61. Special Coagulation Lab capabilities for congenital and acquired bleeding disorders, hyper coagulable evaluations, platelet disorders, and autoimmune coagulation disorders. http://pathology.jhu.edu/N/n.web?EP=N&URL=/MCGI/SEND^WEBUTLTY(10291)

62. Hemic And Lymphatic Diseases Syndrome Blood Coagulation Disorders - Blood platelet disorders - Blue Myeloproliferative Disorders - Neutropenia - Paraproteinemias - Platelet http://www.mic.ki.se/Diseases/C15.html

search search staff sitemap ABOUT KAROLINSKA INSTITUTET ... print this page Diseases and Disorders Links pertaining to Hemic and Lymphatic Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Afibrinogenemia Afibrinogenemia Afibrinogenemia Anemia ... von Willebrand Disease Hemic and Lymphatic Diseases BloodBook .com Human Blood [D O'Neil] - Palomar College (US) Normal Blood - HMDS (UK) Cells of the Blood [clickable map] - University of Leicester (UK) A Demo module Montandon et al. ] from HemoSurf/IMC About Erythrocytes , and Leukocytes - Encyclopedia.com About some Hematological Laboratory Tests - ASCLS An Educational Presentation of Basic Hematology - Puget Sound Blood C.(US) Haem.net [laboratory hematology] HemoSurf , an interactive hematology atlas [Woermann et al.] Morphological Cell Atlas [registration required, no charge] - CellaVision AB Some Blood Chemistry Definitions - Carbon Based Corp.

63. MeSH-D Terms Associated To MeSH-C Term Blood Platelet Disorders MeSHD terms associated to MeSH-C term Blood platelet disorders, G2D Home of the association of the corresponding term to Blood platelet disorders. http://www.bork.embl-heidelberg.de/g2d/c2d.pl?Blood_Platelet_Disorders:unknown

64. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Blood_Disorders/Pl bleeding caused by qualitative platelet disorders and many more topics. Platelet Disorder Support Association Information and support for those with http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Blood_Disor

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Blood Disorders : Platelet Subtopics Search Google: Platelet News Books Links ... Trial At Jefferson Shows New Drug May Help Cancer Patients Who Need Stem Cell Transplants (September 8, 2005) full story Medication Reduces Risk Of Heart Attack And Cardiovascular Death Before And After Angioplasty (September 4, 2005) JAMA full story Cocoa Is The New Red Wine: Shows Benefits For Coronary Heart Disease (August 12, 2005) full story UNC Scientists Discover New Role For Protein As Fundamental Inhibitor Of Cell Movement (August 10, 2005) full story Anti-tumor Activity Also Plays A Critical Role During Eye Development In The Embryo (August 2, 2005) full story Gene Variants Predict Bleeding After Heart Surgery (May 4, 2005) full story OHSU Study Finds Ginkgo Beneficial For MS Symptoms (April 28, 2005) full story (April 11, 2005) full story [ More news about Platelet Amazon.com's Price: Prices subject to change. Dental And Craniofacial Applications Of Platelet-Rich Plasma by: Robert E. Marx

65. The Laboratory Diagnosis Of Platelet Disorders platelet disorders can be associated with varying platelet appearances. platelet disorders may be divided into 3 major categories platelet dysfunction http://arpa.allenpress.com/arpaonline/?request=get-document&doi=10.1043/0003-998

66. RFA-HL-05-020: Proteomic Studies Of Platelet Functions It is also difficult to diagnose platelet disorders that increase the risk of As a result, most of the platelet disorders have remained qualitative. http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-05-020.html

Part I Overview Information Department of Health and Human Services Participating Organizations National Institutes of Health (NIH), ( http://www.nih.gov Components of Participating Organizations National Heart, Lung, and Blood Institute (NHLBI), ( http://www.nhlbi.nih.gov Title: Proteomic Studies of Platelet Functions Announcement Type New Request For Applications (RFA) Number: RFA-HL-05-020 Catalog of Federal Domestic Assistance Number(s) Key Dates Release Date: July 8, 2005 Letters of Intent Receipt Date(s): December 12, 2005 Application Receipt Dates(s): January 12, 2006 Peer Review Date(s): June/July, 2006 Council Review Date(s): September 2006 Earliest Anticipated Start Date: September 2006 Additional Information To Be Available Date (Url Activation Date): Not applicable Expiration Date: January 13, 2006 Due Dates for E.O. 12372 Not Applicable Additional Overview Content Executive Summary The National Heart, Lung, and Blood Institute (NHLBI) plans to support collaborative research on the application of proteomic tools to identify disorders of human platelet function. Support is intended for the adaptation and application of existing technology to study blood platelets and not for the development of new proteomic technology. We anticipate that such research will lead to more quantitative definitions of platelet disorders. The total amount to be awarded is $2.2 million over two years.

67. HighWire -- Browse Journals - Blood Platelet Disorders Browse Journals publishing on Blood platelet disorders, (return to Topic List page) Platelet Storage Pool Deficiency Thrombocytosis http://highwire.stanford.edu/lists/topic_dir/608683/608684/613947/613948/614082/

ANNOUNCEMENT: CHECK OUT THE PREVIEW RELEASE OF OUR NEW WEB SITE! My Favorite Journals ( HW-hosted journals HW-hosted Medline Author: Keyword(s): Year: Vol: Page: Home Adv. Search For Institutions For Publishers ... Sign in or register for access to all HighWire Press customization features Browse Journals publishing on Blood Platelet Disorders: (return to Topic List page) Blood Platelet Disorders Bernard-Soulier Syndrome Thrombocytopenia Platelet Storage Pool Deficiency Thrombocytosis ... Hematologic Diseases Blood Platelet Disorders Home Adv. Search For Institutions For Publishers ... partners/suppliers

68. Entrez PubMed The Quebec platelet disorder (QPD) is an autosomal dominant platelet disorder Blood platelet disorders/enzymology*; Blood platelet disorders/genetics http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

69. Entrez PubMed and for coverage of surgical procedures in patients with platelet disorders. Cases include seven patients with congenital platelet disorders Glanzmann http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2

70. Guam Medical Libraries Digital Libraries Program Chapter 135 Acquired Disorders of Platelet Function Access document Blood platelet disorders (MeSH browse) List of documents. Clinical Trials http://guam-dl.slis.ua.edu/clinical/hematology/bleedingdisorders/plateletdisorde

Clinical Resources by Topic: Hematology Acquired Platelet Dysfunction Clinical Resources Emergency Pediatrics Geriatrics Pathology ... Miscellaneous Resources See also: General Hematology Clinical Resources Acquired Platelet Dysfunction Patient/Family Resources Hoffman: Hematology: Basic Principles and Practice 4th Ed.-2005 (MD Consult): Table of contents Medical Library subscription INFO Part VIII - Hemostasis and Thrombosis: Access document Chapter 105 - Megakaryocyte and Platelet Structure: Access document Introduction: Access document Megakaryocyte Development: Access document Platelet Formation: Access document Platelets in Circulation: Access document References: Access document Chapter 106 - The Molecular Basis for Platelet Function: Access document Introduction: Access document Molecular Basis of Platelet Adhesion: Access document Platelet Secretion: Access document Molecular Basis of Platelet Aggregation: Access document Acknowledgments: Access document References: Access document References: Access document Chapter 107 - The Molecular Basis of Platelet Activation: Access document Introduction: Access document Overcoming Local Barriers to Platelet Activation: Access document Formation of a Stable Platelet Plug: Access document Conclusion: Access document References: Access document References: Access document Chapter 112 - Clinical Evaluation of Hemorrhagic Disorders: The Bleeding History and Differential Diagnosis of Purpura: Access document Introduction: Access document The Bleeding History: Access document Differential Diagnosis of Hemorrhagic Dermatologic Lesions:

71. Platelet Disorders - General Practice Notebook platelet disorders. The formation of the initial platelet plug is an important component platelet disorders that may interfere with this mechanism are http://www.gpnotebook.co.uk/cache/-1389035490.htm

platelet disorders The formation of the initial platelet plug is an important component of normal haemostasis. Platelet disorders that may interfere with this mechanism are: too few platelets - thrombocytopaenia abnormal platelet function - thrombocytopathy Thrombocytopaenia accounts for the majority of cases. Click here for more information...

72. Studies Of A Second Family With The Quebec Platelet Disorder: Evidence That The CONGENITAL platelet disorders are rare but important causes of abnormal An inherited platelet disorder was suspected, because similar laboratory http://www.bloodjournal.org/cgi/content/full/89/4/1243

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Rights and Permissions PubMed PubMed Citation Articles by Hayward, C. P.M. Articles by Rivard, G. E. Related Collections Hemostasis, Thrombosis, and Vascular Biology Blood , Vol. 89 No. 4 (February 15), 1997: pp. 1243-1253 Studies of a Second Family With the Quebec Platelet Disorder: Evidence That the Degradation of the -Granule Membrane and Its Soluble Contents Are Not Secondary to a Defect in Targeting Proteins to -Granules By Catherine P.M. Hayward Elisabeth M. Cramer William H. Kane Shilun Zheng Madeleine Bouchard and Georges E. Rivard ABSTRACT Abstract Introduction Methods Results Discussion References We recently described a Quebec family with an autosomal dominant bleeding disorder characterized by mildly reduced-low normal platelet counts, an epinephrine aggregation defect, multimerin deficiency, and proteolytic degradation of several, soluble -granular proteins. Similar clinical features led us to investigate a second family with an unexplained, autosomal dominant bleeding disorder. The affected individuals had reduced to normal platelet counts, absent platelet aggregation with epinephrine, and multimerin deficiency. Their platelet

73. The Organization Of Microtubules And Microtubule Coils In Giant Platelet Disorde Some of the cells from patients with giant platelet disorders are also diskshaped, but the majority of their huge platelets are spherical. http://ajp.amjpathol.org/cgi/content/abstract/116/3/514

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS This Article Order Full text via Infotrieve Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager ... Cited by other online articles PubMed PubMed Citation Articles by White, J. G. Articles by Sauk, J. J. REGULAR ARTICLES The organization of microtubules and microtubule coils in giant platelet disorders JG White and JJ Sauk Normal human platelets are characteristically discoid in shape. The lentiform appearance is supported by a circumferential band of microtubules lying just under the cell membrane along its greatest circumference. Some of the cells from patients with giant platelet disorders are also disk-shaped, but the majority of their huge platelets are spherical. In the present study platelets from patients with the Gray platelet syndrome (GPS), May-Hegglin anomaly (MHA), and Epstein's syndrome (ES) were examined in thin sections and negatively stained whole mounts, and by indirect immunofluorescence with a monoclonal antibody to tubulin for determination of the organization of their microtubule systems. Many GPS platelets and

74. NORD - National Organization For Rare Disorders, Inc. A study of platelet disorders is being conducted at the National Institutes of Gray platelet syndrome is a rare bleeding disorder that causes excessive http://www.rarediseases.org/research/clinicaltrials

Database Subscriptions Many libraries, schools, universities, and hospitals subscribe to NORD's Rare Disease Database for unlimited access to reports on more than 1,150 diseases. Index of Rare Diseases This is the list of diseases currently covered in the Rare Disease Database. Rare Disease Database Search this database for reports on more than 1,150 diseases. View sample report Index of Organizations This is the list of organizations in NORD's Organizational Database. Organizational Database Read about more than 2,000 patient organizations and other sources of help. NORD's Washington Office Read about events on Capitol Hill, funding for rare-disease research, and other topics of interest from NORD's office in Washington, DC. Research NORD posts information on this page about current studies for which participants are being recruited. NORD does not promote, endorse, or encourage participation in any specific medical research. We post this page for informational purposes only, and we encourage individuals considering participating in any research project to discuss the matter with their physicians. Research Underway Cronkhite-Canada Syndrome Cronkhite-Canada syndrome (CCS) is a very rare disease with symptoms that include loss of taste, intestinal polyps, hair loss, and nail growth problems. It is difficult to treat because of malabsorption that accompanies the polyps. CCS occurs primarily in older people (average age 59) and it is not believed to have a genetic component. There have been fewer than 400 cases reported in the past 50 years, primarily in Japan but also in the U.S. and other countries.

75. Disease Category Listing (121): Platelet Disorders CenterWatch Listing of Clinical Research Trials for platelet disorders. http://www.centerwatch.com/studies/cat121.htm

Clinical Trials: Platelet Disorders There are no studies currently listed in this category on the CenterWatch web site. Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: September 8, 2005 at 3:11:19 PM Patient Resources: [ Trial Listing Notification Services Drug Directories About Clinical Research ... Patient Bookstore Professional Resources: [ Research Center Profiles Industry Provider Profiles Industry News Professional Resources ... Professional Bookstore General: [ Search Site Map Your Privacy CW World ... Home This site was developed in association with Illumina Interactive , Boston, MA

76. Preface platelet disorders include a case of platelet satellitism as well as thrombocytopenias and thrombocythemia. Blood parasites include babesiosis, filariosis, http://www.ivis.org/advances/Camacho/camacho/chapter_frm.asp?LA=1

77. OHSU Division Of Hematology & Medical Oncology An article by Thomas G. DeLoughery, Associate Professor of Medicine. platelet transfusion therapy and dysfunctional platelets are discussed. http://www.ohsu.edu/som-hemonc/handouts/deloughery/bleed.shtml

Contact Information: 3181 SW Sam Jackson Park Rd Portland, OR 97239-3098 Phone: (503) 494-6594 Email: hemonc@ohsu.edu Find a Doctor FAQ Sheet Construction Updates About our Division Clinical Trials Our Faculty About our Clinic ... Prostate Cancer Program Healthcare Professionals Physician Career Opportunities Fellowship Program Faculty Publications and Research Interests Dr. Thomas Deloughery's Famous Handouts ... Dr. Skach's Lab General Information Hem Onc in the News Helpful Links Lance Armstrong Foundation OHSU Hem Onc Wears Yellow News Upcoming Events ASH 2004 Faculty Spotlight Craig Nichols, M.D. Division Chief "The disease of cancer will be banished from life by calm, unhurrying, persistent men and women, working with every shiver of feeling controlled and suppressed in hospitals and laboratories, and the motive that will conquer cancer will not be pity or horror; it will be curiosity to know how and why." H.G. Wells, 1901

78. The HELLP Syndrome Society International network for persons affected by the combined disorders of hemolysis, elevated liver enzymes and low platelet count. http://hometown.aol.com/hellp1995/index.html

htmlAdWH('93212816', '728', '90'); Main The HELLP Syndrome Society, Inc. site has moved. We'll now go to: http://www.hellpsyndrome.org

79. Types Of Platelet Function Disorder Hereditary platelet function disorders can be divided into five groups Three platelet function disorders involve platelet secretion.1) In Alpha Granule http://www.hemophilia.ca/en/2.4.4.php

Platelet Function Disorders Types of Platelet Function Disorder Platelet Function Disorders Types of Platelet Function Disorder Hereditary Platelet function disorders Disorders of platelet adhesion Disorders of platelet aggregation Disorders of platelet secretion ... Acquired Platelet function disorders Hereditary Platelet function disorders Hereditary platelet function disorders can be divided into five groups depending on the type of abnormality. Disorders of platelet adhesion This rare disorder is called Bernard-Soulier Syndrome. It is caused by a deficiency on the surface of the platelet in an area called Glycoprotein Ib/IX. As a result, platelets fail to stick and clump together at the site of the injury. (See Figure 1, stage 3.) The disorder is often first noticed during childhood. Children have frequent bruises, nose bleeds and bleeding in the mouth and gums. Some may experience gastrointestinal bleeding (bleeding in the gut). Women may experience heavy menstrual bleeding, or their menstruations (periods) last longer than normal. This is called menorrhagia. Blood tests show: a prolonged bleeding time (bleeding time is a measure of the time it takes for a simple cut to stop bleeding) a low platelet count (this means that there are fewer platelets than normal) that the platelets appear larger than normal when seen through a microscope that the platelets do not clump together in response to ristocetin.

80. Low Platelets In the disorders described below, the immune system destroys platelets in the Cyclical thrombocytopenia is a rare platelet disorder characterized by http://www.itppeople.com/lowplate.htm

SEARCH About ITP Treatments Stories ... Advocacy Help Us Help You Contribute via the United Way, CFC, car donations, matching gifts... Low Platelet Disorders (Adapted by the PDSA Staff from A Low Platelet Count Must Be ITP, Right?, by Jonathan G. Drachman M.D, Puget Sound Blood Center. The article appeared in The Platelet News, vol.4, no 4, winter 2002/2003, see www.pdsa.org/newsletter.htm A low platelet count is frequently assumed to represent ITP (immune thrombocytopenic purpura). However there are many other possible causes of thrombocytopenia, with clinical severity ranging from trivial to life threatening. ITP is a diagnosis of exclusion. This means that only after all other possible causes of low platelets have been ruled out, can a diagnosis of ITP be settled. This makes it important to know or at least be aware of the other common causes of low platelets that may be mistaken for or misdiagnosed as ITP. These other causes are either platelet production problems centered in the bone marrow or platelet destruction problems centered in the liver or spleen. Some low platelet conditions are characterized by both a low rate of production and a high rate of platelet destruction. The most common conditions or defects responsible for low platelets are listed below in the following categories: I. Platelet Production Problems

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