21. POEMS Syndrome Solitary glomeruloid haemangioma without poems syndrome. Glomeruloid haemangiomasappear to be specific to poems syndrome, because they have not been http://www.thedoctorsdoctor.com/diseases/poems.htm

Background POEMS syndrome stands for: Polyneuropathy Organomegaly Endocrinopathy Monoclonal gammopathy Skin lesions OUTLINE Epidemiology Disease Associations Pathogenesis Laboratory/Radiologic/ ... Internet Links EPIDEMIOLOGY CHARACTERIZATION SYNONYMS None INCIDENCE Rare AGE-RANGE AND MEDIAN May be in childhood SEX (MALE:FEMALE) Males favored LABORATORY/ RADIOLOGIC/ OTHER TESTS CHARACTERIZATION Monoclonal protein spike Level is low and usually IgG or IgA HISTOLOGICAL TYPES CHARACTERIZATION Bone marrow Often osteosclerotic myeloma with multiple sclerotic bony lesions admixed with the plasma cells Almost all patients have lamba light chains SKIN Glomeruloid hemangiomas Solitary glomeruloid haemangioma without POEMS syndrome. Velez D, Delgado-Jimenez Y, Fraga J. Department of Pathology, 'La Princesa' University Hospital, Madrid, Spain. J Cutan Pathol. 2005 Jul;32(6):449-452. Abstract quote Background: The term 'glomeruloid haemangioma' was coined by Chan et al. for a histologically distinctive cutaneous haemangioma, which they considered a specific cutaneous marker for POEMS syndrome. Glomeruloid haemangiomas appear to be specific to POEMS syndrome, because they have not been reported in patients without this syndrome. Methods: We report on an 86-year-old man without POEMS syndrome and with a solitary red papule on the face.

22. Erythema Elevatum Diutinum poems syndrome, steroiddependent diabetes mellitus, erythema elevatum diutinum, poems syndrome is a rare synopsis of different multisystemic disorders http://www.thedoctorsdoctor.com/diseases/eed.htm

Background This is a rare vasculitis that classically presents with plaque-like violaceous lesions on the extensor surfaces of the extremities and the trunk. Recently, interesting histopathological variants have been described in AIDS patients. OUTLINE Epidemiology Disease Associations Acro-osteolysis Celiac disease Crohn's disease HIV-1 Hyperimmunoglobulinemia D IgA paraproteinemia Lymphoma Myelodysplasia POEMS syndrome Pyoderma gangrenosum Relapsing polychondritis Rheumatoid arthritis Wegener's granulomatosis Pathogenesis Laboratory/Radiologic/ Other Diagnostic Testing Gross Appearance and Clinical Variants ... Commonly Used Terms EPIDEMIOLOGY CHARACTERIZATION SYNONYMS EED INCIDENCE Uncommon DISEASE ASSOCIATIONS CHARACTERIZATION ACRO-OSTEOLYSIS Erythema elevatum diutinum with extensive acro-osteolysis. Ellabban A, Schumacher HR Jr. Division of Rheumatology, University of Pennsylvania School of Medicine, Philadelphia, USA. J Rheumatol 1997 Jun;24(6):1203-5 Abstract quote

23. POEMS Syndrome poems syndrome is an extremely rare multisystem disorder. POEMS is an acronymthat stands for (P)olyneuropathy, http://webcenter.health.webmd.netscape.com/hw/brain_nervous_system/nord789.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report POEMS Syndrome Important It is possible that the main title of the report POEMS Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Crow-Fukase Syndrome PEP Syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Shimpo syndrome Takatsuki syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Disorder Subdivisions None General Discussion POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects. Common symptoms include progressive weakness of the nerves in the arms and legs, an abnormally enlarged liver and/or spleen (hepatosplenomegaly), abnormally darkening of the skin (hyperpigmentation) and excessive hair growth (hypertrichosis). Endocrine abnormalities such as failure of the ovaries and testes (gonads) to function properly (primary gonadal failure) and diabetes mellitus type I may be present. Specific endocrine abnormalities associated with POEMS syndrome vary from case to case.

24. Symptoms Of POEMS Syndrome Get valuable information about symptons, diagnosis and treatment of poems syndrome. http://www.clearleadinc.com/site/poems-syndrome.html

Home Related Articles Search in this category Causes of POEMS Syndrome ... Treatment of POEMS Syndrome POEMS Syndrome Diagnosis POEMS syndrome, a rare multi systemic disease, is more prevalent among men than women. POEMS syndrome is considered rare but note that the presence of this syndrome could go unrecognized in many cases. POEMS syndrome usually affects people in their fifth or sixth decades. It is reported that the median survival period for patients with POEMS syndrome is 8 years. Causes of POEMS Syndrome Plasma cell disorder is considered to be the main cause of POEMS syndrome. It is still unclear as to why plasma cells in some dyscrasias produce factors that cause the POEMS syndrome. This syndrome is associated with MGUS, osteosclerotic myeloma and Waldenstrom macroglobulinemia. Symptoms of POEMS Syndrome The POEMS syndrome is the acronym for the most common symptoms of the syndrome: P: Peripheral neuropathy, which includes tingling, numbness and the weakening of hands and feet. O: Organomegaly that includes large organs like the lymph nodes, liver and spleen. E: Endocrinopathy that causes abnormality in hormone levels.

25. Penn State Faculty Research Expertise Database (FRED) , A multisystemic disorder characterized by a Crow Fukase Syndrome, Syndrome, CrowFukase. Syndrome, POEMS, Syndrome......poems syndrome. http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D016878

26. Penn State Faculty Research Expertise Database (FRED) peripapillary choroidal neovascularization, and poems syndrome. endocrinopathy,monoclonal gammopathy, and skin changes (POEMS) syndrome, http://fred.hmc.psu.edu/ds/retrieve/fred/publication/11812439

27. POEMS Syndrome poems syndrome is an extremely rare multisystem disorder. POEMS is an acronymthat stands for (P)olyneuropathy, disease affecting many nerves; http://www.bchealthguide.org/kbase/nord/nord789.htm

var hwPrint=1;var hwDocHWID="nord789";var hwDocTitle="POEMS Syndrome";var hwRank="1";var hwSectionHWID="nord789-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. POEMS Syndrome Important It is possible that the main title of the report POEMS Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Crow-Fukase Syndrome PEP Syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Shimpo syndrome Takatsuki syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Disorder Subdivisions None General Discussion POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects. Common symptoms include progressive weakness of the nerves in the arms and legs, an abnormally enlarged liver and/or spleen (hepatosplenomegaly), abnormally darkening of the skin (hyperpigmentation) and excessive hair growth (hypertrichosis). Endocrine abnormalities such as failure of the ovaries and testes (gonads) to function properly (primary gonadal failure) and diabetes mellitus type I may be present. Specific endocrine abnormalities associated with POEMS syndrome vary from case to case.

28. Log In Problems poems syndrome, also known as the CrowFukase syndrome, was first reported in 1956. http://www.medscape.com/viewarticle/409056

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29. Log In Problems One patient with plasma cell CD had poems syndrome. Followup has been from 2 to14 years. No patients have had development of lymphoma or plasmacytoma http://www.medscape.com/viewarticle/410775_print

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30. Blood -- Sign In Page poems syndrome definitions and longterm outcome. Blood. 2003;101 2496-2506 . Hayashi T. poems syndrome and VEGF. Intern Med. 2004;43 1014. http://www.bloodjournal.org/cgi/content/full/106/3/1135

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Blood Online. Full Text Bevacizumab therapy for POEMS syndrome Badros et al. Blood. To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$25.00 Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired. Sign Up Subscribe to the Journal - Subscribe to the print and/or online journal. Access for Patients Access for Patients - Patients desiring immediate access should contact the journal. This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Rights and Permissions PubMed PubMed Citation Articles by Badros, A.

31. High-dose Therapy And Autologous Blood Stem Cell Transplantation In POEMS Syndro Diagnosis of poems syndrome was considered in patients who presented with plasmacell Table 1. Main characteristics of patients with poems syndrome http://www.bloodjournal.org/cgi/content/full/99/8/3057

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Rights and Permissions PubMed PubMed Citation Articles by Jaccard, A. Articles by Fermand, J.-P. Related Collections Transplantation Brief Reports Clinical Observations, Interventions, and Therapeutic Trials Related Letter in Blood Online Blood, 15 April 2002, Vol. 99, No. 8, pp. 3057-3059 BRIEF REPORT High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome Arnaud Jaccard Bruno Royer Dominique Bordessoule Jean-Claude Brouet and Jean-Paul Fermand Abstract Top Abstract Introduction Study design Results and discussion References We treated 5 patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and multifocal bone lesions or diffuse bone marrow plasmacytic infiltration with high-dose therapy (HDT) and autologous blood stem cell transplantation. In all cases, the treatment produced

32. Poems Syndrome - Patient UK poems syndrome Patient UK. A directory of UK health, disease, illness andrelated medical websites that provide patient information. http://www.patient.co.uk/showdoc/40001494/

PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Poems syndrome Variant form of multiple myeloma (malignant proliferation of plasma cell in bone marrow causing skeletal destruction leading to bone pain and pathological fractures). An acronym which stands for: P polyneuropathy O - organomegaly E endocrinopathy M - M-protein S - skin changes Epidemiology Incidence Uncommon Presentation Signs Characteristic feature is a chronic inflammatory demyelinating neuropathy causing mainly motor disability. Hepatomegaly found in approximately half of patients. Hyperpigmentation and hypertrichosis are common. May be angiomatous lesions of trunk. Gynaecomastia and atrophic testes. Investigations Management If osteosclerotic lesions in limited area - radiotherapy If osteosclerotic lesions widespread - chemotherapy or autologous stem cell transplantation. References Used Kyle RA in Oxford Textbook of Medicine, 4th Edition. Eds; Warrell DA et al. OUP 2003.

33. Ivanhoe's Medical Breakthroughs - Discussion Groups poems syndrome kidslaw@bellsouth.net 06/25/05; Degenerative Disease - frank06/21/05; No Subject - veraone@webtv.net 06/14/05 http://ivanhoe.com/discussion/p_discussion.cfm?forumID=84&action=msglist

34. Ivanhoe's Medical Breakthroughs - Discussion Groups Discussion Reader s Request PostHodgkin s Treatment From kidslaw@bellsouth.netDate 06/25/2005 Subject poems syndrome http://ivanhoe.com/discussion/p_discussion.cfm?forumid=84&messageID=37333&action

35. Hill Health Topics A-Z - POEMS Syndrome poems syndrome. National Organization for Rare Disorders. Important It is possiblethat the main title of the report poems syndrome is not the name you http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord789&SE

36. POEMS Syndrome Topic - Unified Search Environment poems syndrome Topic Tree poems syndrome MSH/MH/D016878 MSH/PM/D016878CrowFukase Syndrome MSH/EP/D016878 MSH/PM/D016878 MSH/PM/D016878 http://www.use.hcn.com.au/portals/shared/subject.`POEMS Syndrome`/home.html

POEMS Syndrome Topic Tree Definition: A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62) Synonyms and Source Vocabularies: POEMS Syndrome Crow-Fukase Syndrome Takatsuki's Syndrome Congenital Abnormality Abnormalities, Drug-Induced Abnormalities, Multiple Basal Cell Nevus Syndrome Beckwith-Wiedemann Syndrome Bloom Syndrome Cockayne Syndrome ... Congenital neurologic anomalies

37. Poems Syndrome Complete online version of The Encyclopaedia of Medical Imaging including textand images from The Encyclopaedia of Medical Imaging s eight book volumes http://www.amershamhealth.com/medcyclopaedia/medical/Volume III 1/POEMS SYNDROME

financial services our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Poems syndrome, a combination of plasma cell dyscrasia , chronic progressive polyneuropathy, and endocrine abnormalities such as diabetes mellitus . This syndrome is of unknown cause and takes its name from the typical features: polyneuropathy, organomegaly, endocrinopathy, M proteins and skin changes. Numerous other characteristics can be noted. However, patients do not have an increased prevalence of amyloidosis and rarely reveal Bence Jones proteinuria. Bone proliferation occurs at entheses (sites of tendon and ligament attachment to bone). Particularly characteristic are irregular bony excrescences on the posterior elements of the spine and about the sacroiliac and costovertebral joints ( Fig.1 DR/RB The Encyclopaedia of Medical Imaging Volume III 1 Poems syndrome, Fig. 1 AP radiograph of the pelvis in a patient with POEMS syndrome demonstrates numerous sclerotic foci in the pelvis and femora owing to plasma cell myeloma. Corporate Products Financial Services Our Commitment ... Terms of Conditions

38. POEMS Syndrome - St. Joseph Mercy, Ann Arbor Michigan poems syndrome St. Joseph Mercy Health System Hospitals serving Ann Arbor, SEMichigan, Washtenaw County, Livingston County, Wayne County, Oakland County, http://www.sjmercyhealth.org/15121.cfm

@import url(default.css); Online Health Information Health Information - Rare Diseases and Disorders Back to Health Library Print This Page Email to a Friend National Organization for Rare Disorders, Inc. POEMS Syndrome Synonyms Disorder Subdivisions General Discussion Resources ... For a Complete Report Important It is possible that the main title of the report POEMS Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Crow-Fukase Syndrome PEP Syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Shimpo syndrome Takatsuki syndrome Polyneuropathy-organomegaly-endocrinopathy-M protein-skin lesions Disorder Subdivisions None General Discussion POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects. Common symptoms include progressive weakness of the nerves in the arms and legs, an abnormally enlarged liver and/or spleen (hepatosplenomegaly), abnormally darkening of the skin (hyperpigmentation) and excessive hair growth (hypertrichosis). Endocrine abnormalities such as failure of the ovaries and testes (gonads) to function properly (primary gonadal failure) and diabetes mellitus type I may be present. Specific endocrine abnormalities associated with POEMS syndrome vary from case to case.

39. Poems Syndrome - Definition From Biology-Online.org Definition and other additional information on poems syndrome from BiologyOnline.orgdictionary. http://www.biology-online.org/dictionary/poems_syndrome

Forum Tutorials Dictionary Directory ... P poems syndrome poems syndrome (Science: syndrome) A chronic progressive multisystem disorder of obscure aetiology characterised by polyneuropathy organomegaly endocrinopathy monoclonal ... gammopathy and skin changes Search the dictionary About Us Contact Us Link to Us Chemistry ... Equations

40. Pulmonary Hypertension Associated With POEMS Syndrome -- Ribadeau-Dumas Et Al. 9 Both had a history of poems syndrome a few years previously. PulmonaryManifestations of poems syndrome Case Report and Literature Review http://erj.ersjournals.com/cgi/content/abstract/9/8/1760

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Ribadeau-Dumas, S Articles by Wallaert, B Eur Respir J 1996; 9: 1760-1762 ERS Journals Ltd Case Studies Pulmonary hypertension associated with POEMS syndrome S Ribadeau-Dumas, I Tillie-Leblond, C Rose, F Saulnier, JL Wemeau, PY Hatron, and B Wallaert This article has been cited by other articles: A. Dispenzieri, R. A. Kyle, M. Q. Lacy, S. V. Rajkumar, T. M. Therneau, D. R. Larson, P. R. Greipp, T. E. Witzig, R. Basu, G. A. Suarez, R. Fonseca, J. A. Lust, and M. A. Gertz POEMS syndrome: definitions and long-term outcome Blood, April 1, 2003; 101(7): 2496 - 2506. [Abstract] [Full Text] [PDF] B. Mokhlesi and M. Jain

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