1. NORD - National Organization For Rare Disorders, Inc. Offers the synonyms, a general discussion and resources. http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=POEMS Syndrom

2. EMedicine - POEMS Syndrome : Article By Wingfield Rehmus, MD, MPH poems syndrome Polyneuropathy, organomegaly, endocrinopathy, monoclonalgammopathy, and skin changes (POEMS) syndrome is a rare multisystemic disease that http://www.emedicine.com/derm/topic771.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Internal Medicine POEMS Syndrome Last Updated: July 10, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: Crow-Fukase syndrome, Takatsuki syndrome, PEP, polyneuropathy endocrinopathy plasma cell dyscrasia, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Wingfield Rehmus, MD, MPH , Co-Director of Clinical Trials, Clinical Instructor, Department of Dermatology, Stanford University Medical Center Coauthor(s): Alexa Boer Kimball, MD, MPH , Director of Clinical Trials, Department of Dermatology, Brigham and Women's Hospital, Harvard University School of Medicine Wingfield Rehmus, MD, MPH, is a member of the following medical societies: American Academy of Dermatology Editor(s): Neil Shear, MD

3. POEMS Syndrome Background. poems syndrome stands for Polyneuropathy Organomegaly Endocrinopathy Monoclonal gammopathy Skin lesions OUTLINE Epidemiology http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. POEMS Syndrome Treatment Options At Mayo Clinic Information about poems syndrome, what it is, symptoms, diagnosis, treatment and who gets it. http://www.mayoclinic.org/poems-rst/

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services POEMS Syndrome POEMS Syndrome Overview Symptoms Diagnosis Treatment Options ... Medical Services Treatment of POEMS Syndrome at Mayo Clinic (Synonyms: Crow-Fukase syndrome, PEP syndrome, Shimpo syndrome and Takatsuki syndrome) Patients with POEMS syndrome experience an integrated approach to diagnosis and treatment at Mayo Clinic. Working together, Mayo specialists develop a treatment plan based on the patient's needs and health issues. In some cases, patients with POEMS syndrome can receive a bone marrow transplant through Mayo Clinic's Transplant Center. Mayo is active in research on this disorder. Diagnosis POEMS syndrome is so rare that physicians who do not have experience with the disease may miss the diagnosis. Physicians at Mayo Clinic have the skills and experience necessary to diagnose this rare condition. The overgrowth of plasma cells can often be detected by finding an abnormal protein in the blood or urine, by an abnormality on a bone X-ray and/or a bone marrow biopsy. Read more about diagnosis of POEMS Syndrome Treatment Options Because POEMS syndrome is a multisystem disease, hematologists at Mayo Clinic gather neurologists, endocrinologists, radiation oncologists, physical therapists and other specialists to develop a comprehensive treatment approach. Treatment options include radiation therapy, corticosteroids, chemotherapy, a bone marrow transplant, hormone replacement therapy and physical therapy. Read more about

5. POEMS Syndrome Links to information and resources for poems syndrome, a multisystem disorder. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. POEMS Syndrome poems syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. POEMS Syndrome Information Diseases Database poems syndrome,Osteosclerotic myeloma, Disease Database Information. http://www.diseasesdatabase.com/ddb29226.htm

Diseases Database Index Sponsors Contact ... Previous Page POEMS syndrome information Search 2 synonyms or equivalents were found. POEMS syndrome aka/or Osteosclerotic myeloma may cause or feature (Follow link for list.) may be associated with (Follow link for list.) belong(s) to the category of (Follow link for list.) POEMS syndrome: Definition(s) via UMLS Code translations and terms via UMLS POEMS syndrome: specific web sites Send POEMS syndrome to medical search engines (JavaScript enabled browsers only.) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation Valid XHTML 1.0 Served 2005-09-09 15:48:34 CPU 1s. View metadata Last major update 2005-09-03. The medical information here is presented for education, background reading and general interest. The Diseases Database is not a diagnostic or clinical decision-making tool. Please consult your own licensed physician regarding diagnosis and treatment of any medical condition! Content is not asserted complete or error free, please see also our

8. Treatment Of POEMS Syndrome, Mayo Clinic In Rochester, Minn. Information about poems syndrome, what it is, symptoms, diagnosis, treatment and who gets it. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Immune Demyelinating PN poems syndrome Sulfatide antibody associated neuropathy Antibody testing High incidence in Japanese males; Partial poems syndromes http://www.neuro.wustl.edu/neuromuscular/antibody/pnimdem.html

Front Search Index Links ... Patient Info CHRONIC IMMUNE POLYNEUROPATHIES: DEMYELINATING Comparative features: Demyelinating PN Treatment strategies CIDP ... GALOP syndrome GD1a antibody Motor-Sensory neuropathy Multifocal motor neuropathy MAG antibody associated neuropathy Osteosclerotic Myeloma ... Antibody testing Myelinated Axons: Segmental demyelination in Multifocal Motor Neuropathy (MMN) CHRONIC IMMUNE DEMYELINATING NEUROPATHIES COMPARATIVE FEATURES Neuropathy Clinical Features Electrophysiology Antibody M-Protein Treatment CIDP Weakness: Symmetric Onset: 1 to 80 yrs Chronic or Relapsing Motor + Sensory change Slow NCV Conduction Block Distal Latency: Long Slow F-waves Targets Heparan sulfate Class: IgM or IgG Frequency: 20% T-cell immunosuppression Prednisone Cyclosporine A Methotrexate HIG Plasma Exchange Multifocal CIDP Also see: CIDP variants Chronic Weakness: Asymmetric Onset: 15 to 75 yrs Motor + Sensory change Slow NCV Conduction Block Distal Latency: Long Slow F-waves T-cell immunosuppression Prednisone HIG MMN Motor only Asymmetric Onset: 25 to 60 yrs Slowly progressive Motor only Conduction Block Axonal Loss EMG: No paraspinous denervation Targets Co-GM1 or NP-9 Class: IgM Frequency: 80% HIG B-cell immunosuppression Plasma Exchange + Cyclophosphamide Rituxan Anti-MAG Distal; Symmetric

10. EMedicine - POEM Syndrome Article Excerpt By Wingfield Rehmus POEM Syndrome POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes) syndrome is a rare multisystemic disease http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. POEMS Syndrome Treatment Options At Mayo Clinic poems syndrome treatment options at Mayo Clinic include bone marrow transplants. http://www.mayoclinic.org/poems/

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services POEMS Syndrome POEMS Syndrome Overview Symptoms Diagnosis Treatment Options ... Medical Services Treatment of POEMS Syndrome at Mayo Clinic (Synonyms: Crow-Fukase syndrome, PEP syndrome, Shimpo syndrome and Takatsuki syndrome) Patients with POEMS syndrome experience an integrated approach to diagnosis and treatment at Mayo Clinic. Working together, Mayo specialists develop a treatment plan based on the patient's needs and health issues. In some cases, patients with POEMS syndrome can receive a bone marrow transplant through Mayo Clinic's Transplant Center. Mayo is active in research on this disorder. Diagnosis POEMS syndrome is so rare that physicians who do not have experience with the disease may miss the diagnosis. Physicians at Mayo Clinic have the skills and experience necessary to diagnose this rare condition. The overgrowth of plasma cells can often be detected by finding an abnormal protein in the blood or urine, by an abnormality on a bone X-ray and/or a bone marrow biopsy. Read more about diagnosis of POEMS Syndrome Treatment Options Because POEMS syndrome is a multisystem disease, hematologists at Mayo Clinic gather neurologists, endocrinologists, radiation oncologists, physical therapists and other specialists to develop a comprehensive treatment approach. Treatment options include radiation therapy, corticosteroids, chemotherapy, a bone marrow transplant, hormone replacement therapy and physical therapy. Read more about

12. EMedicine - POEMS Syndrome Article By Wingfield Rehmus, MD, MPH poems syndrome Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare multisystemic http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Symptoms Of POEMS Syndrome POEMS is an acronym for the syndrome s most common symptoms To receive adiagnosis of poems syndrome, patients must experience at least the P and the http://www.mayoclinic.org/poems/symptoms.html

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services POEMS Syndrome POEMS Syndrome Overview Symptoms Diagnosis Treatment Options ... Medical Services Symptoms of POEMS Syndrome POEMS is an acronym for the syndrome's most common symptoms: P polyneuropathy: nerve disease (numbness, tingling, and weakness of the hands and feet). O organomegaly: organ enlargement (liver, lymph nodes or spleen). E endocrinopathy: disease affecting hormone-producing glands (sexual development, metabolic functions, thyroid hormones, etc.). M monoclonal gammopathy or monoclonal plasma proliferative disorder: a collection of abnormal blood protein cells. S skin changes: increased skin pigment, increased body hair, thickening of the skin, whitening of the nails, etc. To receive a diagnosis of POEMS syndrome, patients must experience at least the "P" and the "M" as well as either sclerotic (scarring) bone lesions or Castleman disease, a coexisting condition. Patients will typically have at least one other feature (the "O", "E", or "S") as well as some abnormalities listed below. Common abnormalities included in the syndrome include: Fatigue and weakness Edema (swelling of the ankles and legs) Enlarged breast tissue (occurs in both men and women) Generalized aches and pains Ascites (fluid collection in the abdomen) Pleural effusion (fluid collection in the lungs) Increased blood cell counts (increased platelet or red cell count) Changes in vision Home About Mayo Clinic Contact Mayo About This Site ... Search E-mail this Page

14. S000516c - POEMS Syndrome Question What is the poems syndrome? 1 20143022 LINK TO FULLTEXT Neurology. 54(3)7723, 2000 Feb 8. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

15. POEMS Syndrome Links to information and resources for poems syndrome, a multisystem disorder. http://rarediseases.about.com/cs/poemssyndrome/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a70' About Rare / Orphan Diseases Rare Diseases Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Rare / Orphan Diseases newsletter! See Online Courses Search Rare / Orphan Diseases POEMS Syndrome Guide picks A plasma cell dyscrasia (bone marrow disorder) that causes multiple body system disorders, including neuropathy, organ overgrowth, glandular problems, and skin changes. Mayo Clinic: Information About POEMS Syndrome Excellent, easy to understand information on the disorder, from the Hematology Division, Department of Internal Medicine, Mayo Clinic Rochester (U.S.). NORD: POEMS Syndrome Medical information (technical) on the disorder. Tufts: POEMS Syndrome Listing of medical journal articles related to POEMS syndrome, from Tufts University Neurology (U.S.). Topic Index Email to a Friend Our Story Be a Guide ... New York Times Company Hurricane Katrina About's Hurricane Blogs NY Times Coverage Where to Donate Exclusive: One Family's Story ... How to Explain to Kids Related Topics Multiple Sclerosis Parenting Special Needs Sleep Disorders Headlines Cystic Fibrosis Foundation helps Hurricane Katrina victims Robert J. Beall, Ph.D, President and CEO of the Cystic...

16. Immune Demyelinating PN MAG antibody associated neuropathy Osteosclerotic Myeloma Other demyelinating neuropathies poems syndrome Sulfatide antibody associated http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

17. Entrez PubMed The poems syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy,M protein, and http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

18. POEMS Syndrome Definitions And Long-term Outcome Dispenzieri poems syndrome definitions and longterm outcome Angela Dispenzieri, Robert A. Kyle, Martha Q. Lacy, S. Vincent Rajkumar http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Entrez PubMed The poems syndrome (coined to refer to polyneuropathy, organomegaly, We conclude that the median survival of patients with poems syndrome is 165 months, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

20. Pulmonary Manifestations Of POEMS Syndrome Case Report And Pulmonary Manifestations of poems syndrome* http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

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