41. CCHS Clinical Digital Library platelet disorders Patient/Family Resources by SubTopic. Acquired Platelet Dysfunction Myeloproliferative Disorders Thrombocytopenia http://cchs-dl.slis.ua.edu/patientinfo/hematology/bleedingdisorders/plateletdiso

Patient/Family Resources by Topic: Hematology Platelet Disorders Patient/Family Resources See also: Platelet Disorders Clinical Resources General Hematology Patient/Family Resources Platelet Disorders Patient/Family Resources by Sub-Topic: Acquired Platelet Dysfunction Myeloproliferative Disorders Thrombocytopenia von Willebrand Disease ... College of Community Health Sciences The University of Alabama Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

42. Platelets Platelets Thrombotic Disorders and antithrombotic therapy Vascular Biology Inherited and acquired platelet disorders http://www.blackwellpublishing.com/febsabstracts2004/subjectIndex.asp?subject=5&

43. Blood Platelet Disorders Topic - Unified Search Environment Disorders caused by abnormalities in platelet count or function. Synonyms and Source Vocabularies Blood platelet disorders MSH/MH/D001791 LCH/PT/U000618 http://www.use.hcn.com.au/portals/shared/subject.`Blood Platelet Disorders`/home

Blood Platelet Disorders Topic Tree Definition: Disorders caused by abnormalities in platelet count or function. Synonyms and Source Vocabularies: Blood Platelet Disorders Thrombocytopathy platelet disorder thrombocyte disorders Hematologic Diseases Anemia Blood Coagulation Disorders Blood Group Incompatibility Blood Platelet Disorders Bernard-Soulier Syndrome Platelet Storage Pool Deficiency Thrombasthenia Thrombocytopenia ... Thrombophilia

44. Neonatal Platelet Disorders Penn State Children’s Hospital NICU team involves practitioners who care for premature and critically ill infants. http://www.hmc.psu.edu/nicu/services/plateletdisorders.htm

45. July 2000 - Platelet Closure Times Closure times are indicated when a disorder of platelet function is suspected by a Suspected von Willebrand’s disease, inherited platelet disorders and http://www.itxm.org/TMU2000/tmu7-2000.htm

July 2000 Closure Time Platelet Function Screening Andrea Cortese Hassett, Ph.D. and Franklin A. Bontempo, M.D. BACKGROUND Platelet dysfunction may be acquired, inherited, or induced by platelet inhibiting agents. It is clinically important to assess platelet function as a potential cause of a bleeding diathesis, especially in critically ill patients who may develop life-threatening hemorrhages. The most common causes of platelet dysfunction are related to uremia, liver disease, von Willebrand’s disease (vWD) and exposure to agents such as acetyl salicylic acid (ASA, aspirin). Current methods to assess platelet function include bleeding time (BT), aggregation studies and whole blood in vitro test systems such as the closure time (CT). CLOSURE TIME TESTING Closure times are performed on a PFA-100, an instrument and test cartridge system in which the process of platelet adhesion and aggregation following a vascular injury is simulated in vitro This system allows for rapid evaluation of platelet function on samples of anticoagulated whole blood.

46. Chasing After The Causes Of Platelet Disorders - College Of American Pathologist Giant platelet disorders also have characteristic electron microscopic findings. In thrombocytopenic platelet disorders with normal platelet morphology http://www.cap.org/apps/docs/cap_today/feature_stories/platelet_disorders_featur

College of American Pathologists Home Request Account Contact Us Terms and Conditions ... Feedback Search Chasing after the causes of platelet disorders June 2002 Feature Story George Corcoran, MD, and Kandice Kottke-Marchant, MD, PhD The following article was adapted from the Multiple etiologies exist for platelet-derived bleeding disorders. The laboratory evaluation of these disorders can range from simple to complex and should initially include a thorough evaluation of the patient's medical history, concentrating on personal and familial bleeding disorders and current medications. With this as a starting point, the algorithms presented here may be helpful in elucidating the underlying etiology for platelet-derived bleeding. Role of platelets in hemostasis Platelets are small (2 µm-diameter), non-nucleated blood cells produced in the bone marrow from megakaryocytes. They are rapidly activated by blood vessel injury and are a crucial component of the primary hemostatic response. In their unactivated state, platelets are roughly discoid in shape and contain cytoplasmic organelles, cytoskeletal elements, invaginating open-canalicular membrane systems, and platelet-specific granules called alpha and dense granules. Platelets have numerous intrinsic glycoproteins attached to the outer surface of their plasma membrane that are receptors for such ligands as fibrinogen, collagen, thrombin, and thrombospondin to von Willebrand factor and fibronectin.

47. Platelet Disorders - Talk Medical Expert Complications advice on platelet disorders. http://www.talkmedical.com/parenting-pregnancy/10/Platelet-Disorders

Home Medications Medical Dictionary Talk Medical ... Complications Newsletter Subscribe to the free monthly health digest. Relevant health articles just for you. Tell a friend Platelet Disorders Platelets are blood cells that play a crucial role in blood clotting. If a fetus does not have enough platelets when it is born, it is at risk of bleeding within its organs or its skull. The condition of having low blood platelet levels is known as thrombocytopenia and affects 1/5000 births. Sometimes mothers may produce antibodies that kill fetal platelets if they too have a platelet disease. If a fetus is suspected of having a low platelet count, it may be delivered by cesarean section and treated with platelet transfusions and gammaglobulin. Print this page About Talk Medical Help Contact Us ... Terms and Conditions

48. Platelet : Blood Disorders : Disorders And Diseases : Health And Fitness Platelet Disorder Support Association popular. http//www.pdsa.org for those with immune thrombocytopenic purpura and other low platelet disorders http://www.internet-web-directory.com/Health_and_Fitness/Disorders_and_Diseases/

Skip to Content Login/Register Web Directory by Internet-Web-Directory.com Web Directory Home ... Link Notify Search the entire directory only this category Advanced Search Web Directory Health and Fitness Disorders and Diseases ... Blood Disorders Platelet Platelet Subscribe Links Essential Thrombocythemia popular http://www.beverlyblevins.com Information on diagnosis, treatment, and management of rare bone marrow disease affecting platelets More Details Review It Rate It Bookmark It ... Glanzmann Thrombasthenia popular http://WWW.GLANZMANNS.ORG Supporting those affected by GT and reseachers. Message board, contacts and related information on the condition. More Details Review It Rate It Bookmark It ... Platelet Disorder Support Association popular http://www.pdsa.org Information and support for those with immune thrombocytopenic purpura and other low platelet disorders More Details Review It Rate It Bookmark It Sponsor Links Love Romance Dating Gift Ideas at Gifts-Shop.com Internet-Web-Directory.com

49. From The Grand Rounds Archive At Baylor platelet disorders are characterized by petechiae, purpura, mucosal membrane Examples of congenital platelet disorders include Thrombocytopenia absent http://www.bcm.edu/oto/grand/11394.html

Grand Rounds Archives The information contained within the Grand Rounds Archive is intended for use by doctors and other health care professionals. These documents were prepared by resident physicians for presentation and discussion at a conference held at The Baylor College of Medicine in Houston, Texas. No guarantees are made with respect to accuracy or timeliness of this material. This material should not be used as a basis for treatment decisions, and is not a substitute for professional consultation and/or peer-reviewed medical literature. BLEEDING DISORDERS IN PEDIATRIC OTOLARYNGOLOGY November 3, 1994 Warren E. Morgan, M.D. Bleeding disorders may complicate many routine otolaryngology procedures. This may result from technical errors, but bleeding associated with defects in the coagulation system may be difficult to control. All otolaryngologists should be aware of common bleeding disorders and their treatment. Normal coagulation may be divided into three phases: vascular response, platelet activation, and the coagulation cascade. The initial vascular response of vasoconstriction occurs immediately after the injury. Platelet adherence occurs in response to collagen exposure by endothelial damage. Further platelet adhesion is mediated through specific platelet receptors and mediators creating an unstable hemostatic plug. Coincident with the platelet activation, the coagulation cascade is initiated by the release of tissue thromboplastin and contact-activating factors. The coagulation cascade forms a fibrin matrix that reinforces the platelet plug.

50. Hemophilia Galaxy | A Detailed Guide To Bleeding Disorders platelet disorders. Platelets are small proteincontaining cellular In platelet disorders, bleeding generally occurs immediately following injury, http://www.hemophiliagalaxy.com/patients/about/rarebleed/guide.html

Home Encyclopedia Contact Us About Hemophilia ... rare bleeding disorders A Detailed Guide to Bleeding Disorders A Detailed Guide to Bleeding Disorders Below is a detailed look at some of the many bleeding disorders affecting people worldwide. You'll learn about the most common inherited bleeding disorder (hint: it's not hemophilia), and discover the difference between factor deficiencies and platelet disorders. For a brief overview, see A Quick Comparison of Selected Bleeding Disorders In general, bleeding disorders can be divided into two major categories: Factor deficiencies. Clotting factors are specialized proteins circulating in the blood. These factors work together in a chain reaction to form clots. If even one of these factors is missing or deficient, clotting is impaired. Hemophilia is perhaps the best-known factor deficiency. Specifically, a deficiency of Factor VIII results in hemophilia A, while a deficiency of Factor IX leads to hemophilia B. There are many other factor deficiencies, however, as you can see from the summaries below. To learn more, click Factor Deficiencies Platelet disorders.

51. Treated Diseases Disease. platelet disorders. Associated Doctors. Spero Cataland, MD. Assistant Professor Clinical of Internal Medicine. « return to list http://oncology.osu.edu/11248.cfm?uaction=diseaseDets&disease_id=30

52. Disease - Acquired Platelet Function Defect - Hartford, Connecticut Acquired qualitative platelet disorders; Acquired disorders of platelet function Acquired platelet function disorders are disorders of inappropriate http://www.saintfranciscare.com/1781.cfm

@import url(main.css); About Us Health Information Health Focus Todays Breast Health News ... Ways To Help Adam Article Manager Back Back to main Health Information page Disease - Acquired platelet function defect Blood clot formation Blood clots Definition: Acquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Alternative Names: Acquired qualitative platelet disorders; Acquired disorders of platelet function Causes And Risk: Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present.

53. Blood Disorders Article | Physical Disorders & Oral Health | Colgate® Oral Ca Two of the most common platelet disorders are idiopathic thrombocytopenic People with platelet disorders tend to have more cavities, more teeth that http://www.colgate.com/app/Colgate/US/OC/Information/OralHealthBasics/MedCondOra

Colgate Worldwide Oral Care Personal Care Household Care ... Article Index Oral Health Basics Oral Health Basics Good Oral Hygiene Common Concerns Emergencies/Injuries ... Orthodontics Blood Disorders Neutropenia Oral Effects People with neutropenia have low levels of white-blood cells called neutrophils, which provide the first line of defense against bacterial infections. Neutropenia most often results from medications that inhibit the production or maturation of neutrophils in the bone marrow. If you have neutropenia, you are more susceptible to infections, including bacterial infections in your mouth. However, you may have no or few signs of infection because the neutrophils that cause redness and inflammation are not available to do so. This means the classic signs of infection are less obvious to your dentist. It also means that infections such as periodontal (gum) disease and oral ulceration can progress rapidly. People with severe neutropenia can have deep ulcers in their mouths. They may not be accompanied by inflammation, but often are painful. At the Dentist Because people with neutropenia are more susceptible to bacterial infections, they sometimes are given antibiotics before major dental treatment. Whether your dentist decides to do this depends on the severity of the neutropenia. A normal neutrophil count is between 3,000 and 6,000 cells. Generally, if your neutrophil count is less than 1,000, you will need antibiotics before dental treatment.

54. Rehabilitation Oncology: Platelet Disorders And Their Implications On Physical T Full text of the article, platelet disorders and their implications on physical therapy intervention from Rehabilitation Oncology, a publication in the http://www.findarticles.com/p/articles/mi_qa3946/is_200101/ai_n8951914

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Rehabilitation Oncology Content provided in partnership with 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Platelet disorders and their implications on physical therapy intervention Rehabilitation Oncology by Zavadsky, Aaron Joseph Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. INTRODUCTION Today, oncology patients are subjected to a myriad of treatments to both prolong and save lives. Some of these procedures include bone marrow transplants, chemotherapy, and radiation. Unfortunately, potentially serious side effects may arise from these procedures. One such life-threatening complication is a decrease in the number of platelets (thrombocytopenia). Platelets are cells in whole blood that help the blood to clot. If one's platelet levels are low, he/she faces the risk of abnormal bleeding. This bleeding may occur for 2 main reasons: (1) the patient's bone marrow cannot produce enough platelets, or (2) their platelets have been destroyed by disease.1

55. Children's Research Institute David Wilcox Blood Disorders Research Hematology R Wilcox, DA; White II, GC Gene therapy for platelet disorders studies with Glanzmann s thrombasthenia. Journal of Thrombosis and Haemostasis. http://www.chw.org/display/PPF/DocID/11376/router.asp

About us Investigators Research volunteers Investigator resources ... Investigator bios : Wilcox, David E-mail this page Print this page David A. Wilcox, PhD Hematology/Oncology Education National Advisory Committees and/or Activities: Scientific reviewer, Thrombosis and Haemostasis, Journal of Thrombosis and Haemostasis, Blood, and Biology of Blood and Marrow Transplantation ; Ad hoc reviewer, National Institutes for Health Study Section for Hemostasis and Thrombosis. Professional and Honorary Societies: American Heart Association, Scientific Council member; American Society of Gene Therapy, American Society of Hematology, International Society of Thrombosis and Haemostasis. Invited presentations: Gordon Research Conference on Hemostasis, Plymouth, N.H., 2000, Use of a IIb Promoter in Retroviral Constructs BMS Seminar/Goodwin Lecturer, Auburn University, Alabama, 2002, Targeting Gene Therapy for Inherited Hematological Disorders and The Molecular Basis for Gene Therapy Using Hematopoietic Stem Cells; 45th Annual Meeting of the American Society of Hematology, San Diego, 2003

56. Thrombopoietin, Modes Of Action And Role In Platelet Disorders Thrombopoietin modes of action, role in platelet disorders new drug Role of Tpo in platelet disorders. Disorders with thrombocytopenia http://www.slz.nl/hora/literatu/pages/1998/tpo.htm

Albert E.G.Kr. von dem Borne , Leendert Porcelijn , Claudia Folman , Sonja van den Oudenrijn , Gabor E Linthorst , C. Ellen van der Schoot , Masja de Haas 1 Department of Hematology, Division of Internal Medicine, Academic Medical Center, 2. Department of Hematology, Division of Medical Oncology, Anthonie van Leeuwenhoek Hospital/The Netherlands Cancer Institute, and 3. Department of Experimental Immunohematology, Central Laboratory of the Netherlands Red Cross Blood Transfusion Center Correspondence: Albert E.G.Kr. von dem Borne, Department of Hematology, Division of Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam; E-mail borne@amc.uva.nl Table of Contents Introduction Structural Information Thrombopoietin Tpo receptor (Tpo-R) ... Reference List Introduction Thrombopoietin (Tpo) is a haematopoietic growth factor that stimulates the development of megakaryocyte precursors, megakaryocytes and platelets. The existence of such a factor was already suggested in 1958 (Kelemen et al , 1958) and demonstrated in the early sixties by studies in rats (Odell et al , 1961). However, attempts to obtain thrombopoietin were unsuccessful in the years thereafter.

57. Blood Disorders In Patients With SLE In summary, blood disorders in lupus include anemia, platelet disorders, Commonly encountered platelet disorders include ITP and antiphospholipid http://www.lupusmn.org/Education/Articles/BloodDisordersinPatientswithSLE.htm

Donate Volunteer Press Lupus Foundation of Minnesota The Atrium Suite 135 2626 East 82nd Street Bloomington, MN 55425 Phone Number Email us Proud member of: Support Services Research Education Events About Us Education Back to Education Page Back to Lupus Articles Listing Blood Disorders in Patients with Lupus Patients with systemic lupus erythematosus may develop disorders of the blood components, also called hematologic disorders. The blood components which can be affected in lupus include red blood cells, platelets and white blood cells. In addition, patients with lupus may develop antibodies which predispose them to easy blood clotting. In this article I will discuss the various causes of anemia, platelet disorders, white blood cell abnormalities, and clotting abnormalities seen in lupus. Anemia Anemia is defined as abnormally low hemoglobin concentration in blood. Red blood cells contain hemoglobin which contains iron and is responsible for carrying oxygen to the tissues of the body. Some symptoms of anemia include fatigue, weakness, palpitations and shortness of breath. Symptoms severity depends on the severity of the anemia. There are many different causes of anemia.

58. Faculty-McMaster Department Of Pathology And Molecular Medicine Hayward CPM. Inherited platelet disorders. Current Opin Hematol 2003; 10 362368. Veljkovic DK, Cramer EM, Fichelson S, Massé JM, Hayward CPM. http://www.fhs.mcmaster.ca/path/directory/fac/hayward.htm

Directory Faculty Administration Technicians Post-Doctoral Fellows Catherine P.M. Hayward MD, PhD, FRCP(C) Professor Pathology and Molecular Medicine Associate Member, Medicine Director, McMaster University Clinician Investigator Program Head, Coagulation, Hamilton Regional Laboratory Medicine Former Director, Adult Hematology Residency Program Member, Faculty of Health Sciences Research Council 2N31 Health Sciences Centre McMaster University 905-521-2100 ext. 73373 905-525-9140 ext. 22157 or 22256 (Lab) haywrdc@mcmaster.ca Currently accepting Graduate Students Currently accepting Post Doctoral Fellows Education and Professional Standing PhD, (Gold Medalist) Medical Sciences, McMaster University, 1995 MD, University of Western Ontario, 1984

59. Bleeding Disorders Program Platelets Physiology and Diagnosis of platelet disorders. Dr. Thomas Ortel. 1415 1445 Inherited Disorders of Platelet Function KFSH RC Experience http://www.kfshrc.edu.sa/symposia/html/bleeding_disorders_program.html

Symposium "First Saudi International Symposium on Bleeding Disorders" 21-23 February 2004 / 01-03 Muharram 1425 SATURDAY, 21 FEBRUARY 2004/ 01 Muharram 1425 Registration Reading of the Holy Quran Opening Ceremony Dr. Abdulrahman Al Nuaim Dr. Khalid Al Shaibani Dr. Ahmed Al Shaikh Dr. Abdullah Al Amro Dr. Hassan El Solh Dr. Fouad Al Dayel SESSION I: History of Hemophilia at KFSHRC Dr. Abdulrahman Al Musa History of Hemophilia: Arab and Islamic Prespective Dr. Mahasen Al Saleh The World Federation of Hemophilia (WFH) Dr. Assad Haffar The National Hemophilia Program Dr. Hazzaa Al-Zahrani Hemostasis: Structure and Function of Clotting Factors Prof. Abduljaleel Abdulkader Coffee Break SESSION II: HEMOPHILIA- CLINICAL ASPECTS Chairs: Dr. Ibrahim Al Molhem Dr. Reem Al-Sudairy Hemophilia: Clinical Overview Dr. Priti Seth Dr. Steve Kitchen New Trends in the Management of Bleeding Disorders Dr. Galila Zaher Hemophilia Prophylaxis Therapy Dr. Abdulrahman Al Musa SESSION III: COMPLICATIONS OF HEMOPHILIA Chairs: Dr. Fahad Al Othman Dr. Baseam Beiroti

60. CSMLS / SCSLM : Continuing Education/ Éducation Permanete Case Studies Patients with platelet disorders Series One (Advanced) Interested in challenging and unusual platelet disorders? http://www.csmls.org/CE/CE_course_category.cfm?Category=04&&CFID=861598-96

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