61. Turkish Journal Of Haematology In this report, we present a patient with poems syndrome who had severe polyneuropathyand We present a case of asecretory poems syndrome with multiple http://www.tjh.com.tr/text.php3?id=158

62. Blackwell Synergy J Cutan Pathol, Vol 32, Issue 6, Pp. 449-452 Solitary glomeruloid haemangioma without poems syndrome Glomeruloid haemangiomasappear to be specific to poems syndrome, because they have not been http://www.blackwell-synergy.com/doi/abs/10.1111/j.0303-6987.2005.00353.x

63. Blackwell Synergy - Cookie Absent He was first diagnosed with poems syndrome in November 2003. A diagnosis ofpoems syndrome based on the clinical manifestations and laboratory findings http://www.blackwell-synergy.com/doi/abs/10.1111/j.1368-504X.2005.00343.x

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64. Haema/Áßìá We present a case of poems syndrome, a rare multisystem disorder characterized by poems syndrome represents less than 2% of plasma cell dyscrasias. http://www.mednet.gr/eae/haema/h54-10.htm

HAEMA (ÁÉÌÁ) The Journal of the Hellenic Society of Haematology Journal's Home Page Volume 5, Issue 4 Volume 5, Issue 3 Volume 5, Issue 2 ... Volume 1, Issue 1 4 Papadiamantopoulou str. 115 28 Athens GREECE Tel.-FAX: +30210 7211806 E-mail: eae@hol.gr POEMS syndrome: a case report Kostas Zervas , Angelos Tokmaktsis , Maria Papaioannou , Vasiliki Bakaloudi , Kalliopi Pazaitou , Norma Vavatsi , John Christakis Department of Haematology, Department of Endocrinology, inTheagenioly Cancer Hospital, Thessaloniki, Greece Haema 2002; 5(4): 337-340 Abstract. Key words: POEMS syndrome • multiple myeloma Correspondence: Kostas Zervas, MD, 16 C. Kotta str., 55236, Thessaloniki, Greece, Tel.:+302310.898615, +302310.346446, Fax:+302310.898614. Full text (213 Kb)

65. Poems Syndrome: A Case Report. poems syndrome a case report. Neurology India. 1996 June; 44(2) 824 poems syndrome/DI; poems syndrome/ET; poems syndrome/BL; poems syndrome/UR; http://medind.nic.in/imvw/imvw12935.html

Extracted from IndMED Garg RK; Singh YP; Kar AM; Dwivedee S Department of Neurology, King George's Medical College, Lucknow - 226 003, India. Poems syndrome: a case report. Neurology India. 1996 June; 44(2): 82-4 ABSTRACT: A case of POEMS syndrome is being reported. The case had all the features which are essential for the diagnosis. Agarose gel electrophoresis revealed monoclonal band in gamma region. However, we could not establish osteosclerotic myeloma as a case of this syndrome. KEYWORDS: POEMS Syndrome/DI; POEMS Syndrome/ET; POEMS Syndrome/BL; POEMS Syndrome/UR; Multiple Myeloma; India; Case Report; Human; Male; Adult Record Identifier: NM000604

66. POEMS Syndrome Associated With Solitary, Osteolytic Plasmacytoma: A Case Report. KEYWORDS. poems syndrome/CO; poems syndrome/DI; Plasmacytoma/DI; Osteolysis/DI;Case Report; India; Human; Male; Adult. Record Identifier NM000724. http://medind.nic.in/imvw/imvw14853.html

Extracted from IndMED Singh G; Sawhney IMS; Bhansali A; Verma S; Chopra JS Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India. POEMS syndrome associated with solitary, osteolytic plasmacytoma: a case report. Neurology India. 1995 Mar; 43(1): 38-41 ABSTRACT: POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, M protein and Skin changes) syndrome in a patient with solitary osteolytic plasmacytoma has been reported in this communication. He presented with a demyelinating polyneuropathy, lytic lesion in the left femur and hypogonadism. Serum protein electrophoresis, urine Bence-Jones protein and multiple bone marrow aspirations were negative for the presence of a myeloma. A biopsy from the lytic lesion confirmed the diagnosis of plasmacytoma. KEYWORDS: POEMS Syndrome/CO; POEMS Syndrome/DI; Plasmacytoma/DI; Osteolysis/DI; Case Report; India; Human; Male; Adult Record Identifier: NM000724

67. POEMS Syndrome Synonyms, Eastern Carolina poems syndrome Synonyms University Health Systems of Eastern Carolina servestarboro, ahoskie, edento, winsor, maxhead, dear county, outebanks counties in http://www.uhseast.com/113927.cfm

Health News Health Library Health Topics Healthy Living ... Nutrition Information on diseases and health concerns, including symptoms, treatment options, and prevention. POEMS Syndrome Synonyms Disorder Subdivisions General Discussion Resources ... For a Complete Report Important It is possible that the main title of the report POEMS Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Crow-Fukase Syndrome PEP Syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Shimpo syndrome Takatsuki syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Disorder Subdivisions None General Discussion POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects. Common symptoms include progressive weakness of the nerves in the arms and legs, an abnormally enlarged liver and/or spleen (hepatosplenomegaly), abnormally darkening of the skin (hyperpigmentation) and excessive hair growth (hypertrichosis). Endocrine abnormalities such as failure of the ovaries and testes (gonads) to function properly (primary gonadal failure) and diabetes mellitus type I may be present. Specific endocrine abnormalities associated with POEMS syndrome vary from case to case.

68. Nature Clinical Practice Oncology | COX2-related Multicentric Mixed-type Castlem poems syndrome, also known as CrowFukase syndrome, is associated with a groupof disorders known as monoclonal gammopathies or plasma cell dyscrasias, http://www.nature.com/ncponc/journal/v2/n7/full/ncponc0219.html

@import "/common/style/layout.css";/* do not edit this stylesheet */ @import "/common/style/main.css";/* do not edit this stylesheet */ @import "/clinicalpractice/style/layout_group.css";/* do not edit this stylesheet */ @import "/clinicalpractice/style/group.css";/* do not edit this stylesheet */ @import "/ncponc/style/site.css";/* edit this stylesheet only */ Accessibility statement Jump to main content Jump to main navigation Jump to search ... ABOUT NPG E-MAIL: PASSWORD Save password Forgotten password? MY ACCOUNT E-ALERTS SUBSCRIBE ... REGISTER Text to search for Advanced search Home Archive Vol 2 No 7 ... Case Study Summary Case Study Nature Clinical Practice Oncology doi COX2-related multicentric mixed-type Castleman's disease in a young man Jie Liu*, Shuang Han, Jie Ding, Kaichun Wu, Jiyan Miao and Daiming Fan* Correspondence *State Key Laboratory for Cancer Biology, Department of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China Email jieliu@fmmu.edu.cn or Email fandaim@fmmu.edu.cn

69. No Nephropathy In Type 2 Diabetic Patient With POEMS Syndrome With An Elevated P Here, we present a case of POEMS (CrowFukase) syndrome with Type 2 diabetes,which was associated with elevated plasma VEGF level, but no sign of diabetic http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/10227378.html

No nephropathy in Type 2 diabetic patient with POEMS syndrome with an elevated plasma VEGF Vascular endothelial growth factor VEGF ) is considered to have a role in the pathogenesis of diabetic retinopathy. Recent experimental observations that anti-VEGF neutralizing antibody fully abolished the hyperfiltration and the increase in urinary albumin excretion suggested the contribution of VEGF to the development of diabetic nephropathy , as well. Here, we present a case of POEMS (Crow-Fukase) syndrome with Type 2 diabetes, which was associated with elevated plasma VEGF level, but no sign of diabetic nephropathy The findings obtained from this case did not support the hypothesis that VEGF may enhance the development of diabetic nephropathy iHOP - Information Hyperlinked over Proteins Robert Hoffmann

70. The American Journal Of Surgical Pathology - UserLogin Castleman s disease, reported to be associated with poems syndrome,5 was alsonot apparent. Glomeruloid hemangioma in poems syndrome shows two different http://www.ajsp.com/pt/re/ajsp/fulltext.00000478-200402000-00015.htm

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71. The American Journal Of Surgical Pathology - UserLogin poems syndrome definitions and longterm outcome. Blood. Castleman disease;poems syndrome; follicular dendritic cells; subcutis; soft tissue; http://www.ajsp.com/pt/re/ajsp/fulltext.00000478-200405000-00002.htm

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72. POEMS SYNDROME asymétrique ou unilatérale) se manifestant par une tuméfaction centrée par http://look4.free.fr/syndrome/poems.htm

Connexion Annonces QCM Ajouter Testez Iconographie choisir une rubrique Alternative Med Allergologie Anatomopatho Anesthésie Rea Cardiologie Dermatologie Endocrinologie Enzymopathie Gastrologie Gynécologie Hématologie Immunopathie Infectieux Neurologie Ophtalmologie O.R.L Pneumologie Pédiatrie Psychiatrie Radiodiagnostic Rhumatologie Uro-Nephrologie Urologie néphrologie Sommaire POEMS SYNDROME Définition : Affection dénommée par un acronyme signifiant P Polyneuropathie périphérique (polyradiculonévrite chronique) O Organomégalie (hépatomégalie, splénomégalie, lymphadénopathie) E Endocrinopathie (impuissance, hypogonadisme, aménorrhée, gynécomastie, diabète, hypothyroïdie) M Monoclonale gammapathie (presque toujours de type IgG l ou IgA l), fréquemment associée à des lésions osseuses (plasmocytome) S Skin abnormalities , anomalies de la peau (hyperpigmentation, hypertrichose, hyperhidrose) Pronostic meilleur que celui du myélome multiple Traitement : Du plasmocytome (chirurgie radiothérapie) et chimiothérapie . ME DECINE Dr. sam .

73. Rezidivierende Zerebrovaskuläre Insulte - Manifestation Des POEMS-Syndroms? (Re Translate this page Recurrent strokes – manifestation of the poems syndrome? The poems syndromeis a multisystem disorder characterised by polyneuropathy, organomegaly, http://www.smw.ch/archive/1998/128-26-280-98.html

Kasuistik Peer reviewed article Cet article n'a pas été résumé en français Das POEMS-Syndrom ist eine Multisystemerkrankung mit Polyneuropathie, Organomegalie, Endokrinopathie, Plasmazelldyskrasie und Hautveränderungen. Nebst vielen weiteren Manifestationen kann es im Rahmen dieses seltenen Syndroms auch zu einer Makroangiopathie und zu akuten arteriellen Verschlüssen kommen. In der Literatur wurde solchen Gefässmanifestationen bislang nur wenig Beachtung geschenkt, und die meisten Fallbeschreibungen betreffen Befall der Koronar- und Extremitätenarterien; die Assoziation mit rezidivierenden zerebrovaskulären Insulten ist bisher noch nicht beschrieben worden. Wir berichten von einem 59jährigen Patienten mit dem Vollbild eines POEMS-Syndroms, welches mit einem multizentrischen Morbus Castleman einherging. Trotz Fehlen vaskulärer Risikofaktoren traten Myokardinfarkte und ischämische Zehennekrosen auf, und es kam zu rezidivierenden ischämischen Insulten unter oraler Antikoagulation. Zerebrovaskuläre Insulte stellen somit wahrscheinlich eine weitere Komplikation des POEMS-Syndroms dar. The POEMS syndrome is a multisystem disorder characterised by polyneuropathy, organomegaly, endocrinopathy, plasma cell dyscrasia and skin changes. Along with many further manifestations this rare syndrome may also include macroangiopathy and acute vascular obliteration. In the literature such vascular problems have received only little attention and most case reports refer to involvement of the coronary and lower limb arteries. To our knowledge, the association with recurrent strokes has not been described.

74. Med Bull Miscalleneous Dermatomyozitis and poems syndrome (polyneurophathy, organomegaly,endocrinopathy, monoclonal M component and skin changes) (4,6,8,9,11). http://www.istanbul.edu.tr/istanbultip/mecmua/medmecmua/med-99-1/09.htm

Med Bull. Istanbul 32:1 (1999) A CASE OF HYPERTRICHOSIS UNIVERSALIS CONGENITA (AMBRAS SYNDROME) Kývanç ÇEFLE*, Þükrü PALANDUZ*, Þükrü ÖZTÜRK*, Kerim GÜLER**, Gökay BOZKURT*** SUMMARY Although hypertrichosis is considered by many physicians as a clinical finding of cosmetic significance only, it is a physical sign of many serious acquired and hereditary diseases and may be the presenting symptom. Herein we describe a case of Ambras syndrome where hypertrichosis is the sole complaint of the patient. Key Words: Ambras syndrome, hypertrichosis, hirsutism. INTRODUCTION Althought hypertrichosis is a physical finding of many hereditary diseases, its chief clinical significance comes from the fact that it is a feature of many serious acquired diseases which are much more common. Hirsutism is another term which is used to denote excessive hairy growth, but as will be explained below, it is a different clinical situation and should not be confused with hypertrichosis. Herein we describe a case of Ambras syndrome and emphasize the clinical importance of hypertrichosis which is usually neglected in the clinical practice. CASE REPORTS A 15-year old girl was admitted to our hospital due to excessive and generalized hair growth which was evident immediately after brith. She was reported to have 3 febril convulsions during early childhood. Her mother had an uneventful pregnancy with no drug exposure. Her parents were first cousins and her family did not involve any members with similar physical findings. Although there were no dysmorphologic findings in the physical examination, black, coarse hairy growth involving her entire body, especially on the forearms was noted (Fig 1,2 and 3). The development of secondary sex characters were normal.

75. ASCO - Browse By Meeting - Autologous Peripheral Blood Stem Cell Transplant (APB Abstract, Background poems syndrome is a rare clonal plasma cell disorder Further testing of APBSCT for poems syndrome in a prospective multicenter http://www.asco.org/ac/1,1003,_12-002636-00_18-0023-00_19-00104476,00.asp

HOME ABOUT ASCO PRESS CENTER STATE AFFILIATES ... Career Resources Pay Membership Dues, Membership Directory, Drug Database, Update Your Profile username password Remember Me Forgot your password? Create a guest account BECOME A MEMBER Journal of Clinical Oncology Journal of Oncology Practice The ASCO Foundation People Living With Cancer BECOME A SPONSOR The remember me feature is an automatic login process which creates a cookie on the hard drive of your computer containing your username and password, thereby avoiding the need to enter them upon subsequent visits to asco.org. DO NOT select this option if you share this computer with others since personal or member only information will be accessible by other users. For addition information please review our . Click OK to keep the Remember Me option, or click Cancel to remove it. When you are done, click the LOGIN button to continue with the login Process . Home Abstracts Browse by Meeting Meeting: 2003 ASCO Annual Meeting Printer Friendly Bookmark Category: Transplantation SubCategory: Autologous Bone Marrow Transplantation Autologous peripheral blood stem cell transplant (APBSCT) in patients with POEMS syndrome.

76. Mayo Clinic Proceedings Pulmonary hypertension in poems syndrome a new feature mediated by cytokines . poems syndrome definitions and longterm outcome. Blood. http://www.mayoclinicproceedings.com/inside.asp?AID=550&UID=

77. Diagnosis & Therapy extra medullary plasmacytoma, osteosclerotic myeloma (poems syndrome), which is suggestive of the poems syndrome (polyneuropathy, organomegaly, http://www.clevelandclinic.org/myeloma/DiagnosisAndTreatmentOfMultipleMyeloma.ht

Multiple Myeloma Research Center DIAGNOSIS AND TREATMENT OF MULTIPLE MYELOMA AND OTHER PLASMA CELL DISORDERS MULTIPLE MYELOMA: Multiple myeloma is a prototype of a group of conditions known as plasma cell neoplasm's. Plasma cell neoplasm's are a group of related disorders each of which is associated with proliferation and accumulation of immunoglobulin-secreting cells that are derived from the B-cell series of immunocytes. Monoclonal components occur in both the malignant plasma cell disorders, that is say, multiple myeloma, Waldenstrom's macroglobulinemia, solitary bone plasmacytoma, extra medullary plasmacytoma, osteosclerotic myeloma (POEMS Syndrome), amyloidosis, and heavy chain disease, as well as in the clinically unclear monoclonal gammopathy of undetermined significance/smoldering multiple myeloma. PRESENTING SIGNS AND SYMPTOMS: The clinical features of multiple myeloma develop from tissue damage by multiple bone tumors, complications from the monoclonal component, and an increased vulnerability to infections due to depressed normal immunoglobulin levels. These complications provide the first clues to the diagnosis and form the basis for defining the stage and prognosis. Subjective: Skeletal System Bone pain is the most common symptom resulting from pathologic fractures.

78. On-line Archives Of Rheumatology In poems syndrome cutaneous changes are characterized by hyperpigmentation, The spectrum of the poems syndrome. N Engl J Med. 1992; 327 191923 http://www.archrheumatol.net/1999/0016.html

Urticaria, osteocondensation and monoclonal gammopathy (Schnitzler Syndrome): a new case report G.Peronato, P.De Sandre, *E.Bonoldi 3rd Division of Medicine - *Division of Pathology Ospedale S. Bortolo, Vicenza, Italy On-line Arch Rheumatol 1999; 3: 4 published on December 27, 1999 Abstract We described the case of a 39-year-old man with a five year history of low back pain, osteocondensation of the fifth lumbar vertebra and IgM monoclonal gammpathy. Bone biopsy of fifth lumbar vertebra showed some features of Paget's disease of the bone and therefore treatment with biphosphonates was initiated, with a significant reduction of back pain. Six months later the patient presented with the first episode of a non-pruritic urticaria, accompanied by a high fever, which eventually became recurrent. The association of urticaria, recurrent fever, painful osteocondensation and IgM monoclonal gammpathy was described for the first time by L. Schnitzler in 1974 and since then only 49 cases have been reported. Although no adequate therapy has been reported, biphosphonates treatment was effective on bone pain in our patient.

79. Portal Toolkit Invalid Site URL September 1996, 943 The poems syndrome report of two We report twowomen patients affected by poems syndrome (polyneuropathy, organomegaly, http://ppv.ovid.com/pt/re/obes/fulltext.00000132-199609000-00026.htm

Sorry, the URL specified, http://ppv.ovid.com:80/pt/re/obes/fulltext.00000132-199609000-00026.htm , is invalid. To go to site for "OvidPPV" please click here http://ppv.ovid.com To go to site for "Acta Neurologica Scandinavica" please click here http://www.lwwonline.com To go to the LWW Online site, please click here http://www.lwwonline.com Thank you

80. Portal Toolkit Invalid Site URL poems syndrome, also known as CrowFukase syndrome, is a multi-system disease, poems syndrome may comprise complete and incomplete forms. http://ppv.ovid.com/pt/re/obes/fulltext.00000132-200508000-00010.htm

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