21. Qualitative Platelet Disorders Both quantitative and qualitative platelet disorders can predispose an Storage Pool Disorders are a category of qualitative platelet disorders http://www.med.umich.edu/1libr/aha/umqpd.htm

Adult Health Topics All Health Topics Find a UMHS Doctor Search Adult Topics Search All Topics This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. Qualitative Platelet Disorders What are platelets? Platelets are small disc shaped cells that are formed in the bone marrow. Seventy to eighty percent of platelets circulate in the bloodstream while the remainders are stored in the spleen. The average platelet lives about 10 days. Platelets play a crucial role in helping blood to clot. The primary functions of platelets are adhesion, aggregation, activation and secretion (Table I). A defect in any one of these functions will result in an increased tendency to bleed. Table I Platelet Functions Platelet adhesion occurs when there is an injury to a blood vessel. Platelets attach to the lining of the injured blood vessel and begin the first phase of the clotting process.

22. Neonatal Platelet Disorders Neonatal platelet disorders If you do not have Adobe Acrobat Reader installed, you may download a copy here. Neonatal platelet disorders http://neonatal.peds.washington.edu/NICU-WEB/platelets.stm

University of Washington Academic Medical Center Children's Hospital and Regional Medical Center Neonatal Platelet Disorders Authors Created Reviewed Revised This file requires Adobe Acrobat Reader. If you do not have Adobe Acrobat Reader installed, you may download a copy here Neonatal Platelet Disorders Authors About NICU-WEB Authorship Primary Author Thomas Strandjord, M.D. Associate Professor Contributing Authors Christine Gleason, M.D. Professor Alan Hodson, M.D. Professor Craig Jackson, M.D. Professor Dennis Mayock, M.D. Associate Professor Janet Murphy, M.D. Associate Professor Peter Tarczy-Hornoch, M.D. Associate Professor David Woodrum, M.D. Professor Web Mildred Hill EMAIL feedback regarding this document

23. Dr. Koop - Acquired Platelet Function Defect Acquired qualitative platelet disorders; Acquired disorders of platelet function platelet disorders can include inappropriate number of platelets (too http://www.drkoop.com/ency/93/000546.html

Home Health Reference Acquired platelet function defect Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library Inside DrKoop News Archive Animations Health Videos Health Tools ... Newsletters Acquired platelet function defect Injury Disease Nutrition Poison ... Prevention Acquired platelet function defect Definition: Acquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Alternative Names: Acquired qualitative platelet disorders; Acquired disorders of platelet function Causes, incidence, and risk factors: Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present.

24. Guidelines For The Management Of Platelet Disorders Bleeding is unexpected, implies qualitative platelet disorder These disorders may be suspected after abnormal platelet aggregation results http://peir.path.uab.edu/coag/article_223.shtml

Front Page Announcements Contact Us Clinical Conditions ... Test Order Form Search All Categories Front Page Announcements Contact Us Clinical Conditions Guidelines Links Patient Information Test Menu Test Order Form Guidelines Guidelines for the Management of Platelet Disorders Email this article Printer friendly page Platelet Count Thrombocytopenia: The Most Common Cause of Bleeding ... Thrombotic Thrombocytopenic Purpura (TTP) and the vWF-Cleaving Protease (ADAMTS-13) Assay Platelet Count Ranges and Thrombocytopenia /L /L Bleeding is unexpected, implies qualitative platelet disorder /L Bleeding may follow trauma, surgery, or dental extraction /L Spontaneous bleeding may require therapy [top] Thrombocytopenia: the most common cause of bleeding Marrow hypoplasia: chemotherapy, drug sequelae, ethanol Immune-mediated platelet consumption: acute and chronic autoimmune thrombocytopenic purpura, drug-induced immune thrombocytopenia, neonatal alloimmune thrombocytopenia, post-transfusion purpura Non-immune mediated platelet consumption: thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, DIC, HIT, type 2B vWD, etc [top] /L Reactive thrombocytosis: hemorrhage, surgery, iron deficiency anemia, inflammation - normal platelets - no bleeding risk

25. MedlinePlus Medical Encyclopedia: Acquired Platelet Function Defect Acquired qualitative platelet disorders; Acquired disorders of platelet function platelet disorders can involve an inappropriate number (too many or too http://www.nlm.nih.gov/medlineplus/ency/article/000546.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Acquired platelet function defect Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Blood clot formation Blood clots Alternative names Return to top Acquired qualitative platelet disorders; Acquired disorders of platelet function Definition Return to top Acquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Causes, incidence, and risk factors Return to top Platelets are blood cells that are essential for blood clotting. Platelet disorders can involve an inappropriate number (too many or too few) or improper functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital (present at birth) diseases or acquired conditions. Acquired platelet function disorders involve improper platelet function. They develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present.

26. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Blood+Plat ABC of clinical haematology platelet disorders Liesner and Congenital abnormalities can be disorders of platelet production or platelet All serious bleeding due to a platelet disorder needs haematological http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Blood Platelet Disorders

27. Platelet Disorders platelet disorders. Qualitative. Functional disorders (adhesion, aggregation, secretion); Very rare; Only once laboratory testing has eliminated all else do http://www.uq.edu.au/vdu/HDUAnaemiaPlatelet.htm

Virology The Basics Taxonomy Links ... HOME Headlines DNA Down Under New section on RNA interference as a tool to block virus replication. Platelet Disorders Qualitative Functional disorders (adhesion, aggregation, secretion) Very rare Only once laboratory testing has eliminated all else do we settle for this Perform a blood smear from blood without an anticoagulant and look for clumping BT - normal reflects good function Perform platelet aggregation studies Bernard Soulier Syndrome Autosomal recessive, lifelong bleeding disorder Epistaxis, gastrointestinal tract bleeding, menorrhagia, easy bruising and excess bleeding following trauma Lack portions of the platelet membrane (eg GP Ib) which prevents interaction of platelets with vWF and subsequent adhesion to collagen Platelet count is normal to decreased BT is prolonged (relative to the slight decrease in platelets) Platelet aggregation test abnormal / Ristocetin abnormal New look for June 2003 About VDU Contact VDU Last edited: 07-Aug-2005 21:08

28. The Health Library — Blood And Lymphatic Systems platelet disorders. (Jump to Thrombocythemia (Excess Platelets) Thrombocytopenia Thrombocythemia (Excess Platelets). See Bone Marrow Disorders, http://healthlibrary.stanford.edu/resources/internet/bodysystems/blood_platelet.

Diseases and Disorders Use these links to jump directly to your topic of interest Blood and Lymphatic Systems: Blood-Related Cancers: General Information Leukemia (General) Acute Lymphocytic Leukemia (ALL) Acute Myeloid Leukemia (AML) ... Non-Hodgkin's Lymphoma Other Blood Disorders: Anemia Bleeding Disorders Bone Marrow Disorders Methemoglobinemia ... White Blood Cell Disorders Other Lymphatic Disorders: Histiocytosis Lymphedema Spleen Disorders Other Topics: General Blood and Lymphatic System Lymphatic System Anatomy Blood and Lymphatic System Diagnostic Tests Blood Transfusion ... Stem Cell Transplantation (Blood and Marrow) Platelet Disorders (Jump to: Thrombocythemia (Excess Platelets) Thrombocytopenia (Platelet Deficiency Thrombotic Thrombocytopenic Purpura Von Willebrand Disease Thrombocythemia (Excess Platelets) See Bone Marrow Disorders, Myeloproliferative Disorders Thrombocytopenia (Platelet Deficiency) General Information Thrombocytopenia:Merck Manual Low Platelet Disorders:Platelet Disorder Support Association Platelet Disorders and Oral Health:Columbia University School of Dental and Oral Surgery An Update on Diagnosis and Management of Thrombocytopenic Disorders:ASH ... Congenital and Acquired Thrombocytopenia:ASH Heparin-Induced Thrombocytopenia Heparin-Induced Thrombocytopenia:Rare Thrombotic Diseases Consortium Heparin-Induced Thrombocytopenia:Thrombosis Interest Group of Canada Preventing Complications in Heparin-Induced Thrombocytopenia:Postgraduate Medicine Type II Heparin-Induced Thrombocytopenia: New Treatment Options:Cleveland Clinic Idiopathic Thrombocytopenia Purpura (ITP)

29. Bleeding Disorders Platelet Disorder Support Association, Low platelet disorders. This page last modified on December 10, 2004. In the News • Understanding Your Tests • Inside http://www.labtestsonline.org/understanding/conditions/bleeding_disorders-3.html

TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

30. Bleeding Disorders Abnormal result may indicate acquired platelet disorder or von Willebrand’s disease. Platelet Disorder Support Association, Low platelet disorders http://www.labtestsonline.org/understanding/conditions/bleeding_disorders-5.html

TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

31. AllRefer Health - Acquired Platelet Function Defect (Acquired Disorders Of Plate Acquired Platelet Function Defect (Acquired Disorders of Platelet Function, Acquired Qualitative platelet disorders) information center covers causes, http://health.allrefer.com/health/acquired-platelet-function-defect-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Acquired Platelet Function Defect Acquired Platelet Function Defect Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Acquired Disorders of Platelet Function, Acquired Qualitative Platelet Disorders Definition Acquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Blood Clot Formation Blood Clots Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the

32. AllRefer Health - Acquired Platelet Function Defect Pictures & Images (Acquired Acquired Platelet Function Defect (Acquired Disorders of Platelet Function, Acquired Qualitative platelet disorders) pictures and images. http://health.allrefer.com/health/acquired-platelet-function-defect-pictures-ima

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Web health.allrefer.com You are here : AllRefer.com Health Acquired Platelet Function Defect Acquired Platelet Function Defect Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Acquired Disorders of Platelet Function, Acquired Qualitative Platelet Disorders Click on an image thumbnail to view full size Blood Clot Formation Blood clotting normally occurs when there is damage to a blood vessel. Platelets, which come from white blood cell fragments, immediately begin to adhere to the cut edges of the vessel and release chemicals to attract even more platelets. A platelet plug is formed, and the external bleeding stops. Next, small molecules, called clotting factors, cause strands of blood-borne materials, called fibrin, to stick together and seal the inside of the wound. Eventually, the cut blood vessel heals and the blood clot dissolves after a few days.

33. ITP/Platelet Disorders - Children's Hospital Boston ITP/platelet disorders. Down Arrow, Idiopathic (Immune) Thrombocytopenia Return to. Blood Disorders. X. Home Clinical Services Idiopathic (Immune) http://www.childrenshospital.org/clinicalservices/Site1972/mainpageS1972P0.html

or find by letter: A-F G-L M-R S-Z ITP/Platelet Disorders Idiopathic (Immune) Thrombocytopenia Purpura Innovations and Research Second Opinions Meet the Team Contact Us Return to Blood Disorders Home Clinical Services Idiopathic (Immune) Thrombocytopenia Purpura The ITP Program at Children's Hospital Boston provides comprehensive care for children and adolescents with Idiopathic (Immune) Thrombocytopenic Purpura, or ITP. As a world leader in ITP research, the program offers patients access to the latest treatments and clinical trials in the field. The program is staffed by pediatric hematologists who are experts in diagnosing and treating childhood ITP. The ITP Program hosts a unique website, www.itpkids.org , to provide helpful information about the condition and its treatment. Related Topics Idiopathic Thrombocytopenia Purpura Related Topics Idiopathic Thrombocytopenia Purpura Children's Hospital Boston is the primary pediatric teaching hospital of Harvard Medical School Contact Us Privacy Accessibility Give Now Children's Hospital Boston 300 Longwood Avenue Boston MA 02115

34. ITP/Platelet Disorders - Children's Hospital Boston ITP/platelet disorders. Idiopathic (Immune) Thrombocytopenia Purpura Return to. Blood Disorders. X. Home Clinical Services Idiopathic (Immune) http://www.childrenshospital.org/clinicalservices/Site1972/mainpageS1972P5.html

or find by letter: A-F G-L M-R S-Z ITP/Platelet Disorders Idiopathic (Immune) Thrombocytopenia Purpura Innovations and Research Second Opinions Meet the Team Contact Us Return to Blood Disorders Home Clinical Services Idiopathic (Immune) Thrombocytopenia Purpura Second Opinions Second Opinions Please call 617-355-8246 regarding ITP second opinions. To schedule an appointment , call 617-355-8246 To speak with a physician representative , call 617-355-8246 Children's Hospital Boston is the primary pediatric teaching hospital of Harvard Medical School Contact Us Privacy Accessibility Give Now Children's Hospital Boston 300 Longwood Avenue Boston MA 02115

35. Acquired Platelet Function Defect Acquired platelet function defects are nonhereditary diseases or Acquired qualitative platelet disorders; Acquired disorders of platelet function http://www.lifespan.org/ADAM/English/HIE/000546.htm

Careers at Lifespan Volunteer your time Other ways to give Lifespan's A - Z Health Information Library Injury Disease Nutrition Poison ... Prevention Acquired platelet function defect Definition Acquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Alternative Names Acquired qualitative platelet disorders; Acquired disorders of platelet function Causes Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present.

36. UpToDate Use Of Intravenous Immune Globulin In Hematologic Disorders IMMUNE platelet disorders — IVIG has been effective in the management of some but not all antibodyinduced cases of thrombocytopenia. http://patients.uptodate.com/topic.asp?file=lab_med/2169

37. Platelet Disorders (from Blood) --  Britannica Student Encyclopedia platelet disorders (from blood) The inability to produce adequate amounts of platelets is called thrombocytopenia. Persons with this disorder bruise and http://www.britannica.com/ebi/article-197697

Home Browse Newsletters Store ... Subscribe Already a member? Log in This Article's Table of Contents Introduction Composition of Blood Red Cells White Cells ... Blood Disorders and Diseases Platelet Disorders Red Cell Disorders White Cell Disorders Laboratory Examination of Blood Blood Differences Among Animals ... Print this Table of Contents Shopping Price: USD $1495 Revised, updated, and still unrivaled. The Official Scrabble Players Dictionary (Hardcover) Price: USD $15.95 The Scrabble player's bible on sale! Save 30%. Merriam-Webster's Collegiate Dictionary Price: USD $19.95 Save big on America's best-selling dictionary. Discounted 38%! More Britannica products blood  Student Encyclopedia Article Page 16 of 20 blood... (75 of 2893 words) var mm = [["Jan.","January"],["Feb.","February"],["Mar.","March"],["Apr.","April"],["May","May"],["June","June"],["July","July"],["Aug.","August"],["Sept.","September"],["Oct.","October"],["Nov.","November"],["Dec.","December"]]; To cite this page: MLA style: "blood."

38. Diseases From Clotting Problems platelet disorders occur when there are too few platelets, too many platelets or a normal number of platelets that do not function in the normal manner. http://www-admin.med.uiuc.edu/hematology/Ptdiseases.htm

University of Illinois - Urbana/Champaign Carle Cancer Center Hematology Resource Page Patient Resources Problems that result from changes in/disorders of the coagulation cascade. Home Factor V Leiden Antiphospholipid Syndrome General Clotting Information ... Protein S deficiency To understand the possible disorders associated with the blood clotting (coagulation) system, consider the goal of the system: to prevent excess bleeding. If the clotting system can not adequately form clots (thrombi), then the result is a bleeding disorder (hemophilia); if the clotting system forms clots too easily, then the result is formation of excess clots (thrombophilia). For more information on how blood forms clots, please see the web page on general clotting information. Platelet Disorders: Platelet disorders occur when there are too few platelets, too many platelets or a normal number of platelets that do not function in the normal manner. Having too few platelet or platelets that do not function well (for example, aspirin use) can lead to a bleeding tendency (hemophilia). Likewise, too many platelets can predispose to a tendency to clot excessively (thrombophilia). Platelet function can be altered in many different situations; many medications to treat diseases such as strokes and heart attacks were specifically designed to alter the ability of platelets to form clots. There are also a number of diseases that can alter how well a platelet can function.

39. Log In Problems Knowledge of various types of platelet dysfunction in the neonatal population will lead to timely identification of an infant s individual disorder. http://www.medscape.com/viewarticle/497026

Unable to Deliver Requested Page In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. To find out how to adjust your browser settings to accept cookies, please click here Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site. You can read more about our use of cookies in our About Medscape Help WebMD Health

40. CCHS Clinical Digital Library See also. platelet disorders Patient/Family Resources For additional platelet disorders SubTopics, go to General Hematology Clinical Resources http://cchs-dl.slis.ua.edu/clinical/hematology/bleedingdisorders/plateletdisorde

Clinical Resources by Topic: Hematology Platelet Disorders Clinical Resources See also: Platelet Disorders Patient/Family Resources General Hematology Clinical Resources Platelet Disorders Clinical Resources by Sub-Topic: Acquired Platelet Dysfunction Myeloproliferative Disorders Thrombocytopenia von Willebrand Disease For additional Platelet Disorders Sub-Topics, go to General Hematology Clinical Resources Health Sciences Library College of Community Health Sciences The University of Alabama Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

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