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         Primary Ovarian Failure:     more detail

1. EMedicine - Ovarian Failure : Article Excerpt By: Vladimir Bakalov, MD
Ovarian Failure The human ovary functions as both a reproductive organ and an reproductive organs, premature ovarian failure, primary ovarian failure,
http://www.emedicine.com/med/byname/ovarian-failure.htm
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Excerpt from Ovarian Failure
Synonyms, Key Words, and Related Terms: ovaries, reproductive organs, premature ovarian failure, primary ovarian failure, premature menopause, primary ovarian insufficiency, POF, anovulation, endocrine failure
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Background: The human ovary functions as both a reproductive organ and an endocrine organ. These functions are tightly coupled. Predictable cyclicity is the hallmark of healthy ovarian function during the reproductive years. Each month, highly coordinated hormonal and ovarian morphological changes develop and release a mature oocyte that is ready for fertilization. A disruption of this process results in reproductive failure (anovulation) or endocrine failure (low serum levels of ovarian steroid hormones and inhibins). Ovarian failure due to inappropriate regulatory signals (hypothalamic or pituitary pathology) is known as secondary ovarian failure. Ovarian failure due to a pathological process directly affecting the ovaries (eg, chemotherapy, irradiation, autoimmunity, chromosomal abnormalities) is known as primary ovarian failure (POF). A simple means of distinguishing between the 2 conditions is to measure serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels (elevated in POF and low or normal in secondary ovarian failure). Aging is associated with a decline in the number of ovarian follicles, menstrual irregularities, ovarian hormonal deficiency, anovulation, decreased fertility, and, finally, a complete and irreversible cessation of menses known as menopause, usually occurring at a mean age of 51 years.

2. The International Premature Ovarian Failure Association
Information and support for women with premature ovarian failure (POF, also called premature or early menopause), an endocrine disorder affecting
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3. Primary Ovarian Failure
primary ovarian failure From D. Category General Infertility SUBMIT Post Article Date 11/2/2002 Time 40824 PM Remote Name 64.157
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4. The Early Dehydroepiandrosterone Sulfate Rise Of Adrenarche And
The Early Dehydroepiandrosterone Sulfate Rise of Adrenarche and the Delay of Pubarche Indicate primary ovarian failure in Turner Syndrome
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5. Primary Ovarian Failure
primary ovarian failure drug treatment. Drugs related to primary ovarian failure. Alora (consumer information) Cenestin (consumer information)
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Alora (consumer information)
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conjugated estrogen and medroxyprogesterone combinations
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conjugated estrogens
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conjugated estrogens y medroxyprogesterone
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Delestrogen
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Depo-Estradiol
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Esclim
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esterified estrogens
(consumer information) Estrace (consumer information) Estraderm (consumer information) estradiol (consumer information) estradiol topical patches (consumer information) Estratab (consumer information) Estrogel 0.06% (professional information) estropipate (consumer information) Fempatch (consumer information) Femring (consumer information) Gynodiol (consumer information) Menest (consumer information) Ogen (consumer information) Ogen 0.625

6. A Novel Mutation In The FSH Receptor Inhibiting Signal
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7. Clinical Features Of Primary Ovarian Failure Caused By A Point Mutation In The F
Clinical features of primary ovarian failure caused by a point mutation in the Pregnancies after oocyte donation in women with ovarian failure caused by
http://jcem.endojournals.org/cgi/content/abstract/81/10/3722

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Clinical features of primary ovarian failure caused by a point mutation in the follicle-stimulating hormone receptor gene
K Aittomaki, R Herva, UH Stenman, K Juntunen, P Ylostalo, O Hovatta and A de la Chapelle
Department of Medical Genetics, University of Helsinki, Finland. kristiina.aittomaki@helsinki.fi The recent finding that a mutation in the FSH receptor gene causes ovarian dysgenesis prompted the present study to determine the phenotype caused by this mutation. Twenty-two patients with ovarian dysgenesis and a ovaries or FSHRO) were compared with 30 clinically similar patients with ovarian dysgenesis (designated ODG) who did not have this mutation. The

8. A Novel Mutation In The FSH Receptor Inhibiting Signal
A Novel Mutation in the FSH Receptor Inhibiting Signal Transduction and Causing primary ovarian failure Elaine Doherty , Pirjo Pakarinen
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9. Clinical Features Of Primary Ovarian Failure Caused By A Point Mutation In The F

http://jcem.endojournals.org/cgi/reprint/81/10/3722
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10. JAMA Lipid Profiles In Women With 45 X Vs 46 XX Primary Ovarian
Lipids and Lipid Disorders. . Collection Email Alerts Lipid Profiles in Women With 45 X vs 46 XX primary ovarian failure
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11. Primary Ovarian Failure Caused By A Solvent Containing 2-bromopropane -- Koh Et
primary ovarian failure caused by a solvent containing 2bromopropane. JM Koh, CH Kim, SK Hong, KU Lee, YT Kim, OJ Kim, and GS Kim
http://www.eje-online.org/cgi/content/abstract/138/5/554
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DOI: 10.1530/eje.0.1380554
This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager PubMed PubMed Citation Articles by Koh, J. Articles by Kim, G. European Journal of Endocrinology, Vol 138, Issue 5, 554-556
Case Reports
Primary ovarian failure caused by a solvent containing 2-bromopropane
JM Koh, CH Kim, SK Hong, KU Lee, YT Kim, OJ Kim, and GS Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Sixteen Korean female laborers who had been exposed to a cleaning solvent composed mainly of 2-bromopropane developed primary ovarian failure. Histologic findings from these patients' ovaries were similar to those observed in ovarian failure caused by radiation or chemotherapy, i.e., reduced number and developmental arrest of primary follicles, interstitial fibrosis and hyalinization of blood vessels. We followed their clinical course for 2 years and found that two patients recovered normal ovarian function spontaneously: one became pregnant and delivered a normal full-term baby, and the other resumed regular menstrual periods with normal hormonal values. Our observations support the idea that the increasing prevalence of ovarian failure in recent years might be due to an increase in presently unidentified environmental toxic agents.

12. 856 Primary Ovarian Failure Associated To A
Program Nr 856 primary ovarian failure associated to a 46 XX t(6;18)(p23;q22) balanced reciprocal translocation.
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13. Primary Ovarian Failure Caused By A Solvent Containing 2-bromopropane -- Koh Et

http://www.eje-online.org/cgi/reprint/138/5/554
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14. Primary Ovarian Failure
Women who have a defective LH receptor present with primary amenorrhoea with the typical picture of primary ovarian failure.
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15. Increased Prolactin Response To Thyrotropin-releasing Hormone In Primary Ovarian
secretion in ovarian failure, 14 women with primary ovarian failure were PRL responses to TRH noted in these patients with primary ovarian failure.
http://www.greenjournal.org/cgi/content/abstract/59/3/280
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Increased prolactin response to thyrotropin-releasing hormone in primary ovarian failure
D Hochner-Celnikier, E Zylber-Haran, S Shilo, Z Palti, and IM Spitz
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16. Webkatalog
5. Premature Ovarian Failure Information and support for women with premature ovarian failure (POF, also called premature or early
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17. Spontaneous And Pharmacologically Induced Remissions In Patients With Premature
None of the 23 patients with primary ovarian failure ovulated. Seven of 63 (11.1%) with secondary ovarian failure did ovulate, and three of 63 (4.8%)
http://www.greenjournal.org/cgi/content/abstract/72/6/926
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This Article Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by Kreiner, D Articles by Rosenwaks, Z
Articles
Spontaneous and pharmacologically induced remissions in patients with premature ovarian failure
D Kreiner, K Droesch, D Navot, R Scott, and Z Rosenwaks
This article has been cited by other articles:
D. Goswami and G. S. Conway
Premature ovarian failure
Hum. Reprod. Update, July 1, 2005; 11(4): 391 - 410.
[Abstract]
[Full Text] [PDF]
M. R. Laufer
Reproductive Issues for Cancer Patients/Survivors J. Clin. Oncol., September 1, 1999; 17(9): 2631 - 2631. [Full Text] [PDF] HOME HELP ... TABLE OF CONTENTS

18. Arch Pediatr Adolesc Med Abstract Primary Ovarian Failure
primary ovarian failure, juvenile rheumatoid arthritis, and vitiligo. R. J. Collen, B. M. Lippe and S. A. Kaplan
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19. LH: The Test
Increased levels of LH and FSH are seen in primary ovarian failure. Some causes of primary ovarian failure are listed below. Developmental defects
http://www.labtestsonline.org/understanding/analytes/lh/test.html
TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

20. LH: The Test
Increased levels of FSH and LH are consistent with primary ovarian failure. Some causes of primary ovarian failure are listed below. Developmental defects
http://www.labtestsonline.org.uk/understanding/analytes/lh/test.html
TESTS test not listed? ACTH AFP Tumour Marker Albumin Aldosterone Allergy Blood Test (IgE) ALP Alpha-1 Antitrypsin ALT Amylase ANA Apo A ApoE Genotyping AST B12 / Folate Bicarbonate Bilirubin Blood Culture Blood Gases BNP Bone Markers BRCA C-peptide CA-125 CA 15-3 CA 19-9 Calc. Cr Cl Calcium Cardiac Risk CEA Cervical screening Cervical Smear CF Gene Mutation Chlamydia Chloride Cholesterol Cortisol Creatine kinase (CK) CK-MB Creatinine Creatinine Clearance CRP CRP, high-sensitivity Cystatin C Differential Electrolytes ESR Faecal Occult Blood FBC Ferritin Fibrinogen Flu Tests FSH GFR GGT Glucose Gonorrhoea Gram Stain Hormone Receptors Haemoglobin HbA1c / GHb hCG HDL Hepatitis A Hepatitis B Hepatitis C Her-2/neu Herpes HIV Antibody HIV Resistance Home Tests Homocysteine HPV H. pylori hs-CRP Immunoelectrophoresis INR Insulin Iron Iron studies (Fe) IRT LD LDH LDL Lead LH Lipase Lipid Profile Liver Function Tests Lupus Anticoagulant Lyme Disease Magnesium Maternal Screening Microalbumin Monospot Myoglobin Oestrogen Osmolality PCV Phosphate Platelets Potassium Prealbumin Pregnancy test Preoperative Tests Progesterone Prolactin Protein C Protein S Protein Elec.

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