially as a disorder of speaking (an articulatory problem), progressing to nearly total inability to speak in its most severe stage, while comprehension remains relatively preserved. A less common variety begins with impaired word finding and progressive deterioration of naming and comprehension, with relatively preserved articulation.

43. Alzheimer Disease And Associated Disorders - UserLogin Monozygotic Twins Discordant for primary progressive aphasia Primary progressiveaphasia (PPA) is a clinical syndrome characterized by progressive http://www.alzheimerjournal.com/pt/re/adad/fulltext.00002093-200401000-00012.htm

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44. Alzheimer Disease And Associated Disorders - Abstract: Volume 17(2) April/June 2 April/June 2003, 172 Familial primary progressive aphasia. Summary Primaryprogressive aphasia (PPA) is a neurodegenerative disease presenting with http://www.alzheimerjournal.com/pt/re/adad/abstract.00002093-200304000-00009.htm

LWWOnline LOGIN eALERTS REGISTER ... Archive Familial Primary Progressive Aphasia. ARTICLE LINKS: Fulltext PDF (565 K) Permissions Familial Primary Progressive Aphasia. Krefft, Thomas A. *; Graff-Radford, Neill R. *; Dickson, Dennis W. *; Baker, Matt +; Castellani, Rudy J. ++ Abstract: Subscribe to RSS feed utrdc-pt01 Release 4.0

45. Primary Progressive Aphasia primary progressive aphasia Article in German Block F, Kastrau F. primary progressive aphasia is a rare disease characterised by slow deterioration http://www.malattiemetaboliche.it/articoli/aphasia.htm

Nervenarzt. 2004 Jul 15 [Epub ahead of print] Related Articles, Links [Primary progressive aphasia] [Article in German] Block F, Kastrau F. Neurologische Klinik UK Aachen. Primary progressive aphasia is a rare disease characterised by slow deterioration of language, which remains the leading symptom whereas other cognitive functions such as memory, orientation, judgement, and visual-spatial skills are relatively spared and mostly not affected until 5 to 7 years after disease onset. Structural imaging displays atrophy of the left temporal region which can also affect the frontal region or both hemispheres. Reduced neuronal activity in the left temporal lobe can be seen using functional imaging even before structural anomalies are detected. Neuropathological examination reveals neuronal cell loss and gliosis in the regions of atrophy which are sometimes accompanied by spongiform changes. T-positive neurons or plaques and neurofibrillary tangles are present in rare cases. A specific therapy is not known. Logopaedic therapy focussed on the main symptoms seems to stabilise linguistic abilities. PMID: 15257436 [PubMed - as supplied by publisher] HOMEPAGE TORNA INDIETRO

46. [DYSPHAGIA] Primary Progressive Aphasia Subject DYSPHAGIA primary progressive aphasia; From ingrid.scholten@flinders.edu.au (Ingrid Scholten); Date Fri, 18 Jun 1999 132744 +0900 http://list.dysphagia.com/dysphagia/1999-June/msg00129.html

Date Prev Date Next [Chronological] [Thread] ... [Top] [DYSPHAGIA] Primary Progressive Aphasia Subject [DYSPHAGIA] Primary Progressive Aphasia From ingrid.scholten@flinders.edu.au (Ingrid Scholten) Date: Fri, 18 Jun 1999 13:27:44 +0900 907b1e05.2497166e@aol.com http://www.flinders.edu.au/SpPathAudiol - To UNSUBSCRIBE from this list, please send an e-mail message to majordomo@cyberport.com with the following text as a message: unsubscribe dysphagia - References [DYSPHAGIA] Primary Progressive Aphasia From: KLASLP@aol.com (KLASLP@aol.com) Prev by Date: [DYSPHAGIA] aspiration Next by Date: [DYSPHAGIA] Aspiration pneumonia-diagnosis Index(es): Chronological Thread

47. [DYSPHAGIA] Primary Progressive Aphasia Subject DYSPHAGIA primary progressive aphasia; FromKLASLP@aol.com (KLASLP@aol.com); Date Mon, 14 Jun 1999 223734 EDT http://list.dysphagia.com/dysphagia/1999-June/msg00086.html

Date Prev Date Next [Chronological] [Thread] ... [Top] [DYSPHAGIA] Primary Progressive Aphasia Subject [DYSPHAGIA] Primary Progressive Aphasia From KLASLP@aol.com KLASLP@aol.com Date: Mon, 14 Jun 1999 22:37:34 EDT Please pardon the language question but I am seeking info on Primary Progressive Aphasia. A 63 year old friend was just given this dx. Although I've been an SLP for many years, I am not too familiar with the exact nature, treatment or prognosis of this disease. Any info would be greatly appreciated. Thanks- Karen Allen Howard County General Hospital Columbia, MD - To UNSUBSCRIBE from this list, please send an e-mail message to majordomo@cyberport.com with the following text as a message: unsubscribe dysphagia - Follow-Ups [DYSPHAGIA] Primary Progressive Aphasia From: ingrid.scholten@flinders.edu.au (Ingrid Scholten) Prev by Date: [DYSPHAGIA] oro-esophageal tubes Next by Date: [DYSPHAGIA] Dysphagia after laryngectomy Index(es): Chronological Thread

48. Speech&Hearing Characteristics and management of primary progressive aphasia. Dissolution ofspoken language in primary progressive aphasia. Aphasiology, 12(7/8), http://depts.washington.edu/sphsc/rogers.htm

Margaret A. Rogers, Ph.D. Associate Professor Neurogenic Speech-Language Disorders (For Campus Mail only: Box 354875) University of Washington 1417 NE 42nd St. Seattle, WA 98105-6246 mrogers@u.washington.edu Office:(206) 543-0094 Fax:(206) 543-1093 Speech-Language Pathology Division Dr. Margaret A. Rogers is currently an Associate Professor in the Department of Speech and Hearing Sciences at the University of Washington. She obtained her Ph.D. at the University of Iowa in 1992. Her research focuses on the study of spoken language production, particularly on how language is transformed into speech. The research conducted in Dr. Rogers' laboratory investigates this fundamental question from three distinct, yet inter-related, approaches. The first approach examines the process of producing single words by studying how similar sound structure (i.e., Phonologic Similarity ) among words affects the time it takes speakers to read target words aloud (i.e.

49. MEDICAL BIOLOGY: ON PARKINSON'S DISEASE DEMENTIA In contrast, patients with primary progressive aphasia come to medical attention primary progressive aphasia is diagnosed when other mental faculties, http://scienceweek.com/2005/sc050107-6.htm

Subscriptions Archives Contact Us Home ... Advertising ScienceWeek Crossing Barriers Since 1997 Receive free new report announcements by Email: ScienceWeek TOC Alerts About ScienceWeek Archives Contact Us ... Subscriptions ScienceWeek MEDICAL BIOLOGY: ON PARKINSON'S DISEASE DEMENTIA Notes by ScienceWeek: The term "Lewy bodies" refers to intracytoplasmic neuronal inclusions ("Lewy inclusion bodies"), especially noted in brainstem neurons and seen in Parkinson's disease. They are named after the neurologist Frederic H. Lewy (1885-1950). The following points are made by Daniel Z. Press (New Engl. J. Med. 2004 351:2547): 1) The hallmark of Parkinson's disease is involvement of the motor system, causing tremor, rigidity, and slowness of movement. But cognitive symptoms are frequently present at the time of diagnosis,[1] contribute heavily to disability,[2] and progress to dementia at an alarming rate. Dementia will develop in 40 to 70 percent of patients with Parkinson's disease during the course of their illness.[3] 2) The term "Parkinson's disease dementia" refers to dementia that develops at least two years after the diagnosis of Parkinson's disease. If dementia develops before or within two years after the onset of motor symptoms, then the criteria are met for the related condition, diffuse Lewy-body disease. Risk factors for Parkinson's disease dementia include advanced age, treatment-induced visual hallucinations, and more severe motor symptoms.[4] The cognitive profile is similar to that of Alzheimer's disease, but patients with Parkinson's disease dementia generally have more severe visuospatial deficits, large fluctuations in attention, frequent visual hallucinations, and less severe memory problems.[5]

50. University Of Miami School Of Medicine - Glossary - Aphasia, Primary Progressive Aphasia, primary progressive See primary progressive aphasia. Glossary contentCopyright © 19962002 MedicineNet, Inc. All rights reserved. http://www.med.miami.edu/glossary/art.asp?articlekey=39136

51. Unusual Form Of Memory Loss Often Confused For Alzheimer's Disease Mesulam described, for example, primary progressive aphasia, an unusual dementia of Once considered a rare condition, primary progressive aphasia is now http://www.medicalnewstoday.com/medicalnews.php?newsid=4499

52. Aphasia, Primary Progressive Aphasia, Primary Progressive Medical.WebEnds.com. Aphasia, Primary Progressive.Mesulam Syndrome; Progressive Nonfluent Aphasia; Mesulam s Syndrome; http://medical.webends.com/kw/Aphasia, Primary Progressive

Medical.WebEnds.com - Medical Terminology Dictionary A B C D ... Z WWW Medical.WebEnds.com Aphasia, Primary Progressive A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE , emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE . (From Brain 1998 Jan;121(Pt 1):115-26) Google links Processing time was 0.062615871429443 seconds.

53. EMedicine - Frontal And Temporal Lobe Dementia : Article By Howard Kirshner, MD This disorder, which is currently termed primary progressive aphasia (PPA), Mesulam MM primary progressive aphasiaa languagebased dementia. http://www.emedicine.com/NEURO/topic140.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Behavioral Neurology And Dementia Frontal and Temporal Lobe Dementia Last Updated: March 29, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: frontotemporal dementia, frontal dementia, nonspecific dementia, Pick's disease, Pick disease, primary progressive aphasia, FTD, PPA, motor neuron disease, Alzheimer disease, Alzheimer's disease, AD, semantic dementia, fluent aphasia, nonfluent aphasia AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Howard Kirshner, MD , Vice-Chair, Professor, Department of Neurology, Vanderbilt University School of Medicine Howard Kirshner, MD, is a member of the following medical societies: Alpha Omega Alpha American Academy of Neurology American Heart Association American Medical Association ... Phi Beta Kappa , and Tennessee Medical Association Editor(s): Robert A Hauser, MD

54. EMedicine - Pick Disease : Article Excerpt By: Anna M Barrett, MD primary progressive aphasia (Weintraub, 1990) is a focal atrophy syndrome thatmay be associated with Pick, Alzheimer, or other pathology; clinically the http://www.emedicine.com/neuro/byname/pick-disease.htm

(advertisement) Excerpt from Pick Disease Synonyms, Key Words, and Related Terms: dementia lacking distinctive histopathology, frontal lobe degeneration, frontal lobe dementia, frontotemporal dementia, frontotemporal dementia linked to chromosome 17, primary progressive aphasia, progressive subcortical gliosis Please click here to view the full topic text: Pick Disease Background: Pick disease (named after Arnold Pick) is a progressive dementia defined by clinical and pathologic criteria. Unlike Alzheimer disease and other dementias that present with cognitive deficits localized to the posterior (parietal) cortex, Pick disease typically affects the frontal and/or temporal lobes. First described in 1892, with the defining pathologic characteristics first reported by Alois Alzheimer in 1911, Pick disease now is considered by some to be part of a "complex" of neurodegenerative disorders with similar or related histopathologic and clinical features (Kertesz, 1994; Kertesz, 2003). Nomenclature history Frontotemporal dementia (of which Pick disease is an example) is a broader term including Pick disease. Frontal lobe dementia is a term signifying neuropsychological features localizing to the frontal lobes. Clinically, Pick disease may be identical or very similar to "frontal lobe degeneration" (Miller, 1997).

55. Penn State Faculty Research Expertise Database (FRED) Nonfluent Aphasia, Progressive, Nonfluent Aphasias, Progressive. Primary ProgressiveAphasia, primary progressive aphasias. Progressive Aphasia, Primary http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D018888

56. Health/Conditions And Diseases/Neurological Disorders/Dementia/Primary Progressi Understanding primary progressive aphasia An article with a description, assistanceavailable and where to obtain additional information. http://www.thedoctorslounge.net/dir/Health/Conditions_and_Diseases/Neurological_

Advertisement Powered by Careerbuilder Search for: Home Humor Advertising Contact ... Links Specialties Cardiology Chest diseases Dermatology Endocrinology ... Urology Other Sections Membership Research Tools Medical Tutorials Medical Software ... Specialized Centers Headlines: The Medical Website Directory Popular Categories Popular Links Web Sites Understanding Primary Progressive Aphasia An article with a description, assistance available and where to obtain additional information. url: www.aphasia.org/NAAppa.html WebMD Live Chat Transcript: Living with aphasia with Martha Taylor Sarno, MD. url: my.webmd.com/content/asset/chat_transcript.526505 mozilla.org url: mozilla.org/ More Search All the Web AltaVista Gigablast Google USENET ... Yahoo In association with ODP Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor Are you a physician or a nurse? Would you like to join us and help patients online by volunteering even a few minutes of your time? Get started here by becoming a member of The Doctors Lounge We subscribe to the HONcode principles.

57. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor More books about primary progressive aphasia . Understanding Primary ProgressiveAphasia An article with a description, assistance available and where to http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Dementia : Primary Progressive Aphasia Subtopics Search Google: Primary Progressive Aphasia News Books Links ... Animal Model Of Parkinson's Disease Reveals Striking Sensitivity To Common Environmental Toxins (September 9, 2005) full story Can Ancient Rocks Yield Clues About Catastrophes Like Hurricane Katrina? (September 8, 2005) full story Breast Cancer Gene Increases Risk Of Several Cancers In Men (September 6, 2005) Journal of Medical Genetics . The mutation in the BRAC2 gene may also increase the risk of bone and throat cancers, the data suggest. full story Physical Fitness Cuts Men's Heart Disease Risk In Half, New Queen's Study Shows (September 4, 2005) full story Cancer Drug Target Chk1 May Also Be Source Of Drug Resistance (September 4, 2005) Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs. The study is expected to help academic researchers and biotechnology and pharmaceutical companies design drugs that combat cancer using this checkpoint protein, but with fewer side effects. full story K-State Researchers Designing Better Drug To Treat Cystic Fibrosis (September 4, 2005)

58. Unusual Form Of Memory Loss Often Confused With Alzheimer's Disease Mesulam described, for example, primary progressive aphasia, an unusual dementia In contrast, patients with primary progressive aphasia come to medical http://www.sciencedaily.com/releases/2003/10/031017073151.htm

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Advertise With Us Source Northwestern University Date Print this page Email to friend Unusual Form Of Memory Loss Often Confused With Alzheimer's Disease Alzheimer's disease is the single most common cause of dementia, a chronically progressive brain condition that impairs intellect and behavior to the point where customary activities of daily living become compromised. Over 4 million Americans have Alzheimer's disease. Its high prevalence may lead people to believe that dementia is always due to Alzheimer's disease and that memory loss is a feature of all dementias. Related News Stories (July 28, 1999) A Mayo Clinic study has shown that 50 percent of a group of elderly patients with mild cognitive impairment who also have a significantly smaller hippocampus portion of the brain are likely to ... full story (January 2, 1998) full story USC Scientists Identify Enzyme Important In Short-Term Memory (November 13, 1998) full story (March 20, 2001)

59. Karger Publishers primary progressive aphasia with Glial Cytoplasmic Inclusions Primary progressiveaphasia; Neuropathology; Glial cytoplasmic inclusions; Multiple system http://content.karger.com/ProdukteDB/produkte.asp?Doi=7961

60. Unusual Form Of Memory Loss Often Confused For Alzheimer's Disease Once considered a rare condition, primary progressive aphasia is now commonly In contrast, patients with primary progressive aphasia come to medical http://www.scienceblog.com/community/older/2003/G/20034674.html

October 2003 From Northwestern University Unusual form of memory loss often confused for Alzheimer's disease Alzheimer's disease is the single most common cause of dementia, a chronically progressive brain condition that impairs intellect and behavior to the point where customary activities of daily living become compromised. Over 4 million Americans have Alzheimer's disease. Its high prevalence may lead people to believe that dementia is always due to Alzheimer's disease and that memory loss is a feature of all dementias. However, an article by Alzheimer's disease expert M.-Marsel Mesulam, M.D., in the Oct. 16 issue of The New England Journal of Medicine reports that nearly a quarter of all dementias, especially those of presenile onset, may be caused by diseases other than Alzheimer's disease and that some of these so-called atypical dementias involve cognitive abnormalities in areas other than memory. Mesulam is Ruth and Evelyn Dunbar Professor of Psychiatry and Behavioral Sciences and professor of neurology at the Feinberg School of Medicine and director of the Cognitive Neurology and Alzheimer's Disease Center at Northwestern University. Mesulam described, for example, primary progressive aphasia, an unusual dementia of unknown cause that is characterized by a relentless loss of language but with memory relatively preserved. Once considered a rare condition, primary progressive aphasia is now commonly included among dementia syndromes and has been reported in several hundred individuals.

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