21. CFA Health Committee - PKD Seminar Update polycystic kidney Disease affects 600000 Americans and more than 12 million polycystic kidney disease. Consultations in Feline Internal Medicine 2. ed http://www.cfa.org/health/pkd-seminar.html

Feline Health Asthma Inflammatory Bowel Disease Cat Scratch Disease Feline Immunodeficiency Virus (FIV) ... Hip Dysplasia Autosomal Dominant Polycystic Kidney Disease in Persian Cats Polycystic Kidney Disease Seminar Feline Respiratory Virus Non-obstructive Lower Urinary Tract Disease in the Cat Feline Bladder Stones and Urinary Obstructions Feline Reproduction Feline Reproduction Series Blood Type Incompatibility and Kitten Mortality Feline Care Antifreeze Warning! Chronic Gingivitis in the Cat Early Spay/Neuter in the Cat Feline Dental Pathology and Care ... Vaccination Protocols for Catteries Cats and Plants Easter Lilies Deadly to Cats Lilies Dangerous to Cats Non-Toxic Plants Toxic Plants Related Links Pet Ownership for Immunocompromised People Feline Genome Project - Genetics! for Cats Polycystic Kidney Disease Seminar Update by Betty White Chairman, CFA Health Committee Philadelphia, PA June 1998 The PKD Seminar was held in Philadelphia at the CFA Annual on Saturday at 2 pm and lasted, with questions and answers, until 4 pm. The group attending numbered about 75, a very good turnout considering the variety of options available that afternoon. Pamphlets which were reproductions of the CFA Health Committee website article on PKD were available. Joining me on the panel were Debi Faryna (NIH and one of our genetics advisors to Breeds and Standards), Sue Helmke (Marhei Persians), Hilary Helmrich (President of the Winn Foundation/Abydos Abyssinians and Persians), Dr. Leslie Lyons (NIH and presently involved in the Havana Brown project), and Anna Sadler (CFA Legislative Committee/Brannaway Persians).

22. Polycystic Kidney Disease National Center for Biotechnology Information a division of the National Library of Medicine at the National Institutes of Health gives a description of this disease. http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.

23. Murine Models Of Polycystic Kidney Disease Molecular And Murine models of polycystic kidney disease molecular and therapeutic insights Lisa M. GuayWoodford http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

24. EMedicine - Polycystic Kidney Disease : Article By Roser Torra, MD, PhD polycystic kidney Disease Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited disorders in humans. http://www.emedicine.com/med/topic1862.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Nephrology Polycystic Kidney Disease Last Updated: November 18, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: PKD, autosomal dominant polycystic kidney disease, ADPKD, adult polycystic kidney disease, polycystic kidney disease type 1, PKD1, polycystic kidney disease type 2, PKD2, polycystic kidney disease type 3, PKD3, kidney failure, renal failure, dialysis-dependent kidney disease, renal cysts, kidney cysts, end-stage renal disease, ESRD, end-stage kidney disease, ESKD, renal transplantation, renal transplant, kidney transplantation, kidney transplant, hemodialysis, peritoneal dialysis AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Roser Torra, MD, PhD

25. The Feline PKD Home Page; Information About "Autosomal Dominant Information about Autosomal Dominant polycystic kidney Disease, Feline PKD, PKD in cats http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

26. EMedicine - Autosomal Dominant Polycystic Kidney Disease : Article By Ali Nawaz Autosomal Dominant polycystic kidney Disease Adult polycystic kidney disease is transmitted as an autosomal dominant trait and affects approximately 1 in http://www.emedicine.com/radio/topic68.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Radiology Genitourinary Autosomal Dominant Polycystic Kidney Disease Last Updated: August 12, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: Potter type III disease, adult polycystic kidney disease, kidney disease, polycystic kidney disease, renal cyst, ADPKD, ADPCKD, renal failure, hypertension, impaired renal function, AUTHOR INFORMATION Section 1 of 12 Author Information Introduction Differentials X-ray ... Bibliography Author: Ali Nawaz Khan, MBBS, FRCP, FRCR , Consultant Radiologist, Department of Diagnostic Radiology, North Manchester General Hospital Coauthor(s): Muthusamy Chandramohan, MBBS, DMRD, FRCR , Special Registrar, Department of Radiology, Manchester Radiology; Sumaira Macdonald, MBChB, MRCP, FRCR, PhD , Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute Ali Nawaz Khan, MBBS, FRCP, FRCR, is a member of the following medical societies:

27. USATODAY.com - Fashion Maven Steven Cojocaru Gets Kidney Transplant Redcarpet fashion maven Steven Cojocaru has undergone a successful kidney transplant. Cojocaru, who has polycystic kidney disease, said in a http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

28. Polycystic Kidney Disease polycystic kidney disease in Persian cats culminates in chronic renal failure polycystic kidney disease in a cat. J Small Anim Pract 18663666, 1977 http://www.netcat.org/pkd.html

$nbsp; Polycystic Kidney Disease by Colleen Power Is your cat drinking a lot of water? Does it visit the litter pan a bit too often? In 1978, my three year old white Persian stud began exhibiting these symptoms one day. Each time I passed the bathroom, there he was in the litter pan. After the third time past the door, with him back in the litter pan, I immediately thought, renal blockage. Whipped him up and over to the vet. That was not the problem. He was simply urinating too frequently. So frequently in fact that the vet called it "Polyuria." There was no blockage, no crystal formations in the bladder. He was simply urinating frequently, to the extent that within six hours, he had become dehydrated. The vet pumped him full of fluids, peritoneally(through the abdominal wall) He did x-rays to look for tumors. He then gave me the bad news. The cat likely had a progressive kidney disease that they didnt know much about, called Polycystic Kidney Disease. The cats would experience episodes of polyuria over a one year period before succumbing to the disease. Upon autopsy, they would find lesions on the kidneys, the cause was not known, but the disease was progressive, and the diagnosis: incurable. However, my cat could go home, live a happy, but short life, with increasingly frequent episodes, before he would eventually die. Supportively he received renal tablets(Renaseptic), and of course, some antibiotics. Apollo was fine for six months. I did not stress him with breedings. In fact, I was in the middle of moving and had placed nearly all of the cats, except Apollo and my two folds.

29. Glenn Foley Wings Foundation Glenn Foley, a veteran NFL quarterback, and his foundation have created this site to help educate and inspire others to help fight polycystic kidney Disease. http://www.wings4pkd.org/

30. Feline Symposium - Polycystic Kidney Disease In Cats Autosomal dominant polycystic kidney disease (PKD) is the most common genetic disease of human polycystic kidney disease in a family of Persian cats. http://www.netcat.org/symposium/PKD.html

Polycystic Kidney Disease in Cats Susan Newell, DVM, MS Diplomate, American College of Veterinary Radiology College of Veterinary Medicine Polycystic Kidney Disease in Cats Autosomal dominant polycystic kidney disease (PKD) is the most common genetic disease of human beings, and has recently been recognized in cats. This disease is characterized by progressive development of fluid filled cysts within the kidneys, which distort the normal renal architecture and can lead to renal failure in many affected animals. The Persian breed and other breeds of Persian heritage are frequently affected. The simplest and most accurate method of identifying affected cats has been abdominal ultrasound, where the cysts appear as black round structures with acoustic enhancement within the renal cortex and medula. Studies have shown that ultrasound can correctly identify PKD in cats that are only 7 weeks of age. Provided that the cat is 10 months of age or older, over 95% of those cats that are affected with PKD can be accurately identified with ultrasound. Recently, many cat breeders have used ultrasound PKD screening clinics as a means to identify and potentially eliminate this disease from their bloodlines. To date, over 4400 cats in the United States have been evaluated with 37% of these cats diagnosed positive for the disease. This seminar will review the pertinent facts and literature about PKD with particular emphasis on diagnostic techniques used to evaluate PKD.

31. Our Polycystic Kidney Disease Page A personal site about polycystic kidney disease with chat room for sharing and support. http://www.geocities.com/HotSprings/5291/

Sign My Guestbook View My Guestbook You are the . person to view this page since 1/1/99 This site is a better place to be because of-My Mom! Thanks Mom!!! Last modified 1/1/99 This PKD Ring site is owned by Mary Elizabeth Jones

32. Polycystic Kidney Disease - Symptoms, Diagnosis & Treatment - Nephrologychannel The primary symptom of Autosomal Dominant PKD is pain in the abdomen, back, or side. Symptoms of Autosomal Recessive PKD (infantile PKD) are enlarged cystic http://www.nephrologychannel.com/polycystic/symptoms.shtml

Home Search SiteMap Ask the Dr. ... Medical Store POLYCYSTIC KIDNEY DISEASE Overview Types Causes Diagnosis ... Treatment CONDITIONS Acute Glomerulonephritis (AGN) Acute Interstitial Nephritis (AIN) Acute Renal Failure (ARF) Acute Tubular Necrosis (ATN) Anemia Chronic Renal Failure Diabetic Nephropathy Hematuria ... Nephrotic Syndrome (NS) Polycystic Kidney Disease Microalbuminuria Renal Artery Stenosis (RAS) Renal Vascular Hypertension (RVH) TREATMENT OPTIONS Hemodialysis Peritoneal Dialysis Kidney Transplant RELATED CONDITIONS Electrolyte Imbalance Hemolytic Uremic Syndrome (HUS) Thrombotic Thrombocytopenic Purpura (TTP) RESOURCES Anatomy Clinical Trials Glossary Links ... What Is a Nephrologist? ABOUT US Healthcommunities.com Pressroom Testimonial Bibliography Signs and Symptoms Symptoms of PKD include those that affect the kidney as well as some that affect other organs, including the brain and liver. Though little is known about kidney-related cyst formation in other organs, it is probably related to abnormalities in the glomerular membrane. Autosomal Dominant PKD Abdominal, back, or side pain caused by:

33. Melanie's PKD Page The personal story of experiences with polycystic kidney disease and resources. http://victorian.fortunecity.com/ferndale/686/pkd.html

web hosting domain names photo sharing Melanie's PKD Page This page is all about PKD (Polycystic Kidney Disease). Even though very few people have heard of it, Polycystic Kidney Disease affects 600,000 people in the U.S. alone, and 12.5 million world wide. There are more people with PKD than cystic fibrosis, muscular dystrophy, hemophilia, Downs syndrome and sickle cell anemia combined. Many PKD patients find it useful to have access to the same information as their doctors because many doctors are unfortunately pretty unfamiliar with the disease. I will try to bring you as much information and sources about the disease as possible. If you have any questions about PKD for any reason, or if you know of anyone who has the disease and is looking for more information or for support groups I encourage you to contact any of the sources I have listed here, or to ask me a question . I would also appreciate an email if you have any pertinent information I should add to this page. PKD has been a profound part of my life so far, and will only continue to become more so. Likewise, the information on this page is just the beginning, and will continue to grow as time and research allows. If there is just one person out there that this page might help, I will be grateful for having the opportunity to make a difference. How to help PKD Resources My personal experience with PKD How to help One woman and her dog are traveling across the country by car to raise awareness of PKD and money to help find a cure. You can use the

34. Polycystic Kidney Disease This site contains information about polycystic kidney Disease. http://www.mamashealth.com/poly.asp

Mamashealth.com Home Kidney Disease Glomerulonephritis Kidney Stone Lupus Nephritis Polycystic Kidney Disease ... Wilson's Disease Links Email Mama What is Polycystic Kidney Disease? Polycystic kidney disease (PKD) is an inherited disease characterized by the growth of numerous cysts filled with fluid in the kidneys. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. PKD can also cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. The cysts may also cause pain or may get infected. There are two types of PKD ( autosomal dominant and autosomal recessive Types? Autosomal dominant PKD is inherited. This kind of PKD accounts for about 90 percent of all PKD cases. The term "Autosomal dominant" means that if one parent has the disease, there is a 50 percent chance that the disease will pass to a child. Autosomal recessive PKD is also inherited. This type of PKD is rare. Parents that do not have the disease can have a child with the disease. How can this happen? Ib both parents carry the recessive gene and pass the recessive gene to their child, the child will have two recessive genes and develop the disease.(inherited). What are the symptoms of PKD?

35. Polycystic Kidney Disease (PKD) Access Center Information about polycystic kidney disease, its symptoms, causes and progression. Research and support group. http://www.nhpress.com/pkd/index.html

Polycystic Kidney Disease (PKD) Access Center Welcome ! This site is dedicated to all those who have or know someone who has (had) Polycystic Kidney Disease. Do you know of information or have any ideas that might improve this site? CLICK HERE! Introduction ... HotList (Links) Library What's New Basics Advanced The Kidney Glossary References Click to go to the NEW NOTE: This page is the beginning of another complete rewrite of previous Polycystic Kidney Disease (PKD) pages. Previous versions of this site were started on 21-Aug-98, 15-Dec-97 and 25-May-95. Interested in promoting faster revisions to this site? Contributions as small as $10 can help! Click Here! Jump to NHP Home Page NHP/ mao / 17-Sep-01 / nhp@nhpress.com New Horizons Press Designed by a member of

36. Polycystic Kidney Disease - MayoClinic.com polycystic kidney disease causes clusters of cysts to form in your kidneys. http://www.mayoclinic.com/invoke.cfm?id=DS00245&

37. The Feline PKD Home Page; Information About "Autosomal Dominant Polycystic Kidne Information about Autosomal Dominant polycystic kidney Disease, Feline PKD, Feline polycystic kidney Disease (PKD) has been reported sporadically in the http://www.felinepkd.com/

Home Basic Information, flyer Links to more PKD information Ultrasound Testing Form ... DNA-test This web site was opened to spread information about Feline PKD Autosomal Dominant Polycystic Kidney Disease, in cats. The following information is from January 12, 2005 , on the new DNA-test for PKD in cats! This information was kindly sent to us by Leslie Lyons, PhD, University of California Davis, USA. More information can be found on the page "DNA-test". Marie Thiers Greetings Cat Fanciers! We are happy to announce that the genetic test for PKD is now commercially available! Below and attached is the announcement from the UC Davis Veterinary Genetics Laboratory. Many other laboratories through-out the world have shown interest in offering the test also. Our webpage has information that maybe helpful with selecting a lab for your testing. Please share the information with all interested parties. Our lab is very willing to assist with counseling and interpretations of tests, so please contact us with any concerns. Best regards

38. Polycystic Kidney Disease - Digestion And Digestive-related Information On Medic Digestion information covering the digestion system and related diseases, procedures and tests, medications, and treatments. Produced by doctors. http://www.medicinenet.com/polycystic_kidney_disease/article.htm

document.writeln(''); MedicineNet Home Digestion Home Page > Polycystic Kidney Disease Search Tips Printer-Friendly Format FREE Newsletters Email to a Friend ... Next Polycystic Kidney Disease (PKD) What is Polycystic Kidney Disease? What is autosomal dominant PKD? What are the symptoms of autosomal dominant PKD? How is autosomal dominant PKD diagnosed? ... Polycystic Kidney Disease At A Glance What is Polycystic Kidney Disease? Polycystic kidney disease (PKD) is a disorder that is characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can replace much of the mass of the kidneys, thereby reducing kidney function and leading to kidney failure The kidneys are two organs, each about the size of a fist, that are located in the upper part of the abdomen, towards the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to fail, which usually happens only after many years, the patient requires dialysis or kidney transplantation. About one-half of people with the primary form of PKD progress to kidney failure or end-stage renal disease (ESRD).

39. EID V3 N2: Polycystic Kidney Disease: An Unrecognized Emerging Infectious Diseas Examining the hypothesis that polycystic kidney disease (PKD) is an emerging PKD2, a gene for polycystic kidney disease that encodes an integral http://www.cdc.gov/ncidod/eid/vol3no2/miller.htm

Synopses Polycystic Kidney Disease: An Unrecognized Emerging Infectious Disease? Polycystic kidney disease (PKD) is one of the most common genetic diseases in humans. We contend that it may be an emerging infectious disease and/or microbial toxicosis in a vulnerable human subpopulation. Use of a differential activation protocol for the Limulus amebocyte lysate (LAL) assay showed bacterial endotoxin and fungal (1 3)-ß-D-glucans in cyst fluids from human kidneys with PKD. Fatty acid analysis of cyst fluid confirmed the presence of 3-hydroxy fatty acids characteristic of endotoxin. Tissue and cyst fluid from three PKD patients were examined for fungal components. Serologic tests showed Fusarium Aspergillus, and Candida antigens. IgE, but not IgG, reactive with Fusarium and Candida were also detected in cyst fluid. Fungal DNA was detected in kidney tissue and cyst fluid from these three PKD patients, but not in healthy human kidney tissue. We examine the intertwined nature of the actions of endotoxin and fungal components, sphingolipid biology in PKD, the structure of PKD gene products, infections, and integrity of gut function to establish a mechanistic hypothesis for microbial provocation of human cystic disease. Proof of this hypothesis will require identification of the microbes and microbial components involved and multifaceted studies of PKD cell biology. Examining the hypothesis that polycystic kidney disease (PKD) is an emerging infectious disease and/or microbial toxicosis in a vulnerable population of humans must begin with a review of the conceptual tools that relate disease etiology and progression to the identification of microbes, their cellular components, and shed toxins in affected persons (

40. Polycystic Kidney Disease CHC Wausau Hospital s Medical Library and Patient Education Center provides research services and healthcare information to physicians, http://www.chclibrary.org/micromed/00061240.html

Main Search Index Definition Description Diagnosis ... Resources Polycystic kidney disease Definition Polycystic kidney disease (PKD) is an incurable disorder characterized by the formation of several or many fluid-filled cysts that: Replace healthy kidney tissue Enlarge the kidneys and impair their function Often cause kidney failure. PKD is almost always inherited. In about 10 of every 100 cases, the disease is caused by a defective gene that is not inherited. Description The most common of all life-threatening, genetic diseases, PKD affects at least two of every 10,000 people. A child who inherits the PKD gene from either parent has a 50% chance of developing the disease. A healthy kidney is about the same size as a human fist. PKD cysts, which can be as small as the head of a pin or as large as a grapefruit, can expand the kidneys until each one is bigger than a football and weighs as much as 38 pounds. Types of PKD Babies born with infantile PKD are often born dead. Few of these children survive for more than two years, and many of them die in infancy. PKD is much more common in adults than in children. Symptoms usually start to appear between the ages of 30-50, and, though organ deterioration progresses more slowly than it does in children, untreated disease eventually causes kidney failure.

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