41. MedlinePlus Medical Encyclopedia: Peripheral Neuropathy peripheral neuropathy is a failure of the nerves that carry information to and peripheral neuropathy may involve damage to a single nerve or nerve group http://www.nlm.nih.gov/medlineplus/ency/article/000593.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Peripheral neuropathy Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Nervous system Central nervous system Alternative names Return to top Peripheral neuritis; Neuropathy - peripheral; Neuritis - peripheral Definition Return to top Peripheral neuropathy is a failure of the nerves that carry information to and from the brain and spinal cord. This produces pain, loss of sensation, and inability to control muscles. The term peripheral neuropathy can be broken down as follows: "neuro" = nerves, "pathy" = abnormal, and "peripheral" = nerves beyond the brain and spinal cord. Causes, incidence, and risk factors Return to top The peripheral nerves relay information from your central nervous system (brain and spinal cord) to muscles and other organs and from your skin, joints, and other organs back to your brain. Peripheral neuropathy occurs when these nerves fail to function properly, resulting in pain, loss of sensation, or inability to control muscles. In some cases, the failure of nerves that control blood vessels, intestines, and other organs results in abnormal blood pressure, digestion problems, and loss of other basic body processes. Peripheral neuropathy may involve damage to a single nerve or nerve group (

42. PERIPHERAL NEUROPATHY The treatment of peripheral neuropathy is difficult. Stopping might put you at greater risk than having peripheral neuropathy. http://www.acor.org/diseases/hematology/MPD/neurop.html

PERIPHERAL NEUROPATHY Written by Harrriet S. Gilbert, M.D. to MPD-NET Discussion/Support Group 1997 Sorry to hear about your burning toes. This can be a terrible symptom because of its persistence. In patients with elevated platelets and /or hematocrits the microcirculation may be affected and the patient may experience "dysesthesias" or "paresthesias"(abnormal and uncomfortable sensations in response to stimuli that are not there - such as burning, numbness, tingling, pain) of the terminal digits (fingers, toes). The same symptoms can accompany disturbances of the nerves that supply those areas. This is called "neuropathy" and when it involves the extremities it is called "peripheral neuropathy". This occurs in many diseases and is a sign of nerve inflammation. Interferon may produce neuropathy. The treatment of peripheral neuropathy is difficult. If you stopped the IFN you might or might not get relief but your heme/onc doctor must make that decision. Stopping might put you at greater risk than having peripheral neuropathy. There are some medications that can be used to diminish or disappear the sensations, such as Elavil. You might ask your doctor about this. There is also a topical medicine called Zostrix that may help. Please let me know what happens.

43. Peripheral Neuropathy Penn State Hershey Medical Center provides world class care and services to patients. http://www.hmc.psu.edu/healthinfo/pq/peripheralneuropathy.htm

44. Regular Review: Peripheral Neuropathy -- Hughes 324 (7335): 466 -- BMJ peripheral neuropathy is common, often distressing, and sometimes Patients with peripheral neuropathy may present with altered sensation, pain, http://bmj.bmjjournals.com/cgi/content/full/324/7335/466

Home Help Search Archive ... Table of Contents Author Keyword(s) Vol Page [Advanced] This article Extract PDF Respond to this article Read responses to this article ... View citation map Services Email this article to a friend Find similar articles in BMJ Find similar articles in ISI Web of Science Find similar articles in PubMed ... Read articles citing this article Search for citing articles in: ISI Web of Science (14) PubMed PubMed Citation Articles by Hughes, R. A C Related content Neuropathology Other Neurology Neurological injury Related Article BMJ 2002;324:466-469 ( 23 February ) Clinical review Regular review Peripheral neuropathy Richard A C Hughes professor of neurology Department of Neuroimmunology, Guy's Campus, Guy's, King's, and St Thomas's School of Medicine, London SE1 1UL Peripheral neuropathy is common, often distressing, and sometimes disabling or even fatal. The population prevalence is about 2400 per 100 000 (2.4%), rising with age to 8000 per 100 000 (8%). In Europe the commonest cause is diabetes mellitus, which can

45. Peripheral Neuropathy peripheral neuropathy is a common neurological disorder resulting from damage to the peripheral nerves. http://healthlink.mcw.edu/article/921448615.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Peripheral Neuropathy Peripheral neuropathy is a common neurological disorder resulting from damage to the peripheral nerves. It may be caused by diseases of the nerves or as the result of systemic illnesses. Many neuropathies have well-defined causes such as diabetes, uremia, or nutritional deficiencies. In fact, diabetes is one of the most common causes of peripheral neuropathy. Other causes include mechanical pressure such as compression or entrapment, direct trauma, penetrating injuries, contusions, fracture or dislocated bones; pressure involving the superficial nerves (ulna, radial, or peroneal) which can result from prolonged use of crutches or staying in one position for too long, or from a tumor; intraneural hemorrhage; exposure to cold or radiation; and vascular or collagen disorders such as atherosclerosis, systemic lupus erythematosus, scleroderma, sarcoidosis, rheumatoid arthritis, and polyarteritis nodosa. A common example of entrapment neuropathy is carpal tunnel syndrome, which has become more common because of the increasing use of computers. Although the causes of peripheral neuropathy are diverse, they produce common symptoms including weakness, numbness, paresthesia (abnormal sensations such as burning, tickling, pricking or tingling) and pain in the arms, hands, legs and/or feet. A large number of cases are of unknown cause.

46. Peripheral Neuropathy peripheral neuropathy is a term used to describe disorders of your peripheral peripheral neuropathy often affects people with diabetes and autoimmune http://www.cnn.com/HEALTH/library/DS/00131.html

International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Autos SERVICES Video E-mail Newsletters Your E-mail Alerts RSS ... Contact Us SEARCH Web CNN.com In association with: DIABETES AND ENDOCRINE SYSTEM Diabetes Complications Peripheral neuropathy Diabetic retinopathy Autonomic neuropathy INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Peripheral neuropathy From MayoClinic.com Special to CNN.com Overview Peripheral neuropathy Neuropathies may affect just one nerve (mononeuropathy) or several nerves (polyneuropathy). Your nerves provide communication between your brain and your muscles, skin, internal organs and blood vessels. When damaged, your nerves can't communicate properly, and that miscommunication causes symptoms such as pain or numbness. Peripheral neuropathy often affects people with diabetes and autoimmune diseases such as rheumatoid arthritis and lupus. Certain vitamin deficiencies, some medications and alcoholism can also damage peripheral nerves.

47. Treatment Of Peripheral Neuropathy - Guide To Peripheral Neuropathy No medical treatments now exist that can cure inherited peripheral neuropathy. However, there are treatments for many other forms of peripheral neuropathy. http://arthritis.about.com/od/nervepain/a/neuropathyguide_5.htm

var zLb=1; zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a02' About Arthritis Arthritis Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Arthritis newsletter! See Online Courses Search Arthritis Stay up to date! Compare Prices Email to a friend ... Print this page Related Resources - Peripheral Neuropathy Nerve Pain (Neuralgias) What are Pinched Nerves? Where Does it Hurt? Related Resources - Peripheral Neuropathy A to Z: Pain Relief The Pain Relief Quiz The Pain Quiz: Acute vs. Chronic Pain Related Resources - Peripheral Neuropathy Muscle Pain - Muscle Conditions Lyme Disease Screening Quiz Lyme Disease Quiz - Test Your Knowledge Most Popular Arthritis Screening Quiz Rheumatoid Arthritis Screening Quiz Quiz: Is it Rheumatoid or Osteoarthritis? Gout Screening Quiz ... Osteoarthritis Screening Quiz What's Hot Insomnia Arthritis Angel Award The Pain Quiz - Acute vs. Chronic Pain What is Arthrodesis? ... Arthritis Without Pain adunitCM(150,100,'x55') Guide To Peripheral Neuropathy from National Institute of Neurological Disorders and Stroke Part 5 of 5 - Treatment Of Peripheral Neuropathy What treatments are available for peripheral neuropathy?

48. Neuropathy (Peripheral) - Guide To Peripheral Neuropathy A fivepart guide to peripheral neuropathy (damage to the peripheral nerves). More than 100 types of peripheral neuropathy have been identified, http://arthritis.about.com/od/nervepain/a/neuropathyguide.htm

var zLb=1; zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a02' About Arthritis Joint Pain / Surgery Nerve Pain - Neuralgia Neuropathy (Peripheral) - Guide To Peripheral Neuropathy Arthritis Essentials Arthritis Symptoms Is It Arthritis? ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Arthritis newsletter! See Online Courses Search Arthritis Stay up to date! Compare Prices Email to a friend ... Print this page Related Resources - Peripheral Neuropathy Nerve Pain (Neuralgias) What are Pinched Nerves? Where Does it Hurt? Related Resources - Peripheral Neuropathy A to Z: Pain Relief The Pain Relief Quiz The Pain Quiz: Acute vs. Chronic Pain Related Resources - Peripheral Neuropathy Muscle Pain - Muscle Conditions Lyme Disease Screening Quiz Lyme Disease Quiz - Test Your Knowledge Most Popular Arthritis Screening Quiz Rheumatoid Arthritis Screening Quiz Quiz: Is it Rheumatoid or Osteoarthritis? Gout Screening Quiz ... Osteoarthritis Screening Quiz What's Hot Insomnia Arthritis Angel Award The Pain Quiz - Acute vs. Chronic Pain

49. SF AIDS Fdn: BETA 3/97 -- Peripheral Neuropathy This article from the March 97 Bulletin of Experimental Treatments for AIDS covers peripheral neuropathy, which affects primarily the sense of touch in the http://www.sfaf.org/treatment/beta/b32/b32pn.html

Published in the Bulletin of Experimental Treatments for AIDS March 1997 issue, by the San Francisco AIDS Foundation. March 1997 Table of Contents Main Page beta@sfaf.org Peripheral Neuropathy by Mark Bowers The ancient Greeks were the first to enumerate the 5 senses: vision, hearing, taste, smell and touch. Aristotle further divided the sense of touch into hard-soft, hot-cold and rough-smooth components, quite similar to the findings of modern neurological research that supports the existence of different types of peripheral nerves in the body that carry the sensations of cold, warmth, touch and pain. HIV infection is associated with several kinds of peripheral neuropathy that affect primarily the sense of touch in the hands and feet, but may also cause more severe symptoms such as muscle weakness. HIV does not directly infect neurons (nerve cells). Instead, it may damage the cells that surround nerves, unraveling neural insulation and slowing, garbling or stopping the transmission of information to and from the brain. Abnormal macrophage activation is associated with the pathology. Some of the drugs that are used to treat HIV or associated opportunistic infections (OI) may damage axons, the long, narrow connecting processes of neurons that communicate with muscles, tissues and organs. Symptoms of peripheral neuropathy may arise at any time during HIV infection. Neuropathy is reported at a rate of 6-8% during the acute retroviral syndrome that often occurs shortly after infection. Neuropathy may affect people with asymptomatic HIV disease, manifesting in syndromes ranging from mononeuritis (inflammation of a single nerve) and mononeuropathy (disease of a single nerve), to polyneuropathies that affect multiple nerves and can lead to paralysis. Most commonly, peripheral neuropathy develops in people with symptomatic HIV disease or AIDS. For these individuals, the symptoms of painful, burning feet or numbness in the feet and/or hands are familiar and often disabling.

50. Peripheral Neuropathy peripheral neuropathy is damage to the nerves just under the skin. peripheral neuropathy may include the following symptoms http://www.tthhivclinic.com/perineur.htm

INFORMATION ON HIV Go to other sections: Select a link HIV Overview/Stages of Infection The Life Cycle of HIV Disease Symptoms Fact Sheets Symptoms: Select a link Apthous Ulcers Candidiasis Cytomegalovirus (CMV) Cryptococcal Meningitis Cryptosporidiosis Herpes Zoster (Shingles) Histoplasmosis Kaposi’s Sarcoma Lymphoma Mycobacterium Avium Complex (MAC) Oral Hairy Leukoplakia PAP test/PAP smear and HIV paptest PAP test/PAP smear and HIV Peripheral Neuropathy Progressive Multifocal Leukoencephalopathy (PML) Toxoplasmosis (Toxo) Wasting Ontario HIV Clinics' Fact Sheet Peripheral Neuropathy What is Peripheral Neuropathy? Peripheral Neuropathy is damage to the nerves just under the skin. It can be caused by HIV itself and/or medications such as ddI, ddC, d4T, and some chemotherapies. What do I look for? Peripheral neuropathy may include the following symptoms: numbness and tingling of fingers, hands, toes and feet A person with these symptoms should seek medical attention. Can Peripheral Neuropathy be prevented? There is no known prevention for peripheral neuropathy.

51. Neuropathy Trust: Peripheral Neuropathy peripheral neuropathy Preface. The information that you are about to read was first in a Neuropathy Trust publication entitled peripheral neuropathy http://www.neuropathy-trust.org/mainpages/education/pn/preface.htm

Home Biography Join Today Support ... External Resources PERIPHERAL NEUROPATHY: Preface The information that you are about to read was first published in a Neuropathy Trust publication entitled We sincerely hope that this informaton gives you a clearer insight into this neuropathic condition, what causes it, and what you can do to help yourself if you are so affected. Kind Regards, Carpe Diem, Andrew Keen, MInstF next: what is pn? Purchase the booklet Home Bio ... Resources Site Update: www.neurocentre.com privacy security Web site authoring: KeenDynamics Preferred Screen Resolution Flash Status: Enabled ::section menu:: Preface What is PN? Symptoms The Peripheral Nerve ... Purchase the Booklet

52. Peripheral Neuropathy Medic8 Family Health Guide your trusted source for health information online. More than 500 health-related articles written by qualified health http://www.medic8.com/healthguide/articles/peripheralneuropathy.html

"Medic8.com - Your trusted source for health information online" Family Health Cosmetic Surgery Medical Dictionary Medical Insurance ... Help HEALTH GUIDE Family Health Cosmetic Surgery Health Insurance Women's Health ... Medical Dictionary TELL A FRIEND Tell A Friend About This Page TOPICS/THEMES Allergies Alternative Health Arthritis Asthma ... Women's Health MISCELLANEOUS Interactive Tutorials Health Products Medical News Medic8 Search ... About Medic8 PERIPHERAL NEUROPATHY - a patient's guide Dr Geoff Green - Physician What is it? Peripheral neuropathy is a group of conditions affecting the nerves outside the brain and spinal cord, interfering with their function. The term generally excludes single nerve lesions (mononeuropathy) due to entrapment of the nerve or trauma. The nerves at the extremities (e.g. hands and feet) are most commonly involved. The nerves affected may be sensory (touch), motor (activating the muscles) or autonomic (feeding organs and controlling sweating and blood pressure), or a combination of these types.

53. THE MERCK MANUAL, Sec. 14, Ch. 183, Disorders Of The Peripheral Nervous System peripheral neuropathy. A syndrome of sensory loss, muscle weakness and atrophy, decreased deep tendon reflexes, and vasomotor symptoms, alone or in any http://www.merck.com/pubs/mmanual/section14/chapter183/183f.htm

var locationOverride = "http://www.merck.com/pubs/"; This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 14. Neurologic Disorders Chapter 183. Disorders Of The Peripheral Nervous System Topics [General] Lower And Upper Motor Neuron Disorders Nerve Root Disorders Plexus Disorders ... Disorders Of Neuromuscular Transmission Peripheral Neuropathy A syndrome of sensory loss, muscle weakness and atrophy, decreased deep tendon reflexes, and vasomotor symptoms, alone or in any combination. Etiology Trauma is the most common cause of a localized injury to a single nerve. Violent muscular activity or forcible overextension of a joint may produce a focal neuropathy, as may repeated small traumas (eg, tight gripping of small tools, excessive vibration from air hammers). Pressure or entrapment paralysis usually affects superficial nerves (ulnar, radial, peroneal) at bony prominences (eg, during sound sleep or during anesthesia in thin or cachectic persons and often in alcoholics) or at narrow canals (eg, in carpal tunnel syndrome). Pressure paralysis may also result from tumors, bony hyperostosis, casts, crutches, or prolonged cramped postures (eg, in gardening). Hemorrhage into a nerve and exposure to cold or radiation may cause neuropathy. Mononeuropathy may result from direct tumor invasion. Acute Viral Encephalitis and Aseptic Meningitis in Ch. 176).

54. Foot Ankle Institute Statistics peripheral neuropathy Classifying Treatment Complications NonHealing Etiology Nerves affected Diagnosing peripheral neuropathy http://www.feetnet.com/diab/peri/

55. Peripheral Neuropathy Menu peripheral neuropathy Menu. These are articles related to peripheral neuropathy issues. Please feel free to browse http://neuro-www.mgh.harvard.edu/neurowebforum/PeripheralNeuropathyMenu.html

Peripheral Neuropathy Menu These are articles related to Peripheral Neuropathy issues. Please feel free to browse... ATTENTION: The Neurology Webforums have changed software...you cannot reply to any of these posts! Please go immediately to the Main Neurology WebForum page for more information! causes of intermittent neuropath (2/25/97) 7:19 PM causes of intermittent periphera (2/25/97) 5:15 AM breathing irregularity (2/25/97) 5:09 AM unmentioned causes breathing ir (2/25/97) 5:04 AM ... First Posting (9/5/96) 12:09 PM IMPORTANT: If this page seems to be missing recently added documents, click the "Reload Page" button on your Web Browser to update the menu. Return To the main Neurology Web-Forum Page.

56. A Treatment Lesson On Peripheral Neuropathy An easyto-read guide for people living with HIV AIDS with lessons on important treatment issues, from AIDSmeds.com. http://www.aidsmeds.com/lessons/Neuropathy1.htm

Join our confidential mailing list! Enter your email address: LESSONS DRUGS FORUMS BLOGS ... HOME Peripheral Neuropathy What Is It? Peripheral neuropathy results from injury to the peripheral nerves in the body. These nerves carry signals between the central nervous system (the brain and spinal column) and the muscles, skin, and internal organs. When peripheral neuropathy first develops, people often report a tingling or prickling in the toes, although it can also start in the fingers. Over time, the tingling gradually spreads up the feet or hands and worsens into a burning, shooting, and/or throbbing pain. People who have severe peripheral neuropathy may experience extreme pain and may have difficulty walking, sometimes requiring the assistance of a cane or wheelchair to move around. People who have peripheral neuropathy usually experience symptoms on both sides of their bodies. In other words, peripheral neuropathy almost always occurs in both feet and/or both hands. The sensations can be either constant or periodic. Sometimes they may not be noticeable, while at other times they may be extremely bothersome. Peripheral Neuropathy Index What is it?

57. Project Inform's Peripheral Neuropathy [ HIV / AIDS Treatment Information ] Project Inform is a national organization working to end the AIDS epidemic. We provide information on the diagnosis and treatment of HIV disease, http://www.projinf.org/fs/sneuro.html

Search Contact Us Feedback Calendar ... Site Map Peripheral Neuropathy May 1998 View PDF Table of Contents Managing Neuropathy Nerve Growth Factor Diagnosis and Management of Sensory Neuropathy Epidemiology ... References Peripheral neuropathy (PN), or damage to the peripheral nerves (nerves outside the brain or spinal chord), is a potential side effect of many anti-HIV therapies or HIV itself and can greatly affect quality of life. It is often caused by a breakdown of the myelin sheath, the coating around nerve fibers that acts as an electrical insulator. Early signs of PN can include a sensation of burning, tingling, or numbness in the fingers or toes. Some people describe an electric shock sensation or a strange plastic or scab-like sensation when something touches their fingers or toes. In severe cases, touching the affected area can feel like touching an open wound. In some cases, there may be a deep soreness or shooting pains in the muscles of the legs and lower arms that may be transient but always affect the same general area. In more serious cases, severe pain and altered feedback in the nervous system may even interfere with walking. Currently, there are no effective treatments that can stop or reverse this nerve damage. The most effective management of PN includes identifying the cause and, if possible, eliminating it. In many cases, the best treatment is simply pain management, and the type of medication used is generally determined by the severity of the PN.

58. Peripheral Neuropathy : CancerBACUP Information on the condition of peripheral neuropathy which is developed by many people with cancer or undergoing cancer treatments. http://www.cancerbacup.org.uk/Resourcessupport/Symptomssideeffects/Othersymptoms

@import "/stylesheet-site.css"; Search Peripheral neuropathy Peripheral neuropathy is a term used to describe changes in the way that particular nerves work. Many people who have cancer, or cancer treatments, may develop peripheral neuropathy. This information is about the condition. The nervous system Peripheral neuropathy Symptoms of peripheral neuropathy Peripheral neuropathy, cancer and its treatments ... References The nervous system The nervous system is made up of the brain, the spinal cord, and a complicated network of nerves that thread throughout the body. It has two main divisions: the central nervous system (CNS), which consists of the brain and spinal cord the peripheral nervous system (PNS), which consists of nerves that carry messages between the brain, spinal cord and the rest of the body (such as the arms and legs, hands and feet). A diagram showing the nerves of the body. (d) Nerves carry nerve impulses back and forth between the areas of the body and the brain. Nerves are made up of nerve cells called neurons Neurons are very thin. Some are very small, and some can be 3 feet (1 metre) long. Many are shaped a bit like stars that have been pulled at each end so that they have long fingers. The fingers of one nerve cell reach almost to the next neuron, but there is a gap between them.

59. Peripheral Neuropathy The peripheral nervous system can be involved in a wide range of medical disorders with various pathophysiologies. This diverse array of possible etiologies http://www.clevelandclinicmeded.com/diseasemanagement/neurology/pneuro/pneuro.ht

Published February 9, 2004 Robert W. Shields, Jr, MD Department of Neurology Print Chapter The Cleveland Clinic Foundation The peripheral nervous system can be involved in a wide range of medical disorders with various pathophysiologies (Table 1) It may be affected by numerous toxins, both drugs (Table 2) and industrial agents (Table 3) chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and multifocal motor neuropathy with conduction block syndrome (MMNCB). Finally, a host of hereditary polyneuropathies may cause a wide range of peripheral neuropathy syndromes (Table 4) This diverse array of possible etiologies can make the diagnosis of peripheral neuropathies quite challenging. Nevertheless, diagnosis can be facilitated with a systematic approach that classifies the peripheral neuropathy on the basis of clinical features, taking into account the type of peripheral nerve fiber that may be involved ( ie, sensory, motor, or autonomic), the distribution or pattern of peripheral nerve-fiber involvement (ie, generalized and symmetric versus asymmetric and multifocal), and lastly, the mode of evolution (ie, acute, subacute, or chronic). Definition Prevalence Pathophysiology Signs and ... References DEFINITION Peripheral neuropathy, in the broadest sense, refers to a scope of clinical syndromes

60. Peripheral Neuropathy For lighter forms of peripheral neuropathy, paracetamol, 500 mg 6 times daily or In a study of HIVpositive individuals with peripheral neuropathy, http://www.hivnet.org/OverHivEnAids/Alternatief/BrochureBijwerkingenEngels/Perip

HIV and HIV Medication: Complaints, Side Effects, and Possible Treatments Peripheral neuropathy Treatment [Bartlett-jg], [Hegarty-a], [Van Bergen-Jeam], [Merigan, jr-tc] Despite the debilitating symptoms of peripheral neuropathy, it is advisable not to take too much rest or too little exercise. Movement is especially important for the muscles, joints, and general condition. It may be sensible to avoid tight shoes, to walk only short distances, and once in a while to place the feet in an ice bath. For lighter forms of peripheral neuropathy, paracetamol , 500 mg 6 times daily or ibuprofen 200 mg 4 times daily can be used. Ibuprofen belongs to the family of anti-inflammatory analgesics which cause relatively few stomach problems. Should paracetamol, ibuprofen, or another anti-inflammatory analgesic have insufficient effect, then it is possible to try so-called tricyclic antidepressants. These have the characteristic of easing pain in low dosages without exhibiting any mood-changing effects. Amitriptyline can, for example, be used in a dosage of 10-25 mg prior to going to sleep. If necessary, the dosage can be raised to 50-150 mg per day. This medication can cause tiredness, especially in the beginning, but this disappears for the most part as the treatment progresses. The tiredness resulting from amitriptyline can actually be a benefit if sleeplessness is also a problem. Other side effects include dry mouth and constipation. An alternative is to switch over to another tricyclic anti-depressant such as

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 3     41-60 of 118    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20