81. UpToDate Treatment Of Adult Dermatomyositis And Polymyositis Treatment of adult dermatomyositis and polymyositis. Marc L Miller, MD. UpToDate performs a continuous review of over 330 journals and other resources. http://patients.uptodate.com/topic.asp?file=muscle/5342

82. UpToDate Treatment Of Juvenile Dermatomyositis And Polymyositis INTRODUCTION — Juvenile dermatomyositis (JDM) and polymyositis (JPM) are relatively rare inflammatory myopathies of childhood manifested predominantly by http://patients.uptodate.com/topic.asp?file=pedirheu/5841

83. Immunosuppressant And Immunomodulatory Treatment For Dermatomyositis And Polymyo treatment for dermatomyositis and polymyositis (Cochrane Review) with probable or definite dermatomyositis and polymyositis as defined by the http://www.update-software.com/Abstracts/AB003643.htm

From The Cochrane Library, Issue 3, 2005 Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis (Cochrane Review) Choy EHS, Hoogendijk JE, Lecky B, Winer JB ABSTRACT What's new in this issue Search abstracts Browse alphabetical list of titles Browse by Review Group A substantive amendment to this systematic review was last made on 10 March 2005. Cochrane reviews are regularly checked and updated if necessary. Background: Idiopathic inflammatory myopathies are chronic skeletal diseases with significant mortality and morbidity despite treatment by corticosteroids. Immunosuppressive agents and immunomodulatory therapy are used to improve disease control and reduce the long-term side effects of corticosteroids. While these treatments are used commonly in routine clinical practice, the optimal therapeutic regimen remains unclear. Objectives: To systematically review the evidence for the effectiveness of immunosuppressants and immunomodulatory treatments for dermatomyositis and polymyositis. Search strategy: We searched the Cochrane Neuromuscular Disease Group trials register (searched February 2002 and updated in November 2003) and MEDLINE (January 1966 to December 2002). We checked bibliographies of identified trials and wrote to disease experts.

84. Polymyositis/scleroderma Autoantigen 1 You are at Home » Proteins » polymyositis/scleroderma autoantigen 1 Suggest a Protein Molecule Authority. polymyositis/scleroderma autoantigen 1 http://www.hprd.org/protein/07315

You are at: Home Proteins Polymyositis/scleroderma autoantigen 1 Polymyositis/scleroderma autoantigen 1 Ribonuclease Ribonuclease activity Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism ALTERNATE NAMES DISEASES ... EXTERNAL LINKS Gene Symbol : Molecular Weight (Da) : Gene Map Locus Localization Primary Nucleolus Alternative Domains and Motifs Domains Motifs EXPRESSION Site of Expression Placenta Please send any questions or comments about the Human Protein Reference Database to help This is a joint project between: and

85. Polymyositis And Dermatomyositis polymyositis and dermatomyositis are connective tissue diseases in which there is muscle What is the cause of the polymyositis and dermatomyositis? http://ww3.komotv.com/global/story.asp?s=1230494

86. Dermatomyositis And Polymyositis Dermatomyositis and polymyositis are connective tissue diseases in which there is The major manifestation of polymyositis is inflammation leading to http://ww3.komotv.com/global/story.asp?s=1230496

87. About - Myositis. Myositis refers to several different illnesses, including polymyositis, dermatomyositis, and inclusion body myositis. http://www.orthop.washington.edu/uw/myositis/tabID__3376/ItemID__41/Articles/Def

Home Site Map Contact Us Links ... All Articles Myositis. University of Washington, Seattle Last updated Friday, February 11, 2005 About Basics of myositis Myositis is the term for illnesses that involve chronic muscle inflammation ("myo" means muscle and "itis" means inflammation). "Myositis" refers to several different illnesses, including polymyositis, dermatomyositis, and inclusion body myositis. All forms of myositis involve chronic, or persistent, muscle inflammation. This muscle inflammation almost always results in weakness, and less often in heat, swelling, and pain of the muscles. Myositis can affect many parts of the body. Sometimes the joints, heart, lungs, intestines, and skin can become inflamed. Some forms of myositis, like dermatomyositis ("dermato" refers to the skin), result in particular rashes over the knuckles, around the eyes, or sometimes in other parts of the body. Other forms of myositis occur in children. Some forms are seen with other connective tissues diseases, like lupus or rheumatoid arthritis . Still other forms may occur in people with tumors. Rarely, myositis can occur in a single part of the body, such as one arm, one leg, or just the muscles that move the eye.

88. InteliHealth: Polymyositis InteliHealth Featuring Harvard Medical School s consumer health information. Information on symptoms and treatment for mental health, diabetes, asthma, http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10194.html

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89. InteliHealth: Polymyositis/dermatomyositis InteliHealth Featuring Harvard Medical School s consumer health information. For more than 550 diseases and conditions, learn What Is It?, Symptoms, http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10388.html

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90. Ivpcare > Areas Of Specialty > Arthritis > Information Center > Article Library However, dermatomyositis and polymyositis are of unknown cause and are thought to be Both dermatomyositis and polymyositis cause weakness of muscles, http://www.ivpcare.com/areas_of_specialty/arthritis/information_center/articles/

Arthritis Information Center Article Library Manufacturer Info Books ... Articles : Psoriatic Arthritis By: Robert H. Shmerling, M.D. Blood tests usually demonstrate evidence of muscle inflammation. The creatine phosphokinase (CPK) and aldolase, enzymes that are found in muscle tissue, tends to be markedly elevated. Other helpful tests include electromyogram (EMG) and muscle biopsy. The EMG is an electrical recording from muscle tissue and the biopsy is a minor surgical procedure in which a small piece of muscle is removed and examined under the microscope. Physicians integrate all of this information together, including the symptoms, physical examination, blood tests, EMG results and muscle biopsy to arrive at a diagnosis of dermatomyositis or polymyositis. In some cases, it can take weeks or even months to make the diagnosis. Once the diagnosis is established, the treatment of these types of myositis usually include corticosteroids (such as prednisone) in high doses for at least a month or two followed by a dose reduction over a number of weeks or months. If the weakness does not respond to steroids of if weakness and muscle inflammation recur when the steroids are reduced, a number of other drugs may be effective, particularly methotrexate, azathioprine or intravenous immunoglobulin (IVIG). It is important that people with inflammatory muscle disease remain as active as possible and to take measures to prevent the osteoporosis that may complicate corticosteroid use. Calcium and vitamin D supplementation and prescription medications (such as alendronate or risedronate) may prevent bone loss and reduce the risk of fractures.

91. POLYMYOSITIS In late april of 1997 I was diagnosed with polymyositis. I was diagnosed and tested positive with polymyositis/antiSRP (signal recognition particle) http://www.rheumatic.org/steve.htm

STEVE, polymyositis In late april of 1997 I was diagnosed with polymyositis. My CPK level was 7,956. It all started in mid to late january 97 with a pain in the calf of my right leg; then aches and pains with burning muscles that got progressively worse with each passing week. Swallowing became very difficult. It was like I had the worst case of the flu ever, multiplied by a thousand. Finally I went to my GP doctor. I was tested for hepatitis, liver disease, weeks of those tests with nothing confirmed. Then I saw his associate in his absence and she wanted me to have a special test (CPK). Meanwhile a friend of mine had a bad bacterial infection that was going around and she had taken Zithromax (azithromycin) to get rid of it. I thought that was probably what I had and was sure it would help me, because my symptons were the same, only more severe. So I made a deal with the doctor - I'd go immediately for the CPK test if she would give me a prescription for Zithromax. She agreed to do that, then stated it wouldn't help. That's when I had a CPK count of 7,956. But the Zithromax did help me quite a bit. The next day I was able to lift my arms, etc.

92. Definition Of Polymyositis - WordReference.com Dictionary polymyositis Definition from dictionary. 1, polymyositis. myositis characterixed by weakness of limb and neck muscles and much muscle pain and swelling; http://www.wordreference.com/definition/polymyositis

Word Reference .com polymyositis A noun polymyositis myositis characterixed by weakness of limb and neck muscles and much muscle pain and swelling; progression and severity vary among individuals Category Tree: cognition knowledge noesis information ... myositis polymyositis Need more information? Ask a question in the forum. Look up "polymyositis" at Merriam-Webster Look up "polymyositis" at dictionary.com English Definition Home Suggestions Search Tips See Also: polymerization polymerize Polymonium_caeruleum_van-bruntiae polymorph ... Polyodon polymyositis: in French in Italian in Spanish

93. Clinical Trial: Rituximab For The Treatment Of Dermatomyositis And Polymyositis Diagnosis of dermatomyositis or polymyositis by Bohan and Peter criteria OR Diagnosis Juvenile polymyositis; Inclusion body myositis; Cancerassociated http://www.clinicaltrials.gov/ct/show/NCT00106184

Home Search Browse Resources ... About Rituximab for the Treatment of Dermatomyositis and Polymyositis This study is not yet open for patient recruitment. Verified by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) April 2005 Sponsored by: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Information provided by: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ClinicalTrials.gov Identifier: Purpose Rituximab is a man-made antibody used to treat certain types of cancer. This study will determine whether rituximab is an effective treatment for adult and pediatric patients with dermatomyositis or polymyositis. Study hypotheses: 1) The time to improvement in Group A patients (receiving rituximab first) will occur significantly earlier than Group B patients (receiving rituximab later). 2) The proportion of patients improved at week 9 of the treatment phase will be significantly greater in Group A compared with Group B. Condition Intervention Phase Myositis Dermatomyositis Polymyositis Drug: Rituximab Phase II MedlinePlus related topics: Myositis Study Type: Interventional Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study

94. Polymyositis polymyositis is a systemic connective tissue disorder characterized by inflammatory and degenerative changes in the muscles, leading to symmetric weakness http://www.bchealthguide.org/kbase/nord/nord278.htm

var hwPrint=1;var hwDocHWID="nord278";var hwDocTitle="Polymyositis";var hwRank="1";var hwSectionHWID="nord278-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Polymyositis Important It is possible that the main title of the report Polymyositis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms None Disorder Subdivisions Primary Idiopathic Polymyositis Childhood Polymyositis Polymyositis Associated with Malignant Tumors Polymyositis Associated with Sclerodermatomyositis Polymyositis Associated with Mixed Connective Tissue Disease (Overlap Syn) General Discussion Polymyositis is a systemic connective tissue disorder characterized by inflammatory and degenerative changes in the muscles, leading to symmetric weakness and some degree of muscle atrophy. The areas principally affected are the hip, shoulders, arms, pharynx and neck. Resources Arthritis Foundation 1330 West Peachtree Street Atlanta, GA 30309

95. Polymyositis Information The Glaxo Neurological Centre, Non medical advice and information for people with neurological conditions and their carers. http://glaxocentre.merseyside.org/polymyositis.html

Polymyositis Information For information about Polymyositis please see the following websites: Muscular Dystrophy Association of Australia: information about POLYMYOSITIS/DERMATOMYOSITIS The Muscular Dystrophy Campaign in the UK: information on Polymyositis, dermatomyositis and sarcoid myopathy National Institute of Neurological Disorders and Stroke: Polymyositis fact sheet The Muscular Dystrophy Association in the US: Facts About Polymyositis and Dermatomyositis (PM/DM) UK Arthritis Research Campaingn Information booklet for Polymyositis and dermatomyositis There is a Myositis Support Group in the UK Visit their website More links will be added soon. Please contact the Information Officer if you are looking for more information about Polymyositis or any neurological condition (contact details below). The Glaxo Neurological Centre is a unique non-medical advice and information centre for people with neurological conditions and their carers For more information about neurological conditions contact the Information Officer by e-mailing mnt@gnc.u-net.com

96. Dr. Koop - Polymyositis And Dermatomyositis- Health Encyclopedia And Reference polymyositis and Dermatomyositis Symptoms, Treatments and Medications. http://www.drkoop.com/encyclopedia/93/29/Polymyositis_and_Dermatomyositis.html

Home Diseases Rheumatoid Arthritis Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Health Encyclopedia - Diseases and Conditions A B C D ... Y Polymyositis and Dermatomyositis What is the Definition of Polymyositis and Dermatomyositis? Description of Polymyositis and Dermatomyositis Causes of Polymyositis and Dermatomyositis Symptoms of Polymyositis and Dermatomyositis ... What Questions to ask Your Doctor About Polymyositis and Dermatomyositis? What is the Definition of Polymyositis and Dermatomyositis? Polymyositis and dermatomyositis are connective tissue diseases in which there is muscle weakness and tenderness. The two disorders are very similar, except dermatomyositis involves the skin as well as the muscles, while polymyositis involves only the muscles. top ^ Description of Polymyositis and Dermatomyositis The major manifestation of polymyositis is inflammation leading to destruction of muscle and increasing muscular weakness. As the disease progresses, the muscle tissue is replaced by functionless scar tissue. Both have features in common with rhematoid arthritis lupus , and progressive systemic sclerosis ( scleroderma top ^ Causes of Polymyositis and Dermatomyositis The causes of polymyositis and dermatomyositis are unknown. It appears that abnormal immunological factors are responsible for at least part of inflammatory attack against muscle tissue. The symptoms of muscular weakness usually wax and wane, but in some instances, the disease may progress rapidly.

97. Dr. Koop - Dermatomyositis And Polymyositis- Health Encyclopedia And Reference Dermatomyositis and polymyositis Symptoms, Treatments and Medications. http://www.drkoop.com/encyclopedia/93/31/Dermatomyositis_and_Polymyositis.html

Home Diseases Rheumatoid Arthritis Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Health Encyclopedia - Diseases and Conditions A B C D ... Y Dermatomyositis and Polymyositis What is the Definition of Dermatomyositis and Polymyositis? Description of Dermatomyositis and Polymyositis Causes of Dermatomyositis and Polymyositis Symptoms of Dermatomyositis and Polymyositis ... What Questions to ask Your Doctor About Dermatomyositis and Polymyositis? What is the Definition of Dermatomyositis and Polymyositis? Dermatomyositis and polymyositis are connective tissue diseases in which there is muscle weakness and tenderness. The two disorders are very similar, except that dermatomyositis involves the skin as well as the muscles, while polymyositis involves only the muscles. top ^ Description of Dermatomyositis and Polymyositis The major manifestation of polymyositis is inflammation leading to destruction of muscle and increasing muscular weakness. As the disease progresses, muscle tissue is replaced by functionless scar tissue. Both have features in common with rhematoid arthritis lupus , and progressive systemic sclerosis ( scleroderma top ^ Causes of Dermatomyositis and Polymyositis The causes of dermatomyositis and polymyositis are unknown. It appears that abnormal immunological factors are responsible for at least part of inflammatory attack against muscle tissue. The symptoms of muscular weakness usually wax and wane, but in some instances, the disease may progress rapidly.

98. Rheumatology -- Collected Resources : Dermatomyositis And Polymyositis Dermatomyositis and polymyositis. No articles have yet been added on this topic. Raynaud s Phenomenon Scleroderma Dermatomyositis and polymyositis http://rheumatology.oxfordjournals.org/cgi/collection/dermatomyositis_polymyosit

JOURNAL HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH RESULT QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Dermatomyositis and Polymyositis No articles have yet been added on this topic. Collected Resources Home Related collections: Paediatric Rheumatology Juvenile Idiopathic Arthritis Spondylarthropathies Lyme Disease ... Scleroderma Dermatomyositis and Polymyositis Vasculitis Kawasaki Disease Benign Hypermobile Joint Syndrome and Ehlers Dahnlos Syndrome Fibromyalgia and Chronic Fatigue ... SEARCH RESULT

99. Polymyositis: Häufigkeit, Symptome, Diagnose, Therapie, Weitere Informationen Translate this page Hier erfahren Sie alles über die polymyositis und andere Autoimmunerkrankungen Symptome, Diagnose, Therapie, aktuelle Nachrichten und weitere http://www.autoimmun.org/erkrankungen/polymyositis.html

Polymyositis idiopathische Polymyositis (30%) idiopathische Dermatomyositis (25%) Polymyositis/Dermatomyositis bei malignen Tumoren (10%) Polymyositis/Dermatomyositis als Begleiterkrankungen bei anderen Autoimmun-Erkrankungen wie dem systemischen Lupus Erythematodes Symptome muskelkaterartige Schmerzen bei etwa 60% der Betroffenen Diagnose Typisches Bild in der Muskelbiopsie mit einem Nebeneinander von Degeneration und Regeneration. Therapie Prognose: Weitere Informationen finden Sie unter (externe Links): Rheuma-online.de Hier erhalten Sie Informationen zur Mitgliedschaft. Bitte klicken Sie hier! Weitere Informationen zu Autoimmun-Erkrankungen: Ursachen von Autoimmun-Erkrankungen Behandlung Autoimmun-Erkrankungen von A-Z Bitte beachten Sie unseren Haftungshinweis [ Haftungshinweis im Impressum Weitere Autoimmun-Erkrankungen Alopecia areata (Kreisrunder Harrausfall) Antiphospholipid-Syndrom (APS, Hughes-Syndrom) Arteriitis temporalis (Riesenzellarteriitis) Atherosklerose (Arteriosklerose, Arterienverkalkung) ... Pemphigus vulgaris (Blasensucht) siehe auch: Polymyalgia rheumatica Polymyositis Polyneuropathie, chronisch-inflammatorisch demyelinisierende (siehe auch:

100. Essentials Of Clinical Immunology Chapter 10 Case Studies Case 10.14 polymyositis kinase was found to be very high and a muscle biopsy showed necrosis and a cellular infiltrate compatible with polymyositis. http://www.immunologyclinic.com/case.asp?chap=10&case=14

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